Cytosine methylation changes in enhancer regions of core pro-fibrotic genes characterize kidney fibrosis development

Genome Biology

Volumn 14, Issue 10, 2013, Pages

  Ko, Yi An ^a   Mohtat, Davoud ^a   Suzuki, Masako ^b   Park, Ae S D ^a   Izquierdo, Maria C ^a   Han, Sang Y ^a   Kang, Hyun M ^a   Si, Han ^a   Hostetter, Thomas ^d   Pullman, James M ^c   Fazzari, Melissa ^b   Verma, Amit ^b   Zheng, Deyou ^b   Greally, John M ^b   Susztak, Katalin ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^c MONTEFIORE MEDICAL CENTER   (United States)

^d CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; CYTOSINE; TRANSCRIPTION FACTOR;

AGED; ARTICLE; CHRONIC KIDNEY DISEASE; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; ENHANCER REGION; EPIGENETICS; FEMALE; GENE CONTROL; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE INTERACTION; GENE REPLICATION; GENE SEQUENCE; GENETIC ASSOCIATION; HUMAN; HUMAN TISSUE; KIDNEY DYSFUNCTION; KIDNEY FIBROSIS; KIDNEY PARENCHYMA; KIDNEY TUBULE DISORDER; MAJOR CLINICAL STUDY; MALE; NUCLEOTIDE SEQUENCE; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN METHYLATION; BINDING SITE; CASE CONTROL STUDY; CHRONIC KIDNEY FAILURE; CLUSTER ANALYSIS; DNA METHYLATION; DRUG EFFECT; FIBROSIS; GENE EXPRESSION PROFILING; GENE REGULATORY NETWORK; GENETIC TRANSCRIPTION; GENETICS; KIDNEY; METABOLISM; MIDDLE AGED; NUCLEOTIDE MOTIF; PATHOLOGY; POSITION WEIGHT MATRIX; REPRODUCIBILITY;

AGED; BASE SEQUENCE; BINDING SITES; CASE-CONTROL STUDIES; CLUSTER ANALYSIS; CYTOSINE; DNA METHYLATION; ENHANCER ELEMENTS, GENETIC; FIBROSIS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORKS; HUMANS; KIDNEY; MIDDLE AGED; NUCLEOTIDE MOTIFS; POSITION-SPECIFIC SCORING MATRICES; RENAL INSUFFICIENCY, CHRONIC; REPRODUCIBILITY OF RESULTS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 84884994148     PISSN: None     EISSN: 1474760X     Source Type: Journal    
DOI: 10.1186/gb-2013-14-10-r108     Document Type: Article

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