Skin pretreatment with microneedles prior to pilocarpine iontophoresis increases sweat production

Clinical Physiology and Functional Imaging

Volumn 33, Issue 6, 2013, Pages 436-440

  Wing, David ^a   Prausnitz, Mark R ^b   Buono, Michael J ^a  

^a SAN DIEGO STATE UNIVERSITY   (United States)

^b GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Cystic fibrosis; Iontophoresis; Microneedles; Pilocarpine; Sweat testing

Indexed keywords

PILOCARPINE;

ADULT; ARTICLE; CONTROLLED STUDY; CYSTIC FIBROSIS; ELECTRIC RESISTANCE; FEMALE; HUMAN; HYPOTHESIS; IONTOPHORESIS; MALE; METHODOLOGY; MICRONEEDLE; OSMOLALITY; PAIN; PREMEDICATION; PRIORITY JOURNAL; SKIN PERMEABILITY; STRATUM CORNEUM; SWEAT GLAND; SWEATING;

CYSTIC FIBROSIS; IONTOPHORESIS; MICRONEEDLES; PILOCARPINE; SWEAT TESTING;

ADMINISTRATION, CUTANEOUS; ADULT; CALIFORNIA; CYSTIC FIBROSIS; ELECTRIC IMPEDANCE; EQUIPMENT DESIGN; FEMALE; HUMANS; IONTOPHORESIS; MALE; MINIATURIZATION; MUSCARINIC AGONISTS; NEEDLES; PERMEABILITY; PILOCARPINE; PREDICTIVE VALUE OF TESTS; SKIN; SKIN ABSORPTION; SWEAT; SWEATING; TIME FACTORS; UP-REGULATION; YOUNG ADULT;

EID: 84884986700     PISSN: 14750961     EISSN: 1475097X     Source Type: Journal    
DOI: 10.1111/cpf.12053     Document Type: Article

References (26)

1. ®): a new intradermal vaccine for seasonal influenza. Expert Rev Vaccines (2010); 9: 1399-1409.
2. Aust M, Fernandes D, Kolokythas P, Kaplan H, Vogt P. Percutaneous collagen induction therapy: an alternative treatment for scars, wrinkles, and skin laxity. Plast Reconstr Surg (2008); 121: 1421-1429.
3. Bijur P, Silver W, Gallagher E. Reliability of the visual analog scale for measurement of acute pain. Acad Emerg Med (2001); 8: 1153-1157.
4. Chernick C. Test for the concentration of electrolytes in cystic fibrosis of the pancreas utilizing pilocarpine by iontophoresis, by Lewis E. Gibson and Robert E. Cooke, Pediatrics; 1959;24:545-549. Pediatrics (1998); 102 (1 Pt 2): 230-231.
5. Coltman C, Atwell R. Sweat collection in cystic fibrosis. Report of a simplified method employing pilocarpine iontophoresis and cellulose sponge. Ohio Med (1962); 58: 681-682.
6. Daddona P, Matriano J, Mandema J, Maa Y. Parathyroid hormone (1-34)-coated microneedle patch system: clinical pharmacokinetics and pharmacodynamics for treatment of osteoporosis. Pharm Res (2011); 28: 159-165.
7. Delgado-Charro M, Guy R. Iontophoresis: application in drug delivery and noninvasive monitoring. STP Pharma Sciences (2001); 11: 403-414.
8. Duan D, Moeckly C, Gysbers J, Novak C, Prochnow G, Siebenaler K, Hansen K. Enhanced delivery of topically-applied formulations following skin pre-treatment with a hand-applied, plastic microneedle array. Curr Drug Deliv (2011); 8: 557-565.
9. Fang J, Lee W, Shen S, Fang Y, Hu C. Enhancement of topical 5-aminolaevulinic acid delivery by erbium:YAG laser and microdermabrasion: a comparison with iontophoresis and electroporation. Br J Dermatol (2004); 151: 132-140.
10. Gill H, Denson D, Burris B, Prausnitz M. Effect of microneedle design on pain in human volunteers. Clin J Pain (2008); 24: 585-594.
11. Gupta J, Gill H, Andrews S, Prausnitz M. Kinetics of skin resealing after insertion of microneedles in human subjects. J Control Release (2011); 154: 148-155.
12. Khan A, Yasir M, Asif M, Chauhan I, Singh A, Sharma R, Pradeep S, Rai S. Iontophoretic drug delivery: history and applications. JAPS (2011); 1: 11-24.
13. Kim C, Park J, Prausnitz M. Microneedles for drug and vaccine delivery. Adv Drug Deliv Rev (2012); 64: 1547-1568.
14. LeGrys V. Assessment of sweat-testing practices for the diagnosis of cystic fibrosis. Arch Pathol Lab Med (2001); 125: 1420-1424.
15. LeGrys V, Retsch-Bogart G. Urticaria associated with the pilocarpine iontophoresis sweat test. Pediatr Pulmonol (1997); 24: 296-297.
16. Lin W, Cormier M, Samiee A, Griffin A, Johnson B, Teng C, Hardee G, Daddona P. Transdermal delivery of antisense oligonucleotides with microprojection patch (Macroflux) technology. Pharm Res (2001); 18: 1789-1793.
17. McAllister D, Wang P, Davis S, Park J, Canatella P, Allen M, Prausnitz M. Microfabricated needles for transdermal delivery of macromolecules and nanoparticles: fabrication methods and transport studies. Proc Natl Acad Sci USA (2003); 100: 13755-13760.
18. Rawat S, Vengurlekar S, Rakesh B, Jain S, Srikarti G. Transdermal delivery by iontophoresis. Indian J Pharm Sci (2008); 70: 5-10.
19. Sato K, Dobson R. Regional and individual variations in the function of the human eccrine sweate gland. J Invest Dermatol (1970); 54: 443-449.
20. Shah U, Roberts M, Orlu Gul M, Tuleu C, Beresford M. Needle-free and microneedle drug delivery in children: a case for disease-modifying antirheumatic drugs (DMARDs). Int J Pharm (2011); 416: 1-11.
21. Sloan J, Saltani K. Iontophoresis in dermatology. J Am Acad Dermatol (1986); 15: 671-684.
22. Sullivan S, Koutsonanos D, Del Pilar Martin M, Lee J, Zarnitsyn V, Choi S, Murthy N, Compans R, Skountzou I, Prausnitz M. Dissolving polymer microneedle patches for influenza vaccination. Nat Med (2010); 16: 915-920.
23. Watts J. Alternative iontophoresis medications. Phys Ther Prod (2005); http://www.ptproductsonline.com/issues/articles/2005-09_04.asp.
24. Wermeling D, Banks S, Hudson D, Gill H, Gupta J, Prausnitz M, Stinchcomb A. Microneedles permit transdermal delivery of a skin-impermeant medication to humans. Proc Natl Acad Sci USA (2008); 105: 2058-2063.
25. Wu X, Todo H, Sugibayashi K. Enhancement of skin permeation of high molecular compounds by a combination of microneedle pretreatment and iontophoresis. J Control Release (2007); 118: 189-195.
26. You S, Noh Y, Park H, Han M, Lee S, Shin S, Cho C. Effect of applying modes of the polymer microneedle-roller on the permeation of L-ascorbic acid in rats. J Drug Target (2010); 18: 15-20.