AMP-activated protein kinase counteracts brain-derived neurotrophic factor-induced mammalian target of rapamycin complex 1 signaling in neurons

Journal of Neurochemistry

Volumn 127, Issue 1, 2013, Pages 66-77

  Ishizuka, Yuta ^a,b   Kakiya, Naomasa ^a   Witters, Lee A ^c   Oshiro, Noriko ^d,e   Shirao, Tomoaki ^b   Nawa, Hiroyuki ^a   Takei, Nobuyuki ^a  

^a NIIGATA UNIVERSITY   (Japan)

^b GUNMA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c DARTMOUTH MEDICAL SCHOOL   (United States)

^d KOBE UNIVERSITY   (Japan)

^e MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

AMPK; BDNF; mTOR; neuron; protein synthesis; translation

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; FIBROBLAST GROWTH FACTOR 2; GLUCOSE; HAMARTIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MAMMALIAN TARGET OF RAPAMYCIN; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; S6 KINASE; TUBERIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN CELL; CARBOXY TERMINAL SEQUENCE; CELL METABOLISM; CELL SURVIVAL; CONTROLLED STUDY; CULTURE MEDIUM; EMBRYO; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; FETUS; GLUCOSE DEPRIVATION; INTRACELLULAR SIGNALING; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; RAT; TRANSLATION REGULATION;

AMPK; BDNF; MTOR; NEURON; PROTEIN SYNTHESIS; TRANSLATION;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; BRAIN-DERIVED NEUROTROPHIC FACTOR; CELLS, CULTURED; CEREBRAL CORTEX; DEOXYGLUCOSE; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ELECTROPORATION; FIBROBLASTS; GLUCOSE; HYPOGLYCEMIC AGENTS; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; METFORMIN; METHIONINE; MULTIPROTEIN COMPLEXES; NEURONS; ONCOGENE PROTEIN V-AKT; PHOSPHORYLATION; RATS; RATS, SPRAGUE-DAWLEY; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES;

MAMMALIA; RAPTORES;

EID: 84884908147     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/jnc.12362     Document Type: Article

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