Tuberin phosphorylation regulates its interaction with hamartin. Two proteins involved in tuberous sclerosis

Journal of Biological Chemistry

Volumn 276, Issue 24, 2001, Pages 21017-21021

  Aicher, Lauri D ^b   Campbell, Jean S ^b   Yeung, Raymond S ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; GENES; GROWTH KINETICS; MUTAGENESIS; PATHOLOGY; TUMORS;

PHOSPHORYLATION;

PROTEINS;

HAMARTIN; PERVANADATE; SERINE; TUBERIN; TYROSINE; PROTEIN; RECOMBINANT PROTEIN; REPRESSOR PROTEIN; TUBEROUS SCLEROSIS COMPLEX 1 PROTEIN; TUMOR SUPPRESSOR PROTEIN;

ANIMAL CELL; ARTICLE; CANCER INHIBITION; CELL STRAIN COS1; CONTROLLED STUDY; GENE FUNCTION; GENE MUTATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; TUBEROUS SCLEROSIS; TUMOR GROWTH; TUMOR SUPPRESSOR GENE; ANIMAL; ARMYWORM; CELL LINE; CELL STRAIN 3T3; CERCOPITHECUS; CHEMISTRY; GENETIC TRANSFECTION; GENETICS; HELA CELL; METABOLISM; PHOSPHORYLATION; SITE DIRECTED MUTAGENESIS;

ANIMALIA;

3T3 CELLS; ANIMALS; CELL LINE; CERCOPITHECUS AETHIOPS; COS CELLS; GENES, TUMOR SUPPRESSOR; HELA CELLS; HUMANS; MICE; MUTAGENESIS, SITE-DIRECTED; PHENOTYPE; PHOSPHORYLATION; PROTEINS; RECOMBINANT PROTEINS; REPRESSOR PROTEINS; SPODOPTERA; TRANSFECTION; TUBEROUS SCLEROSIS; TUMOR SUPPRESSOR PROTEINS;

EID: 0035877758     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.C100136200     Document Type: Article

References (22)

1. Gomez, M. R. (1999) in Tuberous Sclerosis, (Gomez, M. R., Sampson, J. R., and Whittemore, V. H., eds) 3d Ed., pp. 10-23, Oxford University Press, New York
2. Roach, E. S., Gomez, M. R., and Northrup, H. (1998) J. Child Neurol. 13, 624-628
3. van Slegtenhorst, M., de Hoogt, R., Hermans, C., Nellist, M., Janssen, B., Verhoef, S., Lindhout, D., van deh Ouweland, A., Halley, D., Young, J., Burley, M., Jeremiah, S., Woodward, K., Nahmias, J., Fox, M., Ekong, R., Osborne, J., Wolfe, J., Povey, S., Snell, R. G., Cheadle, J. P., Jones, A. C., Tachatake, M., Ravine, D., Sampson, J. R., et al. (1997) Science 277, 805-808
4. The European Chromosome 16 Tuberous Sclerosis Consortium (1993) Cell 75, 1305-1315
5. Jin, F., Wienecke, R., Xiao, G., Maize, J. C., DeClue, J. E., and Yeung, R. S. (1996) Proc. Natl. Acad. Sci. U. S. A. 9, 9154-9159
6. Orimoto, K., Tsuchiya, H., Kobayashi, T., Matsuda, T., and Hino, O. (1996) Biochem. Biophys. Res. Comm. 219, 70-75
7. Soucek, T., Pusch, O., Wienecke, R., DeClue, J. E., and Hengstschlager, M. (1997) J. Biol. Chem. 272, 29301-29308
8. Soucek, T., Yeung, R. S., and Hengstschlager, M. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 15653-15658
9. Ito, N., and Rubin, G. M. (1999) Cell 96, 529-539
10. Rennebeck, G., Kleymenova, E. V., Anderson, R., Yeung, R. S., Artzt, K., and Walker, C. L. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 15629-15634
11. Wienecke, R., Konig, A., and DeClue, J. E. (1995) J. Biol. Chem. 270, 16409-16414
12. Henry, K. W., Yuan, X., Koszewski, N. J., Onda, H., Kwiatkowski, D. J., and Noonan, D. J. (1998) J. Biol. Chem. 273, 20535-20539
13. van Slegtenhorst, M., Nellist, M., Nagelkerken, B., Cheadle, J., Snell, R., van den Ouweland, A., Reuser, A., Sampson, J., Halley, D., and van der Sluijs, P. (1998) Hum. Mol. Genet. 7, 1053-1057
14. Plank, T. L., Yeung, R. S., and Henske, E. P. (1998) Cancer Res. 58, 4766-4770
15. Xiao, G., Shoarinejad, F., Jin, F., Golemis, E. A., and Yeung, R. S. (1997) J. Biol. Chem. 272, 6097-6100
16. Lamb, R. F., Roy, C., Diefenbach, T. J., Vinters, H. V., Johnson, M. W., Jay, D. G., and Hall, A. (2000) Nat. Cell Biol. 2, 281-287
17. Kamps, M. P., and Sefton, B. M. (1989) Anal. Biochem. 176, 22-27
18. Grangeasse, C., Riberty, M., Vaganay, E., and Duclos, B. (1999) Biotechniques 27, 62-64
19. MacKintosh, C., Garton, A. J., McDonnell, A., Barford, D., Cohen, P. T. W., Tonks, N. K., and Cohen, P. (1996) FEBS Lett. 397, 225-238
20. Aberle, H., Bauer, A., Stappert, J., Kispert, A., and Kemler. R. (1997) EMBO J. 16, 3797-3804
21. Deleted in proof
22. Hodges, A. K., Maynard, J., Parry, L., DeClue, J. E., Cheadle, J., and Sampson, J. (2000) Am. J. Hum. Genet. 67, 404 (abstr.)