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Volumn 169, Issue 4, 2013, Pages 391-400

Molecular and functional properties of densely and sparsely granulated GH-producing pituitary adenomas

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM CHANNEL; CALCIUM ION; CYCLIC AMP; GROWTH HORMONE; PROLACTIN; SOMATOSTATIN RECEPTOR 1; SOMATOSTATIN RECEPTOR 2; SOMATOSTATIN RECEPTOR 3; SOMATOSTATIN RECEPTOR 4; SOMATOSTATIN RECEPTOR 5; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR ZAC1; UNCLASSIFIED DRUG; VOLTAGE SENSITIVE CALCIUM CHANNEL;

EID: 84884878045     PISSN: 08044643     EISSN: 1479683X     Source Type: Journal    
DOI: 10.1530/EJE-13-0134     Document Type: Article
Times cited : (63)

References (60)
  • 1
    • 0036831826 scopus 로고    scopus 로고
    • The pathogenesis of pituitary tumours
    • DOI 10.1038/nrc926
    • Asa SL & Ezzat S. The pathogenesis of pituitary tumours. Nature Reviews. Cancer 2002 2 836-849. (doi:10.1038/nrc926) (Pubitemid 37328902)
    • (2002) Nature Reviews Cancer , vol.2 , Issue.11 , pp. 836-849
    • Asa, S.L.1    Ezzat, S.2
  • 2
    • 0033139646 scopus 로고    scopus 로고
    • Molecular pathogenesis of acromegaly
    • (doi:10.1023/A:1009917920589)
    • Drange MR & Melmed S. Molecular pathogenesis of acromegaly. Pituitary 1999 2 43-50. (doi:10.1023/A:1009917920589)
    • (1999) Pituitary , vol.2 , pp. 43-50
    • Drange, M.R.1    Melmed, S.2
  • 3
    • 34547774220 scopus 로고    scopus 로고
    • Susceptibility to pituitary neoplasia related to MEN-1, CDKN1B and AIP mutations: An update
    • DOI 10.1093/hmg/ddm036, Cancer Genetics
    • Karhu A & Aaltonen LA. Susceptibility to pituitary neoplasia related to MEN-1, CDKN1B and AIP mutations: an update. Human Molecular Genetics 2007 16 R73-R79. (doi:10.1093/hmg/ddm036) (Pubitemid 47241845)
    • (2007) Human Molecular Genetics , vol.16 , Issue.R1
    • Karhu, A.1    Aaltonen, L.A.2
  • 4
    • 0024404145 scopus 로고
    • GTPase inhibiting mutations activate the α chain of G(s) and stimulate adenylyl cyclase in human pituitary tumours
    • DOI 10.1038/340692a0
    • Landis CA, Masters SB, Spada A, Pace AM, Bourne HR & Vallar L. GTPase inhibiting mutations activate the a chain of Gs and stimulate adenylyl cyclase in human pituitary tumours. Nature 1989 340 692-696. (doi:10.1038/340692a0) (Pubitemid 19214389)
    • (1989) Nature , vol.340 , Issue.6236 , pp. 692-696
    • Landis, C.A.1    Masters, S.B.2    Spada, A.3    Pace, A.M.4    Bourne, H.R.5    Vallar, L.6
  • 7
    • 33750062886 scopus 로고    scopus 로고
    • Pathology of acromegaly
    • DOI 10.1159/000095524
    • Horvath E & Kovacs K. Pathology of acromegaly. Neuroendocrinology 2006 83 161-165. (doi:10.1159/000095524) (Pubitemid 44578868)
    • (2006) Neuroendocrinology , vol.83 , Issue.3-4 , pp. 161-165
    • Horvath, E.1    Kovacs, K.2
  • 8
    • 55249120008 scopus 로고    scopus 로고
    • Clinicopathological features of growth hormone-producing pituitary adenomas: Difference among various types defined by cytokeratin distribution pattern including a transitional form
    • (doi:10.1007/s12022-008-9029-z)
    • Obari A, Sano T, Ohyama K, Kudo E, Qian ZR, Yoneda A, Rayhan N, Mustafizur Rahman M & Yamada S. Clinicopathological features of growth hormone-producing pituitary adenomas: difference among various types defined by cytokeratin distribution pattern including a transitional form. Endocrine Pathology 2008 19 82-91. (doi:10.1007/s12022-008-9029-z)
    • (2008) Endocrine Pathology , vol.19 , pp. 82-91
    • Obari, A.1    Sano, T.2    Ohyama, K.3    Kudo, E.4    Qian, Z.R.5    Yoneda, A.6    Rayhan, N.7    Mustafizur Rahman, M.8    Yamada, S.9
  • 10
    • 27544470454 scopus 로고    scopus 로고
    • The implication of somatotroph adenoma phenotype to somatostatin analog responsiveness in acromegaly
    • DOI 10.1210/jc.2005-0998
    • Bhayana S, Booth GL, Asa SL, Kovacs K & Ezzat S. The implication of somatotroph adenoma phenotype to somatostatin analog responsiveness in acromegaly. Journal of Clinical Endocrinology and Metabolism 2005 90 6290-6295. (doi:10.1210/jc.2005-0998) (Pubitemid 41606558)
    • (2005) Journal of Clinical Endocrinology and Metabolism , vol.90 , Issue.11 , pp. 6290-6295
    • Bhayana, S.1    Booth, G.L.2    Asa, S.L.3    Kovacs, K.4    Ezzat, S.5
  • 11
    • 83455200225 scopus 로고    scopus 로고
    • Adenoma granulation pattern correlates with clinical variables and effect of somatostatin analogue treatment in a large series of patients with acromegaly
    • (doi:10.1111/j.1365-2265.2011.04163.x)
    • Fougner SL, Casar-Borota O, Heck A, Berg JP & Bollerslev J. Adenoma granulation pattern correlates with clinical variables and effect of somatostatin analogue treatment in a large series of patients with acromegaly. Clinical Endocrinology 2012 76 96-102. (doi:10.1111/j.1365-2265.2011.04163.x)
    • (2012) Clinical Endocrinology , vol.76 , pp. 96-102
    • Fougner, S.L.1    Casar-Borota, O.2    Heck, A.3    Berg, J.P.4    Bollerslev, J.5
  • 12
    • 84875156034 scopus 로고    scopus 로고
    • Granulation pattern, but not GSP or GHR mutation, is associated with clinical characteristics in somatostatin-naive patients with somatotroph adenomas
    • (doi:10.1530/EJE-12-0864)
    • Larkin S, Reddy R, Karavitaki N, Cudlip S, Wass J & Ansorge O. Granulation pattern, but not GSP or GHR mutation, is associated with clinical characteristics in somatostatin-naive patients with somatotroph adenomas. European Journal of Endocrinology 2013 168 491-499. (doi:10.1530/EJE-12-0864)
    • (2013) European Journal of Endocrinology , vol.168 , pp. 491-499
    • Larkin, S.1    Reddy, R.2    Karavitaki, N.3    Cudlip, S.4    Wass, J.5    Ansorge, O.6
  • 13
    • 84888200385 scopus 로고    scopus 로고
    • Growth hormone granulation pattern and somatostatin receptor subtype 2A correlate with postoperative somatostatin receptor ligand response in acromegaly: A large single center experience
    • In press. (doi:10.1007/s11102-012-0445-1)
    • Brzana J, Yedinak CG, Gultekin SH, Delashaw JB & Fleseriu M. Growth hormone granulation pattern and somatostatin receptor subtype 2A correlate with postoperative somatostatin receptor ligand response in acromegaly: a large single center experience. Pituitary 2013. In press. (doi:10.1007/s11102-012- 0445-1)
    • (2013) Pituitary
    • Brzana, J.1    Yedinak, C.G.2    Gultekin, S.H.3    Delashaw, J.B.4    Fleseriu, M.5
  • 15
    • 34547821490 scopus 로고    scopus 로고
    • Molecular genetics of the cAMP-dependent protein kinase pathway and of sporadic pituitary tumorigenesis
    • DOI 10.1093/hmg/ddm019, Cancer Genetics
    • Boikos SA & Stratakis CA. Molecular genetics of the cAMPdependent protein kinase pathway and of sporadic pituitary tumorigenesis. Human Molecular Genetics 2007 16 R80-R87. (doi:10.1093/hmg/ddm019) (Pubitemid 47241846)
    • (2007) Human Molecular Genetics , vol.16 , Issue.R1
    • Boikos, S.A.1    Stratakis, C.A.2
  • 17
    • 80054866128 scopus 로고    scopus 로고
    • The ghrelin/GOAT/GHS-R system and energy metabolism
    • (doi:10.1007/s11154-011-9169-1)
    • Lim CT, Kola B & Korbonits M. The ghrelin/GOAT/GHS-R system and energy metabolism. Reviews in Endocrine & Metabolic Disorders 2011 12 173-186. (doi:10.1007/s11154-011-9169-1)
    • (2011) Reviews in Endocrine & Metabolic Disorders , vol.12 , pp. 173-186
    • Lim, C.T.1    Kola, B.2    Korbonits, M.3
  • 18
    • 0023924577 scopus 로고
    • Potassium depolarization elevates cytosolic free calcium concentration in rat anterior pituitary cells through 1,4-dihydropyridine-sensitive, omega-conotoxin-insensitive calcium channels
    • (doi:10.1210/endo-122-6-2764)
    • Meier K, Knepel W & Schofl C. Potassium depolarization elevates cytosolic free calcium concentration in rat anterior pituitary cells through 1,4-dihydropyridine-sensitive, omega-conotoxin-insensitive calcium channels. Endocrinology 1988 122 2764-2770. (doi:10.1210/endo-122-6-2764)
    • (1988) Endocrinology , vol.122 , pp. 2764-2770
    • Meier, K.1    Knepel, W.2    Schofl, C.3
  • 19
    • 0023503039 scopus 로고
    • GRF elevates cytosolic free calcium concentration in rat anterior pituitary cells
    • Schofl C, Sandow J & KnepelW. GRF elevates cytosolic free calcium concentration in rat anterior pituitary cells. American Journal of Physiology 1987 253 E591-E594.
    • (1987) American Journal of Physiology , vol.253
    • Schofl, C.1    Sandow, J.2    Knepel, W.3
  • 20
    • 0034824420 scopus 로고    scopus 로고
    • Regulation of PIT-1 expression by ghrelin and GHRP-6 through the GH secretagogue receptor
    • DOI 10.1210/me.15.9.1484
    • Garcia A, Alvarez CV, Smith RG & Dieguez C. Regulation of Pit-1 expression by ghrelin and GHRP-6 through the GH secretagogue receptor. Molecular Endocrinology 2001 15 1484-1495. (doi:10. 1210/me.15.9.1484) (Pubitemid 32826401)
    • (2001) Molecular Endocrinology , vol.15 , Issue.9 , pp. 1484-1495
    • Garcia, A.1    Alvarez, C.V.2    Smith, R.G.3    Dieguez, C.4
  • 21
    • 0344659810 scopus 로고
    • Hyperpolarization of the membrane potential caused by somatostatin in dissociated human pituitary adenoma cells that secrete growth hormone
    • DOI 10.1073/pnas.83.16.6198
    • Yamashita N, Shibuya N & Ogata E. Hyperpolarization of the membrane potential caused by somatostatin in dissociated human pituitary adenoma cells that secrete growth hormone. PNAS 1986 83 6198-6202. (doi:10.1073/pnas.83.16. 6198) (Pubitemid 16000680)
    • (1986) Proceedings of the National Academy of Sciences of the United States of America , vol.83 , Issue.16 , pp. 6198-6202
    • Yamashita, N.1    Shibuya, N.2    Ogata, E.3
  • 22
    • 0033306790 scopus 로고    scopus 로고
    • Heterozygous gsp mutation renders ion channels of human somatotroph adenoma cells unresponsive to growth hormone-releasing hormone
    • Yasufuku-Takano J, Takano K, Takei T, Fukumoto S, Teramoto A, Takakura K, Yamashita N & Fujita T. Heterozygous gsp mutation renders ion channels of human somatotroph adenoma cells unresponsive to growth hormone-releasing hormone. Endocrinology 1999 140 2018-2026. (doi:10.1210/en.140.5.2018) (Pubitemid 30636438)
    • (1999) Endocrinology , vol.140 , Issue.5 , pp. 2018-2026
    • Yasufuku-Takano, J.1    Takano, K.2    Takei, T.3    Fukumoto, S.4    Teramoto, A.5    Takakura, K.6    Yamashita, N.7    Fujita, T.8
  • 23
    • 0020593740 scopus 로고
    • Stimulation of adenosine 3',5'-monophosphate production by growth hormone-releasing factor and its inhibition by somatostatin in anterior pituitary cells in vitro
    • Bilezikjian LM & Vale WW. Stimulation of adenosine 30,50-monophosphate production by growth hormone-releasing factor and its inhibition by somatostatin in anterior pituitary cells in vitro. Endocrinology 1983 113 1726-1731. (doi:10.1210/endo-113-5-1726) (Pubitemid 13023813)
    • (1983) Endocrinology , vol.113 , Issue.5 , pp. 1726-1731
    • Bilezikjian, L.M.1    Vale, W.W.2
  • 25
    • 0031032953 scopus 로고    scopus 로고
    • Intracellular calcium ion responses to somatostatin in cells from human somatotroph adenomas
    • Chen ZP, Xu S, Lightman SL, Hall L & Levy A. Intracellular calcium ion responses to somatostatin in cells from human somatotroph adenomas. Clinical Endocrinology 1997 46 45-53. (doi:10.1046/j.1365-2265.1997.d01-1739.x) (Pubitemid 27072845)
    • (1997) Clinical Endocrinology , vol.46 , Issue.1 , pp. 45-53
    • Chen, Z.-P.1    Xu, S.2    Lightman, S.L.3    Hall, L.4    Levy, A.5
  • 26
    • 32944477371 scopus 로고    scopus 로고
    • Octreotide, a somatostatin analogue, mediates its antiproliferative action in pituitary tumor cells by altering phosphatidylinositol 3-kinase signaling and inducing Zac1 expression
    • DOI 10.1158/0008-5472.CAN-05-1189
    • Theodoropoulou M, Zhang J, Laupheimer S, Paez-Pereda M, Erneux C, Florio T, Pagotto U & Stalla GK. Octreotide, a somatostatin analogue, mediates its antiproliferative action in pituitary tumor cells by altering phosphatidylinositol 3-kinase signaling and inducing Zac1 expression. Cancer Research 2006 66 1576-1582. (doi:10.1158/0008-5472.CAN-05-1189) (Pubitemid 43259940)
    • (2006) Cancer Research , vol.66 , Issue.3 , pp. 1576-1582
    • Theodoropoulou, M.1    Zhang, J.2    Laupheimer, S.3    Paez-Pereda, M.4    Erneux, C.5    Florio, T.6    Pagotto, U.7    Stalla, G.K.8
  • 30
    • 84861312469 scopus 로고    scopus 로고
    • Identification of critical residues involved in ligand binding and G protein signaling in human somatostatin receptor subtype 2
    • (doi:10.1210/en.2011-1662)
    • Parry JJ, Chen R, Andrews R, Lears KA & Rogers BE. Identification of critical residues involved in ligand binding and G protein signaling in human somatostatin receptor subtype 2. Endocrinology 2012 153 2747-2755. (doi:10.1210/en.2011-1662)
    • (2012) Endocrinology , vol.153 , pp. 2747-2755
    • Parry, J.J.1    Chen, R.2    Andrews, R.3    Lears, K.A.4    Rogers, B.E.5
  • 35
    • 0036135375 scopus 로고    scopus 로고
    • Identification of somatostatin receptor subtypes 1, 2A, 3, and 5 in neuroendocrine tumours with subtype specific antibodies
    • DOI 10.1136/gut.0500052..
    • Kulaksiz H, Eissele R, Rossler D, Schulz S, Hollt V, Cetin Y & Arnold R. Identification of somatostatin receptor subtypes 1, 2A, 3, and 5 in neuroendocrine tumours with subtype specific antibodies. Gut 2002 50 52-60. (doi:10.1136/gut.50.1.52) (Pubitemid 34028303)
    • (2002) Gut , vol.50 , Issue.1 , pp. 52-60
    • Kulaksiz, H.1    Eissele, R.2    Rossler, D.3    Schulz, S.4    Hollt, V.5    Cetin, Y.6    Arnold, R.7
  • 36
    • 0032908805 scopus 로고    scopus 로고
    • Subtype-selective expression of the five somatostatin receptors (hSSTR1- 5) in human pancreatic islet cells: A quantitative double-label immunohistochemical analysis
    • DOI 10.2337/diabetes.48.1.77
    • Kumar U, Sasi R, Suresh S, Patel A, Thangaraju M, Metrakos P, Patel SC & Patel YC. Subtype-selective expression of the five somatostatin receptors (hSSTR1-5) in human pancreatic islet cells: a quantitative double-label immunohistochemical analysis. Diabetes 1999 48 77-85. (doi:10.2337/diabetes.48. 1.77) (Pubitemid 29019355)
    • (1999) Diabetes , vol.48 , Issue.1 , pp. 77-85
    • Kumar, U.1    Sasi, R.2    Suresh, S.3    Patel, A.4    Thangaraju, M.5    Metrakos, P.6    Patel, S.C.7    Patel, Y.C.8
  • 38
    • 43949088527 scopus 로고    scopus 로고
    • Immunohistochemical localization of somatostatin receptor subtypes in benign and malignant adrenal tumours
    • DOI 10.1111/j.1365-2265.2007.03124.x
    • Unger N, Serdiuk I, Sheu SY, Walz MK, Schulz S, Saeger W, Schmid KW, Mann K & Petersenn S. Immunohistochemical localization of somatostatin receptor subtypes in benign and malignant adrenal tumours. Clinical Endocrinology 2008 68 850-857. (doi:10.1111/j.1365-2265.2007.03124.x) (Pubitemid 351703940)
    • (2008) Clinical Endocrinology , vol.68 , Issue.6 , pp. 850-857
    • Unger, N.1    Serdiuk, I.2    Sheu, S.-Y.3    Walz, M.K.4    Schulz, S.5    Saeger, W.6    Schmid, K.W.7    Mann, K.8    Petersenn, S.9
  • 40
    • 0035845567 scopus 로고    scopus 로고
    • Distinct effects of cAMP and mitogenic signals on CREB-binding protein recruitment impart specificity to target gene activation via CREB
    • DOI 10.1073/pnas.191152098
    • Mayr BM, Canettieri G & Montminy MR. Distinct effects of cAMP and mitogenic signals on CREB-binding protein recruitment impart specificity to target gene activation via CREB. PNAS 2001 98 10936-10941. (doi:10.1073/pnas. 191152098) (Pubitemid 32878722)
    • (2001) Proceedings of the National Academy of Sciences of the United States of America , vol.98 , Issue.19 , pp. 10936-10941
    • Mayr, B.M.1    Canettieri, G.2    Montminy, M.R.3
  • 42
    • 1542356381 scopus 로고    scopus 로고
    • Standardized determination of real-time PCR efficiency from a single reaction set-up
    • (doi:10.1093/nar/gng122)
    • Tichopad A, Dilger M, Schwarz G & Pfaffl MW. Standardized determination of real-time PCR efficiency from a single reaction set-up. Nucleic Acids Research 2003 31 e122. (doi:10.1093/nar/gng122)
    • (2003) Nucleic Acids Research , vol.31
    • Tichopad, A.1    Dilger, M.2    Schwarz, G.3    Pfaffl, M.W.4
  • 43
    • 0035430282 scopus 로고    scopus 로고
    • Transcriptional regulation by the phosphorylation-dependent factor creb
    • DOI 10.1038/35085068
    • Mayr B & Montminy M. Transcriptional regulation by the phosphorylation-dependent factor CREB. Nature Reviews. Molecular Cell Biology 2001 2 599-609. (doi:10.1038/35085068) (Pubitemid 33674011)
    • (2001) Nature Reviews Molecular Cell Biology , vol.2 , Issue.8 , pp. 599-609
    • Mayr, B.1    Montminy, M.2
  • 46
    • 79960415078 scopus 로고    scopus 로고
    • Differential expression of somatostatin receptor subtype-related genes and proteins in non-functioning and functioning adrenal cortex adenomas
    • Pisarek H, Krupinski R, Kubiak R, Borkowska E, Pawlikowski M & Winczyk K. Differential expression of somatostatin receptor subtype-related genes and proteins in non-functioning and functioning adrenal cortex adenomas. Molecular Medicine Reports 2011 4 963-969.
    • (2011) Molecular Medicine Reports , vol.4 , pp. 963-969
    • Pisarek, H.1    Krupinski, R.2    Kubiak, R.3    Borkowska, E.4    Pawlikowski, M.5    Winczyk, K.6
  • 47
    • 21644450897 scopus 로고    scopus 로고
    • Somatostatin receptors in primary human breast cancer: Quantitative analysis of mRNA for subtypes 1-5 and correlation with receptor protein expression and tumor pathology
    • DOI 10.1007/s10549-005-2414-0
    • Kumar U, Grigorakis SI, Watt HL, Sasi R, Snell L, Watson P & Chaudhari S. Somatostatin receptors in primary human breast cancer: quantitative analysis of mRNA for subtypes 1-5 and correlation with receptor protein expression and tumor pathology. Breast Cancer Research and Treatment 2005 92 175-186. (doi:10.1007/s10549-005-2414-0) (Pubitemid 40933583)
    • (2005) Breast Cancer Research and Treatment , vol.92 , Issue.2 , pp. 175-186
    • Kumar, U.1    Grigorakis, S.I.2    Watt, H.L.3    Sasi, R.4    Snell, L.5    Watson, P.6    Chaudhari, S.7
  • 48
    • 68849127827 scopus 로고    scopus 로고
    • Expression of somatostatin receptor subtypes in human thyroid tumors: The immunohistochemical and molecular biology (RT-PCR) investigation
    • (doi:10.1186/1756-6614-2-1)
    • Pisarek H, Stepien T, Kubiak R, Borkowska E & Pawlikowski M. Expression of somatostatin receptor subtypes in human thyroid tumors: the immunohistochemical and molecular biology (RT-PCR) investigation. Thyroid Research 2009 2 1. (doi:10.1186/1756-6614-2-1)
    • (2009) Thyroid Research , vol.2 , pp. 1
    • Pisarek, H.1    Stepien, T.2    Kubiak, R.3    Borkowska, E.4    Pawlikowski, M.5
  • 49
    • 34249659606 scopus 로고    scopus 로고
    • Intermediate filaments: A role in epithelial polarity
    • DOI 10.1016/j.yexcr.2007.02.030, PII S0014482707000869
    • Oriolo AS, Wald FA, Ramsauer VP & Salas PJ. Intermediate filaments: a role in epithelial polarity. Experimental Cell Research 2007 313 2255-2264. (doi:10.1016/j.yexcr.2007.02.030) (Pubitemid 46842972)
    • (2007) Experimental Cell Research , vol.313 , Issue.10 , pp. 2255-2264
    • Oriolo, A.S.1    Wald, F.A.2    Ramsauer, V.P.3    Salas, P.J.I.4
  • 51
    • 0030690974 scopus 로고    scopus 로고
    • Somatostatin receptor (SSTR) subtype-selective analogues differentially suppress in vitro growth hormone and prolactin in human pituitary adenomas: Novel potential therapy for functional pituitary tumors
    • Shimon I, Yan X, Taylor JE, Weiss MH, Culler MD & Melmed S. Somatostatin receptor (SSTR) subtype-selective analogues differentially suppress in vitro growth hormone and prolactin in human pituitary adenomas. Novel potential therapy for functional pituitary tumors. Journal of Clinical Investigation 1997 100 2386-2392. (doi:10.1172/JCI119779) (Pubitemid 27500164)
    • (1997) Journal of Clinical Investigation , vol.100 , Issue.9 , pp. 2386-2392
    • Shimon, I.1    Yan, X.2    Taylor, J.E.3    Weiss, M.H.4    Culler, M.D.5    Melmed, S.6
  • 52
    • 2642535412 scopus 로고    scopus 로고
    • Regulation and function of somatostatin receptors
    • DOI 10.1111/j.1471-4159.2004.02402.x
    • Olias G, Viollet C, Kusserow H, Epelbaum J & Meyerhof W. Regulation and function of somatostatin receptors. Journal of Neurochemistry 2004 89 1057-1091. (doi:10.1111/j.1471-4159.2004.02402.x) (Pubitemid 38720193)
    • (2004) Journal of Neurochemistry , vol.89 , Issue.5 , pp. 1057-1091
    • Olias, G.1    Viollet, C.2    Kusserow, H.3    Epelbaum, J.4    Meyerhof, W.5
  • 53
    • 0033322617 scopus 로고    scopus 로고
    • Impact of gsp oncogene on the expression of genes coding for G(s)α, Pit-1, G(i)2α, and somatostatin receptor 2 in human somatotroph adenomas: Involvement in octreotide sensitivity
    • Barlier A, Pellegrini-Bouiller I, Gunz G, Zamora AJ, Jaquet P & Enjalbert A. Impact of gsp oncogene on the expression of genes coding for Gsa, Pit-1, Gi2a, and somatostatin receptor 2 in human somatotroph adenomas: involvement in octreotide sensitivity. Journal of Clinical Endocrinology and Metabolism 1999 84 2759-2765. (doi:10.1210/jc.84.8.2759) (Pubitemid 30642008)
    • (1999) Journal of Clinical Endocrinology and Metabolism , vol.84 , Issue.8 , pp. 2759-2765
    • Barlier, A.1    Pellegrini-Bouiller, I.2    Gunz, G.3    Zamora, A.J.4    Jaquet, P.5    Enjalbert, A.6
  • 54
    • 17744378733 scopus 로고    scopus 로고
    • Human somatostatin receptor subtypes in acromegaly: Distinct patterns of messenger ribonucleic acid expression and hormone suppression identify different tumoral phenotypes
    • DOI 10.1210/jc.85.2.781
    • Jaquet P, Saveanu A, Gunz G, Fina F, Zamora AJ, Grino M, Culler MD, Moreau JP, Enjalbert A & Ouafik LH. Human somatostatin receptor subtypes in acromegaly: distinct patterns of messenger ribonucleic acid expression and hormone suppression identify different tumoral phenotypes. Journal of Clinical Endocrinology and Metabolism 2000 85 781-792. (doi:10.1210/jc.85.2.781) (Pubitemid 32273669)
    • (2000) Journal of Clinical Endocrinology and Metabolism , vol.85 , Issue.2 , pp. 781-792
    • Jaquet, P.1    Saveanu, A.2    Gunz, G.3    Fina, F.4    Zamora, A.J.5    Grino, M.6    Culler, M.D.7    Moreau, J.P.8    Enjalbert, A.9    Ouafik, L'H.10
  • 55
    • 42149145552 scopus 로고    scopus 로고
    • Correlation of in vitro and in vivo somatotropic adenoma responsiveness to somatostatin analogs and dopamine agonists with immunohistochemical evaluation of somatostatin and dopamine receptors and electron microscopy
    • DOI 10.1210/jc.2007-1358
    • Ferone D, de HerderWW, Pivonello R, Kros JM, van Koetsveld PM, de Jong T, Minuto F, Colao A, Lamberts SW & Hofland LJ. Correlation of in vitro and in vivo somatotropic adenoma responsiveness to somatostatin analogs and dopamine agonists with immunohistochemical evaluation of somatostatin and dopamine receptors and electron microscopy. Journal of Clinical Endocrinology and Metabolism 2008 93 1412-1417. (doi:10.1210/jc.2007-1358) (Pubitemid 351522738)
    • (2008) Journal of Clinical Endocrinology and Metabolism , vol.93 , Issue.4 , pp. 1412-1417
    • Ferone, D.1    De Herder, W.W.2    Pivonello, R.3    Kros, J.M.4    Van Koetsveld, P.M.5    De Jong, T.6    Minuto, F.7    Colao, A.8    Lamberts, S.W.J.9    Hofland, L.J.10
  • 56
    • 39149098829 scopus 로고    scopus 로고
    • The clinical response to somatostatin analogues in acromegaly correlates to the somatostatin receptor subtype 2a protein expression of the adenoma
    • DOI 10.1111/j.1365-2265.2007.03065.x
    • Fougner SL, Borota OC, Berg JP, Hald JK, Ramm-Pettersen J & Bollerslev J. The clinical response to somatostatin analogues in acromegaly correlates to the somatostatin receptor subtype 2a protein expression of the adenoma. Clinical Endocrinology 2008 68 458-465. (doi:10.1111/j.1365-2265.2007. 03065.x) (Pubitemid 351257867)
    • (2008) Clinical Endocrinology , vol.68 , Issue.3 , pp. 458-465
    • Fougner, S.L.1    Borota, O.C.2    Berg, J.P.3    Hald, J.K.4    Ramm-Pettersen, J.5    Bollerslev, J.6
  • 58
    • 84898816902 scopus 로고    scopus 로고
    • Long-term efficacy and safety of subcutaneous pasireotide in acromegaly: Results from an open-ended, multicenter, phase II extension study
    • In press. (doi:10.1007/s11102-013-0478-0)
    • Petersenn S, Farrall AJ, Block C, Melmed S, Schopohl J, Caron P, Cuneo R, Kleinberg D, Colao A, Ruffin M et al. Long-term efficacy and safety of subcutaneous pasireotide in acromegaly: results from an open-ended, multicenter, phase II extension study. Pituitary 2013. In press. (doi:10.1007/s11102-013- 0478-0)
    • (2013) Pituitary
    • Petersenn, S.1    Farrall, A.J.2    Block, C.3    Melmed, S.4    Schopohl, J.5    Caron, P.6    Cuneo, R.7    Kleinberg, D.8    Colao, A.9    Ruffin, M.10


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