Intracellular calcium ion responses to somatostatin in cells from human somatotroph adenomas

Clinical Endocrinology

Volumn 46, Issue 1, 1997, Pages 45-53

  Chen, Zhen Ping ^a,b   Xu, Su ^a   Lightman, Stafford L ^a   Hall, Len ^a   Levy, Andrew ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH HORMONE; GROWTH HORMONE RELEASING FACTOR; PERTUSSIS TOXIN; SOMATOSTATIN; SOMATOSTATIN RECEPTOR;

ACROMEGALY; ADULT; AGED; ARTICLE; CALCIUM CELL LEVEL; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; HYPOPHYSIS ADENOMA; MALE; PRIORITY JOURNAL;

EID: 0031032953     PISSN: 03000664     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2265.1997.d01-1739.x     Document Type: Article

References (46)

1. Carlson, H.E., Mariz, I.K. & Daughaday, W.H. (1974) Thyrotropin-releasing hormone stimulation and somatostatin inhibition of growth hormone secretion. Endocrinology, 94, 1709-1713.
2. Caron, P., Cogne, M., Catus, F. & Bayard, F. (1993) Intramuscular (IM) injections of BIM 23014 in acromegalic patients previously treated by continuous subcutaneous infusion of somatostatin 201-995 (SMS). 75th Annual Meeting of the Endocrine Society USA, pp. 68 (abs.).
3. Chen, Z.P., Levy, A. & Lightman, S.L. (1994) Activation of specific ATP receptors induces a rapid increase in intracellular calcium ions in rat hypothalamic neurons. Brain Research, 641, 249-256.
4. Cowan, J.S., Moor, B., Chow, A. & Kraicer, J. (1983) Characteristics of the post-somatostatin rebound in growth hormone secretion from perifused somatotrophs. Endocrinology, 113, 1056-1061.
5. Dufy-Barbe, L., Bresson, L., Sartor, P., Odessa, M.F. & Dufy, B. (1992) Calcium homeostasis in growth hormone(GH)-secreting adenoma cells: effect of GH-releasing factor. Endocrinology, 131, 1436-1444.
6. Ezzat, S., Snyder, P.J., Young, W.F., Boyajy, L.D., Newman, C., Klibanski, A., Molitch, M.E., Boyd, A.E., Sheeler, L., Cook, D.M., Malarkey, W.B., Jackson, I., Vance, M.L., Thorner, M.O., Barkan, A., Frohaman, L.A. & Melmed, S. (1992) Octreotide treatment of acromegaly. A randomized, multicenter study. Annals of Internal Medicine, 117, 711-718.
7. 2+ channels. Journal of Clinical Endocrinology and Metabolism, 76, 1265-1270.
8. 2+ indicators with greatly improved fluorescence properties. Journal of Biological Chemistry, 260, 3440-3450.
9. Holl, R.W., Thorner, M.O. & Leong, D.A. (1988) Intracellular calcium concentration and growth hormone secretion in individual somatotrophic cells: effects of growth hormone-releasing factor and somatostatin. Endocrinology, 122, 2927-2932.
10. Kleuss, C., Hescheler, J., Ewel, C., Rosenthal, W., Schultz, G. & Wittig, B. (1991) Assignment of G-protein subtypes to specific receptors inducing inhibition of calcium currents. Nature, 353, 43-48.
11. Koch, B.D., Dorflinger, L.J. & Schonbrunn, A. (1985) Pertussis toxin blocks both cyclic AMP-mediated and cyclic AMP-independent actions of somatostatin: evidence for coupling of Ni to decrease in intracellular free calcium. Journal of Biological Chemistry, 260, 13138-13145.
12. Kraicer, J., Cowan, J.S., Sheppard, M.S., Lussier, B. & Moor, B.C. (1986) Effect of somatostatin withdrawal and growth hormone (GH)-releasing factor on GH release in vitro: amount available for release after disinhibition. Endocrinology, 119, 2047-2051.
13. s protein. Journal of Clinical Endocrinology and Metabolism, 71, 1416-1420.
14. Levy, A., Hall, L., Yeudall, W.A. & Lightman, S.L. (1994) P53 gene mutations in pituitary adenomas: a rare event. Clinical Endocrinology, 41, 809-814.
15. Levy, A. & Lightman, S.L. (1988a) Quantitative in-situ hybridization histochemistry of anterior pituitary hormone mRNA species in human pituitary adenomas. Acta Endocrinologica (Copenhagen), 119, 397-404.
16. Levy, A. & Lightman, S.L. (1988b) Quantitative in-situ hybridization histochemistry studies on GH gene expression in acromegalic somatotrophs: effects of somatostatin, GH-releasing factor and cortisol. Journal of Molecular Endocrinology, 1, 19-26.
17. Levy, A. & Lightman, S.L. (1989) Relationship between somatostatin and growth hormone messenger ribonucleic acid in human pituitary adenomas; an in situ hybridization histochemistry study. Clinical Endocrinology, 32, 661-668.
18. Levy, A. & Lightman, S.L. (1991) In situ hybridization histochemistry. In Neuroendocrine Research Methods (ed. B. Greenstein), pp. 795-826. Harwood Academic Press, Reading.
19. 2+ responses to thyrotrophin-releasing hormone, gonadotrophin-releasing hormone and arginine vasopressin in pituitary corticotroph and somatotroph adenomas. Clinical Endocrinology, 33, 73-79.
20. Lewis, D.L., Weight, F.F. & Luini, A. (1986) A guanine nucleotide-binding protein mediates the inhibition of voltage-dependent calcium current by somatostatin in a pituitary cell line. Proceedings of National Academic Science USA, 83, 9035-9039.
21. Luini, A., Lewis, D., Guild, S., Schofield, G. & Weight, F. (1986) Somatostatin, an inhibitor of ACTH secretion, decreses cytosolic free calcium and voltage-dependent calcium current in a pituitary cell line. Journal of Neuroscience, 6, 3128-3132.
22. i. Endocrinology, 128, 570-582.
23. 2+ concentration and growth hormone (GH) release from purified rat somatotrophs. III. Mechanism of action of GH-releasing factor and somatostatin. Endocrinology, 128, 592-603.
24. 2+ influx. Endocrinology, 128, 583-591.
25. Luthin, D.R., Eppler, C.M. & Linden, J. (1993) Identification and quantification of Gi-type GTP-binding proteins that copurify with a pituitary somatostatin receptor. Journal of Biological Chemistry, 268, 5990-5996.
26. Mason, W.T., Hoyland, J., Rawlings, S. & Relf, G. (1990) Techniques and technology: dynamic video imaging of cellular fluorescence. In Methods in Neurosciences (ed. P. M. Conn), pp. 109-135. Academic Press, New York.
27. 2 and somatostatin on cyclic AMP accumulation in rat adenohypophysial cells in culture. Molecular and Cellular Endocrinology, 33, 255-264.
28. Narayanan, N., Lussier, B., French, M., Moor, B. & Kraicer, J. (1989) Growth hormone-releasing factor-sensitive adenylate cyclase system of purified somatotrophs: effect of guanine nucleotides, somatostatin, calcium, and magnesium. Endocrinology, 124, 484-495.
29. 2+ in rat somatotrophs. Endocrinology, 122, 1419-1425.
30. Rawlings, S.R., Hoyland, J. & Mason, W.T. (1991) Calcium homeostasis in bovine somatotrophs: calcium oscillations and calcium regulation by growth hormone-releasing hormone and somatostatin. Cell Calcium, 12, 403-414.
31. Reubi, J.C., Heitz, P.U. & Landolt, A.M. (1987) Visualization of somatostatin receptors and correlation with immunoreactive growth hormone and prolactin in human pituitary adenomas: evidence for different tumor subclasses. Journal of Clinical Endocrinology and Metabolism, 65, 65-73.
32. Reubi, J.C. & Landolt, A.M. (1989) The growth hormone responses to octreotide in acromegaly correlate with adenoma somatostatin receptor status. Journal of Clinical Endocrinology and Metabolism, 68, 844-850.
33. Richardson, S.B. & Twente, S. (1991) Pre-exposure of rat anterior pituitary cells to somatostatin enhances subsequent growth hormone secretion. Journal of Endocrinology, 128, 91-95.
34. Sassolas, G., Harris, A.G. & James-Deidier, A. (1990) Long term effect of incremental doses of the somatostatin analog SMS 201-995 in 58 acromegalic patients. French SMS 201-995 approximately equal to Acromegaly Study Group. Journal of Clinical Endocrinology and Metabolism, 71, 391-397.
35. Schöfl, C., Sandow, J. & Knepel, W. (1987) GRF elevates cytosolic calcium concentration in rat anterior pituitary cells. American Journal of Physiology, 253, E591-E594.
36. + conductance in freshly dispersed rat somatotrophs. Journal of Physiology (London), 441, 615-637.
37. Soya, H., Suzuki, M. & Kato, M. (1990) Somatostatin pretreatment facilitates GRF-induced GH release and increase in free calcium in pituitary cells. Biochemical and Biophysical Research Communications, 172, 276-281.
38. Spada, A., Arosio, M., Bochicchio, D., Bazzoni, N., Vallar, L., Bassetti, M. & Faglia, G. (1990) Clinical, biochemical, and morphological correlates in patients bearing growth hormone-secreting pituitary tumors without or with somatic mutation in the alpha-chain (αs) of the stimulatory regulatory protein of adenylyl cyclase (Gs). Journal of Clinical Endocrinology and Metabolism, 71, 1421-1426.
39. 2+ levels and adenylyl cyclase activity in human nonfuctioning pituitary adenomas. Journal of Clinical Endocrinology and Metabolism, 73, 913-918.
40. Strnad, J., Eppler, C.M., Corbett, M. & Hadcock, J.R. (1993) The rat SSTR2 Somatostatin receptor subtype is coupled to inhibition of cyclic AMP accumulation. Biochemical and Biophysical Research Communications, 191, 968-976.
41. Tauber, J.P., Babin, T., Tauber, M.T., Vigoni, F., Bonafe, A., Ducasse, M., Harris, A.G. & Bayard, F. (1989) Long term effects of continuous subcutaneous infusion of the somatostatin analog octreotide in the treatment of acromegaly. Journal of Clinical Endocrinology and Metabolism, 68, 917-924.
42. Vance, M.L. & Harris, A.G. (1991) Long-term treatment of 189 acromegalic patients with the somatostatin analog octreotide. Results of the International Multicenter Acromegaly Study Group. Archives of Internal Medicine, 151, 1573-1578.
43. Wass, J.A. (1990) Octreotide treatment of acromegaly. Hormone Research, 33 (Suppl 1), 1-6.
44. + channels through protein dephosphorylation. Nature, 351, 570-573.
45. Yamada, Y., Reisine, T., Law, S.F., Ihara, Y., Kubota, A., Kagimoto, S., Seino, M., Seino, Y., Bell, G.I. & Seino, S. (1992) Somatostatin receptors, an expanding gene family: cloning and functional characterization of human SSTR3, a protein coupled to adenylyl cyclase. Molecular Endocrinology, 6, 2136-2142.
46. Young III, W.S., Bonner, T.I. & Brann, M.R. (1986) Mesencephalic dopamine neurons regulate the ecpression of neuropeptide mRNAs in the rat forebrain. Proceedings of National Academic Science USA, 83, 9827-9831.