Synthesis, characterisation, and in vitro anticancer activity of curcumin analogues bearing pyrazole/pyrimidine ring targeting egfr tyrosine kinase

BioMed Research International

Volumn 2013, Issue , 2013, Pages

  Ahsan, Mohamed Jawed ^a   Khalilullah, Habibullah ^b   Yasmin, Sabina ^c   Jadav, Surender Singh ^c   Govindasamy, Jeyabalan ^b  

^a Maharishi Arvind Institute of Pharmacy   (India)

^b Alwar Pharmacy College   (India)

^c BIRLA INSTITUTE OF TECHNOLOGY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

3,5 BIS(4 HYDROXY 3 METHYLSTYRYL) 1H PYRAZOLE 1 YL(2 BROMOPHENYL)METHANONE; 3,5 BIS(4 HYDROXY 3 METHYLSTYRYL) 1H PYRAZOLE 1 YL(PHENYL)METHANONE; 3,5 BIS(4 HYDROXY 3 METHYLSTYRYL) N (2 CHLOROPHENYL) 1H PYRAZOLE 1 CARBOXAMIDE; 3,5 BIS(4 HYDROXY 3 METHYLSTYRYL) N (2 METHYLPHENYL) 1H PYRAZOLE 1 CARBOXAMIDE; 3,5 BIS(4 HYDROXY 3 METHYLSTYRYL) N (2,4 DIMETHYLPHENYL) 1H PYRAZOLE 1 CARBOXAMIDE; 3,5 BIS(4 HYDROXY 3 METHYLSTYRYL) N (2,6 DIMETHYLPHENYL) 1H PYRAZOLE 1 CARBOXAMIDE; 3,5 BIS(4 HYDROXY 3 METHYLSTYRYL) N (3 CHLORO 4 FLUOROPHENYL) 1H PYRAZOLE 1 CARBOXAMIDE; 3,5 BIS(4 HYDROXY 3 METHYLSTYRYL) N (4 BROMOPHENYL) 1H PYRAZOLE 1 CARBOXAMIDE; 3,5 BIS(4 HYDROXY 3 METHYLSTYRYL) N (4 CHLOROPHENYL) 1H PYRAZOLE 1 CARBOXAMIDE; 3,5 BIS(4 HYDROXY 3 METHYLSTYRYL) N (4 FLUOROPHENYL) 1H PYRAZOLE 1 CARBOXAMIDE; 3,5 BIS(4 HYDROXY 3 METHYLSTYRYL) N (4 METHYLPHENYL) 1H PYRAZOLE 1 CARBOXAMIDE; 4,4' ([2 IMINO 1,2 DIHYDROPYRIMIDINE 4,6 DIYL]DIETHENE 2,1 DIYL)BIS(2METHOXYPHENOL); 4,6 BIS(2[4 HYDROXY 3 METHOXPHENYL]ETHENYL)PYRIMIDINE 2(1H) THIONE; 4,6 BIS(4 HYDROXY 3 METHOXYSTYRYL)PYRIMIDINE 2(1H)ONE; CURCUMIN; EPIDERMAL GROWTH FACTOR RECEPTOR; UNCLASSIFIED DRUG; DRUG DERIVATIVE; EGFR PROTEIN, HUMAN; PROTEIN KINASE INHIBITOR; PYRAZOLE; PYRAZOLE DERIVATIVE; PYRIMIDINE; PYRIMIDINE DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BRAIN CANCER; BREAST CANCER; CANCER CELL CULTURE; CANCER INHIBITION; COLON CANCER; CONCENTRATION RESPONSE; CONTROLLED STUDY; CRYSTALLIZATION; DRUG ANALYSIS; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; KIDNEY CANCER; LEUKEMIA CELL LINE; LUNG NON SMALL CELL CANCER; MELANOMA; MOLECULAR DOCKING; OVARY CANCER; PROSTATE CANCER; BINDING SITE; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; METABOLISM; SYNTHESIS; TUMOR CELL LINE; X RAY CRYSTALLOGRAPHY;

BINDING SITES; CELL LINE, TUMOR; CRYSTALLOGRAPHY, X-RAY; CURCUMIN; HUMANS; MOLECULAR DOCKING SIMULATION; PROTEIN KINASE INHIBITORS; PYRAZOLES; PYRIMIDINES; RECEPTOR, EPIDERMAL GROWTH FACTOR;

EID: 84884847948     PISSN: 23146133     EISSN: 23146141     Source Type: Journal    
DOI: 10.1155/2013/239354     Document Type: Article

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