Molecular properties prediction and synthesis of novel pyrazoline carboxamide analogs as antitubercular agents

Anti-Infective Agents

Volumn 10, Issue 2, 2012, Pages 117-123

  Ahsan, Mohamed Jawed ^a,b   Samy, Jeyabalan Govinda ^a   Khalilullah, Habibullah ^a   Kirit, Choudhary R ^a   Soni, Savita ^a  

^a Alwar Pharmacy College   (India)

^b NIMS UNIVERSITY   (India)

Author keywords

Antitubercular agents; Claisen schmidt condensation; Lipinski "rule of five"; Lipophilicity; Molecular properties prediction; Pyrazolines

Indexed keywords

2 SUBSTITUTED 5,6 DIMETHOXY 2,3 DIHYDRO 1H INDENE1ONE DERIVATIVE; 3 (2 CHLOROPHENYL) N (4 METHYLPHENYL) 6,7 DIMETHOXY 3A,4 DIHYDRO 3H INDENO[1,2 C]PYRAZOLE 2 CARBOXAMIDE; 3 (3,4 DIMETHOXYPHENYL) N (2 CHLOROPHENYL) 6,7 DIMETHOXY 3A,4 DIHYDRO 3H INDENO[1,2 C]PYRAZOLE 2 CARBOXAMIDE; 3 (3,4 DIMETHOXYPHENYL) N (4 METHYLPHENYL) 6,7 DIMETHOXY 3A,4 DIHYDRO 3H INDENO[1,2 C]PYRAZOLE 2 CARBOXAMIDE; 3 (4 CYANOPHENYL) N (2 CHLOROPHENYL) 6,7 DIMETHOXY 3A,4 DIHYDRO 3H INDENO[1,2 C]PYRAZOLE 2 CARBOXAMIDE; 3 (4 CYANOPHENYL) N (4 METHYLPHENYL) 6,7 DIMETHOXY 3A,4 DIHYDRO 3H INDENO[1,2 C]PYRAZOLE 2 CARBOXAMIDE; 3 (4 FLUOROPHENYL) N (2 CHLOROPHENYL) 6,7 DIMETHOXY 3A,4 DIHYDRO 3H INDENO[1,2 C]PYRAZOLE 2 CARBOXAMIDE; 3 (4 FLUOROPHENYL) N (4 METHYLPHENYL) 6,7 DIMETHOXY 3A,4 DIHYDRO 3H INDENO[1,2 C]PYRAZOLE 2 CARBOXAMIDE; 3 (4 METHOXYPHENYL) N (2 CHLOROPHENYL) 6,7 DIMETHOXY 3A,4 DIHYDRO 3H INDENO[1,2 C]PYRAZOLE 2 CARBOXAMIDE; 3 (4 METHOXYPHENYL) N (4 METHYLPHENYL) 6,7 DIMETHOXY 3A,4 DIHYDRO 3H INDENO[1,2 C]PYRAZOLE 2 CARBOXAMIDE; 3 (PYRIDIN 4 YL) N (2 CHLOROPHENYL) 6,7 DIMETHOXY 3A,4 DIHYDRO 3H INDENO[1,2 C]PYRAZOLE 2 CARBOXAMIDE; 3 (PYRIDIN 4 YL) N (4 METHYLPHENYL) 6,7 DIMETHOXY 3A,4 DIHYDRO 3H INDENO[1,2 C]PYRAZOLE 2 CARBOXAMIDE; 3 PHENYL N (2 CHLOROPHENYL) 6,7 DIMETHOXY 3A,4 DIHYDRO 3H INDENO[1,2 C]PYRAZOLE 2 CARBOXAMIDE; 3 PHENYL N (4 METHYLPHENYL) 6,7 DIMETHOXY 3A,4 DIHYDRO 3H INDENO[1,2 C]PYRAZOLE 2 CARBOXAMIDE; ISONIAZID; N,3 BIS(2 CHLOROPHENYL) 6,7 DIMETHOXY 3A,4 DIHYDRO 3HINDENO[1,2 C]PYRAZOLE 2 CARBOXAMIDE; PYRAZOLINE CARBOXAMIDE DERIVATIVE; THIOACETAZONE; TUBERCULOSTATIC AGENT; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIBACTERIAL ACTIVITY; ARTICLE; BIOAVAILABILITY; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DRUG ABSORPTION; DRUG SOLUBILITY; DRUG STRUCTURE; DRUG SYNTHESIS; INFRARED SPECTROSCOPY; LIPOPHILICITY; MASS SPECTROMETRY; MINIMUM INHIBITORY CONCENTRATION; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PREDICTION; PROTON NUCLEAR MAGNETIC RESONANCE;

EID: 84885911419     PISSN: 22113525     EISSN: 22113533     Source Type: Journal    
DOI: 10.2174/2211362611208020117     Document Type: Article

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