POMA analyses as new efficient bioinformatics' platform to predict and optimise bioactivity of synthesized 3a,4-dihydro-3H-indeno[1,2-c]pyrazole-2- carboxamide/carbothioamide analogues

Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 23, 2012, Pages 7029-7035

  Ahsan, Mohamed Jawed ^a,b   Govindasamy, Jeyabalan ^a   Khalilullah, Habibullah ^a   Mohan, Govind ^b   Stables, James P ^c   Pannecouque, Christophe ^d   Clercq, Eric De ^d  

^a Alwar Pharmacy College   (India)

^b NIMS UNIVERSITY   (India)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

^d REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

Author keywords

Anti HIV; Antibacterial; Anticonvulsant; Antifungal; Petra Osiris Molinspiration ALOGPS 2.1 program; Pyrazolines; Tautomerism

Indexed keywords

3 (4 CHLOROPHENYL) N (4 FLUOROPHENYL) 6,7 DIMETHOXY 3A,4 DIHYDRO 3H INDENO[1,2 C]PYRAZOLE 2 CARBOXAMIDE; 3 (4 FLUOROPHENYL) 6,7 DIMETHOXY 3A,4 DIHYDRO 3H INDENO[1,2 C]PYRAZOLE 2 CARBOTHIOAMIDE; 3 (4 FLUOROPHENYL) N (4 CHLOROPHENYL) 6,7 DIMETHOXY 3A,4 DIHYDRO 3H INDENO[1,2 C]PYRAZOLE 2 CARBOXAMIDE; 3 (4 METHOXYPHENYL) 6,7 DIMETHOXY 3A,4 DIHYDRO 3H INDENO[1,2 C]PYRAZOLE 2 CARBOXAMIDE; AMIDE; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; ANTICONVULSIVE AGENT; ANTIFUNGAL AGENT; ANTIINFECTIVE AGENT; CIPROFLOXACIN; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ANTICONVULSANT ACTIVITY; ARTICLE; BIOINFORMATICS; LIPOPHILICITY; NONHUMAN; PHARMACOPHORE; SYNTHESIS;

AMIDES; ANIMALS; ANTI-BACTERIAL AGENTS; ANTI-HIV AGENTS; ANTICONVULSANTS; ANTIFUNGAL AGENTS; ASPERGILLUS NIGER; BACILLUS SUBTILIS; CANDIDA ALBICANS; CELL LINE; CELL SURVIVAL; COMPUTATIONAL BIOLOGY; ESCHERICHIA COLI; HIV-1; HIV-2; HUMANS; MICE; MICROBIAL SENSITIVITY TESTS; MOTOR ACTIVITY; PSEUDOMONAS AERUGINOSA; PYRAZOLES; STAPHYLOCOCCUS AUREUS; THIOAMIDES;

BACTERIA (MICROORGANISMS); OSIRIS;

EID: 84869080659     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2012.09.108     Document Type: Article

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