메뉴 건너뛰기




Volumn 113, Issue 7, 2013, Pages 891-901

Uncoupling protein 2 impacts endothelial phenotype via p53-Mediated control of mitochondrial dynamics

Author keywords

angiogenesis; endothelial function; endothelium; ischemia; mitochondria; mitochondrial uncoupling proteins; superoxides

Indexed keywords

PROTEIN P53; SUPEROXIDE; UNCOUPLING PROTEIN 2;

EID: 84884819273     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.113.301319     Document Type: Article
Times cited : (34)

References (57)
  • 1
    • 36949083936 scopus 로고
    • Coupling of phosphorylation to electron and hydrogen transfer by a chemi-osmotic type of mechanism
    • Mitchell P. Coupling of phosphorylation to electron and hydrogen transfer by a chemi-osmotic type of mechanism. Nature. 1961;191:144-148.
    • (1961) Nature , vol.191 , pp. 144-148
    • Mitchell, P.1
  • 2
    • 3943071150 scopus 로고    scopus 로고
    • Cytochrome C-mediated apoptosis
    • Jiang X, Wang X. Cytochrome C-mediated apoptosis. Annu Rev Biochem. 2004;73:87-106.
    • (2004) Annu Rev Biochem , vol.73 , pp. 87-106
    • Jiang, X.1    Wang, X.2
  • 5
    • 24144461689 scopus 로고    scopus 로고
    • Identification and characterization of MAVS a mitochondrial antiviral signaling protein that activates NFkappaB and IRF
    • Seth RB, Sun L, Ea CK, Chen ZJ. Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NFkappaB and IRF. Cell. 2005;122:669-682.
    • (2005) Cell , vol.122 , pp. 669-682
    • Seth, R.B.1    Sun, L.2    Ea, C.K.3    Chen, Z.J.4
  • 6
    • 0037455575 scopus 로고    scopus 로고
    • Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development
    • Chen H, Detmer SA, Ewald AJ, Griffin EE, Fraser SE, Chan DC. Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development. J Cell Biol. 2003;160: 189-200.
    • (2003) J Cell Biol , vol.160 , pp. 189-200
    • Chen, H.1    Detmer, S.A.2    Ewald, A.J.3    Griffin, E.E.4    Fraser, S.E.5    Chan, D.C.6
  • 7
    • 0018976455 scopus 로고
    • Effect of mitochondrial functions on synthesis of yeast cytochrome c
    • Siemens TV, Nichols DL, Zitomer RS. Effect of mitochondrial functions on synthesis of yeast cytochrome c. J Bacteriol. 1980;142:499-507.
    • (1980) J Bacteriol , vol.142 , pp. 499-507
    • Siemens, T.V.1    Nichols, D.L.2    Zitomer, R.S.3
  • 8
    • 0023106633 scopus 로고
    • The mitochondrial genotype can influence nuclear gene expression in yeast
    • Parikh VS, Morgan MM, Scott R, Clements LS, Butow RA. The mitochondrial genotype can influence nuclear gene expression in yeast. Science. 1987;235:576-580.
    • (1987) Science , vol.235 , pp. 576-580
    • Parikh, V.S.1    Morgan, M.M.2    Scott, R.3    Clements, L.S.4    Butow, R.A.5
  • 9
    • 0024467192 scopus 로고
    • Communication between mitochondria and the nucleus in regulation of cytochrome genes in the yeast Saccharomyces cerevisiae
    • Forsburg SL, Guarente L. Communication between mitochondria and the nucleus in regulation of cytochrome genes in the yeast Saccharomyces cerevisiae. Annu Rev Cell Biol. 1989;5:153-180.
    • (1989) Annu Rev Cell Biol , vol.5 , pp. 153-180
    • Forsburg, S.L.1    Guarente, L.2
  • 10
    • 0020393425 scopus 로고
    • Regulation of synthesis of catalases and iso-1-cytochrome c in Saccharomyces cerevisiae by glucose, oxygen and heme
    • Hörtner H, Ammerer G, Hartter E, Hamilton B, Rytka J, Bilinski T, Ruis H. Regulation of synthesis of catalases and iso-1-cytochrome c in Saccharomyces cerevisiae by glucose, oxygen and heme. Eur J Biochem. 1982;128:179-184.
    • (1982) Eur J Biochem , vol.128 , pp. 179-184
    • Hörtner, H.1    Ammerer, G.2    Hartter, E.3    Hamilton, B.4    Rytka, J.5    Bilinski, T.6    Ruis, H.7
  • 11
    • 0018264525 scopus 로고
    • Heme is necessary for the accumulation and assembly of cytochrome c oxidase subunits in Saccharomyces cerevisiae
    • Saltzgaber-Müller J, Schatz G. Heme is necessary for the accumulation and assembly of cytochrome c oxidase subunits in Saccharomyces cerevisiae. J Biol Chem. 1978;253:305-310.
    • (1978) J Biol Chem , vol.253 , pp. 305-310
    • Saltzgaber-Müller, J.1    Schatz, G.2
  • 12
    • 3943071150 scopus 로고    scopus 로고
    • Cytochrome C-mediated apoptosis
    • Jiang X, Wang X. Cytochrome C-mediated apoptosis. Annu Rev Biochem. 2004;73:87-106.
    • (2004) Annu Rev Biochem , vol.73 , pp. 87-106
    • Jiang, X.1    Wang, X.2
  • 16
    • 14844327760 scopus 로고    scopus 로고
    • Reactive oxygen species promote TNFalpha-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases
    • Kamata H, Honda S, Maeda S, Chang L, Hirata H, Karin M. Reactive oxygen species promote TNFalpha-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases. Cell. 2005;120:649-661.
    • (2005) Cell , vol.120 , pp. 649-661
    • Kamata, H.1    Honda, S.2    Maeda, S.3    Chang, L.4    Hirata, H.5    Karin, M.6
  • 17
    • 4544225647 scopus 로고    scopus 로고
    • Mitochondrial function is required for hydrogen peroxide-induced growth factor receptor transactivation and downstream signaling
    • Chen K, Thomas SR, Albano A, Murphy MP, Keaney JF Jr. Mitochondrial function is required for hydrogen peroxide-induced growth factor receptor transactivation and downstream signaling. J Biol Chem. 2004;279: 35079-35086.
    • (2004) J Biol Chem , vol.279 , pp. 35079-35086
    • Chen, K.1    Thomas, S.R.2    Albano, A.3    Murphy, M.P.4    Keaney Jr., J.F.5
  • 20
    • 0035816639 scopus 로고    scopus 로고
    • Leptin induces mitochondrial superoxide production and monocyte chemoattractant protein-1 expression in aortic endothelial cells by increasing fatty acid oxidation via protein kinase A
    • Yamagishi SI, Edelstein D, Du XL, Kaneda Y, Guzmán M, Brownlee M. Leptin induces mitochondrial superoxide production and monocyte chemoattractant protein-1 expression in aortic endothelial cells by increasing fatty acid oxidation via protein kinase A. J Biol Chem. 2001;276:25096-25100.
    • (2001) J Biol Chem , vol.276 , pp. 25096-25100
    • Yamagishi, S.I.1    Edelstein, D.2    Du, X.L.3    Kaneda, Y.4    Guzmán, M.5    Brownlee, M.6
  • 22
    • 46249108461 scopus 로고    scopus 로고
    • Regulation of ROS signal transduction by NADPH oxidase 4 localization
    • Chen K, Kirber MT, Xiao H, Yang Y, Keaney JF Jr. Regulation of ROS signal transduction by NADPH oxidase 4 localization. J Cell Biol. 2008;181: 1129-1139.
    • (2008) J Cell Biol , vol.181 , pp. 1129-1139
    • Chen, K.1    Kirber, M.T.2    Xiao, H.3    Yang, Y.4    Keaney Jr., J.F.5
  • 26
    • 0025364195 scopus 로고
    • Growth of microvessels in serum-free matrix culture of rat aorta. A quantitative assay of angiogenesis in vitro
    • Nicosia RF, Ottinetti A. Growth of microvessels in serum-free matrix culture of rat aorta. A quantitative assay of angiogenesis in vitro. Lab Invest. 1990;63:115-122.
    • (1990) Lab Invest , vol.63 , pp. 115-122
    • Nicosia, R.F.1    Ottinetti, A.2
  • 29
    • 0141891251 scopus 로고    scopus 로고
    • Activation of p53 by oxidative stress involves platelet-derived growth factor-beta receptor-mediated ataxia telangiectasia mutated (ATM) kinase activation
    • Chen K, Albano A, Ho A, Keaney JF Jr. Activation of p53 by oxidative stress involves platelet-derived growth factor-beta receptor-mediated ataxia telangiectasia mutated (ATM) kinase activation. J Biol Chem. 2003;278:39527-39533.
    • (2003) J Biol Chem , vol.278 , pp. 39527-39533
    • Chen, K.1    Albano, A.2    Ho, A.3    Keaney Jr., J.F.4
  • 30
    • 56249089371 scopus 로고    scopus 로고
    • Assessing mitochondrial morphology and dynamics using fluorescence wide-field microscopy and 3D image processing
    • Song W, Bossy B, Martin OJ, Hicks A, Lubitz S, Knott AB, Bossy-Wetzel E. Assessing mitochondrial morphology and dynamics using fluorescence wide-field microscopy and 3D image processing. Methods. 2008;46:295-303.
    • (2008) Methods , vol.46 , pp. 295-303
    • Song, W.1    Bossy, B.2    Martin, O.J.3    Hicks, A.4    Lubitz, S.5    Knott, A.B.6    Bossy-Wetzel, E.7
  • 31
    • 0037096780 scopus 로고    scopus 로고
    • UV light-damaged DNA and its interaction with human replication protein A: An atomic force microscopy study
    • Lysetska M, Knoll A, Boehringer D, Hey T, Krauss G, Krausch G. UV light-damaged DNA and its interaction with human replication protein A: an atomic force microscopy study. Nucleic Acids Res. 2002;30:2686-2691.
    • (2002) Nucleic Acids Res , vol.30 , pp. 2686-2691
    • Lysetska, M.1    Knoll, A.2    Boehringer, D.3    Hey, T.4    Krauss, G.5    Krausch, G.6
  • 32
    • 66249108601 scopus 로고    scopus 로고
    • Understanding the Warburg effect: The metabolic requirements of cell proliferation
    • Vander Heiden MG, Cantley LC, Thompson CB. Understanding the Warburg effect: the metabolic requirements of cell proliferation. Science. 2009;324:1029-1033.
    • (2009) Science , vol.324 , pp. 1029-1033
    • Vander Heiden, M.G.1    Cantley, L.C.2    Thompson, C.B.3
  • 33
    • 0042733154 scopus 로고    scopus 로고
    • AMP-activated protein kinase (AMPK) signaling in endothelial cells is essential for angiogenesis in response to hypoxic stress
    • Nagata D, Mogi M, Walsh K. AMP-activated protein kinase (AMPK) signaling in endothelial cells is essential for angiogenesis in response to hypoxic stress. J Biol Chem. 2003;278:31000-31006.
    • (2003) J Biol Chem , vol.278 , pp. 31000-31006
    • Nagata, D.1    Mogi, M.2    Walsh, K.3
  • 34
    • 0025189864 scopus 로고
    • Apparent hydroxyl radical production by peroxynitrite: Implications for endothelial injury from nitric oxide and superoxide
    • Beckman JS, Beckman TW, Chen J, Marshall PA, Freeman BA. Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide. Proc Natl Acad Sci USA. 1990;87:1620-1624.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 1620-1624
    • Beckman, J.S.1    Beckman, T.W.2    Chen, J.3    Marshall, P.A.4    Freeman, B.A.5
  • 35
    • 67749089562 scopus 로고    scopus 로고
    • A hyperfused mitochondrial state achieved at G1-S regulates cyclin e buildup and entry into S phase
    • Mitra K, Wunder C, Roysam B, Lin G, Lippincott-Schwartz J. A hyperfused mitochondrial state achieved at G1-S regulates cyclin E buildup and entry into S phase. Proc Natl Acad Sci USA. 2009;106:11960-11965.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 11960-11965
    • Mitra, K.1    Wunder, C.2    Roysam, B.3    Lin, G.4    Lippincott-Schwartz, J.5
  • 36
    • 35448960851 scopus 로고    scopus 로고
    • Functions and dysfunctions of mitochondrial dynamics
    • Detmer SA, Chan DC. Functions and dysfunctions of mitochondrial dynamics. Nat Rev Mol Cell Biol. 2007;8:870-879.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 870-879
    • Detmer, S.A.1    Chan, D.C.2
  • 37
    • 0032549811 scopus 로고    scopus 로고
    • A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis
    • Puigserver P, Wu Z, Park CW, Graves R, Wright M, Spiegelman BM. A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis. Cell. 1998;92:829-839.
    • (1998) Cell , vol.92 , pp. 829-839
    • Puigserver, P.1    Wu, Z.2    Park, C.W.3    Graves, R.4    Wright, M.5    Spiegelman, B.M.6
  • 40
    • 25144476923 scopus 로고    scopus 로고
    • Physiological functions of the mitochondrial uncoupling proteins UCP2 and UCP3
    • Brand MD, Esteves TC. Physiological functions of the mitochondrial uncoupling proteins UCP2 and UCP3. Cell Metab. 2005;2:85-93.
    • (2005) Cell Metab , vol.2 , pp. 85-93
    • Brand, M.D.1    Esteves, T.C.2
  • 41
    • 0037033039 scopus 로고    scopus 로고
    • Superoxide activates mitochondrial uncoupling protein 2 from the matrix side. Studies using targeted antioxidants
    • Echtay KS, Murphy MP, Smith RA, Talbot DA, Brand MD. Superoxide activates mitochondrial uncoupling protein 2 from the matrix side. Studies using targeted antioxidants. J Biol Chem. 2002;277:47129-47135.
    • (2002) J Biol Chem , vol.277 , pp. 47129-47135
    • Echtay, K.S.1    Murphy, M.P.2    Smith, R.A.3    Talbot, D.A.4    Brand, M.D.5
  • 46
    • 33846005165 scopus 로고    scopus 로고
    • A novel class of vascular endothelial growth factor-responsive genes that require forkhead activity for expression
    • Abid MR, Shih SC, Otu HH, Spokes KC, Okada Y, Curiel DT, Minami T, Aird WC. A novel class of vascular endothelial growth factor-responsive genes that require forkhead activity for expression. J Biol Chem. 2006;281:35544-35553.
    • (2006) J Biol Chem , vol.281 , pp. 35544-35553
    • Abid, M.R.1    Shih, S.C.2    Otu, H.H.3    Spokes, K.C.4    Okada, Y.5    Curiel, D.T.6    Minami, T.7    Aird, W.C.8
  • 48
    • 0030941458 scopus 로고    scopus 로고
    • P53, the cellular gatekeeper for growth and division
    • Levine AJ. p53, the cellular gatekeeper for growth and division. Cell. 1997;88:323-331.
    • (1997) Cell , vol.88 , pp. 323-331
    • Levine, A.J.1
  • 50
    • 2142815107 scopus 로고    scopus 로고
    • Regeneration of peroxiredoxins by p53-regulated sestrins, homologs of bacterial AhpD
    • Budanov AV, Sablina AA, Feinstein E, Koonin EV, Chumakov PM. Regeneration of peroxiredoxins by p53-regulated sestrins, homologs of bacterial AhpD. Science. 2004;304:596-600.
    • (2004) Science , vol.304 , pp. 596-600
    • Budanov, A.V.1    Sablina, A.A.2    Feinstein, E.3    Koonin, E.V.4    Chumakov, P.M.5
  • 52
    • 77958539005 scopus 로고    scopus 로고
    • Prohibitins are required for cancer cell proliferation and adhesion
    • Sievers C, Billig G, Gottschalk K, Rudel T. Prohibitins are required for cancer cell proliferation and adhesion. PLoS One. 2010;5:e12735.
    • (2010) PLoS One , vol.5
    • Sievers, C.1    Billig, G.2    Gottschalk, K.3    Rudel, T.4
  • 53
    • 78149438189 scopus 로고    scopus 로고
    • Mitochondrial uncoupling inhibits p53 mitochondrial translocation in TPA-challenged skin epidermal JB6 cells
    • Wang F, Fu X, Chen X, Chen X, Zhao Y. Mitochondrial uncoupling inhibits p53 mitochondrial translocation in TPA-challenged skin epidermal JB6 cells. PLoS One. 2010;5:e13459.
    • (2010) PLoS One , vol.5
    • Wang, F.1    Fu, X.2    Chen, X.3    Chen, X.4    Zhao, Y.5
  • 55
    • 48549088300 scopus 로고    scopus 로고
    • The Warburg effect in leukemia-stroma cocultures is mediated by mitochondrial uncoupling associated with uncoupling protein 2 activation
    • Samudio I, Fiegl M, McQueen T, Clise-Dwyer K, Andreeff M. The Warburg effect in leukemia-stroma cocultures is mediated by mitochondrial uncoupling associated with uncoupling protein 2 activation. Cancer Res. 2008;68:5198-5205.
    • (2008) Cancer Res , vol.68 , pp. 5198-5205
    • Samudio, I.1    Fiegl, M.2    McQueen, T.3    Clise-Dwyer, K.4    Andreeff, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.