The independent roles of mechanical, structural and adhesion characteristics of 3D hydrogels on the regulation of cancer invasion and dissemination

Biomaterials

Volumn 34, Issue 37, 2013, Pages 9486-9495

  Beck, Jennifer N ^a   Singh, Anirudha ^c   Rothenberg, Ashley R ^c   Elisseeff, Jennifer H ^c   Ewald, Andrew J ^a,b  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

^c JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

Breast cancer; Cell adhesion; Dissemination; Invasion; Mechanical properties; Poly(ethylene) glycol hydrogels

Indexed keywords

ADHESION CHARACTERISTIC; BASEMENT MEMBRANE PROTEINS; BREAST CANCER; CROSS-LINKING DENSITY; DISSEMINATION; INVASION; MAMMARY EPITHELIAL CELLS; SYSTEMATIC EVALUATION;

BIOLOGICAL MEMBRANES; CELL ADHESION; CELLS; COLLAGEN; DISEASES; ETHYLENE; HYDROGELS; MAMMALS; MECHANICAL PROPERTIES; PEPTIDES; POLYETHYLENE GLYCOLS; POLYMERS; RIGIDITY; TUMORS;

THREE DIMENSIONAL;

ALPHA CYCLODEXTRIN; COLLAGEN TYPE 1; MACROGOL; MATRIGEL; TISSUE SCAFFOLD;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOCOMPATIBILITY; BRANCHING MORPHOGENESIS; BREAST EPITHELIUM; CANCER CELL; CELL FUNCTION; CONTROLLED STUDY; HYDROGEL; METASTASIS; MICROENVIRONMENT; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CROSS LINKING; RIGIDITY; TUMOR INVASION; YOUNG MODULUS;

MAMMALIA;

BREAST CANCER; CELL ADHESION; DISSEMINATION; INVASION; MECHANICAL PROPERTIES; POLY(ETHYLENE) GLYCOL HYDROGELS;

ANIMALS; BIOCOMPATIBLE MATERIALS; BREAST; CELL ADHESION; CELL MOVEMENT; COLLAGEN; CYCLODEXTRINS; DRUG COMBINATIONS; FEMALE; HYDROGELS; LAMININ; MAMMARY NEOPLASMS, ANIMAL; POLYETHYLENE GLYCOLS; PROTEOGLYCANS; TUMOR CELLS, CULTURED;

EID: 84884815469     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2013.08.077     Document Type: Article

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