New synthetic aliphatic sulfonamido-quaternary ammonium salts as anticancer chemotherapeutic agents

European Journal of Medicinal Chemistry

Volumn 69, Issue , 2013, Pages 670-677

  Song, Doona ^a   Yang, Jee Sun ^a   Oh, Changmok ^a   Cui, Shuolin ^a   Kim, Bo Kyung ^b   Won, Misun ^b   Lee, Jang Ik ^a   Kim, Hwan Mook ^c   Han, Gyoonhee ^a  

^a Yonsei University   (South Korea)

^b Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^c Gachon University College of Medicine   (South Korea)

Author keywords

Aliphatic sulfonamido quaternary ammonium salts; Anticancer chemotherapeutic agents; NSC126188; Open ring moiety of quaternary ammonium salts; Perifosine; RhoB

Indexed keywords

[3 [(HEXADECANE 1 SULFONYL) METHYL AMINO] PROPYL] TRIMETHYL AMMONIUM; IODIDE; [ETHYLDIMETHYL [3-[METHYL (TETRADECANE 1 SULFONYL) AMINO] PROPYL] AMMONIUM; IODIDE]; ALIPHATIC AMINE; ALLYL [2 [(HEXADECANE 1 SULFONYL) METHYL AMINO] ETHYL] DIMETHYL AMMONIUM; BROMIDE; ALLYL DIETHYL [2 [(HEXADECANE 1 SULFONYL) METHYL AMINO] ETHYL] AMMONIUM; BROMIDE; ALLYL DIETHYL [2 [METHYL (TETRADECANE 1 SULFONYL) AMINO] ETHYL] AMMONIUM; BROMIDE; ALLYL DIMETHYL [2 [METHYL (TETRADECANE 1 SULFONYL) AMINO] ETHYL] AMMONIUM; BROMIDE; ANTINEOPLASTIC AGENT; DIETHYL [2 [(HEXADECANE 1 SULFONYL) METHYL AMINO] ETHYL] METHYL AMMONIUM; IODIDE; DIETHYL METHYL [2 [METHYL (TETRADECANE 1 SULFONYL) AMINO] ETHYL] AMMONIUM; IODIDE; ETHYL [2 [(HEXADECANE 1 SULFONYL) METHYL AMINO] ETHYL] DIMETHYL AMMONIUM; IODIDE; ETHYL [3 [(HEXADECANE 1 SULFONYL) METHYL AMINO] PROPYL]DIMETHYL AMMONIUM; IODIDE; ETHYL DIMETHYL [2 [METHYL (TETRADECANE 1 SULFONYL) AMINO] ETHYL] AMMONIUM; IODIDE; ETHYL DIMETHYL [3 [METHYL (TETRADECANE 1 SULFONYL)AMINO] PROPYL] AMMONIUM; IODIDE; HEXADECANE 1 SULFONIC ACID (2 DIETHYLAMINO ETHYL) METHYL AMIDE; HEXADECANE 1 SULFONIC ACID (2 DIMETHYLAMINO ETHYL) METHYL AMIDE; HEXADECANE 1 SULFONIC ACID (3 DIMETHYLAMINO 2,2 DIMETHYL PROPYL) AMIDE; HEXADECANE 1 SULFONIC ACID (3 DIMETHYLAMINO PROPYL) AMIDE; HEXADECANE 1 SULFONIC ACID (3 DIMETHYLAMINO PROPYL) METHYL AMIDE; QUATERNARY AMMONIUM DERIVATIVE; TETRADECANE 1 SULFONIC ACID (2 DIETHYLAMINO ETHYL) METHYL AMIDE; TETRADECANE 1 SULFONIC ACID (2 DIMETHYLAMINO ETHYL) METHYL AMIDE; TETRADECANE 1 SULFONIC ACID (3 DIMETHYLAMINO 2,2 DIMETHYL PROPYL) AMIDE; TETRADECANE 1 SULFONIC ACID (3 DIMETHYLAMINO PROPYL) AMIDE; TETRADECANE 1 SULFONIC ACID (3 DIMETHYLAMINO PROPYL) METHYL AMIDE; TRIETHYL [2 [(HEXADECANE 1 SULFONYL) METHYL AMINO] ETHYL] AMMONIUM; IODIDE; TRIETHYL [2 [METHYL (TETRADECANE 1 SULFONYL) AMINO] ETHYL] AMMONIUM; IODIDE; TRIMETHYL [2 [METHYL (TETRADECANE 1 SULFONYL) AMINO] ETHYL] AMMONIUM; IODIDE; TRIMETHYL [3 [METHYL (TETRADECANE 1 SULFONYL) AMINO]PROPYL] AMMONIUM; IODIDE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; BREAST CANCER; CANCER CELL; COLON CANCER; DRUG POTENCY; DRUG SYNTHESIS; FEMALE; GROWTH INHIBITION; HUMAN; HUMAN CELL; KIDNEY CANCER; LUNG NON SMALL CELL CANCER; MALE; PROSTATE CANCER; STOMACH CANCER; UPREGULATION;

ALIPHATIC SULFONAMIDO-QUATERNARY AMMONIUM SALTS; ANTICANCER CHEMOTHERAPEUTIC AGENTS; NSC126188; OPEN-RING MOIETY OF QUATERNARY AMMONIUM SALTS; PERIFOSINE; RHOB;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; HELA CELLS; HUMANS; MOLECULAR STRUCTURE; QUATERNARY AMMONIUM COMPOUNDS; RHOB GTP-BINDING PROTEIN; SALTS; STRUCTURE-ACTIVITY RELATIONSHIP; SULFONAMIDES;

EID: 84884787413     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2013.09.022     Document Type: Article

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