-
1
-
-
84855792427
-
Cancer statistics, 2012
-
Siegel R, Naishadham D, Jemal A, (2012) Cancer statistics, 2012. CA Cancer J Clin 62: 10-29.
-
(2012)
CA Cancer J Clin
, vol.62
, pp. 10-29
-
-
Siegel, R.1
Naishadham, D.2
Jemal, A.3
-
2
-
-
77955635233
-
Cancer statistics, 2010
-
Jemal A, Siegel R, Xu J, Ward E, (2010) Cancer statistics, 2010. CA Cancer J Clin 60: 277-300.
-
(2010)
CA Cancer J Clin
, vol.60
, pp. 277-300
-
-
Jemal, A.1
Siegel, R.2
Xu, J.3
Ward, E.4
-
3
-
-
33845896853
-
Protein arginine methyltransferases: evolution and assessment of their pharmacological and therapeutic potential
-
Krause CD, Yang ZH, Kim YS, Lee JH, Cook JR, et al. (2007) Protein arginine methyltransferases: evolution and assessment of their pharmacological and therapeutic potential. Pharmacol Ther 113: 50-87.
-
(2007)
Pharmacol Ther
, vol.113
, pp. 50-87
-
-
Krause, C.D.1
Yang, Z.H.2
Kim, Y.S.3
Lee, J.H.4
Cook, J.R.5
-
4
-
-
34547741040
-
Low levels of miR-92b/96 induce PRMT5 translation and H3R8/H4R3 methylation in mantle cell lymphoma
-
Pal S, Baiocchi RA, Byrd JC, Grever MR, Jacob ST, et al. (2007) Low levels of miR-92b/96 induce PRMT5 translation and H3R8/H4R3 methylation in mantle cell lymphoma. EMBO J 26: 3558-3569.
-
(2007)
EMBO J
, vol.26
, pp. 3558-3569
-
-
Pal, S.1
Baiocchi, R.A.2
Byrd, J.C.3
Grever, M.R.4
Jacob, S.T.5
-
5
-
-
34848885467
-
Interplay between chromatin remodelers and protein arginine methyltransferases
-
Pal S, Sif S, (2007) Interplay between chromatin remodelers and protein arginine methyltransferases. J Cell Physiol 213: 306-315.
-
(2007)
J Cell Physiol
, vol.213
, pp. 306-315
-
-
Pal, S.1
Sif, S.2
-
6
-
-
80051688829
-
Protein arginine methyltransferase 5 accelerates tumor growth by arginine methylation of the tumor suppressor programmed cell death 4
-
Powers MA, Fay MM, Factor RE, Welm AL, Ullman KS, (2011) Protein arginine methyltransferase 5 accelerates tumor growth by arginine methylation of the tumor suppressor programmed cell death 4. Cancer Res 71: 5579-5587.
-
(2011)
Cancer Res
, vol.71
, pp. 5579-5587
-
-
Powers, M.A.1
Fay, M.M.2
Factor, R.E.3
Welm, A.L.4
Ullman, K.S.5
-
7
-
-
53549103598
-
Protein arginine methyltransferase 5 suppresses the transcription of the RB family of tumor suppressors in leukemia and lymphoma cells
-
Wang L, Pal S, Sif S, (2008) Protein arginine methyltransferase 5 suppresses the transcription of the RB family of tumor suppressors in leukemia and lymphoma cells. Mol Cell Biol 28: 6262-6277.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 6262-6277
-
-
Wang, L.1
Pal, S.2
Sif, S.3
-
9
-
-
84865180674
-
Protein arginine methyltransferase 5 is essential for growth of lung cancer cells
-
Gu Z, Gao S, Zhang F, Wang Z, Ma W, et al. (2012) Protein arginine methyltransferase 5 is essential for growth of lung cancer cells. Biochem J.
-
(2012)
Biochem J
-
-
Gu, Z.1
Gao, S.2
Zhang, F.3
Wang, Z.4
Ma, W.5
-
10
-
-
84865429451
-
Protein arginine methyltransferase 5 functions in opposite ways in the cytoplasm and nucleus of prostate cancer cells
-
Gu Z, Li Y, Lee P, Liu T, Wan C, et al. (2012) Protein arginine methyltransferase 5 functions in opposite ways in the cytoplasm and nucleus of prostate cancer cells. PLoS One 7: e44033.
-
(2012)
PLoS One
, vol.7
-
-
Gu, Z.1
Li, Y.2
Lee, P.3
Liu, T.4
Wan, C.5
-
11
-
-
84865729111
-
Protein arginine methyltransferase 5 is a potential oncoprotein that upregulates G1 cyclins/cyclin-dependent kinases and the phosphoinositide 3-kinase/AKT signaling cascade
-
Wei TY, Juan CC, Hisa JY, Su LJ, Lee YC, et al. (2012) Protein arginine methyltransferase 5 is a potential oncoprotein that upregulates G1 cyclins/cyclin-dependent kinases and the phosphoinositide 3-kinase/AKT signaling cascade. Cancer Sci 103: 1640-1650.
-
(2012)
Cancer Sci
, vol.103
, pp. 1640-1650
-
-
Wei, T.Y.1
Juan, C.C.2
Hisa, J.Y.3
Su, L.J.4
Lee, Y.C.5
-
12
-
-
84875499792
-
Overexpression of PRMT5 promotes tumor cell growth and is associated with poor disease prognosis in epithelial ovarian cancer
-
Bao X, Zhao S, Liu T, Liu Y, Yang X, (2013) Overexpression of PRMT5 promotes tumor cell growth and is associated with poor disease prognosis in epithelial ovarian cancer. J Histochem Cytochem 61: 206-217.
-
(2013)
J Histochem Cytochem
, vol.61
, pp. 206-217
-
-
Bao, X.1
Zhao, S.2
Liu, T.3
Liu, Y.4
Yang, X.5
-
13
-
-
58249124384
-
Fibroblast growth factor 2 (FGF-2) is a novel substrate for arginine methylation by PRMT5
-
Bruns AF, Grothe C, Claus P, (2009) Fibroblast growth factor 2 (FGF-2) is a novel substrate for arginine methylation by PRMT5. Biol Chem 390: 59-65.
-
(2009)
Biol Chem
, vol.390
, pp. 59-65
-
-
Bruns, A.F.1
Grothe, C.2
Claus, P.3
-
15
-
-
57049087451
-
Arginine methylation regulates the p53 response
-
Jansson M, Durant ST, Cho EC, Sheahan S, Edelmann M, et al. (2008) Arginine methylation regulates the p53 response. Nat Cell Biol 10: 1431-1439.
-
(2008)
Nat Cell Biol
, vol.10
, pp. 1431-1439
-
-
Jansson, M.1
Durant, S.T.2
Cho, E.C.3
Sheahan, S.4
Edelmann, M.5
-
16
-
-
43049084803
-
The histone-binding protein COPR5 is required for nuclear functions of the protein arginine methyltransferase PRMT5
-
Lacroix M, El Messaoudi S, Rodier G, Le Cam A, Sardet C, et al. (2008) The histone-binding protein COPR5 is required for nuclear functions of the protein arginine methyltransferase PRMT5. EMBO Rep 9: 452-458.
-
(2008)
EMBO Rep
, vol.9
, pp. 452-458
-
-
Lacroix, M.1
El Messaoudi, S.2
Rodier, G.3
Le Cam, A.4
Sardet, C.5
-
17
-
-
79953214911
-
A germ cell-specific gene, Prmt5, works in somatic cell reprogramming
-
Nagamatsu G, Kosaka T, Kawasumi M, Kinoshita T, Takubo K, et al. (2011) A germ cell-specific gene, Prmt5, works in somatic cell reprogramming. J Biol Chem 286: 10641-10648.
-
(2011)
J Biol Chem
, vol.286
, pp. 10641-10648
-
-
Nagamatsu, G.1
Kosaka, T.2
Kawasumi, M.3
Kinoshita, T.4
Takubo, K.5
-
18
-
-
80052943618
-
Protein arginine methyltransferase 5 regulates ERK1/2 signal transduction amplitude and cell fate through CRAF
-
Andreu-Perez P, Esteve-Puig R, de Torre-Minguela C, Lopez-Fauqued M, Bech-Serra JJ, et al. (2011) Protein arginine methyltransferase 5 regulates ERK1/2 signal transduction amplitude and cell fate through CRAF. Sci Signal 4: ra58.
-
(2011)
Sci Signal
, vol.4
-
-
Andreu-Perez, P.1
Esteve-Puig, R.2
de Torre-Minguela, C.3
Lopez-Fauqued, M.4
Bech-Serra, J.J.5
-
19
-
-
34147150867
-
Gene and protein expression profiling of human ovarian cancer cells treated with the heat shock protein 90 inhibitor 17-allylamino-17-demethoxygeldanamycin
-
Maloney A, Clarke PA, Naaby-Hansen S, Stein R, Koopman JO, et al. (2007) Gene and protein expression profiling of human ovarian cancer cells treated with the heat shock protein 90 inhibitor 17-allylamino-17-demethoxygeldanamycin. Cancer Res 67: 3239-3253.
-
(2007)
Cancer Res
, vol.67
, pp. 3239-3253
-
-
Maloney, A.1
Clarke, P.A.2
Naaby-Hansen, S.3
Stein, R.4
Koopman, J.O.5
-
20
-
-
79953202843
-
The exon junction complex component Y14 modulates the activity of the methylosome in biogenesis of spliceosomal small nuclear ribonucleoproteins
-
Chuang TW, Peng PJ, Tarn WY, (2011) The exon junction complex component Y14 modulates the activity of the methylosome in biogenesis of spliceosomal small nuclear ribonucleoproteins. J Biol Chem 286: 8722-8728.
-
(2011)
J Biol Chem
, vol.286
, pp. 8722-8728
-
-
Chuang, T.W.1
Peng, P.J.2
Tarn, W.Y.3
-
21
-
-
79958013243
-
Histone H4 acetylation differentially modulates arginine methylation by an in Cis mechanism
-
Feng Y, Wang J, Asher S, Hoang L, Guardiani C, et al. (2011) Histone H4 acetylation differentially modulates arginine methylation by an in Cis mechanism. J Biol Chem 286: 20323-20334.
-
(2011)
J Biol Chem
, vol.286
, pp. 20323-20334
-
-
Feng, Y.1
Wang, J.2
Asher, S.3
Hoang, L.4
Guardiani, C.5
-
22
-
-
79959381350
-
A role for the arginine methylation of Rad9 in checkpoint control and cellular sensitivity to DNA damage
-
He W, Ma X, Yang X, Zhao Y, Qiu J, et al. (2011) A role for the arginine methylation of Rad9 in checkpoint control and cellular sensitivity to DNA damage. Nucleic Acids Res 39: 4719-4727.
-
(2011)
Nucleic Acids Res
, vol.39
, pp. 4719-4727
-
-
He, W.1
Ma, X.2
Yang, X.3
Zhao, Y.4
Qiu, J.5
-
23
-
-
79551606798
-
Crosstalk between Arg 1175 methylation and Tyr 1173 phosphorylation negatively modulates EGFR-mediated ERK activation
-
Hsu JM, Chen CT, Chou CK, Kuo HP, Li LY, et al. (2011) Crosstalk between Arg 1175 methylation and Tyr 1173 phosphorylation negatively modulates EGFR-mediated ERK activation. Nat Cell Biol 13: 174-181.
-
(2011)
Nat Cell Biol
, vol.13
, pp. 174-181
-
-
Hsu, J.M.1
Chen, C.T.2
Chou, C.K.3
Kuo, H.P.4
Li, L.Y.5
-
24
-
-
80055058063
-
Methylation of eukaryotic elongation factor 2 induced by basic fibroblast growth factor via mitogen-activated protein kinase
-
Jung GA, Shin BS, Jang YS, Sohn JB, Woo SR, et al. (2011) Methylation of eukaryotic elongation factor 2 induced by basic fibroblast growth factor via mitogen-activated protein kinase. Exp Mol Med 43: 550-560.
-
(2011)
Exp Mol Med
, vol.43
, pp. 550-560
-
-
Jung, G.A.1
Shin, B.S.2
Jang, Y.S.3
Sohn, J.B.4
Woo, S.R.5
-
25
-
-
79751486147
-
JAK2V617F-mediated phosphorylation of PRMT5 downregulates its methyltransferase activity and promotes myeloproliferation
-
Liu F, Zhao X, Perna F, Wang L, Koppikar P, et al. (2011) JAK2V617F-mediated phosphorylation of PRMT5 downregulates its methyltransferase activity and promotes myeloproliferation. Cancer Cell 19: 283-294.
-
(2011)
Cancer Cell
, vol.19
, pp. 283-294
-
-
Liu, F.1
Zhao, X.2
Perna, F.3
Wang, L.4
Koppikar, P.5
-
26
-
-
78650212707
-
Prmt5 is essential for early mouse development and acts in the cytoplasm to maintain ES cell pluripotency
-
Tee WW, Pardo M, Theunissen TW, Yu L, Choudhary JS, et al. (2010) Prmt5 is essential for early mouse development and acts in the cytoplasm to maintain ES cell pluripotency. Genes Dev 24: 2772-2777.
-
(2010)
Genes Dev
, vol.24
, pp. 2772-2777
-
-
Tee, W.W.1
Pardo, M.2
Theunissen, T.W.3
Yu, L.4
Choudhary, J.S.5
-
27
-
-
21844478747
-
Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma
-
Garraway LA, Widlund HR, Rubin MA, Getz G, Berger AJ, et al. (2005) Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma. Nature 436: 117-122.
-
(2005)
Nature
, vol.436
, pp. 117-122
-
-
Garraway, L.A.1
Widlund, H.R.2
Rubin, M.A.3
Getz, G.4
Berger, A.J.5
-
28
-
-
13944273767
-
Mitf cooperates with Rb1 and activates p21Cip1 expression to regulate cell cycle progression
-
Carreira S, Goodall J, Aksan I, La Rocca SA, Galibert MD, et al. (2005) Mitf cooperates with Rb1 and activates p21Cip1 expression to regulate cell cycle progression. Nature 433: 764-769.
-
(2005)
Nature
, vol.433
, pp. 764-769
-
-
Carreira, S.1
Goodall, J.2
Aksan, I.3
La Rocca, S.A.4
Galibert, M.D.5
-
29
-
-
12144254034
-
MITF links differentiation with cell cycle arrest in melanocytes by transcriptional activation of INK4A
-
Loercher AE, Tank EM, Delston RB, Harbour JW, (2005) MITF links differentiation with cell cycle arrest in melanocytes by transcriptional activation of INK4A. J Cell Biol 168: 35-40.
-
(2005)
J Cell Biol
, vol.168
, pp. 35-40
-
-
Loercher, A.E.1
Tank, E.M.2
Delston, R.B.3
Harbour, J.W.4
-
30
-
-
33845711166
-
Mitf regulation of Dia1 controls melanoma proliferation and invasiveness
-
Carreira S, Goodall J, Denat L, Rodriguez M, Nuciforo P, et al. (2006) Mitf regulation of Dia1 controls melanoma proliferation and invasiveness. Genes Dev 20: 3426-3439.
-
(2006)
Genes Dev
, vol.20
, pp. 3426-3439
-
-
Carreira, S.1
Goodall, J.2
Denat, L.3
Rodriguez, M.4
Nuciforo, P.5
-
31
-
-
0033047725
-
Systemic interferon-alpha (IFN-α) treatment leads to Stat3 inactivation in melanoma precursor lesions
-
Kirkwood JM, Farkas DL, Chakraborty A, Dyer KF, Tweardy DJ, et al. (1999) Systemic interferon-alpha (IFN-α) treatment leads to Stat3 inactivation in melanoma precursor lesions. Mol Med 5: 11-20.
-
(1999)
Mol Med
, vol.5
, pp. 11-20
-
-
Kirkwood, J.M.1
Farkas, D.L.2
Chakraborty, A.3
Dyer, K.F.4
Tweardy, D.J.5
-
32
-
-
4644303149
-
BRAF kinase gene V599E mutation in growing melanocytic lesions
-
Loewe R, Kittler H, Fischer G, Fae I, Wolff K, et al. (2004) BRAF kinase gene V599E mutation in growing melanocytic lesions. J Invest Dermatol 123: 733-736.
-
(2004)
J Invest Dermatol
, vol.123
, pp. 733-736
-
-
Loewe, R.1
Kittler, H.2
Fischer, G.3
Fae, I.4
Wolff, K.5
-
33
-
-
0037228055
-
High frequency of BRAF mutations in nevi
-
Pollock PM, Harper UL, Hansen KS, Yudt LM, Stark M, et al. (2003) High frequency of BRAF mutations in nevi. Nat Genet 33: 19-20.
-
(2003)
Nat Genet
, vol.33
, pp. 19-20
-
-
Pollock, P.M.1
Harper, U.L.2
Hansen, K.S.3
Yudt, L.M.4
Stark, M.5
-
34
-
-
77957966270
-
Nuclear cyclin D1/CDK4 kinase regulates CUL4 expression and triggers neoplastic growth via activation of the PRMT5 methyltransferase
-
Aggarwal P, Vaites LP, Kim JK, Mellert H, Gurung B, et al. (2010) Nuclear cyclin D1/CDK4 kinase regulates CUL4 expression and triggers neoplastic growth via activation of the PRMT5 methyltransferase. Cancer Cell 18: 329-340.
-
(2010)
Cancer Cell
, vol.18
, pp. 329-340
-
-
Aggarwal, P.1
Vaites, L.P.2
Kim, J.K.3
Mellert, H.4
Gurung, B.5
-
35
-
-
0037040912
-
A novel WD repeat protein component of the methylosome binds Sm proteins
-
Friesen WJ, Wyce A, Paushkin S, Abel L, Rappsilber J, et al. (2002) A novel WD repeat protein component of the methylosome binds Sm proteins. J Biol Chem 277: 8243-8247.
-
(2002)
J Biol Chem
, vol.277
, pp. 8243-8247
-
-
Friesen, W.J.1
Wyce, A.2
Paushkin, S.3
Abel, L.4
Rappsilber, J.5
-
36
-
-
79960116106
-
miR-148a promoted cell proliferation by targeting p27 in gastric cancer cells
-
Guo SL, Peng Z, Yang X, Fan KJ, Ye H, et al. (2011) miR-148a promoted cell proliferation by targeting p27 in gastric cancer cells. Int J Biol Sci 7: 567-574.
-
(2011)
Int J Biol Sci
, vol.7
, pp. 567-574
-
-
Guo, S.L.1
Peng, Z.2
Yang, X.3
Fan, K.J.4
Ye, H.5
-
38
-
-
56549129538
-
Chromatin structure analyses identify miRNA promoters
-
Ozsolak F, Poling LL, Wang Z, Liu H, Liu XS, et al. (2008) Chromatin structure analyses identify miRNA promoters. Genes Dev 22: 3172-3183.
-
(2008)
Genes Dev
, vol.22
, pp. 3172-3183
-
-
Ozsolak, F.1
Poling, L.L.2
Wang, Z.3
Liu, H.4
Liu, X.S.5
-
39
-
-
84860329438
-
miR-181b promotes hepatic stellate cells proliferation by targeting p27 and is elevated in the serum of cirrhosis patients
-
Wang B, Li W, Guo K, Xiao Y, Wang Y, et al. (2012) miR-181b promotes hepatic stellate cells proliferation by targeting p27 and is elevated in the serum of cirrhosis patients. Biochem Biophys Res Commun 421: 4-8.
-
(2012)
Biochem Biophys Res Commun
, vol.421
, pp. 4-8
-
-
Wang, B.1
Li, W.2
Guo, K.3
Xiao, Y.4
Wang, Y.5
-
40
-
-
0035831040
-
Arginine methylation of STAT1 modulates IFNalpha/beta-induced transcription
-
Mowen KA, Tang J, Zhu W, Schurter BT, Shuai K, et al. (2001) Arginine methylation of STAT1 modulates IFNalpha/beta-induced transcription. Cell 104: 731-741.
-
(2001)
Cell
, vol.104
, pp. 731-741
-
-
Mowen, K.A.1
Tang, J.2
Zhu, W.3
Schurter, B.T.4
Shuai, K.5
-
41
-
-
0033615656
-
The human homologue of the yeast proteins Skb1 and Hsl7p interacts with Jak kinases and contains protein methyltransferase activity
-
Pollack BP, Kotenko SV, He W, Izotova LS, Barnoski BL, et al. (1999) The human homologue of the yeast proteins Skb1 and Hsl7p interacts with Jak kinases and contains protein methyltransferase activity. J Biol Chem 274: 31531-31542.
-
(1999)
J Biol Chem
, vol.274
, pp. 31531-31542
-
-
Pollack, B.P.1
Kotenko, S.V.2
He, W.3
Izotova, L.S.4
Barnoski, B.L.5
-
42
-
-
65549152323
-
PRMT5, a novel TRAIL receptor-binding protein, inhibits TRAIL-induced apoptosis via nuclear factor-kappaB activation
-
Tanaka H, Hoshikawa Y, Oh-hara T, Koike S, Naito M, et al. (2009) PRMT5, a novel TRAIL receptor-binding protein, inhibits TRAIL-induced apoptosis via nuclear factor-kappaB activation. Mol Cancer Res 7: 557-569.
-
(2009)
Mol Cancer Res
, vol.7
, pp. 557-569
-
-
Tanaka, H.1
Hoshikawa, Y.2
Oh-hara, T.3
Koike, S.4
Naito, M.5
-
43
-
-
6344222803
-
Human SWI/SNF-associated PRMT5 methylates histone H3 arginine 8 and negatively regulates expression of ST7 and NM23 tumor suppressor genes
-
Pal S, Vishwanath SN, Erdjument-Bromage H, Tempst P, Sif S, (2004) Human SWI/SNF-associated PRMT5 methylates histone H3 arginine 8 and negatively regulates expression of ST7 and NM23 tumor suppressor genes. Mol Cell Biol 24: 9630-9645.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 9630-9645
-
-
Pal, S.1
Vishwanath, S.N.2
Erdjument-Bromage, H.3
Tempst, P.4
Sif, S.5
-
44
-
-
0142123234
-
mSin3A/histone deacetylase 2- and PRMT5-containing Brg1 complex is involved in transcriptional repression of the Myc target gene cad
-
Pal S, Yun R, Datta A, Lacomis L, Erdjument-Bromage H, et al. (2003) mSin3A/histone deacetylase 2- and PRMT5-containing Brg1 complex is involved in transcriptional repression of the Myc target gene cad. Mol Cell Biol 23: 7475-7487.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 7475-7487
-
-
Pal, S.1
Yun, R.2
Datta, A.3
Lacomis, L.4
Erdjument-Bromage, H.5
-
45
-
-
69849092902
-
PRMT5 is required for cell-cycle progression and p53 tumor suppressor function
-
Scoumanne A, Zhang J, Chen X, (2009) PRMT5 is required for cell-cycle progression and p53 tumor suppressor function. Nucleic Acids Res 37: 4965-4976.
-
(2009)
Nucleic Acids Res
, vol.37
, pp. 4965-4976
-
-
Scoumanne, A.1
Zhang, J.2
Chen, X.3
-
46
-
-
84884769384
-
Developing a Novel Class of Drug to Inhibit Protein Arginine Methyltransferase 5 (PRMT5) Enzyme Dysregulation in Mantle Cell Lymphoma
-
abstract #595
-
Yan F, Smith P, Alinari L, Ryu J, Yu B, et al. (2011) Developing a Novel Class of Drug to Inhibit Protein Arginine Methyltransferase 5 (PRMT5) Enzyme Dysregulation in Mantle Cell Lymphoma. ASH Annual Meeting Abstracts 118: abstract #595.
-
(2011)
ASH Annual Meeting Abstracts
, vol.118
-
-
Yan, F.1
Smith, P.2
Alinari, L.3
Ryu, J.4
Yu, B.5
-
47
-
-
74949122403
-
Methylation of histone H3 and H4 by PRMT5 regulates ribosomal RNA gene transcription
-
Majumder S, Alinari L, Roy S, Miller T, Datta J, et al. (2010) Methylation of histone H3 and H4 by PRMT5 regulates ribosomal RNA gene transcription. J Cell Biochem 109: 553-563.
-
(2010)
J Cell Biochem
, vol.109
, pp. 553-563
-
-
Majumder, S.1
Alinari, L.2
Roy, S.3
Miller, T.4
Datta, J.5
-
48
-
-
84878649723
-
The Role of Altered Nucleotide Excision Repair and UVB-Induced DNA Damage in Melanomagenesis
-
Budden T, Bowden NA, (2013) The Role of Altered Nucleotide Excision Repair and UVB-Induced DNA Damage in Melanomagenesis. Int J Mol Sci 14: 1132-1151.
-
(2013)
Int J Mol Sci
, vol.14
, pp. 1132-1151
-
-
Budden, T.1
Bowden, N.A.2
-
49
-
-
84879414700
-
UVB-Induced Melanocyte Proliferation in Neonatal Mice Driven by CCR2-Independent Recruitment of Ly6c(low)MHCII(hi) Macrophages
-
Handoko HY, Rodero MP, Boyle GM, Ferguson B, Engwerda C, et al. (2013) UVB-Induced Melanocyte Proliferation in Neonatal Mice Driven by CCR2-Independent Recruitment of Ly6c(low)MHCII(hi) Macrophages. J Invest Dermatol 133: 1803-1812.
-
(2013)
J Invest Dermatol
, vol.133
, pp. 1803-1812
-
-
Handoko, H.Y.1
Rodero, M.P.2
Boyle, G.M.3
Ferguson, B.4
Engwerda, C.5
-
50
-
-
47349089471
-
STAT3 as a biomarker of progression in atypical nevi of patients with melanoma: dose-response effects of systemic IFNα therapy
-
Wang W, Edington HD, Rao UN, Jukic DM, Wang H, et al. (2008) STAT3 as a biomarker of progression in atypical nevi of patients with melanoma: dose-response effects of systemic IFNα therapy. J Invest Dermatol 128: 1997-2002.
-
(2008)
J Invest Dermatol
, vol.128
, pp. 1997-2002
-
-
Wang, W.1
Edington, H.D.2
Rao, U.N.3
Jukic, D.M.4
Wang, H.5
-
51
-
-
84857754060
-
Protein arginine methyltransferase 5 (PRMT5) signaling suppresses protein kinase Cδ- and p38δ-dependent signaling and keratinocyte differentiation
-
Kanade SR, Eckert RL, (2012) Protein arginine methyltransferase 5 (PRMT5) signaling suppresses protein kinase Cδ- and p38δ-dependent signaling and keratinocyte differentiation. J Biol Chem 287: 7313-7323.
-
(2012)
J Biol Chem
, vol.287
, pp. 7313-7323
-
-
Kanade, S.R.1
Eckert, R.L.2
-
53
-
-
0033119037
-
Hypoxia-induced up-regulation of angiogenin in human malignant melanoma
-
Hartmann A, Kunz M, Kostlin S, Gillitzer R, Toksoy A, et al. (1999) Hypoxia-induced up-regulation of angiogenin in human malignant melanoma. Cancer Res 59: 1578-1583.
-
(1999)
Cancer Res
, vol.59
, pp. 1578-1583
-
-
Hartmann, A.1
Kunz, M.2
Kostlin, S.3
Gillitzer, R.4
Toksoy, A.5
-
54
-
-
0028062014
-
microphthalmia, a critical factor in melanocyte development, defines a discrete transcription factor family
-
Hemesath TJ, Steingrimsson E, McGill G, Hansen MJ, Vaught J, et al. (1994) microphthalmia, a critical factor in melanocyte development, defines a discrete transcription factor family. Genes Dev 8: 2770-2780.
-
(1994)
Genes Dev
, vol.8
, pp. 2770-2780
-
-
Hemesath, T.J.1
Steingrimsson, E.2
McGill, G.3
Hansen, M.J.4
Vaught, J.5
-
55
-
-
79956131573
-
Mitf is the key molecular switch between mouse or human melanoma initiating cells and their differentiated progeny
-
Cheli Y, Giuliano S, Botton T, Rocchi S, Hofman V, et al. (2011) Mitf is the key molecular switch between mouse or human melanoma initiating cells and their differentiated progeny. Oncogene 30: 2307-2318.
-
(2011)
Oncogene
, vol.30
, pp. 2307-2318
-
-
Cheli, Y.1
Giuliano, S.2
Botton, T.3
Rocchi, S.4
Hofman, V.5
-
56
-
-
50549104987
-
Oncogenic BRAF regulates melanoma proliferation through the lineage specific factor MITF
-
Wellbrock C, Rana S, Paterson H, Pickersgill H, Brummelkamp T, et al. (2008) Oncogenic BRAF regulates melanoma proliferation through the lineage specific factor MITF. PLoS One 3: e2734.
-
(2008)
PLoS One
, vol.3
-
-
Wellbrock, C.1
Rana, S.2
Paterson, H.3
Pickersgill, H.4
Brummelkamp, T.5
-
57
-
-
33750284658
-
In melanoma, RAS mutations are accompanied by switching signaling from BRAF to CRAF and disrupted cyclic AMP signaling
-
Dumaz N, Hayward R, Martin J, Ogilvie L, Hedley D, et al. (2006) In melanoma, RAS mutations are accompanied by switching signaling from BRAF to CRAF and disrupted cyclic AMP signaling. Cancer Res 66: 9483-9491.
-
(2006)
Cancer Res
, vol.66
, pp. 9483-9491
-
-
Dumaz, N.1
Hayward, R.2
Martin, J.3
Ogilvie, L.4
Hedley, D.5
-
58
-
-
77954613878
-
The small molecule curcumin analog FLLL32 induces apoptosis in melanoma cells via STAT3 inhibition and retains the cellular response to cytokines with anti-tumor activity
-
Bill MA, Fuchs JR, Li C, Yui J, Bakan C, et al. (2010) The small molecule curcumin analog FLLL32 induces apoptosis in melanoma cells via STAT3 inhibition and retains the cellular response to cytokines with anti-tumor activity. Mol Cancer 9: 165.
-
(2010)
Mol Cancer
, vol.9
, pp. 165
-
-
Bill, M.A.1
Fuchs, J.R.2
Li, C.3
Yui, J.4
Bakan, C.5
-
59
-
-
54249169659
-
IFN-alpha and bortezomib overcome Bcl-2 and Mcl-1 overexpression in melanoma cells by stimulating the extrinsic pathway of apoptosis
-
Lesinski GB, Raig ET, Guenterberg K, Brown L, Go MR, et al. (2008) IFN-alpha and bortezomib overcome Bcl-2 and Mcl-1 overexpression in melanoma cells by stimulating the extrinsic pathway of apoptosis. Cancer Res 68: 8351-8360.
-
(2008)
Cancer Res
, vol.68
, pp. 8351-8360
-
-
Lesinski, G.B.1
Raig, E.T.2
Guenterberg, K.3
Brown, L.4
Go, M.R.5
-
60
-
-
29144470346
-
Real-time quantification of microRNAs by stem-loop RT-PCR
-
Chen C, Ridzon DA, Broomer AJ, Zhou Z, Lee DH, et al. (2005) Real-time quantification of microRNAs by stem-loop RT-PCR. Nucleic Acids Res 33: e179.
-
(2005)
Nucleic Acids Res
, vol.33
-
-
Chen, C.1
Ridzon, D.A.2
Broomer, A.J.3
Zhou, Z.4
Lee, D.H.5
|