메뉴 건너뛰기




Volumn 8, Issue 9, 2013, Pages

PRMT5 Is Upregulated in Malignant and Metastatic Melanoma and Regulates Expression of MITF and p27Kip1

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN D1; CYCLIN DEPENDENT KINASE INHIBITOR 1B; MICROPHTHALMIA ASSOCIATED TRANSCRIPTION FACTOR; MICRORNA; PROTEIN ARGININE METHYLTRANSFERASE; PROTEIN ARGININE METHYLTRANSFERASE 5; PROTEIN MEP50; SMALL INTERFERING RNA; STAT3 PROTEIN; UNCLASSIFIED DRUG;

EID: 84884765018     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0074710     Document Type: Article
Times cited : (76)

References (60)
  • 3
    • 33845896853 scopus 로고    scopus 로고
    • Protein arginine methyltransferases: evolution and assessment of their pharmacological and therapeutic potential
    • Krause CD, Yang ZH, Kim YS, Lee JH, Cook JR, et al. (2007) Protein arginine methyltransferases: evolution and assessment of their pharmacological and therapeutic potential. Pharmacol Ther 113: 50-87.
    • (2007) Pharmacol Ther , vol.113 , pp. 50-87
    • Krause, C.D.1    Yang, Z.H.2    Kim, Y.S.3    Lee, J.H.4    Cook, J.R.5
  • 4
    • 34547741040 scopus 로고    scopus 로고
    • Low levels of miR-92b/96 induce PRMT5 translation and H3R8/H4R3 methylation in mantle cell lymphoma
    • Pal S, Baiocchi RA, Byrd JC, Grever MR, Jacob ST, et al. (2007) Low levels of miR-92b/96 induce PRMT5 translation and H3R8/H4R3 methylation in mantle cell lymphoma. EMBO J 26: 3558-3569.
    • (2007) EMBO J , vol.26 , pp. 3558-3569
    • Pal, S.1    Baiocchi, R.A.2    Byrd, J.C.3    Grever, M.R.4    Jacob, S.T.5
  • 5
    • 34848885467 scopus 로고    scopus 로고
    • Interplay between chromatin remodelers and protein arginine methyltransferases
    • Pal S, Sif S, (2007) Interplay between chromatin remodelers and protein arginine methyltransferases. J Cell Physiol 213: 306-315.
    • (2007) J Cell Physiol , vol.213 , pp. 306-315
    • Pal, S.1    Sif, S.2
  • 6
    • 80051688829 scopus 로고    scopus 로고
    • Protein arginine methyltransferase 5 accelerates tumor growth by arginine methylation of the tumor suppressor programmed cell death 4
    • Powers MA, Fay MM, Factor RE, Welm AL, Ullman KS, (2011) Protein arginine methyltransferase 5 accelerates tumor growth by arginine methylation of the tumor suppressor programmed cell death 4. Cancer Res 71: 5579-5587.
    • (2011) Cancer Res , vol.71 , pp. 5579-5587
    • Powers, M.A.1    Fay, M.M.2    Factor, R.E.3    Welm, A.L.4    Ullman, K.S.5
  • 7
    • 53549103598 scopus 로고    scopus 로고
    • Protein arginine methyltransferase 5 suppresses the transcription of the RB family of tumor suppressors in leukemia and lymphoma cells
    • Wang L, Pal S, Sif S, (2008) Protein arginine methyltransferase 5 suppresses the transcription of the RB family of tumor suppressors in leukemia and lymphoma cells. Mol Cell Biol 28: 6262-6277.
    • (2008) Mol Cell Biol , vol.28 , pp. 6262-6277
    • Wang, L.1    Pal, S.2    Sif, S.3
  • 9
    • 84865180674 scopus 로고    scopus 로고
    • Protein arginine methyltransferase 5 is essential for growth of lung cancer cells
    • Gu Z, Gao S, Zhang F, Wang Z, Ma W, et al. (2012) Protein arginine methyltransferase 5 is essential for growth of lung cancer cells. Biochem J.
    • (2012) Biochem J
    • Gu, Z.1    Gao, S.2    Zhang, F.3    Wang, Z.4    Ma, W.5
  • 10
    • 84865429451 scopus 로고    scopus 로고
    • Protein arginine methyltransferase 5 functions in opposite ways in the cytoplasm and nucleus of prostate cancer cells
    • Gu Z, Li Y, Lee P, Liu T, Wan C, et al. (2012) Protein arginine methyltransferase 5 functions in opposite ways in the cytoplasm and nucleus of prostate cancer cells. PLoS One 7: e44033.
    • (2012) PLoS One , vol.7
    • Gu, Z.1    Li, Y.2    Lee, P.3    Liu, T.4    Wan, C.5
  • 11
    • 84865729111 scopus 로고    scopus 로고
    • Protein arginine methyltransferase 5 is a potential oncoprotein that upregulates G1 cyclins/cyclin-dependent kinases and the phosphoinositide 3-kinase/AKT signaling cascade
    • Wei TY, Juan CC, Hisa JY, Su LJ, Lee YC, et al. (2012) Protein arginine methyltransferase 5 is a potential oncoprotein that upregulates G1 cyclins/cyclin-dependent kinases and the phosphoinositide 3-kinase/AKT signaling cascade. Cancer Sci 103: 1640-1650.
    • (2012) Cancer Sci , vol.103 , pp. 1640-1650
    • Wei, T.Y.1    Juan, C.C.2    Hisa, J.Y.3    Su, L.J.4    Lee, Y.C.5
  • 12
    • 84875499792 scopus 로고    scopus 로고
    • Overexpression of PRMT5 promotes tumor cell growth and is associated with poor disease prognosis in epithelial ovarian cancer
    • Bao X, Zhao S, Liu T, Liu Y, Yang X, (2013) Overexpression of PRMT5 promotes tumor cell growth and is associated with poor disease prognosis in epithelial ovarian cancer. J Histochem Cytochem 61: 206-217.
    • (2013) J Histochem Cytochem , vol.61 , pp. 206-217
    • Bao, X.1    Zhao, S.2    Liu, T.3    Liu, Y.4    Yang, X.5
  • 13
    • 58249124384 scopus 로고    scopus 로고
    • Fibroblast growth factor 2 (FGF-2) is a novel substrate for arginine methylation by PRMT5
    • Bruns AF, Grothe C, Claus P, (2009) Fibroblast growth factor 2 (FGF-2) is a novel substrate for arginine methylation by PRMT5. Biol Chem 390: 59-65.
    • (2009) Biol Chem , vol.390 , pp. 59-65
    • Bruns, A.F.1    Grothe, C.2    Claus, P.3
  • 14
  • 16
    • 43049084803 scopus 로고    scopus 로고
    • The histone-binding protein COPR5 is required for nuclear functions of the protein arginine methyltransferase PRMT5
    • Lacroix M, El Messaoudi S, Rodier G, Le Cam A, Sardet C, et al. (2008) The histone-binding protein COPR5 is required for nuclear functions of the protein arginine methyltransferase PRMT5. EMBO Rep 9: 452-458.
    • (2008) EMBO Rep , vol.9 , pp. 452-458
    • Lacroix, M.1    El Messaoudi, S.2    Rodier, G.3    Le Cam, A.4    Sardet, C.5
  • 17
    • 79953214911 scopus 로고    scopus 로고
    • A germ cell-specific gene, Prmt5, works in somatic cell reprogramming
    • Nagamatsu G, Kosaka T, Kawasumi M, Kinoshita T, Takubo K, et al. (2011) A germ cell-specific gene, Prmt5, works in somatic cell reprogramming. J Biol Chem 286: 10641-10648.
    • (2011) J Biol Chem , vol.286 , pp. 10641-10648
    • Nagamatsu, G.1    Kosaka, T.2    Kawasumi, M.3    Kinoshita, T.4    Takubo, K.5
  • 19
    • 34147150867 scopus 로고    scopus 로고
    • Gene and protein expression profiling of human ovarian cancer cells treated with the heat shock protein 90 inhibitor 17-allylamino-17-demethoxygeldanamycin
    • Maloney A, Clarke PA, Naaby-Hansen S, Stein R, Koopman JO, et al. (2007) Gene and protein expression profiling of human ovarian cancer cells treated with the heat shock protein 90 inhibitor 17-allylamino-17-demethoxygeldanamycin. Cancer Res 67: 3239-3253.
    • (2007) Cancer Res , vol.67 , pp. 3239-3253
    • Maloney, A.1    Clarke, P.A.2    Naaby-Hansen, S.3    Stein, R.4    Koopman, J.O.5
  • 20
    • 79953202843 scopus 로고    scopus 로고
    • The exon junction complex component Y14 modulates the activity of the methylosome in biogenesis of spliceosomal small nuclear ribonucleoproteins
    • Chuang TW, Peng PJ, Tarn WY, (2011) The exon junction complex component Y14 modulates the activity of the methylosome in biogenesis of spliceosomal small nuclear ribonucleoproteins. J Biol Chem 286: 8722-8728.
    • (2011) J Biol Chem , vol.286 , pp. 8722-8728
    • Chuang, T.W.1    Peng, P.J.2    Tarn, W.Y.3
  • 21
    • 79958013243 scopus 로고    scopus 로고
    • Histone H4 acetylation differentially modulates arginine methylation by an in Cis mechanism
    • Feng Y, Wang J, Asher S, Hoang L, Guardiani C, et al. (2011) Histone H4 acetylation differentially modulates arginine methylation by an in Cis mechanism. J Biol Chem 286: 20323-20334.
    • (2011) J Biol Chem , vol.286 , pp. 20323-20334
    • Feng, Y.1    Wang, J.2    Asher, S.3    Hoang, L.4    Guardiani, C.5
  • 22
    • 79959381350 scopus 로고    scopus 로고
    • A role for the arginine methylation of Rad9 in checkpoint control and cellular sensitivity to DNA damage
    • He W, Ma X, Yang X, Zhao Y, Qiu J, et al. (2011) A role for the arginine methylation of Rad9 in checkpoint control and cellular sensitivity to DNA damage. Nucleic Acids Res 39: 4719-4727.
    • (2011) Nucleic Acids Res , vol.39 , pp. 4719-4727
    • He, W.1    Ma, X.2    Yang, X.3    Zhao, Y.4    Qiu, J.5
  • 23
    • 79551606798 scopus 로고    scopus 로고
    • Crosstalk between Arg 1175 methylation and Tyr 1173 phosphorylation negatively modulates EGFR-mediated ERK activation
    • Hsu JM, Chen CT, Chou CK, Kuo HP, Li LY, et al. (2011) Crosstalk between Arg 1175 methylation and Tyr 1173 phosphorylation negatively modulates EGFR-mediated ERK activation. Nat Cell Biol 13: 174-181.
    • (2011) Nat Cell Biol , vol.13 , pp. 174-181
    • Hsu, J.M.1    Chen, C.T.2    Chou, C.K.3    Kuo, H.P.4    Li, L.Y.5
  • 24
    • 80055058063 scopus 로고    scopus 로고
    • Methylation of eukaryotic elongation factor 2 induced by basic fibroblast growth factor via mitogen-activated protein kinase
    • Jung GA, Shin BS, Jang YS, Sohn JB, Woo SR, et al. (2011) Methylation of eukaryotic elongation factor 2 induced by basic fibroblast growth factor via mitogen-activated protein kinase. Exp Mol Med 43: 550-560.
    • (2011) Exp Mol Med , vol.43 , pp. 550-560
    • Jung, G.A.1    Shin, B.S.2    Jang, Y.S.3    Sohn, J.B.4    Woo, S.R.5
  • 25
    • 79751486147 scopus 로고    scopus 로고
    • JAK2V617F-mediated phosphorylation of PRMT5 downregulates its methyltransferase activity and promotes myeloproliferation
    • Liu F, Zhao X, Perna F, Wang L, Koppikar P, et al. (2011) JAK2V617F-mediated phosphorylation of PRMT5 downregulates its methyltransferase activity and promotes myeloproliferation. Cancer Cell 19: 283-294.
    • (2011) Cancer Cell , vol.19 , pp. 283-294
    • Liu, F.1    Zhao, X.2    Perna, F.3    Wang, L.4    Koppikar, P.5
  • 26
    • 78650212707 scopus 로고    scopus 로고
    • Prmt5 is essential for early mouse development and acts in the cytoplasm to maintain ES cell pluripotency
    • Tee WW, Pardo M, Theunissen TW, Yu L, Choudhary JS, et al. (2010) Prmt5 is essential for early mouse development and acts in the cytoplasm to maintain ES cell pluripotency. Genes Dev 24: 2772-2777.
    • (2010) Genes Dev , vol.24 , pp. 2772-2777
    • Tee, W.W.1    Pardo, M.2    Theunissen, T.W.3    Yu, L.4    Choudhary, J.S.5
  • 27
    • 21844478747 scopus 로고    scopus 로고
    • Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma
    • Garraway LA, Widlund HR, Rubin MA, Getz G, Berger AJ, et al. (2005) Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma. Nature 436: 117-122.
    • (2005) Nature , vol.436 , pp. 117-122
    • Garraway, L.A.1    Widlund, H.R.2    Rubin, M.A.3    Getz, G.4    Berger, A.J.5
  • 28
    • 13944273767 scopus 로고    scopus 로고
    • Mitf cooperates with Rb1 and activates p21Cip1 expression to regulate cell cycle progression
    • Carreira S, Goodall J, Aksan I, La Rocca SA, Galibert MD, et al. (2005) Mitf cooperates with Rb1 and activates p21Cip1 expression to regulate cell cycle progression. Nature 433: 764-769.
    • (2005) Nature , vol.433 , pp. 764-769
    • Carreira, S.1    Goodall, J.2    Aksan, I.3    La Rocca, S.A.4    Galibert, M.D.5
  • 29
    • 12144254034 scopus 로고    scopus 로고
    • MITF links differentiation with cell cycle arrest in melanocytes by transcriptional activation of INK4A
    • Loercher AE, Tank EM, Delston RB, Harbour JW, (2005) MITF links differentiation with cell cycle arrest in melanocytes by transcriptional activation of INK4A. J Cell Biol 168: 35-40.
    • (2005) J Cell Biol , vol.168 , pp. 35-40
    • Loercher, A.E.1    Tank, E.M.2    Delston, R.B.3    Harbour, J.W.4
  • 30
    • 33845711166 scopus 로고    scopus 로고
    • Mitf regulation of Dia1 controls melanoma proliferation and invasiveness
    • Carreira S, Goodall J, Denat L, Rodriguez M, Nuciforo P, et al. (2006) Mitf regulation of Dia1 controls melanoma proliferation and invasiveness. Genes Dev 20: 3426-3439.
    • (2006) Genes Dev , vol.20 , pp. 3426-3439
    • Carreira, S.1    Goodall, J.2    Denat, L.3    Rodriguez, M.4    Nuciforo, P.5
  • 31
    • 0033047725 scopus 로고    scopus 로고
    • Systemic interferon-alpha (IFN-α) treatment leads to Stat3 inactivation in melanoma precursor lesions
    • Kirkwood JM, Farkas DL, Chakraborty A, Dyer KF, Tweardy DJ, et al. (1999) Systemic interferon-alpha (IFN-α) treatment leads to Stat3 inactivation in melanoma precursor lesions. Mol Med 5: 11-20.
    • (1999) Mol Med , vol.5 , pp. 11-20
    • Kirkwood, J.M.1    Farkas, D.L.2    Chakraborty, A.3    Dyer, K.F.4    Tweardy, D.J.5
  • 32
    • 4644303149 scopus 로고    scopus 로고
    • BRAF kinase gene V599E mutation in growing melanocytic lesions
    • Loewe R, Kittler H, Fischer G, Fae I, Wolff K, et al. (2004) BRAF kinase gene V599E mutation in growing melanocytic lesions. J Invest Dermatol 123: 733-736.
    • (2004) J Invest Dermatol , vol.123 , pp. 733-736
    • Loewe, R.1    Kittler, H.2    Fischer, G.3    Fae, I.4    Wolff, K.5
  • 34
    • 77957966270 scopus 로고    scopus 로고
    • Nuclear cyclin D1/CDK4 kinase regulates CUL4 expression and triggers neoplastic growth via activation of the PRMT5 methyltransferase
    • Aggarwal P, Vaites LP, Kim JK, Mellert H, Gurung B, et al. (2010) Nuclear cyclin D1/CDK4 kinase regulates CUL4 expression and triggers neoplastic growth via activation of the PRMT5 methyltransferase. Cancer Cell 18: 329-340.
    • (2010) Cancer Cell , vol.18 , pp. 329-340
    • Aggarwal, P.1    Vaites, L.P.2    Kim, J.K.3    Mellert, H.4    Gurung, B.5
  • 35
    • 0037040912 scopus 로고    scopus 로고
    • A novel WD repeat protein component of the methylosome binds Sm proteins
    • Friesen WJ, Wyce A, Paushkin S, Abel L, Rappsilber J, et al. (2002) A novel WD repeat protein component of the methylosome binds Sm proteins. J Biol Chem 277: 8243-8247.
    • (2002) J Biol Chem , vol.277 , pp. 8243-8247
    • Friesen, W.J.1    Wyce, A.2    Paushkin, S.3    Abel, L.4    Rappsilber, J.5
  • 36
    • 79960116106 scopus 로고    scopus 로고
    • miR-148a promoted cell proliferation by targeting p27 in gastric cancer cells
    • Guo SL, Peng Z, Yang X, Fan KJ, Ye H, et al. (2011) miR-148a promoted cell proliferation by targeting p27 in gastric cancer cells. Int J Biol Sci 7: 567-574.
    • (2011) Int J Biol Sci , vol.7 , pp. 567-574
    • Guo, S.L.1    Peng, Z.2    Yang, X.3    Fan, K.J.4    Ye, H.5
  • 38
    • 56549129538 scopus 로고    scopus 로고
    • Chromatin structure analyses identify miRNA promoters
    • Ozsolak F, Poling LL, Wang Z, Liu H, Liu XS, et al. (2008) Chromatin structure analyses identify miRNA promoters. Genes Dev 22: 3172-3183.
    • (2008) Genes Dev , vol.22 , pp. 3172-3183
    • Ozsolak, F.1    Poling, L.L.2    Wang, Z.3    Liu, H.4    Liu, X.S.5
  • 39
    • 84860329438 scopus 로고    scopus 로고
    • miR-181b promotes hepatic stellate cells proliferation by targeting p27 and is elevated in the serum of cirrhosis patients
    • Wang B, Li W, Guo K, Xiao Y, Wang Y, et al. (2012) miR-181b promotes hepatic stellate cells proliferation by targeting p27 and is elevated in the serum of cirrhosis patients. Biochem Biophys Res Commun 421: 4-8.
    • (2012) Biochem Biophys Res Commun , vol.421 , pp. 4-8
    • Wang, B.1    Li, W.2    Guo, K.3    Xiao, Y.4    Wang, Y.5
  • 40
    • 0035831040 scopus 로고    scopus 로고
    • Arginine methylation of STAT1 modulates IFNalpha/beta-induced transcription
    • Mowen KA, Tang J, Zhu W, Schurter BT, Shuai K, et al. (2001) Arginine methylation of STAT1 modulates IFNalpha/beta-induced transcription. Cell 104: 731-741.
    • (2001) Cell , vol.104 , pp. 731-741
    • Mowen, K.A.1    Tang, J.2    Zhu, W.3    Schurter, B.T.4    Shuai, K.5
  • 41
    • 0033615656 scopus 로고    scopus 로고
    • The human homologue of the yeast proteins Skb1 and Hsl7p interacts with Jak kinases and contains protein methyltransferase activity
    • Pollack BP, Kotenko SV, He W, Izotova LS, Barnoski BL, et al. (1999) The human homologue of the yeast proteins Skb1 and Hsl7p interacts with Jak kinases and contains protein methyltransferase activity. J Biol Chem 274: 31531-31542.
    • (1999) J Biol Chem , vol.274 , pp. 31531-31542
    • Pollack, B.P.1    Kotenko, S.V.2    He, W.3    Izotova, L.S.4    Barnoski, B.L.5
  • 42
    • 65549152323 scopus 로고    scopus 로고
    • PRMT5, a novel TRAIL receptor-binding protein, inhibits TRAIL-induced apoptosis via nuclear factor-kappaB activation
    • Tanaka H, Hoshikawa Y, Oh-hara T, Koike S, Naito M, et al. (2009) PRMT5, a novel TRAIL receptor-binding protein, inhibits TRAIL-induced apoptosis via nuclear factor-kappaB activation. Mol Cancer Res 7: 557-569.
    • (2009) Mol Cancer Res , vol.7 , pp. 557-569
    • Tanaka, H.1    Hoshikawa, Y.2    Oh-hara, T.3    Koike, S.4    Naito, M.5
  • 43
    • 6344222803 scopus 로고    scopus 로고
    • Human SWI/SNF-associated PRMT5 methylates histone H3 arginine 8 and negatively regulates expression of ST7 and NM23 tumor suppressor genes
    • Pal S, Vishwanath SN, Erdjument-Bromage H, Tempst P, Sif S, (2004) Human SWI/SNF-associated PRMT5 methylates histone H3 arginine 8 and negatively regulates expression of ST7 and NM23 tumor suppressor genes. Mol Cell Biol 24: 9630-9645.
    • (2004) Mol Cell Biol , vol.24 , pp. 9630-9645
    • Pal, S.1    Vishwanath, S.N.2    Erdjument-Bromage, H.3    Tempst, P.4    Sif, S.5
  • 44
    • 0142123234 scopus 로고    scopus 로고
    • mSin3A/histone deacetylase 2- and PRMT5-containing Brg1 complex is involved in transcriptional repression of the Myc target gene cad
    • Pal S, Yun R, Datta A, Lacomis L, Erdjument-Bromage H, et al. (2003) mSin3A/histone deacetylase 2- and PRMT5-containing Brg1 complex is involved in transcriptional repression of the Myc target gene cad. Mol Cell Biol 23: 7475-7487.
    • (2003) Mol Cell Biol , vol.23 , pp. 7475-7487
    • Pal, S.1    Yun, R.2    Datta, A.3    Lacomis, L.4    Erdjument-Bromage, H.5
  • 45
    • 69849092902 scopus 로고    scopus 로고
    • PRMT5 is required for cell-cycle progression and p53 tumor suppressor function
    • Scoumanne A, Zhang J, Chen X, (2009) PRMT5 is required for cell-cycle progression and p53 tumor suppressor function. Nucleic Acids Res 37: 4965-4976.
    • (2009) Nucleic Acids Res , vol.37 , pp. 4965-4976
    • Scoumanne, A.1    Zhang, J.2    Chen, X.3
  • 46
    • 84884769384 scopus 로고    scopus 로고
    • Developing a Novel Class of Drug to Inhibit Protein Arginine Methyltransferase 5 (PRMT5) Enzyme Dysregulation in Mantle Cell Lymphoma
    • abstract #595
    • Yan F, Smith P, Alinari L, Ryu J, Yu B, et al. (2011) Developing a Novel Class of Drug to Inhibit Protein Arginine Methyltransferase 5 (PRMT5) Enzyme Dysregulation in Mantle Cell Lymphoma. ASH Annual Meeting Abstracts 118: abstract #595.
    • (2011) ASH Annual Meeting Abstracts , vol.118
    • Yan, F.1    Smith, P.2    Alinari, L.3    Ryu, J.4    Yu, B.5
  • 47
    • 74949122403 scopus 로고    scopus 로고
    • Methylation of histone H3 and H4 by PRMT5 regulates ribosomal RNA gene transcription
    • Majumder S, Alinari L, Roy S, Miller T, Datta J, et al. (2010) Methylation of histone H3 and H4 by PRMT5 regulates ribosomal RNA gene transcription. J Cell Biochem 109: 553-563.
    • (2010) J Cell Biochem , vol.109 , pp. 553-563
    • Majumder, S.1    Alinari, L.2    Roy, S.3    Miller, T.4    Datta, J.5
  • 48
    • 84878649723 scopus 로고    scopus 로고
    • The Role of Altered Nucleotide Excision Repair and UVB-Induced DNA Damage in Melanomagenesis
    • Budden T, Bowden NA, (2013) The Role of Altered Nucleotide Excision Repair and UVB-Induced DNA Damage in Melanomagenesis. Int J Mol Sci 14: 1132-1151.
    • (2013) Int J Mol Sci , vol.14 , pp. 1132-1151
    • Budden, T.1    Bowden, N.A.2
  • 49
    • 84879414700 scopus 로고    scopus 로고
    • UVB-Induced Melanocyte Proliferation in Neonatal Mice Driven by CCR2-Independent Recruitment of Ly6c(low)MHCII(hi) Macrophages
    • Handoko HY, Rodero MP, Boyle GM, Ferguson B, Engwerda C, et al. (2013) UVB-Induced Melanocyte Proliferation in Neonatal Mice Driven by CCR2-Independent Recruitment of Ly6c(low)MHCII(hi) Macrophages. J Invest Dermatol 133: 1803-1812.
    • (2013) J Invest Dermatol , vol.133 , pp. 1803-1812
    • Handoko, H.Y.1    Rodero, M.P.2    Boyle, G.M.3    Ferguson, B.4    Engwerda, C.5
  • 50
    • 47349089471 scopus 로고    scopus 로고
    • STAT3 as a biomarker of progression in atypical nevi of patients with melanoma: dose-response effects of systemic IFNα therapy
    • Wang W, Edington HD, Rao UN, Jukic DM, Wang H, et al. (2008) STAT3 as a biomarker of progression in atypical nevi of patients with melanoma: dose-response effects of systemic IFNα therapy. J Invest Dermatol 128: 1997-2002.
    • (2008) J Invest Dermatol , vol.128 , pp. 1997-2002
    • Wang, W.1    Edington, H.D.2    Rao, U.N.3    Jukic, D.M.4    Wang, H.5
  • 51
    • 84857754060 scopus 로고    scopus 로고
    • Protein arginine methyltransferase 5 (PRMT5) signaling suppresses protein kinase Cδ- and p38δ-dependent signaling and keratinocyte differentiation
    • Kanade SR, Eckert RL, (2012) Protein arginine methyltransferase 5 (PRMT5) signaling suppresses protein kinase Cδ- and p38δ-dependent signaling and keratinocyte differentiation. J Biol Chem 287: 7313-7323.
    • (2012) J Biol Chem , vol.287 , pp. 7313-7323
    • Kanade, S.R.1    Eckert, R.L.2
  • 52
    • 0028351478 scopus 로고
    • Oxygen tension measurements of head and neck cancers
    • Terris DJ, Dunphy EP, (1994) Oxygen tension measurements of head and neck cancers. Arch Otolaryngol Head Neck Surg 120: 283-287.
    • (1994) Arch Otolaryngol Head Neck Surg , vol.120 , pp. 283-287
    • Terris, D.J.1    Dunphy, E.P.2
  • 53
    • 0033119037 scopus 로고    scopus 로고
    • Hypoxia-induced up-regulation of angiogenin in human malignant melanoma
    • Hartmann A, Kunz M, Kostlin S, Gillitzer R, Toksoy A, et al. (1999) Hypoxia-induced up-regulation of angiogenin in human malignant melanoma. Cancer Res 59: 1578-1583.
    • (1999) Cancer Res , vol.59 , pp. 1578-1583
    • Hartmann, A.1    Kunz, M.2    Kostlin, S.3    Gillitzer, R.4    Toksoy, A.5
  • 54
    • 0028062014 scopus 로고
    • microphthalmia, a critical factor in melanocyte development, defines a discrete transcription factor family
    • Hemesath TJ, Steingrimsson E, McGill G, Hansen MJ, Vaught J, et al. (1994) microphthalmia, a critical factor in melanocyte development, defines a discrete transcription factor family. Genes Dev 8: 2770-2780.
    • (1994) Genes Dev , vol.8 , pp. 2770-2780
    • Hemesath, T.J.1    Steingrimsson, E.2    McGill, G.3    Hansen, M.J.4    Vaught, J.5
  • 55
    • 79956131573 scopus 로고    scopus 로고
    • Mitf is the key molecular switch between mouse or human melanoma initiating cells and their differentiated progeny
    • Cheli Y, Giuliano S, Botton T, Rocchi S, Hofman V, et al. (2011) Mitf is the key molecular switch between mouse or human melanoma initiating cells and their differentiated progeny. Oncogene 30: 2307-2318.
    • (2011) Oncogene , vol.30 , pp. 2307-2318
    • Cheli, Y.1    Giuliano, S.2    Botton, T.3    Rocchi, S.4    Hofman, V.5
  • 56
    • 50549104987 scopus 로고    scopus 로고
    • Oncogenic BRAF regulates melanoma proliferation through the lineage specific factor MITF
    • Wellbrock C, Rana S, Paterson H, Pickersgill H, Brummelkamp T, et al. (2008) Oncogenic BRAF regulates melanoma proliferation through the lineage specific factor MITF. PLoS One 3: e2734.
    • (2008) PLoS One , vol.3
    • Wellbrock, C.1    Rana, S.2    Paterson, H.3    Pickersgill, H.4    Brummelkamp, T.5
  • 57
    • 33750284658 scopus 로고    scopus 로고
    • In melanoma, RAS mutations are accompanied by switching signaling from BRAF to CRAF and disrupted cyclic AMP signaling
    • Dumaz N, Hayward R, Martin J, Ogilvie L, Hedley D, et al. (2006) In melanoma, RAS mutations are accompanied by switching signaling from BRAF to CRAF and disrupted cyclic AMP signaling. Cancer Res 66: 9483-9491.
    • (2006) Cancer Res , vol.66 , pp. 9483-9491
    • Dumaz, N.1    Hayward, R.2    Martin, J.3    Ogilvie, L.4    Hedley, D.5
  • 58
    • 77954613878 scopus 로고    scopus 로고
    • The small molecule curcumin analog FLLL32 induces apoptosis in melanoma cells via STAT3 inhibition and retains the cellular response to cytokines with anti-tumor activity
    • Bill MA, Fuchs JR, Li C, Yui J, Bakan C, et al. (2010) The small molecule curcumin analog FLLL32 induces apoptosis in melanoma cells via STAT3 inhibition and retains the cellular response to cytokines with anti-tumor activity. Mol Cancer 9: 165.
    • (2010) Mol Cancer , vol.9 , pp. 165
    • Bill, M.A.1    Fuchs, J.R.2    Li, C.3    Yui, J.4    Bakan, C.5
  • 59
    • 54249169659 scopus 로고    scopus 로고
    • IFN-alpha and bortezomib overcome Bcl-2 and Mcl-1 overexpression in melanoma cells by stimulating the extrinsic pathway of apoptosis
    • Lesinski GB, Raig ET, Guenterberg K, Brown L, Go MR, et al. (2008) IFN-alpha and bortezomib overcome Bcl-2 and Mcl-1 overexpression in melanoma cells by stimulating the extrinsic pathway of apoptosis. Cancer Res 68: 8351-8360.
    • (2008) Cancer Res , vol.68 , pp. 8351-8360
    • Lesinski, G.B.1    Raig, E.T.2    Guenterberg, K.3    Brown, L.4    Go, M.R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.