Vitamin D and bone mineral metabolism in hepatogastrointestinal diseases

Vitamin D

Volumn , Issue , 2011, Pages 1299-1323

  Bikle, Daniel D ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84884757658     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-0-12-381978-9.10069-1     Document Type: Chapter

References (309)

1. Bikle D.D., Morrissey R.L., Zolock D.T., Rasmussen H. The intestinal response to vitamin D. Rev Physiol. Biochem. Pharmacol. 1981, 89:63-142.
2. Khanal R.C., Nemere I. Regulation of intestinal calcium transport. Ann. Rev. Nutr. 2008, 28:179-196.
3. Riedt C.S., Brolin R.E., Sherrell R.M., Field M.P., Shapses S.A. True fractional calcium absorption is decreased after Roux-en-Y gastric bypass surgery. Obesity Silver Spring, Md. 2006, 14:1940-1948.
4. Heaney R.P., Skillman T.G. Secretion and excretion of calcium by the human gastrointestinal tract. J. Lab. Clin. Med. 1964, 64:29-41.
5. Benn B.S., Ajibade D., Porta A., Dhawan P., Hediger M., Peng J.B., et al. Active intestinal calcium transport in the absence of transient receptor potential vanilloid type 6 and calbindin-D9k. Endocrinology 2008, 149:3196-3205.
6. Fudge N.J., Kovacs C.S. Pregnancy up-regulates intestinal calcium absorption and skeletal mineralization independently of the vitamin D receptor. Endocrinology 2010, 151:886-895.
7. Heaney R.P. Calcium in the prevention and treatment of osteoporosis. J. Intern. Med. 1992, 231:169-180.
8. Hasling C., Charles P., Jensen F.T., Mosekilde L. Calcium metabolism in postmenopausal osteoporosis: the influence of dietary calcium and net absorbed calcium. J. Bone Miner. Res. 1990, 5:939-946.
9. Bullamore J.R., Wilkinson R., Gallagher J.C., Nordin B.E., Marshall D.H. Effect of age on calcium absorption. Lancet 1970, 2:535-537.
10. Crilly R.G., Francis R.M., Nordin B.E. Steroid hormones, ageing and bone. Clin. Endocrinol. Metab. 1981, 10:115-139.
11. Ireland P., Fordtran J.S. Effect of dietary calcium and age on jejunal calcium absorption in humans studied by intestinal perfusion. J. Clin. Invest. 1973, 52:2672-2681.
12. Gallagher J.C., Riggs B.L., Eisman J., Hamstra A., Arnaud S.B., DeLuca H.F. Intestinal calcium absorption and serum vitamin D metabolites in normal subjects and osteoporotic patients: effect of age and dietary calcium. J. Clin. Invest. 1979, 64:729-736.
13. Heaney R.P., Recker R.R., Stegman M.R., Moy A.J. Calcium absorption in women: relationships to calcium intake, estrogen status, and age. J. Bone Miner. Res. 1989, 4:469-475.
14. Caniggia A., Gennari C., Bianchi V., Guideri R. Intestinal absorption of 45Ca in senile osteoporosis. Acta. Medica Scandinavica 1963, 173:613-617.
15. Gallagher J.C., Riggs B.L., DeLuca H.F. Effect of estrogen on calcium absorption and serum vitamin D metabolites in postmenopausal osteoporosis. J. Clin. Endocrinol. Metab. 1980, 51:1359-1364.
16. Riggs B.L., Nelson K.I. Effect of long term treatment with calcitriol on calcium absorption and mineral metabolism in postmenopausal osteoporosis. J. Clin. Endocrinol. Metab. 1985, 61:457-461.
17. Eastell R., Yergey A.L., Vieira N.E., Cedel S.L., Kumar R., Riggs B.L. Interrelationship among vitamin D metabolism, true calcium absorption, parathyroid function, and age in women: evidence of an age-related intestinal resistance to 1,25-dihydroxyvitamin D action. J. Bone Miner. Res. 1991, 6:125-132.
18. Heaney R.P., Recker R.R., Saville P.D. Calcium balance and calcium requirements in middle-aged women. Am. J. Clin. Nutr. 1977, 30:1603-1611.
19. Gennari C., Agnusdei D., Nardi P., Civitelli R. Estrogen preserves a normal intestinal responsiveness to 1,25-dihydroxyvitamin D3 in oophorectomized women. J. Clin. Endocrinol. Metab. 1990, 71:1288-1293.
20. Caniggia A., Nuti R., Lore F., Martini G., Turchetti V., Righi G. Long-term treatment with calcitriol in postmenopausal osteoporosis. Metabolism 1990, 39:43-49.
21. Zerwekh J.E., Sakhaee K., Glass K., Pak C.Y. Long term 25-hydroxyvitamin D3 therapy in postmenopausal osteoporosis: demonstration of responsive and nonresponsive subgroups. J. Clin. Endocrinol. Metab. 1983, 56:410-413.
22. Stock J.L., Coderre J.A., Mallette L.E. Effects of a short course of estrogen on mineral metabolism in postmenopausal women. J. Clin. Endocrinol. Metab. 1985, 61:595-600.
23. Bikle D.D., Halloran B.P., Harris S.T., Portale A.A. Progestin antagonism of estrogen stimulated 1,25-dihydroxyvitamin D levels. J. Clin. Endocrinol. Metab. 1992, 75:519-523.
24. Cheema C., Grant B.F., Marcus R. Effects of estrogen on circulating "free" and total 1,25-dihydroxyvitamin D and on the parathyroid-vitamin D axis in postmenopausal women. J. Clin. Invest. 1989, 83:537-542.
25. Arjmandi B.H., Salih M.A., Herbert D.C., Sims S.H., Kalu D.N. Evidence for estrogen receptor-linked calcium transport in the intestine. Bone Miner. 1993, 21:63-74.
26. Francis R.M., Peacock M., Taylor G.A., Storer J.H., Nordin B.E. Calcium malabsorption in elderly women with vertebral fractures: evidence for resistance to the action of vitamin D metabolites on the bowel. Clin. Sci. (Lond.) 1984, 66:103-107.
27. Ebeling P.R., Sandgren M.E., DiMagno E.P., Lane A.W., DeLuca H.F., Riggs B.L. Evidence of an age-related decrease in intestinal responsiveness to vitamin D: relationship between serum 1,25-dihydroxyvitamin D3 and intestinal vitamin D receptor concentrations in normal women. J. Clin. Endocrinol. Metab. 1992, 75:176-182.
28. van Abel M., Huybers S., Hoenderop J.G., van der Kemp A.W., van Leeuwen J.P., Bindels R.J. Age-dependent alterations in Ca2+ homeostasis: role of TRPV5 and TRPV6. Am. J. Physiol. Renal Physiol. 2006, 291:F1177-1183.
29. Kobayashi A., Kawai S., Obe Y., Nagashima Y. Effects of dietary lactose and lactase preparation on the intestinal absorption of calcium and magnesium in normal infants. Am. J. Clin. Nutr. 1975, 28:681-683.
30. Ziegler E.E., Fomon S.J. Lactose enhances mineral absorption in infancy. J. Pediatr. Gastroenterol. Nutr. 1983, 2:288-294.
31. Birge S.J., Keutmann H.T., Cuatrecasas P., Whedon G.D. Osteoporosis, intestinal lactase deficiency and low dietary calcium intake. N. Engl. J. Med. 1967, 276:445-448.
32. Newcomer A.D., Hodgson S.F., McGill D.B., Thomas P.J. Lactase deficiency: prevalence in osteoporosis. Ann. Intern. Med. 1978, 89:218-220.
33. Horowitz M., Wishart J., Mundy L., Nordin B.E. Lactose and calcium absorption in postmenopausal osteoporosis. Arch. Intern. Med. 1987, 147:534-536.
34. Kocian J., Skala I., Bakos K. Calcium absorption from milk and lactose-free milk in healthy subjects and patients with lactose intolerance. Digestion 1973, 9:317-324.
35. Cochet B., Jung A., Griessen M., Bartholdi P., Schaller P., Donath A. Effects of lactose on intestinal calcium absorption in normal and lactase-deficient subjects. Gastroenterology 1983, 84:935-940.
36. Griessen M., Cochet B., Infante F., Jung A., Bartholdi P., Donath A., et al. Calcium absorption from milk in lactase-deficient subjects. Am. J. Clin. Nutr. 1989, 49:377-384.
37. Heaney R.P., Recker R.R. Effects of nitrogen, phosphorus, and caffeine on calcium balance in women. J. Lab. Clin. Med. 1982, 99:46-55.
38. Spencer H., Kramer L., Osis D., Norris C. Effect of phosphorus on the absorption of calcium and on the calcium balance in man. J. Nutr. 1978, 108:447-457.
39. Hegsted M., Schuette S.A., Zemel M.B., Linkswiler H.M. Urinary calcium and calcium balance in young men as affected by level of protein and phosphorus intake. J. Nutr. 1981, 111:553-562.
40. Calvo M.S. Dietary phosphorus, calcium metabolism and bone. J. Nutr. 1993, 123:1627-1633.
41. Antoniucci D.M., Yamashita T., Portale A.A. Dietary phosphorus regulates serum fibroblast growth factor-23 concentrations in healthy men. J. Clin. Endocrinol. Metab. 2006, 91:3144-3149.
42. McCance R.A., Widdowson E.M. Mineral metabolism of healthy adults on white and brown bread dietaries. J. Physiol. 1942, 101:44-85.
43. Reinhold J.G., Faradji B., Abadi P., Ismail-Beigi F. Decreased absorption of calcium, magnesium, zinc and phosphorus by humans due to increased fiber and phosphorus consumption as wheat bread. J. Nutr. 1976, 106:493-503.
44. Sandstead H.H., Klevay L.M., Jacob R.A., Munoz J.M. Effects of dietary fiber and protein level on mineral element metabolism 1979, 147-156. Academic Press, New York. G.E. Inglett, S.I. Falkehaged (Eds.).
45. Kelsey J.T., Behall K.M., Parather E.S. Effect of fiber from fruits and vegetables on metabolic responses on human subjects. 11. Calcium, magnesium, iron and silicon balances. Am. J. Clin. Nutr. 1979, 32:1876-1880.
46. Hollander D., Muralidhara K.S., Zimmerman A. Vitamin D-3 intestinal absorption in vivo: influence of fatty acids, bile salts, and perfusate pH on absorption. Gut 1978, 19:267-272.
47. Sitrin M.D., Pollack K.L., Bolt M.J., Rosenberg I.H. Comparison of vitamin D and 25-hydroxyvitamin D absorption in the rat. Am. J. Physiol. 1982, 242:G326-332.
48. Thompson G.R., Lewis B., Booth C.C. Absorption of vitamin D3-3H in control subjects and patients with intestinal malabsorption. J. Clin. Invest. 1966, 45:94-102.
49. Blomstrand R., Forsgren L. Intestinal absorption and esterification of vitamin D3-1,2-3H in man. Acta Chem. Scandinavica 1967, 21:1662-1663.
50. Hollander D., Rim E., Morgan D. Intestinal absorption of 25-hydroxyvitamin D3 in unanesthetized rat. Am. J. Physiol. 1979, 236:E441-445.
51. Davies M., Mawer E.B., Krawitt E.L. Comparative absorption of vitamin D3 and 25-hydroxyvitamin D3 in intestinal disease. Gut 1980, 21:287-292.
52. Krawitt E.L., Chastenay B.F. 25-Hydroxy vitamin D absorption test in patients with gastrointestinal disorders. Calcif. Tissue Int. 1980, 32:183-187.
53. Arnaud S.B., Goldsmith R.S., Lambert P.W., Go V.L. 25-Hydroxyvitamin D3: evidence of an enterohepatic circulation in man. Proc. Soc. Exp. Biol. Med. 1975, 149:570-572.
54. Wiesner R.H., Kumar R., Seeman E., Go V.L. Enterohepatic physiology of 1,25-dihydroxyvitamin D3 metabolites in normal man. J. Lab Clin. Med. 1980, 96:1094-1100.
55. Kumar R., Nagubandi S., Mattox V.R., Londowski J.M. Enterohepatic physiology of 1,25-dihydroxyvitamin D3. J. Clin. Invest. 1980, 65:277-284.
56. Avioli L.V., Lee S.W., McDonald J.E., Lund J., DeLuca H.F. Metabolism of vitamin D3-3H in human subjects: distribution in blood, bile, feces, and urine. J. Clin. Invest. 1967, 46:983-992.
57. Kumar R. Hepatic and intestinal osteodystrophy and the hepatobiliary metabolism of vitamin D. Ann. Intern. Med. 1983, 98:662-663.
58. Clements M.R., Chalmers T.M., Fraser D.R. Enterohepatic circulation of vitamin D: a reappraisal of the hypothesis. Lancet 1984, 1:1376-1379.
59. Boas S.R., Hageman J.R., Ho L.T., Liveris M. Very high-dose ergocalciferol is effective for correcting vitamin D deficiency in children and young adults with cystic fibrosis. J. Cyst. Fibros. 2009, 8:270-272.
60. Andersson S., Davis D.L., Dahlbäck H., Jörnvall H., Russell D.W. Cloning, structure, and expression of the mitochondrial cytochrome P-450 sterol 26-hydroxylase, a bile acid biosynthetic enzyme. J. Biol. Chem. 1989, 264:8222-8229.
61. Usui E., Noshiro M., Okuda K. Molecular cloning of cDNA for vitamin D3 25-hydroxylase from rat liver mitochondria. FEBS Lett. 1990, 262:135-138.
62. Cali J.J., Russell D.W. Characterization of human sterol 27-hydroxylase. A mitochondrial cytochrome P-450 that catalyzes multiple oxidation reaction in bile acid biosynthesis. J. Biol. Chem. 1991, 266:7774-7778.
63. Ichikawa F., Sato K., Nanjo M., Nishii Y., Shinki T., Takahashi N., et al. Mouse primary osteoblasts express vitamin D3 25-hydroxylase mRNA and convert 1 alpha-hydroxyvitamin D3 into 1 alpha,25-dihydroxyvitamin D3. Bone 1995, 16:129-135.
64. Cali J.J., Hsieh C.L., Francke U., Russell D.W. Mutations in the bile acid biosynthetic enzyme sterol 27-hydroxylase underlie cerebrotendinous xanthomatosis. J. Biol. Chem. 1991, 266:7779-7783.
65. Leitersdorf E., Reshef A., Meiner V., Levitzki R., Schwartz S.P., Dann E.J., et al. Frameshift and splice-junction mutations in the sterol 27-hydroxylase gene cause cerebrotendinous xanthomatosis in Jews or Moroccan origin. J. Clin. Invest. 1993, 91:2488-2496.
66. Berginer V.M., Shany S., Alkalay D., Berginer J., Dekel S., Salen G., et al. Osteoporosis and increased bone fractures in cerebrotendinous xanthomatosis [see comments]. Metabolism 1993, 42:69-74.
67. Leitersdorf E., Safadi R., Meiner V., Reshef A., Björkhem I., Friedlander Y., et al. Cerebrotendinous xanthomatosis in the Israeli Druze: molecular genetics and phenotypic characteristics. Am. J. Hum. Genet. 1994, 55:907-915.
68. Guo Y.D., Strugnell S., Jones G. Identification of a human liver mitochondrial cytochrome P-450 cDNA corresponding to the vitamin D3-25-hydroxylase. J. Bone Min. Res. 1991, 6:S120.
69. Guo Y.D., Strugnell S., Back D.W., Jones G. Transfected human liver cytochrome P-450 hydroxylates vitamin D analogs at different side-chain positions. Proc. Natl. Acad. Sci. USA 1993, 90:8668-8672.
70. Romagnoli E., Mascia M.L., Cipriani C., Fassino V., Mazzei F., D'Erasmo E., Carnevale V., Scillitani A., Minisola S. Short and long-term variations in serum calciotropic hormones after a single very large dose of ergocalciferol (vitamin D2) or cholecalciferol (vitamin D3) in the elderly. J. Clin. Endocrinol. Metab. 2008, 93:3015-3020.
71. Cheng J.B., Motola D.L., Mangelsdorf D.J., Russell D.W. De-orphanization of cytochrome P450 2R1: a microsomal vitamin D 25-hydroxilase. J. Biol. Chem. 2003, 278:38084-38093.
72. Cheng J.B., Levine M.A., Bell N.H., Mangelsdorf D.J., Russell D.W. Genetic evidence that the human CYP2R1 enzyme is a key vitamin D 25-hydroxylase. Proc. Natl. Acad. Sci. USA 2004, 101:7711-7715.
73. Theodoropoulos C., Demers C., Mirshahi A., Gascon-Barre M. 1,25-Dihydroxyvitamin D(3) downregulates the rat intestinal vitamin D(3)-25-hydroxylase CYP27A. Am. J. Physiol. Endocrinol. Metab. 2001, 281:E315-325.
74. Axen E., Postlind H., Wikvall K. Effects on CYP27 mRNA expression in rat kidney and liver by 1 alpha, 25-dihydroxyvitamin D3, a suppressor of renal 25-hydroxyvitamin D3 1 alpha-hydroxylase activity. Biochem. Biophys. Res. Commun. 1995, 215:136-141.
75. Vlahcevic Z.R., Jairath S.K., Heuman D.M., Stravitz R.T., Hylemon P.B., Avadhani N.G., et al. Transcriptional regulation of hepatic sterol 27-hydroxylase by bile acids. Am. J. Physiol. 1996, 270:G646-652.
76. Twisk J., Hoekman M.F., Lehmann E.M., Meijer P., Mager W.H., Princen H.M. Insulin suppresses bile acid synthesis in cultured rat hepatocytes by down-regulation of cholesterol 7 alpha-hydroxylase and sterol 27-hydroxylase gene transcription. Hepatology 1995, 21:501-510.
77. Stravitz R.T., Vlahcevic Z.R., Russell T.L., Heizer M.L., Avadhani N.G., Hylemon P.B. Regulation of sterol 27-hydroxylase and an alternative pathway of bile acid biosynthesis in primary cultures of rat hepatocytes. J. Steroid Biochem. Mol. Biol. 1996, 57:337-347.
78. Saarem K., Pedersen J.I. Sex differences in the hydroxylation of cholecalciferol and of 5 beta-cholestane-3 alpha, 7 alpha, 12 alpha-triol in rat liver. Biochem. J. 1987, 247:73-78.
79. Bauer D.C., Browner W.S., Cauley J.A., Orwoll E.S., Scott J.C., Black D.M., et al. Factors associated with appendicular bone mass in older women. The Study of Osteoporotic Fractures Research Group. Ann. Intern. Med. 1993, 118:657-665.
80. Eddy R.L. Metabolic bone disease after gastrectomy. Am. J. Med. 1971, 50:442-449.
81. Mellstrom D., Johansson C., Johnell O., Lindstedt G., Lundberg P.A., Obrant K., et al. Osteoporosis, metabolic aberrations, and increased risk for vertebral fractures after partial gastrectomy. Calcif. Tissue Int. 1993, 53:370-377.
82. Deller D.J., Begley M.D., Edwards R.G., Addison M. Metabolic effects of partial gastrectomy with special reference to calcium and folic acid. I. Changes in calcium metabolism and the bones. Gut 1964, 5:218-225.
83. Deller D.J., Edwards R.G., Addison M. Calcium metabolism and the bones after partial gastrectomy. II. The nature and cause of the bone disorder. Australas. Ann. Med. 1963, 12:295-309.
84. Morgan D.B., Paterson C.R., Woods C.G., Pulvertaft C.N., Fourman P. Search for osteomalacia in 1228 patients after gastrectomy and other operations on the stomach. Lancet 1965, 2:1085-1088.
85. Morgan D.B., Paterson C.R., Woods C.G., Pulvertaft C.N., Fourman P. Osteomalacia after gastrectomy. A response to very small doses of vitamin D. Lancet 1965, 2:1089-1091.
86. Tovey F.I., Karamanolis D.G., Godfrey J., Clark C.G. Post-gastrectomy nutrition: methods of outpatient screening for early osteomalacia. Hum. Nutr. 1985, 39:439-446.
87. Tovey F.I., Godfrey J.E., Lewin M.R. A gastrectomy population: 25-30 years on. Postgrad. Med. J. 1990, 66:450-456.
88. Coates P.S., Fernstrom J.D., Fernstrom M.H., Schauer P.R., Greenspan S.L. Gastric bypass surgery for morbid obesity leads to an increase in bone turnover and a decrease in bone mass. J. Clin. Endocrinol. Metab. 2004, 89:1061-1065.
89. Marceau P., Biron S., Lebel S., Marceau S., Hould F.S., Simard S., et al. Does bone change after biliopancreatic diversion?. J. Gastrointest. Surg. 2002, 6:690-698.
90. Melton L.J., Crowson C.S., Khosla S., O'Fallon W.M. Fracture risk after surgery for peptic ulcer disease: a population-based cohort study. Bone 1999, 25:61-67.
91. Morgan D.B., Hunt G., Paterson C.R. The osteomalacia syndrome after stomach operations. Q. J. Med. 1970, 39:395-410.
92. Garrick R., Ireland A.W., Posen S. Bone abnormalities after gastric surgery. A prospective histological study. Ann. Intern. Med. 1971, 75:221-225.
93. Gregory D.H., Van Uelft R. Calcium absorption following gastric resection. Am. J. Gastroenterol. 1972, 57:34-40.
94. Nilas L., Christiansen C. Influence of PTH and 1,25(OH)2D on calcium homeostasis and bone mineral content after gastric surgery. Calcif. Tissue Int. 1985, 37:461-466.
95. Kozawa K., Imawari M., Shimazu H., Kobori O., Osuga T., Morioka Y. Vitamin D status after total gastrectomy. Digest. Dis. Sci. 1984, 29:411-416.
96. von Lilienfeld-Toal H., Mackes K.G., Kodrat G., Ochs H., Sonnenberg A. Plasma 25-hydroxyvitamin D and urinary cyclic AMP in German patients with subtotal gastrectomy (Billroth II). Am. J. Digest. Dis. 1977, 22:633-636.
97. Klein K.B., Orwoll E.S., Lieberman D.A., Meier D.E., McClung M.R., Parfitt A.M. Metabolic bone disease in asymptomatic men after partial gastrectomy with Billroth II anastomosis. Gastroenterology 1987, 92:608-616.
98. Davies M., Heys S.E., Selby P.L., Berry J.L., Mawer E.B. Increased catabolism of 25-hydroxyvitamin D in patients with partial gastrectomy and elevated 1,25-dihydroxyvitamin D levels. Implications for metabolic bone disease. J. Clin. Endocrinol. Metab. 1997, 82:209-212.
99. Dibble J.B., Sheridan P., Losowsky M.S. A survey of vitamin D deficiency in gastrointestinal and liver disorders. Q. J. Med. 1984, 209:119-134.
100. Imawari M., Kozawa K., Akanuma Y., Koizumi S., Itakura H., Kosaka K. Serum 25-hydroxyvitamin D and vitamin D-binding protein levels and mineral metabolism after partial and total gastrectomy. Gastroenterology 1980, 79:255-258.
101. Bikle D.D., Gee E., Halloran B., Kowalski M.A., Ryzen E., Haddad J.G. Assessment of the free fraction of 25-hydroxyvitamin D in serum and its regulation by albumin and the vitamin D-binding protein. J. Clin. Endocrinol. Metab. 1986, 63:954-959.
102. Baek K.H., Jeon H.M., Lee S.S., Lim D.J., Oh K.W., Lee W.Y., et al. Short-term changes in bone and mineral metabolism following gastrectomy in gastric cancer patients. Bone 2008, 42:61-67.
103. Nilsson B.E. Conditions contributing to fracture of the femoral neck. Acta Chirurgica Scandinavica 1970, 136:383-384.
104. Chalmers J., Conacher W.D., Gardner D.L., Scott P.J. Osteomalacia - a common disease in elderly women. J. Bone Joint Surg. 1967, 49:403-423.
105. Compston J.E., Chadha S., Horton W.L., Merrett A.L. Post-gastrectomy osteomalacia. Gut 1980, 21:A904.
106. Gertner J.M., Lilburn M., Domenech M. 25-Hydroxycholecalciferol absorption in steatorrhoea and postgastrectomy osteomalacia. BMJ 1977, 1:1310-1312.
107. Thompson G.R., Lewis B., Booth C.C. Vitamin-D absorption after partial gastrectomy. Lancet 1966, 1:457-458.
108. Stamp T.C. Intestinal absorption of 25-hydroxycholecalciferol. Lancet 1974, 2:121-123.
109. Caniggia A., Gennari C., Cesari L. Intestinal absorption of 45ca dynamics of 45ca in gastrectomy osteoporosis. Acta. Medica Scandinavica 1964, 176:599-605.
110. Harvald B., Krogsgaard A.R., Lous P. Calcium deficiency following partial gastrectomy. Acta. Medica Scandinavica 1962, 172:497-503.
111. Ekbom K., Hed R. Calcium studies in partially gastrectomized patients, with special reference to the oral intake of calcium. Acta. Medica Scandinavica 1965, 178:193-201.
112. Yang Y.X., Lewis J.D., Epstein S., Metz D.C. Long-term proton pump inhibitor therapy and risk of hip fracture. JAMA 2006, 296:2947-2953.
113. Bo-Linn G.W., Davis G.R., Buddrus D.J., Morawski S.G., Santa Ana C., Fordtran J.S. An evaluation of the importance of gastric acid secretion in the absorption of dietary calcium. J. Clin. Invest. 1984, 73:640-647.
114. Recker R.R. Calcium absorption and achlorhydria. N. Engl. J. Med. 1985, 313:70-73.
115. Tougaard L., Rickers H., Rodbro P., Thaysen E.H., Christensen M.S., Lund B., et al. Bone composition and vitamin D after Polya gastrectomy. Acta Medica Scandinavica 1977, 202:47-50.
116. Alhava E.M., Aukee S., Juuti M., Karjalainen P., Kettunen K. The effect of vitamin D2 treatment on bone mineral after partial gastrectomy. Scand. J. Gastroenterol. 1977, 12:497-499.
117. Green P.H., Jabri B. Celiac disease. Ann. Rev. Med. 2006, 57:207-221.
118. Armagan O., Uz T., Tascioglu F., Colak O., Oner C., Akgun Y. Serological screening for celiac disease in premenopausal women with idiopathic osteoporosis. Clin. Rheumatol. 2005, 24:239-243.
119. Stenson W.F., Newberry R., Lorenz R., Baldus C., Civitelli R. Increased prevalence of celiac disease and need for routine screening among patients with osteoporosis. Arch. Intern. Med. 2005, 165:393-399.
120. Mora S., Weber G., Barera G., Bellini A., Pasolini D., Prinster C., et al. Effect of gluten-free diet on bone mineral content in growing patients with celiac disease. Am. J. Clin. Nutr. 1993, 57:224-228.
121. Molteni N., Caraceni M.P., Bardella M.T., Ortolani S., Gandolini G.G., Bianchi P. Bone mineral density in adult celiac patients and the effect of gluten-free diet from childhood. Am. J. Gastroenterol. 1990, 85:51-53.
122. Caraceni M.P., Molteni N., Bardella M.T., Ortolani S., Nogara A., Bianchi P.A. Bone and mineral metabolism in adult celiac disease. Am. J. Gastroenterol. 1988, 83:274-277.
123. Melvin K.E., Hepner G.W., Bordier P., Neale G., Joplin G.F. Calcium metabolism and bone pathology in adult coeliac disease. Q. J. Med. 1970, 39:83-113.
124. Kemppainen T., Kroger H., Janatuinen E., Arnala I., Kosma V.M., Pikkarainen P., et al. Osteoporosis in adult patients with celiac disease. Bone 1999, 24:249-255.
125. Gonzalez D., Mazure R., Mautalen C., Vazquez H., Bai J. Body composition and bone mineral density in untreated and treated patients with celiac disease. Bone 1995, 16:231-234.
126. Mazure R., Vazquez H., Gonzalez D., Mautalen C., Pedreira S., Boerr L., et al. Bone mineral affection in asymptomatic adult patients with celiac disease. Am. J. Gastroenterol. 1994, 89:2130-2134.
127. Exner G.U., Sacher M., Shmerling D.H., Prader A. Growth retardation and bone mineral status in children with coeliac disease recognized after the age of 3 years. Helvetica Paediatrica Acta 1978, 33:497-507.
128. Valdimarsson T., Toss G., Ross I., Lofman O., Strom M. Bone mineral density in coeliac disease. Scand. J. Gastroenterol. 1994, 29:457-461.
129. Bode S., Hassager C., Gudmand-Hoyer E., Christiansen C. Body composition and calcium metabolism in adult treated coeliac disease. Gut 1991, 32:1342-1345.
130. Lindh E., Ljunghall S., Larsson K., Lavo B. Screening for antibodies against gliadin in patients with osteoporosis. J. Intern. Med. 1992, 231:403-406.
131. Drummond F.J., Annis P., O'Sullivan K., Wynne F., Daly M., Shanahan F., et al. Screening for asymptomatic celiac disease among patients referred for bone densitometry measurement. Bone 2003, 33:970-974.
132. Juergens J.L., Scholz D.A., Wollaeger E.E. Severe osteomalacia associated with occult steatorrhea due to nontropical sprue; report of five cases. AMA 1956, 98:774-782.
133. Moss A.J., Waterhouse C., Terry R. Gluten-sensitive enteropathy with osteomalacia but without steatorrhea. N. Engl. J. Med. 1965, 272:825-830.
134. Salvesen H.A., Boe J. Osteomalacia in sprue. Acta Medica Scandinavica 1953, 146:290-299.
135. Janatuinen E., Alhava E., Arnala I., Julkunen R., Kosma V.M., Kroger H., et al. Bone density and histomorphometry in adult coeliac disease. Gastroenterology 1992, 102:229.
136. Corazza G.R., Di Sario A., Cecchetti L., Jorizzo R.A., Di Stefano M., Minguzzi L., et al. Influence of pattern of clinical presentation and of gluten-free diet on bone mass and metabolism in adult coeliac disease. Bone 1996, 18:525-530.
137. Arnaud S.B., Newcomer A.D., Dickson E.R., Arnaud C.D., Go L.W.V. Altered mineral metabolism in patients with gastrointestinal (GI) diseases. Gastroenterology 1976, 70:860.
138. Davie M.W., Gaywood I., George E., Jones P.W., Masud T., Price T., et al. Excess non-spine fractures in women over 50 years with celiac disease: a cross-sectional, questionnaire-based study. Osteoporos. Int. 2005, 16:1150-1155.
139. Vestergaard P., Mosekilde L. Fracture risk in patients with celiac disease, Crohn's disease, and ulcerative colitis: a nationwide follow-up study of 16,416 patients in Denmark. Am. J. Epidemiol. 2002, 156:1-10.
140. Collin P., Kaukinen K., Valimaki M., Salmi J. Endocrinological disorders and celiac disease. Endocr. Rev. 2002, 23:464-483.
141. Bernstein C.N., Leslie W.D. The pathophysiology of bone disease in gastrointestinal disease. Eur. J. Gastroenterol. Hepatol. 2003, 15:857-864.
142. Jansson U.H., Kristiansson B., Magnusson P., Larsson L., Albertsson-Wikland K., Bjarnason R. The decrease of IGF-I, IGF-binding protein-3 and bone alkaline phosphatase isoforms during gluten challenge correlates with small intestinal inflammation in children with coeliac disease. Eur. J. Endocrinol./Eur. Fed. Endocr. Soc. 2001, 144:417-423.
143. Hepner G.W., Jowsey J., Arnaud C., Gordon S., Black J., Roginsky M., et al. Osteomalacia and celiac disease: response to 25-hydroxyvitamin D. Am. J. Med. 1978, 65:1015-1020.
144. Compston J.E., Judd D., Crawley E.O., Evans W.D., Evans C., Church H.A., et al. Osteoporosis in patients with inflammatory bowel disease. Gut 1987, 28:410-415.
145. Bernstein C.N., Seeger L.L., Sayre J.W., Anton P.A., Artinian L., Shanahan F. Decreased bone density in inflammatory bowel disease is related to corticosteroid use and not disease diagnosis. J. Bone Miner. Res. 1995, 10:250-256.
146. Greenstein A.J., Janowitz H.D., Sachar D.B. The extra-intestinal complications of Crohn's disease and ulcerative colitis: a study of 700 patients. Medicine 1976, 55:401-412.
147. Cooke W.T. Survey of results of treatment of Crohn's disease. Clin. Gastroenterol. 1972, 1:521-531.
148. Driscoll R.H., Meredith S.C., Sitrin M., Rosenberg I.H. Vitamin D deficiency and bone disease in patients with Crohn's disease. Gastroenterology 1982, 83:1252-1258.
149. Compston J.E., Ayers A.B., Horton L.W., Tighe J.R., Creamer B. Osteomalacia after small-intestinal resection. Lancet 1978, 1:9-12.
150. Ward L.M., Rauch F., Matzinger M.A., Benchimol E.I., Boland M., Mack D.R. Iliac bone histomorphometry in children with newly diagnosed inflammatory bowel disease. Osteoporos. Int. 2010, 21:331-337.
151. Issenman R.M., Atkinson S.A., Radoja C., Fraher L. Longitudinal assessment of growth, mineral metabolism, and bone mass in pediatric Crohn's disease. J. Pediatr. Gastroenterol. Nutr. 1993, 17:401-406.
152. Sitrin M., Meredith S., Rosenberg I.H. Vitamin D deficiency and bone disease in gastrointestinal disorders. Arch. Intern. Med. 1978, 138:886-888.
153. Scharla S.H., Minne H.W., Lempert U.G., Leidig G., Hauber M., Raedsch R., et al. Bone mineral density and calcium regulating hormones in patients with inflammatory bowel disease (Crohn's disease and ulcerative colitis). Exp. Clin. Endocrinol. 1994, 102:44-49.
154. Eivindson M., Gronbaek H., Flyvbjerg A., Frystyk J., Zimmermann-Nielsen E., Dahlerup J.F. The insulin-like growth factor (IGF)-system in active ulcerative colitis and Crohn's disease: relations to disease activity and corticosteroid treatment. Growth Horm. IGF Res. 2007, 17:33-40.
155. Pappa H.M., Gordon C.M., Saslowsky T.M., Zholudev A., Horr B., Shih M.C., et al. Vitamin D status in children and young adults with inflammatory bowel disease. Pediatrics 2006, 118:1950-1961.
156. Abreu M.T., Kantorovich V., Vasiliauskas E.A., Gruntmanis U., Matuk R., Daigle K., et al. Measurement of vitamin D levels in inflammatory bowel disease patients reveals a subset of Crohn's disease patients with elevated 1,25-dihydroxyvitamin D and low bone mineral density. Gut 2004, 53:1129-1136.
157. Hessov I., Mosekilde L., Melsen F., Fasth S., Hulten L., Lund B., et al. Osteopenia with normal vitamin D metabolites after small-bowel resection for Crohn's disease. Scand J. Gastroenterol. 1984, 19:691-696.
158. Krawitt E.L., Beeken W.L., Janney C.D. Calcium absorption in Crohn's disease. Gastroenterology 1976, 71:251-254.
159. Avioli L.V. Absorption and metabolism of vitamin D3 in man. Am. J. Clin. Nutr. 1969, 22:437-446.
160. DiFedele L.M., He J., Bonkowski E.L., Han X., Held M.A., Bohan A., et al. Tumor necrosis factor alpha blockade restores growth hormone signaling in murine colitis. Gastroenterology 2005, 128:1278-1291.
161. Cannizzo F., Kral J.G. Obesity surgery: a model of programmed undernutrition. Curr. Opin. Clin. Nutr. Metab. Care 1998, 1:363-368.
162. Sellin J.H., Meredith S.C., Kelly S., Schneir H., Rosenberg I.H. Prospective evaluation of metabolic bone disease after jejunoileal bypass. Gastroenterology 1984, 87:123-129.
163. Teitelbaum S.L., Halverson J.D., Bates M., Wise L., Haddad J.G. Abnormalities of circulating 25-OH vitamin D after jejunal-ileal bypass for obesity: evidence of an adaptive response. Ann. Intern. Med. 1977, 86:289-293.
164. Rickers H., Christiansen C., Balslev I., Foltved H., Rodbro P., Christensen M.S. Vitamin D and bone mineral content after intestinal bypass operation for obesity. Gut 1983, 24:67-72.
165. Rickers H., Christiansen C., Balslev I., Rodbro P. Impairment of vitamin D metabolism and bone mineral content after intestinal bypass for obesity. A longitudinal study. Scand. J. Gastroenterol. 1984, 19:184-189.
166. Compston J.E., Horton L.W., Laker M.F., Ayers A.B., Woodhead J.S., Bull H.J., et al. Bone disease after jejuno-ileal bypass for obesity. Lancet 1978, 2:1-4.
167. Mosekilde L., Melsen F., Hessov I., Christensen M.S., Lund B.J., Lund B.I., et al. Low serum levels of 1.25-dihydroxyvitamin D and histomorphometric evidence of osteomalacia after jejunoileal bypass for obesity. Gut 1980, 21:624-631.
168. Parfitt A.M., Podenphant J., Villanueva A.R., Frame B. Metabolic bone disease with and without osteomalacia after intestinal bypass surgery: a bone histomorphometric study. Bone 1985, 6:211-220.
169. Melsen F., Mosekilde L. Trabecular bone mineralization lag time determined by tetracycline double-labeling in normal and certain pathological conditions. Acta Pathologica Microbiologica Scandinavica 1980, 88:83-88.
170. Gilmore I.T., Eastwood J.B., Ellis W.R., Luck V.A., Fenton S., O'Grady A.J., et al. Bone disease after jejuno-ileal bypass for morbid obesity. Postgrad. Med. J. 1983, 59:299-303.
171. Newbury L., Dolan K., Hatzifotis M., Low N., Fielding G. Calcium and vitamin D depletion and elevated parathyroid hormone following biliopancreatic diversion. Obes. Surg. 2003, 13:893-895.
172. Tsiftsis D.D., Mylonas P., Mead N., Kalfarentzos F., Alexandrides T.K. Bone mass decreases in morbidly obese women after long limb-biliopancreatic diversion and marked weight loss without secondary hyperparathyroidism. A physiological adaptation to weight loss?. Obes. Surg. 2009, 19:1497-1503.
173. Fleischer J., Stein E.M., Bessler M., Della Badia M., Restuccia N., Olivero-Rivera L., et al. The decline in hip bone density after gastric bypass surgery is associated with extent of weight loss. J. Clin. Endocrinol. Metab. 2008, 93:3735-3740.
174. Bruno C., Fulford A.D., Potts J.R., McClintock R., Jones R., Cacucci B.M., et al. Serum markers of bone turnover are increased at six and 18 months after Roux-en-Y bariatric surgery: correlation with the reduction in leptin. J. Clin. Endocrinol. Metab. 2010, 95:159-166.
175. Ensrud K.E., Ewing S.K., Stone K.L., Cauley J.A., Bowman P.J., Cummings S.R. Intentional and unintentional weight loss increase bone loss and hip fracture risk in older women. J. Am. Geriatr. Soc. 2003, 51:1740-1747.
176. Dano P., Christiansen C. Calcium absorption and bone mineral contents following intestinal shunt operation in obesity. Scand. J. Gastroenterol. 1974, 9:775-779.
177. Hey H., Stokholm K.H., Lund B., Lund B., Sorensen O.H. Vitamin D deficiency in obese patients and changes in circulating vitamin D
178. DiGiorgi M., Daud A., Inabnet W.B., Schrope B., Urban-Skuro M., Restuccia N., et al. Markers of bone and calcium metabolism following gastric bypass and laparoscopic adjustable gastric banding. Obes. Surg. 2008, 18:1144-1148.
179. Bell N.H. Bone loss and gastric bypass surgery for morbid obesity. J. Clin. Endocrinol. Metab. 2004, 89:1059-1060.
180. Charles P., Mosekilde L., Sondergard K., Jensen F.T. Treatment with high-dose oral vitamin D2 in patients with jejunoileal bypass for morbid obesity. Effects on calcium and magnesium metabolism, vitamin D metabolites, and faecal lag time. Scand. J. Gastroenterol. 1984, 19:1031-1038.
181. Franck W.A., Hoffman G.S., Davis J.S., Alpern H.D., Olson J.E. Osteomalacia and weakness complicating jejunoileal bypass. J. Rheumatol. 1979, 6:51-56.
182. Brasitus T.A., Sitrain M.D. Intestinal malabsorption syndromes. Ann. Rev. Med. 1990, 41:339-347.
183. Hey H., Lund B., Sorensen O.H., Lund B. Delayed fracture healing following jejunoileal bypass surgery for obesity. Calcif. Tissue Int. 1982, 34:13-15.
184. Friedman H.Z., Langman C.B., Favus M.J. Vitamin D metabolism and osteomalacia in cystic fibrosis. Gastroenterology 1985, 88:808-813.
185. Mann S.T., Stracke H., Lange U., Klor H.U., Teichmann J. Alterations of bone mineral density and bone metabolism in patients with various grades of chronic pancreatitis. Metabolism 2003, 52:579-585.
186. Assan R., Alexandre J.H., Tiengo A., Marre M., Costamailleres L., Lhomme C. Survival and rehabilitation after total pancreatectomy. A follow-up of 36 patients. Diabetes Metabolism 1985, 11:303-309.
187. Hahn T.J., Squires A.E., Halstead L.R., Strominger D.B. Reduced serum 25-hydroxyvitamin D concentration and disordered mineral metabolism in patients with cystic fibrosis. J. Pediatr. 1979, 94:38-42.
188. Stead R.J., Houlder S., Agnew J., Thomas M., Hodson M.E., Batten J.C., et al. Vitamin D and parathyroid hormone and bone mineralisation in adults with cystic fibrosis. Thorax 1988, 43:190-194.
189. Bachrach L.K., Loutit C.W., Moss R.B. Osteopenia in adults with cystic fibrosis. Am. J. Med. 1994, 96:27-34.
190. Aris R.M., Renner J.B., Winders A.D., Buell H.E., Riggs D.B., Lester G.E., et al. Increased rate of fractures and severe kyphosis: sequelae of living into adulthood with cystic fibrosis. Ann. Intern. Med. 1998, 128:186-193.
191. Grey V., Atkinson S., Drury D., Casey L., Ferland G., Gundberg C., et al. Prevalence of low bone mass and deficiencies of vitamins D and K in pediatric patients with cystic fibrosis from 3 Canadian centers. Pediatrics 2008, 122:1014-1020.
192. Aris R.M., Merkel P.A., Bachrach L.K., Borowitz D.S., Boyle M.P., Elkin S.L., et al. Guide to bone health and disease in cystic fibrosis. J. Clin. Endocrinol. Metab. 2005, 90:1888-1896.
193. Rossini M., Del Marco A., Dal Santo F., Gatti D., Braggion C., James G., et al. Prevalence and correlates of vertebral fractures in adults with cystic fibrosis. Bone 2004, 35:771-776.
194. Compston J.E., Vedi S., Gianetta E., Watson G., Civalleri D., Scopinaro N. Bone histomorphometry and vitamin D status after biliopancreatic bypass for obesity. Gastroenterology 1984, 87:350-356.
195. Scott J., Elias E., Moult P.J., Barnes S., Wills M.R. Rickets in adult cystic fibrosis with myopathy, pancreatic insufficiency and proximal renal tubular dysfunction. Am. J. Med. 1977, 63:488-492.
196. Haworth C.S., Selby P.L., Webb A.K., Martin L., Elborn J.S., Sharples L.D., et al. Inflammatory related changes in bone mineral content in adults with cystic fibrosis. Thorax 2004, 59:613-617.
197. Hillman L.S., Cassidy J.T., Popescu M.F., Hewett J.E., Kyger J., Robertson J.D. Percent true calcium absorption, mineral metabolism, and bone mineralization in children with cystic fibrosis: effect of supplementation with vitamin D and calcium. Pediatr. Pulmonol. 2008, 43:772-780.
198. Boyle M.P., Noschese M.L., Watts S.L., Davis M.E., Stenner S.E., Lechtzin N. Failure of high-dose ergocalciferol to correct vitamin D deficiency in adults with cystic fibrosis. Am. J. Resp. Crit. Care Med. 2005, 172:212-217.
199. Long R.G., Meinhard E., Skinner R.K., Varghese Z., Wills M.R., Sherlock S. Clinical, biochemical, and histological studies of osteomalacia, osteoporosis, and parathyroid function in chronic liver disease. Gut 1978, 19:85-90.
200. Davies M., Mawer E.B., Klass H.J., Lumb G.A., Berry J.L., Warnes T.W. Vitamin D deficiency, osteomalacia, and primary biliary cirrhosis. Response to orally administered vitamin D3. Digest Dis. Sci. 1983, 28:145-153.
201. Stellon A.J., Webb A., Compston J., Williams R. Low bone turnover state in primary biliary cirrhosis. Hepatology 1987, 7:137-142.
202. Matloff D.S., Kaplan M.M., Neer R.M., Goldberg M.J., Bitman W., Wolfe H.J. Osteoporosis in primary biliary cirrhosis: effects of 25-hydroxyvitamin D3 treatment. Gastroenterology 1982, 83:97-102.
203. Herlong H.F., Recker R.R., Maddrey W.C. Bone disease in primary biliary cirrhosis: histologic features and response to 25-hydroxyvitamin D. Gastroenterology 1982, 83:103-108.
204. Atkinson M.J., Vido I., Keck E., Hesch R.D. Hepatic osteodystrophy in primary biliary cirrhosis: a possible defect in Kupffer cell mediated cleavage of parathyroid hormone. Clin. Endocrinol. (Oxf.) 1983, 19:21-28.
205. Bengoa J.M., Sitrin M.D., Meredith S., Kelly S.E., Shah N., Baker A.L., et al. Intestinal calcium absorption and vitamin D status in chronic cholestatic liver disease. Hepatology 1984, 4:261-265.
206. Reed J.S., Meredith S.C., Nemchausky B.A., Rosenberg I.H., Boyer J.L. Bone disease in primary biliary cirrhosis: reversal of osteomalacia with oral 25-hydroxyvitamin D. Gastroenterology 1980, 78:512-517.
207. Hodgson S.F., Dickson E.R., Wahner H.W., Johnson K.A., Mann K.G., Riggs B.L. Bone loss and reduced osteoblast function in primary biliary cirrhosis. Ann. Intern. Med. 1985, 103:855-860.
208. Mitchison H.C., Malcolm A.J., Bassendine M.F., James O.F. Metabolic bone disease in primary biliary cirrhosis at presentation. Gastroenterology 1988, 94:463-470.
209. Cuthbert J.A., Pak C.Y., Zerwekh J.E., Glass K.D., Combes B. Bone disease in primary biliary cirrhosis: increased bone resorption and turnover in the absence of osteoporosis or osteomalacia. Hepatology 1984, 4:1-8.
210. Shih M.S., Anderson C. Does "hepatic osteodystrophy" differ from peri- and postmenopausal osteoporosis? A histomorphometric study. Calcif. Tissue Int. 1987, 41:187-191.
211. Diamond T., Stiel D., Lunzer M., Wilkinson M., Roche J., Posen S. Osteoporosis and skeletal fractures in chronic liver disease. Gut 1990, 31:82-87.
212. Guichelaar M.M., Malinchoc M., Sibonga J., Clarke B.L., Hay J.E. Bone metabolism in advanced cholestatic liver disease: analysis by bone histomorphometry. Hepatology 2002, 36:895-903.
213. Gasser R.W. Cholestasis and metabolic bone disease - a clinical review. Wiener Medizinische Wochenschrift (1946) 2008, 158:553-557.
214. Long R.G., Sherlock S. Vitamin D in chronic liver disease. Prog. Liver Dis. 1979, 6:539-555.
215. Heaf J.G. Hepatic osteodystrophy. Scand. J. Gastroenterol. 1985, 20:1035-1040.
216. Griffin J.B., Smith C.D., Bright G.M. Bone disease in biliary atresia: a not uncommon complication. Curr. Surg. 1985, 42:475-477.
217. Guanabens N., Pares A., Marinoso L., Brancos M.A., Piera C., Serrano S., et al. Factors influencing the development of metabolic bone disease in primary biliary cirrhosis. Am. J. Gastroenterol. 1990, 85:1356-1362.
218. Van Berkum F.N., Beukers R., Birkenhager J.C., Kooij P.P., Schalm S.W., Pols H.A. Bone mass in women with primary biliary cirrhosis: the relation with histological stage and use of glucocorticoids. Gastroenterology 1990, 99:1134-1139.
219. Fonseca V., Epstein O., Gill D.S., Menon R.K., Thomas M., McIntyre N., et al. Hyperparathyroidism and low serum osteocalcin despite vitamin D replacement in primary biliary cirrhosis. J. Clin. Endocrinol. Metab. 1987, 64:873-877.
220. Hodgson S.F., Dickson E.R., Eastell R., Eriksen E.F., Bryant S.C., Riggs B.L. Rates of cancellous bone remodeling and turnover in osteopenia associated with primary biliary cirrhosis. Bone 1993, 14:819-827.
221. Long R.G., Skinner R.K., Wills M.R., Sherlock S. Serum-25-hydroxy-vitamin-D in untreated parenchymal and cholestatic liver disease. Lancet 1976, 2:650-652.
222. Kaplan M.M., Goldberg M.J., Matloff D.S., Neer R.M., Goodman D.B. Effect of 25-hydroxyvitamin D3 on vitamin D metabolites in primary biliary cirrhosis. Gastroenterology 1981, 81:681-685.
223. Stellon A.J., Davies A., Compston J., Williams R. Osteoporosis in chronic cholestatic liver disease. Q. J. Med. 1985, 57:783-790.
224. Danielsson A., Lorentzon R., Larsson S.E. Intestinal absorption and 25-hydroxylation of vitamin D in patients with primary biliary cirrhosis. Scand. J. Gastroenterol. 1982, 17:349-355.
225. Solaymani-Dodaran M., Card T.R., Aithal G.P., West J. Fracture risk in people with primary biliary cirrhosis: a population-based cohort study. Gastroenterology 2006, 131:1752-1757.
226. Holda M.E., Ryan J.R. Hepatobiliary rickets. J. Pediatr. Orthop. 1982, 2:285-287.
227. Kehayoglou A.K., Holdsworth C.D., Agnew J.E., Whelton M.J., Sherlock S. Bone disease and calcium absorption in primary biliary cirrhosis with special reference to vitamin-D therapy. Lancet 1968, 1:715-718.
228. Long R.G., Varghese Z., Wills M.R., Sherlock S. Plasma calcium and magnesium fractions in liver disease. Clinica Chimica Acta. Int. J. Clin. Chem. 1978, 84:239-245.
229. Sitrin M.D., Bengoa J.M. Intestinal absorption of cholecalciferol and 25-hydroxycholecalciferol in chronic cholestatic liver disease. Am. J. Clin. Nutr. 1987, 46:1011-1015.
230. Thompson W.G., Thompson G.R. Effect of cholestyramine on the absorption of vitamin D3 and calcium. Gut 1969, 10:717-722.
231. Skinner R.K., Sherlock S., Long R.G., Wilis M.R. 25-Hydroxylation of vitamin D in primary biliary cirrhosis. Lancet 1977, 1:720-721.
232. Mawer E.B., Klass H.J., Warnes T.W., Berry J.L. Metabolism of vitamin D in patients with primary biliary cirrhosis and alcoholic liver disease. Clin. Sci. (Lond.) 1985, 69:561-570.
233. Long R.G. Hepatic osteodystrophy: outlook good but some problems unsolved. Gastroenterology 1980, 78:644-647.
234. Epstein O., Kato Y., Dick R., Sherlock S. Vitamin D, hydroxyapatite, and calcium gluconate in treatment of cortical bone thinning in postmenopausal women with primary biliary cirrhosis. Am. J. Clin. Nutr. 1982, 36:426-430.
235. Porayko M.K., Wiesner R.H., Hay J.E., Krom R.A., Dickson E.R., Beaver S., et al. Bone disease in liver transplant recipients: incidence, timing, and risk factors. Transplant. Proc. 1991, 23:1462-1465.
236. Stellon A.J., Davies A., Compston J., Williams R. Bone loss in autoimmune chronic active hepatitis on maintenance corticosteroid therapy. Gastroenterology 1985, 89:1078-1083.
237. Dibble J.B., Sheridan P., Hampshire R., Hardy G.J., Losowsky M.S. Osteomalacia, vitamin D deficiency and cholestasis in chronic liver disease. Q. J. Med. 1982, 51:89-103.
238. Saron M.L., Godoy H.T., Hessel G. Nutritional status of patients with biliary atresia and autoimmune hepatitis related to serum levels of vitamins A, D and E. Arquivos Gastroenterologia 2009, 46:62-68.
239. Gonzalez-Calvin J.L., Gallego-Rojo F., Fernandez-Perez R., Casado-Caballero F., Ruiz-Escolano E., Olivares E.G. Osteoporosis, mineral metabolism, and serum soluble tumor necrosis factor receptor p55 in viral cirrhosis. J. Clin. Endocrinol. Metab. 2004, 89:4325-4330.
240. Gonzalez-Calvin J.L., Mundi J.L., Casado-Caballero F.J., Abadia A.C., Martin-Ibanez J.J. Bone mineral density and serum levels of soluble tumor necrosis factors, estradiol, and osteoprotegerin in postmenopausal women with cirrhosis after viral hepatitis. J. Clin. Endocrinol. Metab. 2009, 94:4844-4850.
241. Gallego-Rojo F.J., Gonzalez-Calvin J.L., Munoz-Torres M., Mundi J.L., Fernandez-Perez R., Rodrigo-Moreno D. Bone mineral density, serum insulin-like growth factor I, and bone turnover markers in viral cirrhosis. Hepatology 1998, 28:695-699.
242. Fisher L., Byrnes E., Fisher A.A. Prevalence of vitamin K and vitamin D deficiency in patients with hepatobiliary and pancreatic disorders. Nutri. Res. (NY) 2009, 29:676-683.
243. Whyte M.P., Teitelbaum S.L., Reinus W.R. Doubling skeletal mass during adult life: the syndrome of diffuse osteosclerosis after intravenous drug abuse. J. Bone Miner. Res. 1996, 11:554-558.
244. Diamond T., Depczynski B. Acquired osteosclerosis associated with intravenous drug use and hepatitis C infection. Bone 1996, 19:679-683.
245. Hassoun A.A., Nippoldt T.B., Tiegs R.D., Khosla S. Hepatitis C-associated osteosclerosis: an unusual syndrome of acquired osteosclerosis in adults. Am. J. Med. 1997, 103:70-73.
246. Shiomi S., Masaki K., Habu D., Takeda T., Nishiguchi S., Kuroki T., et al. Calcitriol for bone disease in patients with cirrhosis of the liver. J. Gastroenterol. Hepatol. 1999, 14:547-552.
247. Saville P.D. Changes in bone mass with age and alcoholism. J. Bone Joint. Surg. Am. 1965, 47:492-499.
248. Spencer H., Rubio N., Rubio E., Indreika M., Seitam A. Chronic alcoholism. Frequently overlooked cause of osteoporosis in men. Am. J. Med. 1986, 80:393-397.
249. Lindsell D.R., Wilson A.G., Maxwell J.D. Fractures on the chest radiograph in detection of alcoholic liver disease. BMJ (Clinical Research ed.) 1982, 285:597-599.
250. Israel Y., Orrego H., Holt S., Macdonald D.W., Meema H.E. Identification of alcohol abuse: thoracic fractures on routine chest X-rays as indicators of alcoholism. Alcohol, Clin. Exp. Res. 1980, 4:420-422.
251. Odvina C.V., Safi I., Wojtowicz C.H., Barengolts E.I., Lathon P., Skapars A., et al. Effect of heavy alcohol intake in the absence of liver disease on bone mass in black and white men. J. Clin. Endocrinol. Metab. 1995, 80:2499-2503.
252. Bikle D.D., Stesin A., Halloran B., Steinbach L., Recker R. Alcohol-induced bone disease: relationship to age and parathyroid hormone levels. Alcohol, Clin. Exp. Res. 1993, 17:690-695.
253. Nilsson B.E., Westlin N.E. Femur density in alcoholism and after gastrectomy. Calcif. Tissue Res. 1972, 10:167-170.
254. Nilsson B.E., Westlin N.E. Changes in bone mass in alcoholics. Clin. Orthop. Rel. Res. 1973, 229-232.
255. Bikle D.D., Genant H.K., Cann C., Recker R.R., Halloran B.P., Strewler G.J. Bone disease in alcohol abuse. Ann. Intern. Med. 1985, 103:42-48.
256. de Vernejoul M.C., Bielakoff J., Herve M., Gueris J., Hott M., Modrowski D., et al. Evidence for defective osteoblastic function. A role for alcohol and tobacco consumption in osteoporosis in middle-aged men. Clin. Orthop. Rel. Res. 1983, 107-115.
257. Jorge-Hernandez J.A., Gonzalez-Reimers C.E., Torres-Ramirez A., Santolaria-Fernandez F., Gonzalez-Garcia C., Batista-Lopez J.N., et al. Bone changes in alcoholic liver cirrhosis. A histomorphometrical analysis of 52 cases. Digest. Dis. Sci. 1988, 33:1089-1095.
258. Schnitzler C.M., Solomon L. Bone changes after alcohol abuse. South African Medical Journal 1984, 66:730-734.
259. Mobarhan S.A., Russell R.M., Recker R.R., Posner D.B., Iber F.L., Miller P. Metabolic bone disease in alcoholic cirrhosis: a comparison of the effect of vitamin D2, 25-hydroxyvitamin D, or supportive treatment. Hepatology 1984, 4:266-273.
260. Lalor B.C., France M.W., Powell D., Adams P.H., Counihan T.B. Bone and mineral metabolism and chronic alcohol abuse. Q. J. Med. 1986, 59:497-511.
261. Arlot M.E., Bonjean M., Chavassieux P.M., Meunier P.J. Bone histology in adults with aseptic necrosis. Histomorphometric evaluation of iliac biopsies in seventy-seven patients. J. Bone Joint. Surg. Am. 1983, 65:1319-1327.
262. Johnell O., Nilsson B.E., Wiklund P.E. Bone morphometry in alcoholics. Clin. Orthop. Rel. Res. 1982, 253-258.
263. Solomon L. Idiopathic necrosis of the femoral head: pathogenesis and treatment. Can. J. Surg. 1981, 24:573-578.
264. Gold E.W., Cangemi P.J. Incidence and pathogenesis of alcohol-induced osteonecrosis of the femoral head. Clin. Orthop. Rel. Res. 1979, 222-226.
265. Pitts T.O., Van Thiel D.H. Disorders of divalent ions and vitamin D metabolism in chronic alcoholism. Recent Dev. Alcohol 1986, 4:357-377.
266. Feitelberg S., Epstein S., Ismail F., D'Amanda C. Deranged bone mineral metabolism in chronic alcoholism. Metabolism 1987, 36:322-326.
267. Laitinen K., Lamberg-Allardt C., Tunninen R., Karonen S.L., Tahtela R., Ylikahri R., et al. Transient hypoparathyroidism during acute alcohol intoxication. N. Engl. J. Med. 1991, 324:721-727.
268. George J., Ganesh H.K., Acharya S., Bandgar T.R., Shivane V., Karvat A., et al. Bone mineral density and disorders of mineral metabolism in chronic liver disease. World J. Gastroenterol. 2009, 15:3516-3522.
269. Roginsky M.S., Zanzi I., Cohn S.H. Skeletal and lean body mass in alcoholics with and without cirrhosis. Calcif. Tissue Res. 1976, 21(Suppl):386-391.
270. Bikle D.D., Halloran B.P., Gee E., Ryzen E., Haddad J.G. Free 25-hydroxyvitamin D levels are normal in subjects with liver disease and reduced total 25-hydroxyvitamin D levels. J. Clin. Invest. 1986, 78:748-752.
271. Bikle D.D., Gee E., Halloran B., Haddad J.G. Free 1,25-dihydroxyvitamin D levels in serum from normal subjects, pregnant subjects, and subjects with liver disease. J. Clin. Invest. 1984, 74:1966-1971.
272. Bikle D.D., Siiteri P.K., Ryzen E., Haddad J.G. Serum protein binding of 1,25-dihydroxyvitamin D: a reevaluation by direct measurement of free metabolite levels. J. Clin. Endocrinol. Metab. 1985, 61:969-975.
273. Leevy C.M., Thompson A., Baker H. Vitamins and liver injury. Am. J. Clin. Nutr. 1970, 23:493-499.
274. Jung R.T., Davie M., Hunter J.O., Chalmers T.M., Lawson D.E. Abnormal vitamin D metabolism in cirrhosis. Gut 1978, 19:290-293.
275. Meyer M., Wechsler S., Shibolet S. Vitamin D: Biochemical, Chemical and Clinical Aspects Related to Calcium Metabolism 1977, 831-833. Walter de Gruyter, Berlin/New York. A.W. Norman, K. Schaeffer, J.W. Coburn, H.F. DeLuca (Eds.).
276. Hepner G.W., Roginsky M., Moo H.F. Abnormal vitamin D metabolism in patients with cirrhosis. Am. J. Digest. Dis. 1976, 21:527-532.
277. Adler A.J., Gudis S., Berlyne G.M. Reduced renal phosphate threshold concentration in alcoholic cirrhosis. Miner. Electrolyte Metab. 1984, 10:63-66.
278. Barragry J.M., Long R.G., France M.W., Wills M.R., Boucher B.J., Sherlock S. Intestinal absorption of cholecalciferol in alcoholic liver disease and primary biliary cirrhosis. Gut 1979, 20:559-564.
279. Lund B., Sorensen O.H., Hilden M., Lund B. The hepatic conversion of vitamin D in alcoholics with varying degrees of liver affection. Acta Medica Scandinavica 1977, 202:221-224.
280. Posner D.B., Russell R.M., Absood S., Connor T.B., Davis C., Martin L., et al. Effective 25-hydroxylation of vitamin D2 in alcoholic cirrhosis. Gastroenterology 1978, 74:866-870.
281. Krawitt E.L. Ethanol inhibits intestinal calcium transport in rats. Nature 1973, 243:88-89.
282. Pascual-Garcia A., Donath A., Courvoisier B., et al. Plasma 25OHD, bone mass densitometry and Ca intestinal absorption deficiency in chronic alcoholism. Vitamin D: Biochemical, Chemical and Clinical Aspects Related to Calcium Metabolism 1977, 819-821. Walter de Gruyter, New York. A.W. Norman, K. Schaefer, J.W. Coburn (Eds.).
283. Diamond T., Stiel D., Lunzer M., Wilkinson M., Posen S. Ethanol reduces bone formation and may cause osteoporosis. Am. J. Med. 1989, 86:282-288.
284. Lindholm J., Steiniche T., Rasmussen E., Thamsborg G., Nielsen I.O., Brockstedt-Rasmussen H., et al. Bone disorder in men with chronic alcoholism: a reversible disease?. J. Clin. Endocrinol. Metab. 1991, 73:118-124.
285. Haagsma E.B., Klompmaker I.J., Verwer R., Slooff M.J. Long-term results after liver transplantation in adults. Scand J. Gastroenterol. (Suppl.) 1991, 188:38-43.
286. Guichelaar M.M., Kendall R., Malinchoc M., Hay J.E. Bone mineral density before and after OLT: long-term follow-up and predictive factors. Liver Transpl. 2006, 12:1390-1402.
287. Haagsma E.B., Thijn C.J., Post J.G., Slooff M.J., Gips C.H. Bone disease after orthotopic liver transplantation. J. Hepatol. 1988, 6:94-100.
288. Vedi S., Greer S., Skingle S.J., Garrahan N.J., Ninkovic M., Alexander G.A., et al. Mechanism of bone loss after liver transplantation: a histomorphometric analysis. J. Bone Miner. Res. 1999, 14:281-287.
289. Crosbie O.M., Freaney R., McKenna M.J., Hegarty J.E. Bone density, vitamin D status, and disordered bone remodeling in end-stage chronic liver disease. Calcif. Tissue Int. 1999, 64:295-300.
290. Hawkins F.G., Leon M., Lopez M.B., Valero M.A., Larrodera L., Garcia-Garcia I., et al. Bone loss and turnover in patients with liver transplantation. Hepato-gastroenterology 1994, 41:158-161.
291. Rabinovitz M., Shapiro J., Lian J., Block G.D., Merkel I.S., Van Thiel D.H. Vitamin D and osteocalcin levels in liver transplant recipients. Is osteocalcin a reliable marker of bone turnover in such cases?. J. Hepatol. 1992, 16:50-55.
292. Eastell R., Dickson E.R., Hodgson S.F., Wiesner R.H., Porayko M.K., Wahner H.W., et al. Rates of vertebral bone loss before and after liver transplantation in women with primary biliary cirrhosis. Hepatology 1991, 14:296-300.
293. Millonig G., Graziadei I.W., Eichler D., Pfeiffer K.P., Finkenstedt G., Muehllechner P., et al. Alendronate in combination with calcium and vitamin D prevents bone loss after orthotopic liver transplantation: a prospective single-center study. Liver Transpl. 2005, 11:960-966.
294. Crawford B.A., Kam C., Pavlovic J., Byth K., Handelsman D.J., Angus P.W., et al. Zoledronic acid prevents bone loss after liver transplantation: a randomized, double-blind, placebo-controlled trial. Ann. Intern. Med. 2006, 144:239-248.
295. Klein G.L., Targoff C.M., Ament M.E., Sherrard D.J., Bluestone R., Young J.H., et al. Bone disease associated with total parenteral nutrition. Lancet 1980, 2:1041-1044.
296. Shike M., Harrison J.E., Sturtridge W.C., Tam C.S., Bobechko P.E., Jones G., et al. Metabolic bone disease in patients receiving long-term total parenteral nutrition. Ann. Intern. Med. 1980, 92:343-350.
297. Klein G.L., Alfrey A.C., Miller N.L., Sherrard D.J., Hazlet T.K., Ament M.E., et al. Aluminum loading during total parenteral nutrition. Am. J. Clin. Nutr. 1982, 35:1425-1429.
298. Ott S.M., Maloney N.A., Klein G.L., Alfrey A.C., Ament M.E., Coburn J.W., et al. Aluminum is associated with low bone formation in patients receiving chronic parenteral nutrition. Ann. Intern. Med. 1983, 98:910-914.
299. Vargas J.H., Klein G.L., Ament M.E., Ott S.M., Sherrard D.J., Horst R.L., et al. Metabolic bone disease of total parenteral nutrition: course after changing from casein to amino acids in parenteral solutions with reduced aluminum content. Am. J. Clin. Nutr. 1988, 48:1070-1078.
300. Lipkin E.W., Ott S.M., Klein G.L. Heterogeneity of bone histology in parenteral nutrition patients. Am. J. Clin. Nutr. 1987, 46:673-680.
301. Shike M., Shils M.E., Heller A., Alcock N., Vigorita V., Brockman R., et al. Bone disease in prolonged parenteral nutrition: osteopenia without mineralization defect. Am. J. Clin. Nutr. 1986, 44:89-98.
302. Foldes J., Rimon B., Muggia-Sullam M., Gimmon Z., Leichter I., Steinberg R., et al. Progressive bone loss during long-term home total parenteral nutrition. Jpen. 1990, 14:139-142.
303. Klein G.L., Horst R.L., Norman A.W., Ament M.E., Slatopolsky E., Coburn J.W. Reduced serum levels of 1 alpha,25-dihydroxyvitamin D during long-term total parenteral nutrition. Ann. Intern. Med. 1981, 94:638-643.
304. Shike M., Sturtridge W.C., Tam C.S., Harrison J.E., Jones G., Murray T.M., et al. A possible role of vitamin D in the genesis of parenteral-nutrition-induced metabolic bone disease. Ann. Intern. Med. 1981, 95:560-568.
305. Klein G.L., Coburn J.W. Metabolic bone disease associated with total parenteral nutrition. Adv. Nutr. Res. 1984, 6:67-92.
306. Sedman A.B., Klein G.L., Merritt R.J., Miller N.L., Weber K.O., Gill W.L., et al. Evidence of aluminum loading in infants receiving intravenous therapy. N. Engl. J. Med. 1985, 312:1337-1343.
307. Milliner D.S., Shinaberger J.H., Shuman P., Coburn J.W. Inadvertent aluminum administration during plasma exchange due to aluminum contamination of albumin-replacement solutions. N. Engl. J. Med. 1985, 312:165-167.
308. Bengoa J.M., Sitrin M.D., Wood R.J., Rosenberg I.H. Amino acid-induced hypercalciuria in patients on total parenteral nutrition. Am. J. Clin. Nutr. 1983, 38:264-269.
309. Bikle D.D. Chapter 49 in Osteoporosis in Gastrointestinal, Pancreatic, and Hepatic Diseases in Osteoporosis 2008, Academic Press. third ed. R. Marcus, D. Feldman, D.A. Nelson, C.J. Rosen (Eds.).