메뉴 건너뛰기




Volumn 270, Issue 4 33-4, 1996, Pages

Transcriptional regulation of hepatic sterol 27-hydroxylase by bile acids

Author keywords

biosynthetic pathways; cholesterol degradation; regulation

Indexed keywords

BILE ACID; CHENODEOXYCHOLIC ACID; CHOLESTEROL 7ALPHA MONOOXYGENASE; CHOLIC ACID; COLESTYRAMINE; DEOXYCHOLIC ACID; LIVER ENZYME; STEROL 27 HYDROXYLASE; UNCLASSIFIED DRUG;

EID: 0029876117     PISSN: 01931857     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpgi.1996.270.4.g646     Document Type: Article
Times cited : (73)

References (38)
  • 1
    • 0024394549 scopus 로고
    • Cloning, structure, and expression of the mitochondrial cytochrome P-450 sterol 26-hydroxylase, a bile acid biosynthetic enzyme
    • Andersson, S., D. L. Davis, H. Dahlbäek, H. Jörnvall, and D. W. Russell. Cloning, structure, and expression of the mitochondrial cytochrome P-450 sterol 26-hydroxylase, a bile acid biosynthetic enzyme. J. Biol. Chem. 264: 8222-8229, 1989.
    • (1989) J. Biol. Chem. , vol.264 , pp. 8222-8229
    • Andersson, S.1    Davis, D.L.2    Dahlbäek, H.3    Jörnvall, H.4    Russell, D.W.5
  • 2
    • 0025045782 scopus 로고
    • Potential bile acid precursors in plasma - Possible indicators of biosynthetic pathways to cholic and chenodeoxycholic acids in man
    • Axelson, M., and J. Sjövall. Potential bile acid precursors in plasma - possible indicators of biosynthetic pathways to cholic and chenodeoxycholic acids in man. J. Steroid Biochem. 36: 631-640, 1990.
    • (1990) J. Steroid Biochem. , vol.36 , pp. 631-640
    • Axelson, M.1    Sjövall, J.2
  • 3
    • 0026551710 scopus 로고
    • Mechanism of degradation of the steroid side chain in the formation of bile acids
    • Björkkem, I. Mechanism of degradation of the steroid side chain in the formation of bile acids. J. Lipid Res. 33: 455-472, 1992.
    • (1992) J. Lipid Res. , vol.33 , pp. 455-472
    • Björkkem, I.1
  • 4
    • 0028068796 scopus 로고
    • Atherosclerosis and sterol 27hydroxylase: Evidence for a role of this enzyme in elimination of cholesterol from human macrophages
    • Björkhem, I., O. Andersson, U. Diczfalusy, B. Sevastik, R. Xiu, C. Duan, and E. Lund. Atherosclerosis and sterol 27hydroxylase: evidence for a role of this enzyme in elimination of cholesterol from human macrophages. Froc. Natl. Acad. Sci. USA91: 8592-8596, 1994.
    • (1994) Froc. Natl. Acad. Sci. USA , vol.91 , pp. 8592-8596
    • Björkhem, I.1    Andersson, O.2    Diczfalusy, U.3    Sevastik, B.4    Xiu, R.5    Duan, C.6    Lund, E.7
  • 5
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford, M. M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72: 248-257, 1976.
    • (1976) Anal. Biochem. , vol.72 , pp. 248-257
    • Bradford, M.M.1
  • 6
    • 0025868097 scopus 로고
    • Characterization of human sterol 27-hydroxylase. A mitochondrial cytochrome P-450 that catalyzes multiple oxidation reactions in bile acid biosynthesis
    • Cali, J. J., and D. W. Russell. Characterization of human sterol 27-hydroxylase. A mitochondrial cytochrome P-450 that catalyzes multiple oxidation reactions in bile acid biosynthesis. J. Biol. Chem. 266: 7774-7778, 1991.
    • (1991) J. Biol. Chem. , vol.266 , pp. 7774-7778
    • Cali, J.J.1    Russell, D.W.2
  • 7
    • 0028278187 scopus 로고
    • Identification and characterization of a putative bile acid-responsive element in cholesterol 7α-hydroxylase gene promoter
    • Chiang, J. Y. L., and D. Stroup. Identification and characterization of a putative bile acid-responsive element in cholesterol 7α-hydroxylase gene promoter. J. Biol. Chern. 269: 17502-17507, 1994.
    • (1994) J. Biol. Chern. , vol.269 , pp. 17502-17507
    • Chiang, J.Y.L.1    Stroup, D.2
  • 8
    • 0026738223 scopus 로고
    • Cloning and 5′-flanking sequence of a rat cholesterol 7α-hydroxylase gene
    • Chiang, J. Y. L., T. P. Yang, and D. P. Wang. Cloning and 5′-flanking sequence of a rat cholesterol 7α-hydroxylase gene. Biochim. Biophys. Acta 1132: 337-339, 1992.
    • (1992) Biochim. Biophys. Acta , vol.1132 , pp. 337-339
    • Chiang, J.Y.L.1    Yang, T.P.2    Wang, D.P.3
  • 10
    • 0027448743 scopus 로고
    • Genomic cloning, sequencing, and analysis of the hamster cholesterol 7α-hydroxylase gene (CYP7)
    • Crestani, M., G. Galli, and J. Y. L. Chiang. Genomic cloning, sequencing, and analysis of the hamster cholesterol 7α-hydroxylase gene (CYP7). Arch. Biochem. Biophys. 306: 451-460, 1993.
    • (1993) Arch. Biochem. Biophys. , vol.306 , pp. 451-460
    • Crestani, M.1    Galli, G.2    Chiang, J.Y.L.3
  • 13
    • 18544396604 scopus 로고
    • Diurnal rhythms of bile acid production in the rat
    • Regulatory Integrates Comp. Physiol. 51
    • Duane, W. C., M. L. Gilberstadt, and D. M. Wiegand. Diurnal rhythms of bile acid production in the rat. Am. J. Physiol. 236 (Regulatory Integrates Comp. Physiol. 51: R175-R179, 1979.
    • (1979) Am. J. Physiol. , vol.236
    • Duane, W.C.1    Gilberstadt, M.L.2    Wiegand, D.M.3
  • 14
    • 0021085009 scopus 로고
    • 26-Hydroxycholesterol: Regulation of hydroxymethylglutaryl-CoA reductase activity in Chinese hamster ovary cell culture
    • Esterman, A. L., H. Baum, N. B. Javitt, and G. J. Darlington. 26-Hydroxycholesterol: regulation of hydroxymethylglutaryl-CoA reductase activity in Chinese hamster ovary cell culture. J. Lipid Res. 24: 1304-1309, 1983.
    • (1983) J. Lipid Res. , vol.24 , pp. 1304-1309
    • Esterman, A.L.1    Baum, H.2    Javitt, N.B.3    Darlington, G.J.4
  • 15
    • 70449158340 scopus 로고
    • A simple method for the isolation and purification of total lipids from animal tissues
    • Folch, J., M. Lees, and G. H. Sloane-Stanley. A simple method for the isolation and purification of total lipids from animal tissues. J. Biol. Chem. 226: 497-509, 1957.
    • (1957) J. Biol. Chem. , vol.226 , pp. 497-509
    • Folch, J.1    Lees, M.2    Sloane-Stanley, G.H.3
  • 16
    • 0023805311 scopus 로고
    • Regulation of bile acid synthesis. II. Effect of bile acid feeding on enzymes regulating hepatic cholesterol and bile acid synthesis in the rat
    • Heuman, D. M., Z. R. Vlahcevic, M. L. Bailey, and P. B. Hylemon. Regulation of bile acid synthesis. II. Effect of bile acid feeding on enzymes regulating hepatic cholesterol and bile acid synthesis in the rat. Hepatohgy 8: 892-897, 1988.
    • (1988) Hepatohgy , vol.8 , pp. 892-897
    • Heuman, D.M.1    Vlahcevic, Z.R.2    Bailey, M.L.3    Hylemon, P.B.4
  • 17
    • 0027242111 scopus 로고
    • Transcriptional regulation of the gene encoding cholesterol 7α-hydroxylase in the rat
    • Hoekman, M. F. M., J. M. J. Rientjes, J. Twisk, R. J. Planta, H. M. G. Princen, and W. H. Mager. Transcriptional regulation of the gene encoding cholesterol 7α-hydroxylase in the rat. Gene 130: 217-223, 1993.
    • (1993) Gene , vol.130 , pp. 217-223
    • Hoekman, M.F.M.1    Rientjes, J.M.J.2    Twisk, J.3    Planta, R.J.4    Princen, H.M.G.5    Mager, W.H.6
  • 18
    • 0026794030 scopus 로고
    • Hormonal regulation of cholesterol 7α-hydroxylase mRNA levels and transcriptional activity in primary rat hepatocyte cultures
    • Hylemon, P. B., E. C. Gurley, R. T. Stravitz, J. S. Litz, W. M. Pandak, J. Y. L. Chiang, and Z. R. Vlahcevic. Hormonal regulation of cholesterol 7α-hydroxylase mRNA levels and transcriptional activity in primary rat hepatocyte cultures. J. Biol. Chem. 267: 16866-16871, 1992.
    • (1992) J. Biol. Chem. , vol.267 , pp. 16866-16871
    • Hylemon, P.B.1    Gurley, E.C.2    Stravitz, R.T.3    Litz, J.S.4    Pandak, W.M.5    Chiang, J.Y.L.6    Vlahcevic, Z.R.7
  • 20
    • 0025269939 scopus 로고
    • Cloning and regulation of cholesterol 7α-hydroxylase, the rate limiting enzyme in bile acid biosynthesis
    • Jelinek, D. F., S. Andersson, C. R. Slaughter, and D. W. Russell. Cloning and regulation of cholesterol 7α-hydroxylase, the rate limiting enzyme in bile acid biosynthesis. J. Biol. Chem. 265: 8190-8197, 1990.
    • (1990) J. Biol. Chem. , vol.265 , pp. 8190-8197
    • Jelinek, D.F.1    Andersson, S.2    Slaughter, C.R.3    Russell, D.W.4
  • 21
    • 0027319083 scopus 로고
    • Cholesterol 7α-hydroxylase: Evidence for transcriptional regulation by cholesterol or metabolic products of cholesterol in the rat
    • Jones, M. P., W. M. Pandak, D. M. Heuman, J. Y. L. Chiang, P. B. Hylemon, and Z. R. Vlahcevic. Cholesterol 7α-hydroxylase: evidence for transcriptional regulation by cholesterol or metabolic products of cholesterol in the rat. J. Lipid Res. 34: 885-892, 1993.
    • (1993) J. Lipid Res. , vol.34 , pp. 885-892
    • Jones, M.P.1    Pandak, W.M.2    Heuman, D.M.3    Chiang, J.Y.L.4    Hylemon, P.B.5    Vlahcevic, Z.R.6
  • 22
    • 0027428137 scopus 로고
    • Circadian transcription of the cholesterol 7α-hydroxylase gene may involve the liver-enriched bZIP protein DBF
    • Lavery, D. J., and U. Schibier. Circadian transcription of the cholesterol 7α-hydroxylase gene may involve the liver-enriched bZIP protein DBF Genes Dev. 7: 1871-1884, 1993
    • (1993) Genes Dev. , vol.7 , pp. 1871-1884
    • Lavery, D.J.1    Schibier, U.2
  • 24
    • 0025353861 scopus 로고
    • Regulation of cholesterol 7α-hydroxylase in the liver. Cloning, sequencing, and regulation of cholesterol 7α-hydroxylase mRNA
    • Li, Y. C., D. P. Wang, and J. Y. L. Chiang. Regulation of cholesterol 7α-hydroxylase in the liver. Cloning, sequencing, and regulation of cholesterol 7α-hydroxylase mRNA. J. Biol. Chem. 265: 12012-12019, 1990.
    • (1990) J. Biol. Chem. , vol.265 , pp. 12012-12019
    • Li, Y.C.1    Wang, D.P.2    Chiang, J.Y.L.3
  • 25
    • 0026590331 scopus 로고
    • Transcriptional regulation of the human cholesterol 7α-hydroxylase gene
    • Molowa, D. T., W. S. Chen, G. M. Cimis, and C. P. Tan. Transcriptional regulation of the human cholesterol 7α-hydroxylase gene. Biochemistry 31:2539-2544, 1992.
    • (1992) Biochemistry , vol.31 , pp. 2539-2544
    • Molowa, D.T.1    Chen, W.S.2    Cimis, G.M.3    Tan, C.P.4
  • 26
    • 0025763167 scopus 로고
    • Structural analysis of the gene encoding rat cholesterol α-hydroxylase, the key enzyme for bile acid biosynthesis
    • Nishimoto, M., O. Gotoh, K. Okuda, and M. Noshiro. Structural analysis of the gene encoding rat cholesterol α-hydroxylase, the key enzyme for bile acid biosynthesis. J. Biol. Chem. 266: 6467-6471, 1991.
    • (1991) J. Biol. Chem. , vol.266 , pp. 6467-6471
    • Nishimoto, M.1    Gotoh, O.2    Okuda, K.3    Noshiro, M.4
  • 27
    • 0027398808 scopus 로고
    • Structure of the gene encoding human liver cholesterol 7α-hydroxylase
    • Nishimoto, M., M. Noshiro, and K. Okuda. Structure of the gene encoding human liver cholesterol 7α-hydroxylase. Biochim. Biophys.Acta 1172:147-150, 1993.
    • (1993) Biochim. Biophys.Acta , vol.1172 , pp. 147-150
    • Nishimoto, M.1    Noshiro, M.2    Okuda, K.3
  • 28
    • 0025366699 scopus 로고
    • Rat liver cholesterol 7α-hydroxylase. Pretranslational regulation for circadian rhythm
    • Noshiro, M., M. Nishimoto, and K. Okuda. Rat liver cholesterol 7α-hydroxylase. Pretranslational regulation for circadian rhythm. J. Biol. Chem. 265: 10036-10041, 1990.
    • (1990) J. Biol. Chem. , vol.265 , pp. 10036-10041
    • Noshiro, M.1    Nishimoto, M.2    Okuda, K.3
  • 29
    • 0025894157 scopus 로고
    • Regulation of cholesterol 7α-hydroxylase mRNA and transcriptional activity by taurocholate and cholesterol in the chronic biliary diverted rat
    • Pandak, W. M., Y. C. Li, J. Y. L. Chiang, E. J. Studer, E. C. Gurley, D. M. Heuman, Z. R. Vlahcevic, and P. B. Hylemon. Regulation of cholesterol 7α-hydroxylase mRNA and transcriptional activity by taurocholate and cholesterol in the chronic biliary diverted rat. J. Biol. Chem. 266: 3416-3421, 1991.
    • (1991) J. Biol. Chem. , vol.266 , pp. 3416-3421
    • Pandak, W.M.1    Li, Y.C.2    Chiang, J.Y.L.3    Studer, E.J.4    Gurley, E.C.5    Heuman, D.M.6    Vlahcevic, Z.R.7    Hylemon, P.B.8
  • 30
    • 0027456308 scopus 로고
    • Synthesis of 27-hydroxycholesterol in rat liver mitochondria: HPLC assay and marked activation by exogenous cholesterol
    • Petrack, B., and B. J. Latario. Synthesis of 27-hydroxycholesterol in rat liver mitochondria: HPLC assay and marked activation by exogenous cholesterol. J. Lipid Res. 34: 643-649, 1993.
    • (1993) J. Lipid Res. , vol.34 , pp. 643-649
    • Petrack, B.1    Latario, B.J.2
  • 31
    • 0025845457 scopus 로고
    • Cyclosporin A blocks bile acid synthesis in cultured hepatocytes by specific inhibition of chenodeoxychohc acid synthesis
    • Princen, H. M. G., P. Meijer, B. G. Wolthers, R. J. Vonk, and F. Kuipers. Cyclosporin A blocks bile acid synthesis in cultured hepatocytes by specific inhibition of chenodeoxychohc acid synthesis. Biochem. J. 275: 501-505, 1991.
    • (1991) Biochem. J. , vol.275 , pp. 501-505
    • Princen, H.M.G.1    Meijer, P.2    Wolthers, B.G.3    Vonk, R.J.4    Kuipers, F.5
  • 34
    • 0026808475 scopus 로고
    • Sequence complementarity between the 5′-terminal regions of mRNAs for rat mitochondrial cytochrome P-450c27/25 and a growth hormone-inducible serine protease inhibitor
    • Shayiq, R. M., and N. G. Avadhani. Sequence complementarity between the 5′-terminal regions of mRNAs for rat mitochondrial cytochrome P-450c27/25 and a growth hormone-inducible serine protease inhibitor. J. Biol. Chem. 267: 2421-2428, 1992.
    • (1992) J. Biol. Chem. , vol.267 , pp. 2421-2428
    • Shayiq, R.M.1    Avadhani, N.G.2
  • 38
    • 0028850779 scopus 로고
    • Suppression of sterol 27-hydroxylase mRNA and transcriptional activity by bile acids in cultured rat hepatocytes
    • Twisk, J., E. C. M. De Wit, and H. M. G. Princen. Suppression of sterol 27-hydroxylase mRNA and transcriptional activity by bile acids in cultured rat hepatocytes. Biochem. J. 305: 505-511. 1995.
    • (1995) Biochem. J. , vol.305 , pp. 505-511
    • Twisk, J.1    De Wit, E.C.M.2    Princen, H.M.G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.