메뉴 건너뛰기




Volumn 8, Issue 9, 2013, Pages

Live Attenuated Rev-Independent Nef-SIV Enhances Acquisition of Heterologous SIVsmE660 in Acutely Vaccinated Rhesus Macaques

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE; CHEMOKINE RECEPTOR; CHEMOKINE RECEPTOR CCR5; LIVE VACCINE; NEF PROTEIN; REV PROTEIN; VIRUS VACCINE;

EID: 84884746235     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0075556     Document Type: Article
Times cited : (8)

References (66)
  • 1
    • 77955517683 scopus 로고    scopus 로고
    • HIV vaccines: lessons learned and the way forward
    • doi:10.1097/COH.0b013e32833d17ac
    • Kim JH, Rerks-Ngarm S, Excler JL, Michael NL, (2010) HIV vaccines: lessons learned and the way forward. Curr Opin HIV Aids 5: 428-434. doi:10.1097/COH.0b013e32833d17ac. PubMed: 20978385.
    • (2010) Curr Opin HIV Aids , vol.5 , pp. 428-434
    • Kim, J.H.1    Rerks-Ngarm, S.2    Excler, J.L.3    Michael, N.L.4
  • 2
    • 0027043276 scopus 로고
    • Protective effects of a live attenuated SIV vaccine with a deletion in the nef gene
    • doi:10.1126/science.1470917
    • Daniel MD, Kirchhoff F, Czajak SC, Sehgal PK, Desrosiers RC, (1992) Protective effects of a live attenuated SIV vaccine with a deletion in the nef gene. Science 258: 1938-1941. doi:10.1126/science.1470917. PubMed: 1470917.
    • (1992) Science , vol.258 , pp. 1938-1941
    • Daniel, M.D.1    Kirchhoff, F.2    Czajak, S.C.3    Sehgal, P.K.4    Desrosiers, R.C.5
  • 3
    • 29244474887 scopus 로고    scopus 로고
    • HIV vaccine design: insights from live attenuated SIV vaccines
    • doi:10.1038/ni1296
    • Koff WC, Johnson PR, Watkins DI, Burton DR, Lifson JD, et al. (2006) HIV vaccine design: insights from live attenuated SIV vaccines. Nat Immunol 7: 19-23. doi:10.1038/ni1296. PubMed: 16357854.
    • (2006) Nat Immunol , vol.7 , pp. 19-23
    • Koff, W.C.1    Johnson, P.R.2    Watkins, D.I.3    Burton, D.R.4    Lifson, J.D.5
  • 4
    • 0032546173 scopus 로고    scopus 로고
    • Ethics of placebo-controlled trials of zidovudine to prevent the perinatal transmission of HIV in the Third World
    • Lallemant M, McIntosh K, Jourdain G, Le Coeur S, Vithayasai V, et al. (1998) Ethics of placebo-controlled trials of zidovudine to prevent the perinatal transmission of HIV in the Third World. N Engl J Med 338: 831-840; author reply 950863895086379508636.
    • (1998) N Engl J Med , vol.338 , pp. 831-840
    • Lallemant, M.1    McIntosh, K.2    Jourdain, G.3    Le Coeur, S.4    Vithayasai, V.5
  • 5
    • 3042819783 scopus 로고    scopus 로고
    • Live attenuated HIV vaccines: pitfalls and prospects
    • doi:10.1097/00001432-200402000-00004
    • Whitney JB, Ruprecht RM, (2004) Live attenuated HIV vaccines: pitfalls and prospects. Curr Opin Infect Dis 17: 17-26. doi:10.1097/00001432-200402000-00004. PubMed: 15090885.
    • (2004) Curr Opin Infect Dis , vol.17 , pp. 17-26
    • Whitney, J.B.1    Ruprecht, R.M.2
  • 6
    • 0029951823 scopus 로고    scopus 로고
    • Vaccine protection by a triple deletion mutant of simian immunodeficiency virus
    • Wyand MS, Manson KH, Garcia-Moll M, Montefiori D, Desrosiers RC, (1996) Vaccine protection by a triple deletion mutant of simian immunodeficiency virus. J Virol 70: 3724-3733. PubMed: 8648707.
    • (1996) J Virol , vol.70 , pp. 3724-3733
    • Wyand, M.S.1    Manson, K.H.2    Garcia-Moll, M.3    Montefiori, D.4    Desrosiers, R.C.5
  • 7
    • 80051538295 scopus 로고    scopus 로고
    • Early potent protection against heterologous SIVsmE660 challenge following live attenuated SIV vaccination in Mauritian cynomolgus macaques
    • doi:10.1371/journal.pone.0023092
    • Berry N, Ham C, Mee ET, Rose NJ, Mattiuzzo G, et al. (2011) Early potent protection against heterologous SIVsmE660 challenge following live attenuated SIV vaccination in Mauritian cynomolgus macaques. PLOS ONE 6: e23092. doi:10.1371/journal.pone.0023092. PubMed: 21853072.
    • (2011) PLOS ONE , vol.6
    • Berry, N.1    Ham, C.2    Mee, E.T.3    Rose, N.J.4    Mattiuzzo, G.5
  • 8
    • 0032481040 scopus 로고    scopus 로고
    • Live attenuated simian immunodeficiency virus (SIV)mac in macaques can induce protection against mucosal infection with SIVsm
    • doi:10.1097/00002030-199817000-00006
    • Nilsson C, Mäkitalo B, Thorstensson R, Norley S, Binninger-Schinzel D, et al. (1998) Live attenuated simian immunodeficiency virus (SIV)mac in macaques can induce protection against mucosal infection with SIVsm. AIDS 12: 2261-2270. doi:10.1097/00002030-199817000-00006. PubMed: 9863867.
    • (1998) AIDS , vol.12 , pp. 2261-2270
    • Nilsson, C.1    Mäkitalo, B.2    Thorstensson, R.3    Norley, S.4    Binninger-Schinzel, D.5
  • 9
    • 77956042087 scopus 로고    scopus 로고
    • Macaques vaccinated with simian immunodeficiency virus SIVmac239Delta nef delay acquisition and control replication after repeated low-dose heterologous SIV challenge
    • doi:10.1128/JVI.00041-10
    • Reynolds MR, Weiler AM, Piaskowski SM, Kolar HL, Hessell AJ, et al. (2010) Macaques vaccinated with simian immunodeficiency virus SIVmac239Delta nef delay acquisition and control replication after repeated low-dose heterologous SIV challenge. J Virol 84: 9190-9199. doi:10.1128/JVI.00041-10. PubMed: 20592091.
    • (2010) J Virol , vol.84 , pp. 9190-9199
    • Reynolds, M.R.1    Weiler, A.M.2    Piaskowski, S.M.3    Kolar, H.L.4    Hessell, A.J.5
  • 10
    • 58149143041 scopus 로고    scopus 로고
    • Macaques vaccinated with live-attenuated SIV control replication of heterologous virus
    • doi:10.1084/jem.20081524
    • Reynolds MR, Weiler AM, Weisgrau KL, Piaskowski SM, Furlott JR, et al. (2008) Macaques vaccinated with live-attenuated SIV control replication of heterologous virus. J Exp Med 205: 2537-2550. doi:10.1084/jem.20081524. PubMed: 18838548.
    • (2008) J Exp Med , vol.205 , pp. 2537-2550
    • Reynolds, M.R.1    Weiler, A.M.2    Weisgrau, K.L.3    Piaskowski, S.M.4    Furlott, J.R.5
  • 11
    • 0032849066 scopus 로고    scopus 로고
    • Protection by live, attenuated simian immunodeficiency virus against heterologous challenge
    • Wyand MS, Manson K, Montefiori DC, Lifson JD, Johnson RP, et al. (1999) Protection by live, attenuated simian immunodeficiency virus against heterologous challenge. J Virol 73: 8356-8363. PubMed: 10482586.
    • (1999) J Virol , vol.73 , pp. 8356-8363
    • Wyand, M.S.1    Manson, K.2    Montefiori, D.C.3    Lifson, J.D.4    Johnson, R.P.5
  • 12
    • 0038618867 scopus 로고    scopus 로고
    • Determinants of increased replicative capacity of serially passaged simian immunodeficiency virus with nef deleted in rhesus monkeys
    • doi:10.1128/JVI.77.12.6823-6835.2003
    • Alexander L, Illyinskii PO, Lang SM, Means RE, Lifson J, et al. (2003) Determinants of increased replicative capacity of serially passaged simian immunodeficiency virus with nef deleted in rhesus monkeys. J Virol 77: 6823-6835. doi:10.1128/JVI.77.12.6823-6835.2003. PubMed: 12768002.
    • (2003) J Virol , vol.77 , pp. 6823-6835
    • Alexander, L.1    Illyinskii, P.O.2    Lang, S.M.3    Means, R.E.4    Lifson, J.5
  • 13
    • 0028944667 scopus 로고
    • Pathogenicity of live, attenuated SIV after mucosal infection of neonatal macaques
    • doi:10.1126/science.7892606
    • Baba TW, Jeong YS, Pennick D, Bronson R, Greene MF, et al. (1995) Pathogenicity of live, attenuated SIV after mucosal infection of neonatal macaques. Science 267: 1820-1825. doi:10.1126/science.7892606. PubMed: 7892606.
    • (1995) Science , vol.267 , pp. 1820-1825
    • Baba, T.W.1    Jeong, Y.S.2    Pennick, D.3    Bronson, R.4    Greene, M.F.5
  • 14
    • 0032905068 scopus 로고    scopus 로고
    • Live attenuated, multiply deleted simian immunodeficiency virus causes AIDS in infant and adult macaques
    • doi:10.1038/5557
    • Baba TW, Liska V, Khimani AH, Ray NB, Dailey PJ, et al. (1999) Live attenuated, multiply deleted simian immunodeficiency virus causes AIDS in infant and adult macaques. Nat Med 5: 194-203. doi:10.1038/5557. PubMed: 9930868.
    • (1999) Nat Med , vol.5 , pp. 194-203
    • Baba, T.W.1    Liska, V.2    Khimani, A.H.3    Ray, N.B.4    Dailey, P.J.5
  • 15
    • 0042062345 scopus 로고    scopus 로고
    • Convergent evolution of SIV env after independent inoculation of rhesus macaques with infectious proviral DNA
    • doi:10.1016/S0042-6822(03)00262-9
    • Buckley KA, Li PL, Khimani AH, Hofmann-Lehmann R, Liska V, et al. (2003) Convergent evolution of SIV env after independent inoculation of rhesus macaques with infectious proviral DNA. Virology 312: 470-480. doi:10.1016/S0042-6822(03)00262-9. PubMed: 12919751.
    • (2003) Virology , vol.312 , pp. 470-480
    • Buckley, K.A.1    Li, P.L.2    Khimani, A.H.3    Hofmann-Lehmann, R.4    Liska, V.5
  • 16
    • 0031929672 scopus 로고    scopus 로고
    • Identification of highly attenuated mutants of simian immunodeficiency virus
    • Desrosiers RC, Lifson JD, Gibbs JS, Czajak SC, Howe AY, et al. (1998) Identification of highly attenuated mutants of simian immunodeficiency virus. J Virol 72: 1431-1437. PubMed: 9445045.
    • (1998) J Virol , vol.72 , pp. 1431-1437
    • Desrosiers, R.C.1    Lifson, J.D.2    Gibbs, J.S.3    Czajak, S.C.4    Howe, A.Y.5
  • 17
    • 0028293115 scopus 로고
    • Construction and in vitro properties of SIVmac mutants with deletions in "nonessential" genes
    • doi:10.1089/aid.1994.10.607
    • Gibbs JS, Regier DA, Desrosiers RC, (1994) Construction and in vitro properties of SIVmac mutants with deletions in "nonessential" genes. AIDS Res Hum Retroviruses 10: 607-616. doi:10.1089/aid.1994.10.607. PubMed: 7917522.
    • (1994) AIDS Res Hum Retroviruses , vol.10 , pp. 607-616
    • Gibbs, J.S.1    Regier, D.A.2    Desrosiers, R.C.3
  • 18
    • 0025743306 scopus 로고
    • Importance of the nef gene for maintenance of high virus loads and for development of AIDS
    • doi:10.1016/0092-8674(91)90097-I
    • Kestler HW 3rd, Ringler DJ, Mori K, Panicali DL, Sehgal PK, et al. (1991) Importance of the nef gene for maintenance of high virus loads and for development of AIDS. Cell 65: 651-662. doi:10.1016/0092-8674(91)90097-I. PubMed: 2032289.
    • (1991) Cell , vol.65 , pp. 651-662
    • Kestler 3rd, H.W.1    Ringler, D.J.2    Mori, K.3    Panicali, D.L.4    Sehgal, P.K.5
  • 19
    • 0030007364 scopus 로고    scopus 로고
    • Attenuated HIV Vaccine: Caveats
    • doi:10.1126/science.271.5257.1790b
    • Ruprecht RM, Baba TW, Liska V, (1996) Attenuated HIV Vaccine: Caveats. Science 271: 1790b-1791b. doi:10.1126/science.271.5257.1790b. PubMed: 17812356.
    • (1996) Science , vol.271
    • Ruprecht, R.M.1    Baba, T.W.2    Liska, V.3
  • 20
    • 0037462706 scopus 로고    scopus 로고
    • Live attenuated, nef-deleted SIV is pathogenic in most adult macaques after prolonged observation
    • doi:10.1097/00002030-200301240-00004
    • Hofmann-Lehmann R, Vlasak J, Williams AL, Chenine AL, McClure HM, et al. (2003) Live attenuated, nef-deleted SIV is pathogenic in most adult macaques after prolonged observation. AIDS 17: 157-166. doi:10.1097/00002030-200301240-00004. PubMed: 12545074.
    • (2003) AIDS , vol.17 , pp. 157-166
    • Hofmann-Lehmann, R.1    Vlasak, J.2    Williams, A.L.3    Chenine, A.L.4    McClure, H.M.5
  • 21
    • 0034854361 scopus 로고    scopus 로고
    • An examination of signs of disease progression in survivors of the Sydney Blood Bank Cohort (SBBC)
    • doi:10.1016/S1386-6532(01)00198-6
    • Birch MR, Learmont JC, Dyer WB, Deacon NJ, Zaunders JJ, et al. (2001) An examination of signs of disease progression in survivors of the Sydney Blood Bank Cohort (SBBC). J Clin Virol 22: 263-270. doi:10.1016/S1386-6532(01)00198-6. PubMed: 11564591.
    • (2001) J Clin Virol , vol.22 , pp. 263-270
    • Birch, M.R.1    Learmont, J.C.2    Dyer, W.B.3    Deacon, N.J.4    Zaunders, J.J.5
  • 22
    • 0033519616 scopus 로고    scopus 로고
    • Immunologic and virologic status after 14 to 18 years of infection with an attenuated strain of HIV-1. A report from the Sydney Blood Bank Cohort
    • doi:10.1056/NEJM199906033402203
    • Learmont JC, Geczy AF, Mills J, Ashton LJ, Raynes-Greenow CH, et al. (1999) Immunologic and virologic status after 14 to 18 years of infection with an attenuated strain of HIV-1. A report from the Sydney Blood Bank Cohort. N Engl J Med 340: 1715-1722. doi:10.1056/NEJM199906033402203. PubMed: 10352163.
    • (1999) N Engl J Med , vol.340 , pp. 1715-1722
    • Learmont, J.C.1    Geczy, A.F.2    Mills, J.3    Ashton, L.J.4    Raynes-Greenow, C.H.5
  • 23
    • 0030845511 scopus 로고    scopus 로고
    • Replacement of posttranscriptional regulation in SIVmac239 generated a Rev-independent infectious virus able to propagate in rhesus peripheral blood mononuclear cells
    • doi:10.1006/viro.1997.8567
    • von Gegerfelt A, Felber BK, (1997) Replacement of posttranscriptional regulation in SIVmac239 generated a Rev-independent infectious virus able to propagate in rhesus peripheral blood mononuclear cells. Virology 232: 291-299. doi:10.1006/viro.1997.8567. PubMed: 9191842.
    • (1997) Virology , vol.232 , pp. 291-299
    • von Gegerfelt, A.1    Felber, B.K.2
  • 24
    • 33144489199 scopus 로고    scopus 로고
    • RTE and CTE mRNA export elements synergistically increase expression of unstable, Rev-dependent HIV and SIV mRNAs
    • Smulevitch S, Bear J, Alicea C, Rosati M, Jalah R, et al. (2006) RTE and CTE mRNA export elements synergistically increase expression of unstable, Rev-dependent HIV and SIV mRNAs. Retrovirology 3: 6.
    • (2006) Retrovirology , vol.3 , pp. 6
    • Smulevitch, S.1    Bear, J.2    Alicea, C.3    Rosati, M.4    Jalah, R.5
  • 25
    • 0036133087 scopus 로고    scopus 로고
    • Rev-independent simian immunodeficiency virus strains are nonpathogenic in neonatal macaques
    • von Gegerfelt AS, Liska V, Li PL, McClure HM, Horie K, et al. 2002) Rev-independent simian immunodeficiency virus strains are nonpathogenic in neonatal macaques. J Virol 76: 96-104.
    • (2002) J Virol , vol.76 , pp. 96-104
    • von Gegerfelt, A.S.1    Liska, V.2    Li, P.L.3    McClure, H.M.4    Horie, K.5
  • 26
    • 0032991726 scopus 로고    scopus 로고
    • Persistent infection of rhesus macaques by the rev-independent Nef(-) simian immunodeficiency virus SIVmac239: replication kinetics and genomic stability
    • von Gegerfelt AS, Liska V, Ray NB, McClure HM, Ruprecht RM, et al. (1999) Persistent infection of rhesus macaques by the rev-independent Nef(-) simian immunodeficiency virus SIVmac239: replication kinetics and genomic stability. J Virol 73: 6159-6165. PubMed: 10364376.
    • (1999) J Virol , vol.73 , pp. 6159-6165
    • von Gegerfelt, A.S.1    Liska, V.2    Ray, N.B.3    McClure, H.M.4    Ruprecht, R.M.5
  • 27
    • 33745684330 scopus 로고    scopus 로고
    • Long lasting control and lack of pathogenicity of the attenuated Rev-independent SIV in rhesus macaques
    • von Gegerfelt AS, Alicea C, Valentin A, Morrow M, van Rompay KK, et al. (2006) Long lasting control and lack of pathogenicity of the attenuated Rev-independent SIV in rhesus macaques. AIDS Res Hum Retroviruses 22: 516-528.
    • (2006) AIDS Res Hum Retroviruses , vol.22 , pp. 516-528
    • von Gegerfelt, A.S.1    Alicea, C.2    Valentin, A.3    Morrow, M.4    van Rompay, K.K.5
  • 28
    • 77955434386 scopus 로고    scopus 로고
    • Protection of macaques with diverse MHC genotypes against a heterologous SIV by vaccination with a deglycosylated live-attenuated SIV
    • doi:10.1371/journal.pone.0011678
    • Sugimoto C, Watanabe S, Naruse T, Kajiwara E, Shiino T, et al. (2010) Protection of macaques with diverse MHC genotypes against a heterologous SIV by vaccination with a deglycosylated live-attenuated SIV. PLOS ONE 5: e11678. doi:10.1371/journal.pone.0011678. PubMed: 20652030.
    • (2010) PLOS ONE , vol.5
    • Sugimoto, C.1    Watanabe, S.2    Naruse, T.3    Kajiwara, E.4    Shiino, T.5
  • 29
    • 20744444986 scopus 로고    scopus 로고
    • Effect of CD8+ lymphocyte depletion on virus containment after simian immunodeficiency virus SIVmac251 challenge of live attenuated SIVmac239delta3-vaccinated rhesus macaques
    • doi:10.1128/JVI.79.13.8131-8141.2005
    • Schmitz JE, Johnson RP, McClure HM, Manson KH, Wyand MS, et al. (2005) Effect of CD8+ lymphocyte depletion on virus containment after simian immunodeficiency virus SIVmac251 challenge of live attenuated SIVmac239delta3-vaccinated rhesus macaques. J Virol 79: 8131-8141. doi:10.1128/JVI.79.13.8131-8141.2005. PubMed: 15956558.
    • (2005) J Virol , vol.79 , pp. 8131-8141
    • Schmitz, J.E.1    Johnson, R.P.2    McClure, H.M.3    Manson, K.H.4    Wyand, M.S.5
  • 30
    • 0031849757 scopus 로고    scopus 로고
    • Temporal analyses of virus replication, immune responses, and efficacy in rhesus macaques immunized with a live, attenuated simian immunodeficiency virus vaccine
    • Connor RI, Montefiori DC, Binley JM, Moore JP, Bonhoeffer S, et al. (1998) Temporal analyses of virus replication, immune responses, and efficacy in rhesus macaques immunized with a live, attenuated simian immunodeficiency virus vaccine. J Virol 72: 7501-7509. PubMed: 9696847.
    • (1998) J Virol , vol.72 , pp. 7501-7509
    • Connor, R.I.1    Montefiori, D.C.2    Binley, J.M.3    Moore, J.P.4    Bonhoeffer, S.5
  • 31
    • 33750590099 scopus 로고    scopus 로고
    • AIDS vaccine development and challenge viruses: getting real
    • doi:10.1097/QAD.0b013e328010beb5
    • Vlasak J, Ruprecht RM, (2006) AIDS vaccine development and challenge viruses: getting real. AIDS 20: 2135-2140. doi:10.1097/QAD.0b013e328010beb5. PubMed: 17086052.
    • (2006) AIDS , vol.20 , pp. 2135-2140
    • Vlasak, J.1    Ruprecht, R.M.2
  • 32
    • 0034284924 scopus 로고    scopus 로고
    • Sensitive and robust one-tube real-time reverse transcriptase-polymerase chain reaction to quantify SIV RNA load: comparison of one- versus two-enzyme systems
    • doi:10.1089/08892220050117014
    • Hofmann-Lehmann R, Swenerton RK, Liska V, Leutenegger CM, Lutz H, et al. (2000) Sensitive and robust one-tube real-time reverse transcriptase-polymerase chain reaction to quantify SIV RNA load: comparison of one- versus two-enzyme systems. AIDS Res Hum Retrovir 16: 1247-1257. doi:10.1089/08892220050117014. PubMed: 10957722.
    • (2000) AIDS Res Hum Retrovir , vol.16 , pp. 1247-1257
    • Hofmann-Lehmann, R.1    Swenerton, R.K.2    Liska, V.3    Leutenegger, C.M.4    Lutz, H.5
  • 33
    • 23844524271 scopus 로고    scopus 로고
    • Highly sensitive SIV plasma viral load assay: practical considerations, realistic performance expectations, and application to reverse engineering of vaccines for AIDS
    • doi:10.1111/j.1600-0684.2005.00128.x
    • Cline AN, Bess JW, Piatak M Jr., Lifson JD, (2005) Highly sensitive SIV plasma viral load assay: practical considerations, realistic performance expectations, and application to reverse engineering of vaccines for AIDS. J Med Primatol 34: 303-312. doi:10.1111/j.1600-0684.2005.00128.x. PubMed: 16128925.
    • (2005) J Med Primatol , vol.34 , pp. 303-312
    • Cline, A.N.1    Bess, J.W.2    Piatak Jr., M.3    Lifson, J.D.4
  • 34
    • 80052488115 scopus 로고    scopus 로고
    • The TRIM5{alpha} genotype of rhesus macaques affects acquisition of simian immunodeficiency virus SIVsmE660 infection after repeated limiting-dose intrarectal challenge
    • doi:10.1128/JVI.05074-11
    • Reynolds MR, Sacha JB, Weiler AM, Borchardt GJ, Glidden CE, et al. (2011) The TRIM5{alpha} genotype of rhesus macaques affects acquisition of simian immunodeficiency virus SIVsmE660 infection after repeated limiting-dose intrarectal challenge. J Virol 85: 9637-9640. doi:10.1128/JVI.05074-11. PubMed: 21734037.
    • (2011) J Virol , vol.85 , pp. 9637-9640
    • Reynolds, M.R.1    Sacha, J.B.2    Weiler, A.M.3    Borchardt, G.J.4    Glidden, C.E.5
  • 35
    • 84874232605 scopus 로고    scopus 로고
    • DNA and virus particle vaccination protects against acquisition and confers control of viremia upon heterologous simian immunodeficiency virus challenge
    • doi:10.1073/pnas.1215393110
    • Patel V, Jalah R, Kulkarni V, Valentin A, Rosati M, et al. (2013) DNA and virus particle vaccination protects against acquisition and confers control of viremia upon heterologous simian immunodeficiency virus challenge. Proc Natl Acad Sci U S A 110: 2975-2980. doi:10.1073/pnas.1215393110. PubMed: 23359688.
    • (2013) Proc Natl Acad Sci U S A , vol.110 , pp. 2975-2980
    • Patel, V.1    Jalah, R.2    Kulkarni, V.3    Valentin, A.4    Rosati, M.5
  • 36
    • 79957947384 scopus 로고    scopus 로고
    • Prevention of infection by a granulocyte-macrophage colony-stimulating factor co-expressing DNA/modified vaccinia Ankara simian immunodeficiency virus vaccine
    • doi:10.1093/infdis/jir071
    • Lai L, Kwa S, Kozlowski PA, Montefiori DC, Ferrari G, et al. (2011) Prevention of infection by a granulocyte-macrophage colony-stimulating factor co-expressing DNA/modified vaccinia Ankara simian immunodeficiency virus vaccine. J Infect Dis 204: 164-173. doi:10.1093/infdis/jir071. PubMed: 21628671.
    • (2011) J Infect Dis , vol.204 , pp. 164-173
    • Lai, L.1    Kwa, S.2    Kozlowski, P.A.3    Montefiori, D.C.4    Ferrari, G.5
  • 37
    • 79955680409 scopus 로고    scopus 로고
    • Immune and Genetic Correlates of Vaccine Protection Against Mucosal Infection by SIV in Monkeys
    • Letvin NL, Rao SS, Montefiori DC, Seaman MS, Sun Y, et al. (2011) Immune and Genetic Correlates of Vaccine Protection Against Mucosal Infection by SIV in Monkeys. Sci Transl Med 3: 81ra36. PubMed: 21543722.
    • (2011) Sci Transl Med , vol.3
    • Letvin, N.L.1    Rao, S.S.2    Montefiori, D.C.3    Seaman, M.S.4    Sun, Y.5
  • 38
    • 77956832938 scopus 로고    scopus 로고
    • TRIM5 suppresses cross-species transmission of a primate immunodeficiency virus and selects for emergence of resistant variants in the new species
    • Kirmaier A, Wu F, Newman RM, Hall LR, Morgan JS, et al. (2010) TRIM5 suppresses cross-species transmission of a primate immunodeficiency virus and selects for emergence of resistant variants in the new species. PLOS Biol 8.
    • (2010) PLOS Biol , vol.8
    • Kirmaier, A.1    Wu, F.2    Newman, R.M.3    Hall, L.R.4    Morgan, J.S.5
  • 39
    • 77649201236 scopus 로고    scopus 로고
    • TRIM5alpha Modulates Immunodeficiency Virus Control in Rhesus Monkeys
    • Lim SY, Rogers T, Chan T, Whitney JB, Kim J, et al. (2010) TRIM5alpha Modulates Immunodeficiency Virus Control in Rhesus Monkeys. PLOS Pathog 6: e1000738. PubMed: 20107597.
    • (2010) PLOS Pathog , vol.6
    • Lim, S.Y.1    Rogers, T.2    Chan, T.3    Whitney, J.B.4    Kim, J.5
  • 40
    • 0029652922 scopus 로고
    • Protection by attenuated simian immunodeficiency virus in macaques against challenge with virus-infected cells
    • doi:10.1016/S0140-6736(95)92540-6
    • Almond N, Kent K, Cranage M, Rud E, Clarke B, et al. (1995) Protection by attenuated simian immunodeficiency virus in macaques against challenge with virus-infected cells. Lancet 345: 1342-1344. doi:10.1016/S0140-6736(95)92540-6. PubMed: 7752758.
    • (1995) Lancet , vol.345 , pp. 1342-1344
    • Almond, N.1    Kent, K.2    Cranage, M.3    Rud, E.4    Clarke, B.5
  • 41
    • 0032996128 scopus 로고    scopus 로고
    • Highly attenuated vaccine strains of simian immunodeficiency virus protect against vaginal challenge: inverse relationship of degree of protection with level of attenuation
    • Johnson RP, Lifson JD, Czajak SC, Cole KS, Manson KH, et al. (1999) Highly attenuated vaccine strains of simian immunodeficiency virus protect against vaginal challenge: inverse relationship of degree of protection with level of attenuation. J Virol 73: 4952-4961. PubMed: 10233957.
    • (1999) J Virol , vol.73 , pp. 4952-4961
    • Johnson, R.P.1    Lifson, J.D.2    Czajak, S.C.3    Cole, K.S.4    Manson, K.H.5
  • 42
    • 0030806029 scopus 로고    scopus 로고
    • Induction of vigorous cytotoxic T-lymphocyte responses by live attenuated simian immunodeficiency virus
    • Johnson RP, Glickman RL, Yang JQ, Kaur A, Dion JT, et al. (1997) Induction of vigorous cytotoxic T-lymphocyte responses by live attenuated simian immunodeficiency virus. J Virol 71: 7711-7718. PubMed: 9311855.
    • (1997) J Virol , vol.71 , pp. 7711-7718
    • Johnson, R.P.1    Glickman, R.L.2    Yang, J.Q.3    Kaur, A.4    Dion, J.T.5
  • 43
    • 0037007670 scopus 로고    scopus 로고
    • HIV preferentially infects HIV-specific CD4+ T cells
    • doi:10.1038/417095a
    • Douek DC, Brenchley JM, Betts MR, Ambrozak DR, Hill BJ, et al. (2002) HIV preferentially infects HIV-specific CD4+ T cells. Nature 417: 95-98. doi:10.1038/417095a. PubMed: 11986671.
    • (2002) Nature , vol.417 , pp. 95-98
    • Douek, D.C.1    Brenchley, J.M.2    Betts, M.R.3    Ambrozak, D.R.4    Hill, B.J.5
  • 44
    • 0034608653 scopus 로고    scopus 로고
    • Effects of in vivo CD8(+) T cell depletion on virus replication in rhesus macaques immunized with a live, attenuated simian immunodeficiency virus vaccine
    • doi:10.1084/jem.191.11.1921
    • Metzner KJ, Jin X, Lee FV, Gettie A, Bauer DE, et al. (2000) Effects of in vivo CD8(+) T cell depletion on virus replication in rhesus macaques immunized with a live, attenuated simian immunodeficiency virus vaccine. J Exp Med 191: 1921-1931. doi:10.1084/jem.191.11.1921. PubMed: 10839807.
    • (2000) J Exp Med , vol.191 , pp. 1921-1931
    • Metzner, K.J.1    Jin, X.2    Lee, F.V.3    Gettie, A.4    Bauer, D.E.5
  • 45
    • 80052288358 scopus 로고    scopus 로고
    • Comparison of immune responses generated by optimized DNA vaccination against SIV antigens in mice and macaques
    • doi:10.1016/j.vaccine.2010.12.056
    • Kulkarni V, Jalah R, Ganneru B, Bergamaschi C, Alicea C, et al. (2011) Comparison of immune responses generated by optimized DNA vaccination against SIV antigens in mice and macaques. Vaccine 29: 6742-6754. doi:10.1016/j.vaccine.2010.12.056. PubMed: 21195080.
    • (2011) Vaccine , vol.29 , pp. 6742-6754
    • Kulkarni, V.1    Jalah, R.2    Ganneru, B.3    Bergamaschi, C.4    Alicea, C.5
  • 46
    • 84869198702 scopus 로고    scopus 로고
    • Lymph node T cell responses predict the efficacy of live attenuated SIV vaccines
    • doi:10.1038/nm.2934
    • Fukazawa Y, Park H, Cameron MJ, Lefebvre F, Lum R, et al. (2012) Lymph node T cell responses predict the efficacy of live attenuated SIV vaccines. Nat Med 18: 1673-1681. doi:10.1038/nm.2934. PubMed: 22961108.
    • (2012) Nat Med , vol.18 , pp. 1673-1681
    • Fukazawa, Y.1    Park, H.2    Cameron, M.J.3    Lefebvre, F.4    Lum, R.5
  • 47
    • 65449179917 scopus 로고    scopus 로고
    • Contribution of nonneutralizing vaccine-elicited antibody activities to improved protective efficacy in rhesus macaques immunized with Tat/Env compared with multigenic vaccines
    • doi:10.4049/jimmunol.0803115
    • Florese RH, Demberg T, Xiao P, Kuller L, Larsen K, et al. (2009) Contribution of nonneutralizing vaccine-elicited antibody activities to improved protective efficacy in rhesus macaques immunized with Tat/Env compared with multigenic vaccines. J Immunol 182: 3718-3727. doi:10.4049/jimmunol.0803115. PubMed: 19265150.
    • (2009) J Immunol , vol.182 , pp. 3718-3727
    • Florese, R.H.1    Demberg, T.2    Xiao, P.3    Kuller, L.4    Larsen, K.5
  • 48
    • 69549103041 scopus 로고    scopus 로고
    • Fc receptor-mediated antiviral antibodies
    • doi:10.1097/COH.0b013e32832f0a89
    • Forthal DN, Moog C, (2009) Fc receptor-mediated antiviral antibodies. Curr Opin HIV Aids 4: 388-393. doi:10.1097/COH.0b013e32832f0a89. PubMed: 20048702.
    • (2009) Curr Opin HIV Aids , vol.4 , pp. 388-393
    • Forthal, D.N.1    Moog, C.2
  • 49
    • 85027927845 scopus 로고    scopus 로고
    • Impact of herpes simplex virus type 2 on HIV-1 acquisition and progression in an HIV vaccine trial (the Step study)
    • doi:10.1097/QAI.0b013e31821acb5
    • Barnabas RV, Wasserheit JN, Huang Y, Janes H, Morrow R, et al. (2011) Impact of herpes simplex virus type 2 on HIV-1 acquisition and progression in an HIV vaccine trial (the Step study). J Acquir Immune Defic Syndr 57: 238-244. doi:10.1097/QAI.0b013e31821acb5. PubMed: 21860356.
    • (2011) J Acquir Immune Defic Syndr , vol.57 , pp. 238-244
    • Barnabas, R.V.1    Wasserheit, J.N.2    Huang, Y.3    Janes, H.4    Morrow, R.5
  • 50
    • 77951237291 scopus 로고    scopus 로고
    • A macaque model to study vaginal HSV-2/immunodeficiency virus co-infection and the impact of HSV-2 on microbicide efficacy
    • doi:10.1371/journal.pone.0008060
    • Crostarosa F, Aravantinou M, Akpogheneta OJ, Jasny E, Shaw A, et al. (2009) A macaque model to study vaginal HSV-2/immunodeficiency virus co-infection and the impact of HSV-2 on microbicide efficacy. PLOS ONE 4: e8060. doi:10.1371/journal.pone.0008060. PubMed: 20011586.
    • (2009) PLOS ONE , vol.4
    • Crostarosa, F.1    Aravantinou, M.2    Akpogheneta, O.J.3    Jasny, E.4    Shaw, A.5
  • 51
    • 29144444035 scopus 로고    scopus 로고
    • Herpes simplex virus 2 infection increases HIV acquisition in men and women: systematic review and meta-analysis of longitudinal studies
    • doi:10.1097/01.aids.0000198081.09337.a7
    • Freeman EE, Weiss HA, Glynn JR, Cross PL, Whitworth JA, et al. (2006) Herpes simplex virus 2 infection increases HIV acquisition in men and women: systematic review and meta-analysis of longitudinal studies. AIDS 20: 73-83. doi:10.1097/01.aids.0000198081.09337.a7. PubMed: 16327322.
    • (2006) AIDS , vol.20 , pp. 73-83
    • Freeman, E.E.1    Weiss, H.A.2    Glynn, J.R.3    Cross, P.L.4    Whitworth, J.A.5
  • 52
    • 65549104201 scopus 로고    scopus 로고
    • Effect of HSV-2 serostatus on acquisition of HIV by young men: results of a longitudinal study in Orange Farm, South Africa
    • doi:10.1086/597208
    • Sobngwi-Tambekou J, Taljaard D, Lissouba P, Zarca K, Puren A, et al. (2009) Effect of HSV-2 serostatus on acquisition of HIV by young men: results of a longitudinal study in Orange Farm, South Africa. J Infect Dis 199: 958-964. doi:10.1086/597208. PubMed: 19220143.
    • (2009) J Infect Dis , vol.199 , pp. 958-964
    • Sobngwi-Tambekou, J.1    Taljaard, D.2    Lissouba, P.3    Zarca, K.4    Puren, A.5
  • 53
    • 56149127456 scopus 로고    scopus 로고
    • Acute Schistosoma mansoni infection increases susceptibility to systemic SHIV clade C infection in rhesus macaques after mucosal virus exposure
    • Chenine AL, Shai-Kobiler E, Steele LN, Ong H, Augostini P, et al. (2008) Acute Schistosoma mansoni infection increases susceptibility to systemic SHIV clade C infection in rhesus macaques after mucosal virus exposure. PLoS Negl Trop. Drosophila Inf Serv 2: e265.
    • (2008) PLoS Negl Trop Drosophila Inf Serv , vol.2
    • Chenine, A.L.1    Shai-Kobiler, E.2    Steele, L.N.3    Ong, H.4    Augostini, P.5
  • 55
    • 56649105122 scopus 로고    scopus 로고
    • Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): a double-blind, randomised, placebo-controlled, test-of-concept trial
    • doi:10.1016/S0140-6736(08)61591-3
    • Buchbinder SP, Mehrotra DV, Duerr A, Fitzgerald DW, Mogg R, et al. (2008) Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): a double-blind, randomised, placebo-controlled, test-of-concept trial. Lancet 372: 1881-1893. doi:10.1016/S0140-6736(08)61591-3. PubMed: 19012954.
    • (2008) Lancet , vol.372 , pp. 1881-1893
    • Buchbinder, S.P.1    Mehrotra, D.V.2    Duerr, A.3    Fitzgerald, D.W.4    Mogg, R.5
  • 56
    • 85027927845 scopus 로고    scopus 로고
    • Impact of Herpes Simplex Virus Type 2 on HIV-1 acquisition and progression in an HIV vaccine trial (the Step Study)
    • Barnabas RV, Wasserheit JN, Huang Y, Janes H, Morrow R, et al. (2011) Impact of Herpes Simplex Virus Type 2 on HIV-1 acquisition and progression in an HIV vaccine trial (the Step Study). J Acquir Immune Defic Syndr.
    • (2011) J Acquir Immune Defic Syndr
    • Barnabas, R.V.1    Wasserheit, J.N.2    Huang, Y.3    Janes, H.4    Morrow, R.5
  • 57
    • 56649114351 scopus 로고    scopus 로고
    • HIV-1 vaccine-induced immunity in the test-of-concept Step Study: a case-cohort analysis
    • doi:10.1016/S0140-6736(08)61592-5
    • McElrath MJ, De Rosa SC, Moodie Z, Dubey S, Kierstead L, et al. (2008) HIV-1 vaccine-induced immunity in the test-of-concept Step Study: a case-cohort analysis. Lancet 372: 1894-1905. doi:10.1016/S0140-6736(08)61592-5. PubMed: 19012957.
    • (2008) Lancet , vol.372 , pp. 1894-1905
    • McElrath, M.J.1    De Rosa, S.C.2    Moodie, Z.3    Dubey, S.4    Kierstead, L.5
  • 58
    • 0031943418 scopus 로고    scopus 로고
    • Development and applications of enhanced green fluorescent protein mutants
    • Stauber RH, Horie K, Carney P, Hudson EA, Tarasova NI, et al. (1998) Development and applications of enhanced green fluorescent protein mutants. BioTechniques 24: 462-471. 9526659.
    • (1998) BioTechniques , vol.24 , pp. 462-471
    • Stauber, R.H.1    Horie, K.2    Carney, P.3    Hudson, E.A.4    Tarasova, N.I.5
  • 59
    • 79960561410 scopus 로고    scopus 로고
    • Vaccination against heterologous R5 clade C SHIV: prevention of infection and correlates of protection
    • doi:10.1371/journal.pone.0022010
    • Lakhashe SK, Wang W, Siddappa NB, Hemashettar G, Polacino P, et al. (2011) Vaccination against heterologous R5 clade C SHIV: prevention of infection and correlates of protection. PLOS ONE 6: e22010. doi:10.1371/journal.pone.0022010. PubMed: 21799765.
    • (2011) PLOS ONE , vol.6
    • Lakhashe, S.K.1    Wang, W.2    Siddappa, N.B.3    Hemashettar, G.4    Polacino, P.5
  • 60
    • 0037105530 scopus 로고    scopus 로고
    • MHC class I alleles influence set-point viral load and survival time in simian immunodeficiency virus-infected rhesus monkeys
    • Mühl T, Krawczak M, Ten Haaft P, Hunsmann G, Sauermann U, (2002) MHC class I alleles influence set-point viral load and survival time in simian immunodeficiency virus-infected rhesus monkeys. J Immunol 169: 3438-3446. PubMed: 12218167.
    • (2002) J Immunol , vol.169 , pp. 3438-3446
    • Mühl, T.1    Krawczak, M.2    Ten Haaft, P.3    Hunsmann, G.4    Sauermann, U.5
  • 61
    • 38549142426 scopus 로고    scopus 로고
    • Mhc class I haplotypes associated with survival time in simian immunodeficiency virus (SIV)-infected rhesus macaques
    • doi:10.1038/sj.gene.6364448
    • Sauermann U, Siddiqui R, Suh YS, Platzer M, Leuchte N, et al. (2008) Mhc class I haplotypes associated with survival time in simian immunodeficiency virus (SIV)-infected rhesus macaques. Genes Immun 9: 69-80. doi:10.1038/sj.gene.6364448. PubMed: 18094710.
    • (2008) Genes Immun , vol.9 , pp. 69-80
    • Sauermann, U.1    Siddiqui, R.2    Suh, Y.S.3    Platzer, M.4    Leuchte, N.5
  • 62
    • 12744261504 scopus 로고    scopus 로고
    • Network structures and algorithms in Bioconductor
    • doi:10.1093/bioinformatics/bth458
    • Carey VJ, Gentry J, Whalen E, Gentleman R, (2005) Network structures and algorithms in Bioconductor. Bioinformatics 21: 135-136. doi:10.1093/bioinformatics/bth458. PubMed: 15297301.
    • (2005) Bioinformatics , vol.21 , pp. 135-136
    • Carey, V.J.1    Gentry, J.2    Whalen, E.3    Gentleman, R.4
  • 63
  • 64
    • 28744458859 scopus 로고    scopus 로고
    • Bioconductor: open software development for computational biology and bioinformatics
    • doi:10.1186/gb-2004-5-10-r80
    • Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, et al. (2004) Bioconductor: open software development for computational biology and bioinformatics. Genome Biol 5: R80. doi:10.1186/gb-2004-5-10-r80. PubMed: 15461798.
    • (2004) Genome Biol , vol.5
    • Gentleman, R.C.1    Carey, V.J.2    Bates, D.M.3    Bolstad, B.4    Dettling, M.5
  • 65
    • 79960231294 scopus 로고    scopus 로고
    • cn.FARMS: a latent variable model to detect copy number variations in microarray data with a low false discovery rate
    • Clevert DA, Mitterecker A, Mayr A, Klambauer G, Tuefferd M, et al. (2011) cn.FARMS: a latent variable model to detect copy number variations in microarray data with a low false discovery rate. Nucleic Acids Res, 39: e79-. PubMed: 21486749.
    • (2011) Nucleic Acids Res , vol.39
    • Clevert, D.A.1    Mitterecker, A.2    Mayr, A.3    Klambauer, G.4    Tuefferd, M.5
  • 66
    • 0037311919 scopus 로고    scopus 로고
    • TM4: a free, open-source system for microarray data management and analysis
    • Saeed AI, Sharov V, White J, Li J, Liang W, et al. (2003) TM4: a free, open-source system for microarray data management and analysis. BioTechniques 34: 374-378. PubMed: 12613259.
    • (2003) BioTechniques , vol.34 , pp. 374-378
    • Saeed, A.I.1    Sharov, V.2    White, J.3    Li, J.4    Liang, W.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.