MHC class I alleles influence set-point viral load and survival time in Simian immunodeficiency virus-infected rhesus monkeys

Journal of Immunology

Volumn 169, Issue 6, 2002, Pages 3438-3446

  Mühl, Thorsten ^a   Krawczak, Michael ^a   Ten Haaft, Peter ^a   Hunsmann, Gerhard ^a   Sauermann, Ulrike ^a  

^a GERMAN PRIMATE CENTER   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; VIRUS RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DNA POLYMORPHISM; DNA SEQUENCE; GENE FREQUENCY; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MAJOR HISTOCOMPATIBILITY COMPLEX; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RHESUS MONKEY; SIMIAN IMMUNODEFICIENCY VIRUS; SURVIVAL TIME; VIRUS CELL INTERACTION; VIRUS LOAD;

EID: 0037105530     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.169.6.3438     Document Type: Article

References (46)

1. Variability of viral load in plasma of rhesus monkeys inoculated with simian immunodeficiency virus or simian-human immunodeficiency virus: Implications for using nonhuman primate AIDS models to test vaccines and therapeutics
2. Birth of MHC-defined rhesus monkeys produced by assisted reproductive technology
3. New class I and II HLA alleles strongly associated with opposite patterns of progression to AIDS
4. Combined genotypes of CCR5, CCR2, SDF1, and HLA genes can predict the long-term nonprogressor status in human immunodeficiency virus-1-infected individuals
5. Molecular and functional analysis of a conserved CTL epitope in HIV-1 p24 recognized from a long-term nonprogressor: Constraints on immune escape associated with targeting a sequence essential for viral replication
6. Consistent associations of HLA class I and II and transporter gene products with progression of human immunodeficiency virus type 1 infection in homosexual men
7. Frequency of HLA allele-specific peptide motifs in HIV-1 proteins correlates with the allele's association with relative rates of disease progression after HIV-1 infection
8. HLA-B*5703 independently associated with slower HIV-1 disease progression in Rwandan women
9. HLA b*5701 is highly associated with restriction of virus replication in a subgroup of HIV-infected long term nonprogressors
10. Effect of a single amino acid change in MHC class I molecules on the rate of progression to AIDS
11. Polymorphisms in HLA class I genes associated with both favorable prognosis of human immunodeficiency virus (HIV) type 1 infection and positive cytotoxic T-lymphocyte responses to ALVAC-HIV recombinant canarypox vaccines
12. Distinctive effects of CCR5, CCR2, and SDF1 genetic polymorphisms in AIDS progression
13. Contrasting genetic influence of CCR2 and CCR5 variants on HIV-1 infection and disease progression: Hemophilia Growth and Development Study (HGDS)
14. Major histocompatibility complex genotype is associated with disease progression and virus load levels in a cohort of human immunodeficiency virus type 1-infected Caucasians and African Americans
15. HLA and HIV-1: Heterozygote advantage and B*35-Cw*04 disadvantage
16. HLA class I homozygosity accelerates disease progression in human immunodeficiency virus type 1 infection
17. Correlation of major histocompatibility complex with opportunistic infections in simian immunodeficiency virus-infected rhesus monkeys
18. Rapid and slow progressors differ by a single MHC class I haplotype in a family of MHC-defined rhesus macaques infected with SIV
19. Homozygosity for a conserved Mhc class II DQ-DRB haplotype is associated with rapid disease progression in simian immunodeficiency virus-infected macaques: Results from a prospective study
20. A high frequency of Mamu-A*01 in the rhesus macaque detected by polymerase chain reaction with sequence-specific primers and direct sequencing
21. A common rhesus macaque MHC class I molecule which binds a cytotoxic T-lymphocyte epitope in Nef of simian immunodeficiency virus
22. A commonly recognized simian immunodeficiency virus Nef epitope presented to cytotoxic T lymphocytes of Indian-origin rhesus monkeys by the prevalent major histocompatibitity complex class I allele Mamu-A*02
23. The MHC class I genes of the rhesus monkey: Different evolutionary histories of MHC class I and II genes in primates
24. A high incidence of Shigella-induced arthritis in a primate species: Major histocompatibility complex class I molecules associated with resistance and susceptibility, and their relationship to HLA-B27
25. Mamu-I: A novel primate MHC class I B-related locus with unusually low variability
26. Class I MHC expression in the yellow baboon
27. Species-specific evolution of MHC class I genes in the higher primates
28. Immunization with Tween-ether-treated SIV adsorbed onto aluminum hydroxide protects monkeys against experimental SIV infection
29. Immunization with virion-derived glycoprotein 130 from HIV-2 or SIV protects macaques against challenge virus grown in human or simian cells or prepared ex vivo
30. Simian immunodeficiency virus (SIV) gp130 oligomers protect rhesus macaques (Macaca mulatta) against the infection with SIVmac32H grown on T-cells or derived ex vivo
31. Suppression of viral replication in a long-term nonprogressing rhesus macaque experimentally infected with pathogenic simian immunodeficiency virus (SIV)
32. Identification of Mhc-Mamu-DQB1 allele combinations associated with rapid disease progression in rhesus macaques infected with simian immunodeficiency virus
33. Isolation of T-cell tropic HTLV-III-Iike retrovirus from macaques
34. Protection of monkeys by a split vaccine against SIVmac depends upon biological properties of the challenge virus
35. SIV infection of rhesus macaques: In vivo titration of infectivity and development of an experimental vaccine
36. Immunization with virus-derived gpl30 micelles protects rhesus monkeys against challenge with SIVmac/32H grown either on human T cells or prepared directly from the spleen of an SIV-infected rhesus monkey
37. Characterization of infectious molecular clones of simian immunodeficiency virus (SIVmac) and human immunodeficiency virus type 2: Persistent infection of rhesus monkeys with molecularly cloned SIVmac
38. The complete nucleotide sequence of a pathogenic molecular clone of simian immunodeficiency virus
39. Impaired mitogen-driven proliferation and cytokine transcription of lymphocytes from macaques early after simian immunodeficiency virus (SIV) infection
40. The human immunodeficiency virus type 1 nef gene can to a large extent replace simian immunodeficiency virus nef in vivo
41. A pathogenic threshold of virus load defined in simian immunodeficiency v
42. Definition of five new simian immunodeficiency virus cytotoxic T-lymphocyte epitopes and their restricting major histocompatibility complex class I molecules: Evidence for an influence on disease progression
43. Definition of the Mamu A*01 peptide binding specificity: Application to the identification of wild-type and optimized ligands from simian immunodeficiency virus regulatory proteins
44. Dominance of CD8 responses specific for epitopes bound by a single major histocompatibility complex class I molecule during the acute phase of viral infection
45. ALVACSIV-gag-pol-env-based vaccination and macaque major histocompatibility complex class I (A*01) delay simian immunodeficiency virus SIVmac-induced immunodeficiency
46. Definition of human immunodeficiency virus type 1 gp120 and gp41 cytotoxic T-lymphocyte epitopes and their restricting major histocompatibility complex class I alleles in simian-human immunodeficiency virus-infected rhesus monkeys