Knockdown of AHR1A but not AHR1B exacerbates PAH and PCB-126 toxicity in zebrafish (Danio rerio) embryos

Aquatic Toxicology

Volumn 142-143, Issue , 2013, Pages 336-346

  Garner, Lindsey V T ^a   Brown, Daniel R ^a   Di Giulio, Richard T ^a  

^a DUKE UNIVERSITY   (United States)

Author keywords

Aryl hydrocarbon receptor; Cardiotoxicity; Morpholino; PCB 126; Polycyclic aromatic hydrocarbon; Zebrafish

Indexed keywords

3,3',4,4',5 PENTACHLOROBIPHENYL; AROMATIC HYDROCARBON RECEPTOR; ARYL HYDROCARBON RECEPTOR 1A; ARYL HYDROCARBON RECEPTOR 1B; CYTOCHROME P450; CYTOCHROME P450 1A; CYTOCHROME P450 1B1; CYTOCHROME P450 1C1; MESSENGER RNA; POLYCYCLIC AROMATIC HYDROCARBON; UNCLASSIFIED DRUG;

CYPRINID; EMBRYO; ENVIRONMENTAL CONDITIONS; ENZYME ACTIVITY; GENE; PAH; PCB; PHYSIOLOGICAL RESPONSE; TELEOST; TOXICITY;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARDIOTOXICITY; CONGENITAL HEART MALFORMATION; CONTROLLED STUDY; DISEASE EXACERBATION; ECOTOXICITY; EMBRYO; EMBRYOTOXICITY; ENZYME ACTIVITY; GENE; GENE EXPRESSION; GENE SILENCING; MORPHOLINO GENE; NONHUMAN; PRIORITY JOURNAL; ZEBRA FISH;

ARYL HYDROCARBON RECEPTOR; CARDIOTOXICITY; MORPHOLINO; PCB-126; POLYCYCLIC AROMATIC HYDROCARBON; ZEBRAFISH;

ANIMALS; CYTOCHROME P-450 ENZYME SYSTEM; EMBRYO, NONMAMMALIAN; ENZYME ACTIVATION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE KNOCKDOWN TECHNIQUES; POLYCHLORINATED BIPHENYLS; POLYCYCLIC HYDROCARBONS, AROMATIC; PROTEIN ISOFORMS; RECEPTORS, ARYL HYDROCARBON; WATER POLLUTANTS, CHEMICAL; ZEBRAFISH; ZEBRAFISH PROTEINS;

EID: 84884715533     PISSN: 0166445X     EISSN: 18791514     Source Type: Journal    
DOI: 10.1016/j.aquatox.2013.09.007     Document Type: Article

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