Modulation of chicken intestinal immune gene expression by small cationic peptides as feed additives during the first week posthatch

Clinical and Vaccine Immunology

Volumn 20, Issue 9, 2013, Pages 1440-1448

  Kogut, Michael H ^a   Genovese, Kenneth J ^a   He, Haiqi ^a   Swaggerty, Christina L ^a   Jiang, Yiwei ^b  

^a SOUTHERN PLAINS AGRICULTURAL RESEARCH CENTER   (United States)

^b My Galaxy LLC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMICROBIAL CATIONIC PEPTIDE; BACTERIAL PROTEIN; CHEMOKINE; CXCLI1 CHEMOKINE; CXCLI2 CHEMOKINE; GAMMA INTERFERON; INTERFERON; INTERLEUKIN 15; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 6; MESSENGER RNA; SALMONELLA ENTERITIDIS PATHOGEN ASSOCIATED MOLECULAR PATTERN PROTEIN; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 15; TOLL LIKE RECEPTOR 21; TOLL LIKE RECEPTOR 4; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL FOOD; ANIMAL SALMONELLOSIS; ANIMAL TISSUE; ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIAL COLONIZATION; BROILER; CECUM; CONCENTRATION RESPONSE; CONTROLLED STUDY; CROSS PRESENTATION; DEVELOPMENTAL STAGE; DIET SUPPLEMENTATION; GASTROENTERITIS; GENE EXPRESSION REGULATION; GENE TARGETING; HOST RESISTANCE; IMMUNE RESPONSE; IMMUNOMODULATION; INNATE IMMUNITY; NEWBORN; NONHUMAN; NUCLEOTIDE SEQUENCE; POSTHATCH; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SALMONELLA ENTERITIDIS; TRANSCRIPTION REGULATION; UPREGULATION;

ANIMAL FEED; ANIMALS; BACTERIAL PROTEINS; BREVIBACILLUS; CECUM; CHICKENS; CYTOKINES; DIET; DISEASE MODELS, ANIMAL; FOOD ADDITIVES; GENE EXPRESSION; GENE EXPRESSION PROFILING; IMMUNOLOGIC FACTORS; REAL-TIME POLYMERASE CHAIN REACTION; SALMONELLA ENTERITIDIS; SALMONELLA INFECTIONS, ANIMAL; TOLL-LIKE RECEPTORS;

EID: 84884685246     PISSN: 15566811     EISSN: 1556679X     Source Type: Journal    
DOI: 10.1128/CVI.00322-13     Document Type: Article

References (48)

1. Kogut MH. 2002. Dynamics of a protective avian inflammatory response: the role of an IL-8-like cytokine in the recruitment of heterophils to the site of organ invasion by Salmonella enteritidis. Comp. Immunol. Microbiol. Infect. Dis. 25:159-172.
2. Lowry VK, Farnell MB, Ferro PJ, Swaggerty CL, Bahl A, Kogut MH. 2005. Purified β-glucan as an abiotic feed additive upregulates the innate immune response in immature chickens against Salmonella enterica serovar Enteritidis. Int. J. Food Microbiol. 98:309-318.
3. He H, Lowry VK, Swaggerty CL, Ferro P, Kogut MH. 2005. In vitro activation of chicken leukocytes and in vivo protection against Salmonella enteritidis organ invasion and peritoneal S. enteritidis infection-induced mortality in neonatal chickens by immunomodulatory CpG oligodeoxynucleotide. FEMS Immunol. Med. Microbiol. 43:81-89.
4. Kogut MH, Genovese KJ, He H, Li MA, Jiang YW. 2007. The effects of the BT/TAMUs 2032 cationic peptides on innate immunity and susceptibility of young chickens to extraintestinal Salmonella enterica serovar Enteritidis infection. Int. Immunopharmacol. 7:912-919.
5. Swaggerty CL, Pevzner IY, He H, Genovese KJ, Nisbet DJ, Kaiser P, Kogut MH. 2009. Selection of broilers with improved innate immune responsiveness to reduce on-farm infection by food-borne pathogens: a review. Foodborne Path. Dis. 6:772-783.
6. Wells LL, Lowry VK, DeLoach JR, Kogut MH. 1998. Age dependent phagocytosis and bactericidal activities of the chicken heterophil. Dev. Comp. Immunol. 22:103-109.
7. Wu X, Ballard J, Jiang YW. 2005. Structure and biosynthesis of the BT peptide antibiotic from Brevibacillus texasporus. Appl. Environ. Microbiol. 71:8519-8530.
8. Jiang YW, Sims MD, Conway DP. 2005. The efficacy of TAMUS 2032 in preventing a natural outbreak of colibacillosis in broiler chickens in floor pens. Poult. Sci. 84:1857-1859.
9. Kogut MH, He H, Genovese KJ, Jiang Y. 2010. Feeding the BT cationic peptides to chickens at hatch reduces cecal colonization by Salmonella enterica serovar Enteritidis and primes innate immune cell functional activity. Foodborne Path. Dis. 7:23-30.
10. National Research Council. 1994. Nutritional requirements of poultry, 9th edition. National Academy Press, Washington, DC.
11. Kaiser P, Rothwell L, Galyov EE, Barrow PA, Burnside J, Wigley P. 2000. Differential cytokine expression in avian cells in response to invasion by Salmonella typhimurium, Salmonella enteritidis and Salmonella gallinarum. Microbiology 146(Part 12):3217-3226.
12. Kogut MH, Rothwell L, Kaiser P. 2003. Differential regulation of cytokine gene expression by avian heterophils during receptor-mediated phagocytosis of opsonized and nonopsonized Salmonella enteritidis. J. Interferon Cytokine Res. 23:319-327.
13. Crippen TL, Bischoff KM, Lowry VK, Kogut MH. 2003. P33 activates antimicrobial functions of heterophils from chicken peripheral blood. J. Food Prot. 66:787-792.
14. He H, Genovese KJ, Swaggerty CJ, Nisbet DJ, Kogut MH. 2007. In vivo priming heterophil innate immune functions and increasing resistance to Salmonella enteritidis infection in neonatal chickens by immune stimulatory CpG oligodeoxynucleotides. Vet. Immunol. Immunopathol. 117: 275-283.
15. Genovese KG, He H, Lowry VK, Nisbet DJ, Kogut MH. 2007. Dynamics of the avian inflammatory response to Salmonella following administration of the Toll-like receptor 5 agonist, flagellin. FEMS Immunol. Med. Microbiol. 51:112-117.
16. MacKinnon KM, He H, Swaggerty CL, McReynolds JL, Genovese KJ, Duke SE, Nerren JR, Kogut MH. 2009. In ovo treatment with CpG oligodeoxynucleotides decreases colonization of Salmonella enteriditis in broiler chickens. Vet. Immunol. Immunopathol. 127:371-375.
17. Swaggerty CL, He H, Genovese KJ, Duke SE, Kogut MH. 2012. Loxoribine pretreatment reduces Salmonella Enteritidis organ invasion in 1-day-old chickens. Poult. Sci. 91:1038-1042.
18. McGruder ED, Kogut MH, Corrier DE, DeLoach JR, Hargis BM. 1995. Comparison of prophylactic and therapeutic efficacy of Salmonella enteritidis-immune lymphokines against Salmonella enteritidis organ invasion in neonatal Leghorn chicks. Avian Dis. 39:21-27.
19. Kogut MH, McGruder ED, Hargis EM, Corrier DE, DeLoach JR. 1995. In vivo activation of heterophil function in chickens following injection with Salmonella enteritidis-immune lymphokines. J. Leukoc. Biol. 57:56-62.
20. Brogden KA, Ackerman M, McCray PB, Jr, Tuck BF. 2003. Antimicrobial peptides in animals and their role in host defenses. Int. J. Antimicrob. Agents 22:465-478.
21. Vizioli J, Salzet M. 2002. Antimicrobial peptides from animals: focus on invertebrates. Trends Pharmacol. Sci. 23:494-496.
22. Linde A, Ross CR, Davis EG, Dib L, Blecha F, Melgarejo T. 2008. Innate immunity and host defense peptides in veterinary medicine. J. Vet. Intern. Med. 22:247-265.
23. Ganz T. 2003. Defensins: antimicrobial peptides of innate immunity. Rev. Immunol. 3:710-720.
24. Bowdish DME, Davidson DJ, Lau YE, Lee K, Scott MG, Hancock REW. 2005. Impact of LL-37 on anti-infective immunity. J. Leukoc. Biol. 77: 451-459.
25. Hancock REW, Sahl H-G. 2006. Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies. Nat. Biotechnol. 24:1551-1557.
26. Mookherjee N, Hancock REW. 2007. Cationic host defense peptides: innate immune regulatory peptides as a novel approach for treating infections. Cell. Mol. Life Sci. 64:922-933.
27. Scott MG, Dullaghan E, Mookherjee N, Glavas N, Waldbrook M, Thompson A, Wang A, Lee K, Doria S, Hamill P, Yu JJ, Li Y, Donin O, Guarns MM, Finlay BB, North JR, Hancock REW. 2007. An antiinfective peptide that selectively modulates the innate immune response. Nat. Biotechnol. 25:465-472.
28. Hancock REW, Nijnik A, Philpott DJ. 2012. Modulating immunity as a therapy for bacterial infections. Nat. Rev. Microbiol. 10:243-254.
29. Finlay BB, Hancock REW. 2004. Can innate immunity be enhanced to treat microbial infections? Nat. Rev. Microbiol. 2:497-504.
30. Creagh EM, O'Neill LA. 2006. TLRs, NLRs, and RLRs: a trinity of pathogen sensors that co-operate in innate immunity. Trends Immunol. 27: 352-357.
31. Kawai T, Akira S. 2007. TLR signaling. Sem. Immunol. 19:24-32.
32. Henao-Mejia J, Elinav E, Strowig T, Flavell RA. 2012. Inflammasomes: far beyond inflammation. Nat. Immunol. 13:321-324.
33. Kogut MH, Chiang HS, Swaggerty CL, Pevzner IY, Zhou H. 2012. Gene expression analysis of Toll-like receptor pathways in heterophils from genetic lines that differ in their susceptibility to Salmonella enteritidis. Front. Genetics 3:121.
34. Erridge C. 2010. Endogenous ligands of TLR2 and TLR4: agonists or assistants? J. Leukoc. Biol. 87:989-999.
35. Lee CC, Avalos AM, Ploegh HL. 2012. Accessory molecules for Toll-like receptors and their function. Nat. Rev. Immunol. 12:168-179.
36. Akashi-Takamura S, Miyake K. 2008. TLR accessory molecules. Curr. Opin. Immunol. 20:420-425.
37. Lande R, Gregorio Facchinetti JV, Chatterjee B, Wang Y-H, Homey B, Cao W, Wang Y-H, Su B, Nestle FO, Zal T, Mellman I, Schroder J-M, Liu Y-J, Gilliet M. 2007. Plasmacytoid dendritic cells sense self-DNA coupled with antimicrobial peptide. Nature 449:564-569.
38. Setta A, Barrow PA, Kaiser P, Jones MA. 2012. Immune dynamics following infection of avian macrophages and epithelial cells with typhoidal and non-typhoidal Salmonella enterica serovars: bacterial invasion and persistence, nitric oxide and oxygen production, differential host gene expression, NF-κB signaling and cell cytotoxicity. Vet. Immunol. Immunopathol. 146:212-224.
39. Beal RK, Powers C, Wigley P, Barrow PA, Smith AL. 2004. Temporal dynamics of the cellular, humoral, and cytokine responses in chickens during primary and secondary infection with Salmonella enterica serovar Typhimurium. Avian Pathol. 17:571-588.
40. Berndt A, Wilhelm A, Jugert C, Pieper J, Sachse K, Methner U. 2007. Chicken cecum immune response to Salmonella enterica serovars of different levels of invasiveness. Infect. Immun. 75:5993-6007.
41. Haghighi HR, Abdul-Careem MF, Dara RA, Chambers JR, Sharif S. 2008. Cytokine gene expression in chicken cecal tonsils following treatment with probiotics and Salmonella infection. Vet. Microbiol. 126:225-233.
42. Withanage GS, Kaiser P, Wigley P, Powers C, Mastroeni P, Brooks H, Barrow P, Smith A, Maskell D. 2004. Rapid expression of chemokines and proinflammatory cytokines in newly hatched chickens infected with Salmonella enterica serovar Typhimurium. Infect. Immun. 72:2152-2159.
43. Shaughnessy RG, Meade KG, Cahalane S, Allan B, Reiman C, Callahan JJ, O'Farrelly C. 2009. Innate immune gene expression differentiates the early intestinal responses between Salmonella and Campylobacter. Vet. Immunol. Immunopathol. 132:191-198.
44. Fasina YO, Holt PS, Moran ET, Moore RW, Conner DE, McKee SR. 2008. Intestinal cytokine response of commercial source broiler chicks to Salmonella typhimurium infection. Poult. Sci. 87:1335-1346.
45. Cheeseman JH, Levy NA, Kaiser P, Lillehoj HS, Lamont SJ. 2009. Salmonella enteritidis-induced alteration of inflammatory CXCL chemokine messenger-RNA expression and histologic changes on the ceca of infected chicks. Avian Dis. 52:229-234.
46. Kaiser P, Hardt W. 2011. Salmonella typhimurium diarrhea: switching the mucosal epithelium from homeostasis to defense. Curr. Opin. Immunol. 23:456-463.
47. Rohn TT, Nelson LK, Sipes KM, Swain SD, Jutila KL, Quinn MT. 1999. Priming of human neutrophils by peroxynitrite: potential role in enhancement of the local inflammatory response. J. Leukoc. Biol. 65:59-70.
48. Condliff AM, Kitchen E, Chilvers ER. 1998. Neutrophil priming: pathophysiological consequences and underlying mechanisms. Clin. Sci. 94: 461-471.