In ovo treatment with CpG oligodeoxynucleotides decreases colonization of Salmonella enteriditis in broiler chickens

Veterinary Immunology and Immunopathology

Volumn 127, Issue 3-4, 2009, Pages 371-375

  MacKinnon, K M ^a   He, H ^a   Swaggerty, C L ^a   McReynolds, J L ^a   Genovese, K J ^a   Duke, S E ^a   Nerren, J R ^a   Kogut, M H ^a  

^a SOUTHERN PLAINS AGRICULTURAL RESEARCH CENTER   (United States)

Author keywords

Chicken; CpG ODN; In ovo; Innate immunity; Salmonella enteriditis

Indexed keywords

CPG OLIGODEOXYNUCLEOTIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL COLONIZATION; BASOPHIL DEGRANULATION; CELL ASSAY; CELL ISOLATION; EMBRYO; HATCHING; IMMUNOMODULATION; IMMUNOSTIMULATION; INFECTION RESISTANCE; INNATE IMMUNITY; INTESTINE CELL; NONHUMAN; RESPIRATORY BURST; SALMONELLA ENTERICA; SALMONELLA ENTERITIDIS; SALMONELLOSIS; SEROTYPE; THERAPY EFFECT; TREATMENT OUTCOME; TREATMENT RESPONSE;

ANIMALS; CHICK EMBRYO; CHICKENS; DISEASE SUSCEPTIBILITY; IMMUNITY, INNATE; OLIGODEOXYRIBONUCLEOTIDES; POULTRY DISEASES; SALMONELLA ENTERITIDIS; SALMONELLA INFECTIONS, ANIMAL;

AVES; GALLUS GALLUS; SALMONELLA ENTERICA; SALMONELLA ENTERITIDIS; SPONDIAS PURPUREA;

EID: 58249116642     PISSN: 01652427     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vetimm.2008.10.001     Document Type: Article

References (32)

1. Ameiss K.A., El Attrache J., Barri A., McElroy A.P., and Caldwell D.J. Influence of orally administered CpG-ODNs on the humoral response to bovine serum albumin (BSA) in chickens. Vet. Immunol. Immunopathol. 110 (2006) 257-267
2. Dalloul R.A., Lillehoj H.S., Okamura M., Xie H., Min W., Ding X., and Heckert R.A. In vivo effects of CpG oligodeoxynucleotide on eimeria infection in chickens. Avian Dis. 48 (2004) 783-790
3. FoodNet. Preliminary FoodNet data on the incidence of infection with pathogens transmitted commonly through food-10 states, 2007. MMWR 57 (2008) 366-370
4. Gomis S., Babiuk L., Godson D.L., Allan B., Thrush T., Townsend H., Willson P., Waters E., Hecker R., and Potter A. Protection of chickens against Escherichia coli infections by DNA containing CpG motifs. Infect. Immun. 71 (2003) 857-863
5. Gomis S., Babiuk L., Allan B., Willson P., Waters E., Ambrose N., Hecker R., and Potter A. Protection of neonatal chicks against a lethal challenge of Escherichia coli using DNA containing cytosine-phosphodiester-guanine motifs. Avian Dis. 48 (2004) 813-822
6. Gomis S., Babiuk L., Allan B., Willson P., Waters E., Hecker R., and Potter A. Protection of chickens against a lethal challenge of Escherichia coli by a vaccine containing CpG oligodeoxynucleotides as an adjuvant. Avian Dis. 51 (2007) 78-83
7. Harmon B.G. Avian heterophils in inflammation and disease resistance. Poult. Sci. 77 (1998) 972-977
8. He H., and Kogut M.H. CpG-ODN-induced nitric oxide production is mediated through clathrin-dependent endocytosis, endosomal maturation, and activation of PKC, MEK1/2 and p38 MAPK, and NF-kappaB pathways in avian macrophage cells (HD11). Cell Signal 15 (2003) 911-917
9. He H., Crippen T.L., Farnell M.B., and Kogut M.H. Identification of CpG oligodeoxynucleotide motifs that stimulate nitric oxide and cytokine production in avian macrophage and peripheral blood mononuclear cells. Dev. Comp. Immunol. 27 (2003) 621-627
10. He H., Lowry V.K., Ferro P.J., and Kogut M.H. CpG-oligodeoxynucleotide-stimulated chicken heterophil degranulation is serum cofactor and cell surface receptor dependent. Dev. Comp. Immunol. 29 (2005) 255-264
11. He H., Lowry V.K., Swaggerty C.L., Ferro P.J., and Kogut M.H. In vitro activation of chicken leukocytes and in vivo protection against Salmonella enteritidis organ invasion and peritoneal S. enteritidis infection-induced mortality in neonatal chickens by immunostimulatory CpG oligodeoxynucleotide. FEMS Immunol. Med. Microbiol. 43 (2005) 81-89
12. He H., Genovese K.J., Lowry V.K., Nisbet D.J., and Kogut M.H. Response of nitric oxide production to CpG oligodeoxynucleotides in turkey and chicken peripheral blood monocytes. FEMS Immunol. Med. Microbiol. 48 (2006) 99-106
13. He H., Genovese K.J., Swaggerty C.L., Nisbet D.J., and Kogut M.H. In vivo priming heterophil innate immune functions and increasing resistance to Salmonella enteritidis infection in neonatal chickens by immune stimulatory CpG oligodeoxynucleotides. Vet. Immunol. Immunopathol. 117 (2007) 275-283
14. He H., Genovese K.J., Swaggerty C.L., Nisbet D.J., and Kogut M.H. Differential induction of nitric oxide, degranulation, and oxidative burst activities in response to microbial agonist stimulations in monocytes and heterophils from young commercial turkeys. Vet. Immunol. Immunopathol. 123 (2008) 177-185
15. Hemmi H., Takeuchi O., Kawai T., Kaisho T., Sato S., Sanjo H., Matsumoto M., Hoshino K., Wagner H., Takeda K., and Akira S. A Toll-like receptor recognizes bacterial DNA. Nature 408 (2000) 740-745
16. Klinman D.M. Immunotherapeutic uses of CpG oligodeoxynucleotides. Nat. Rev. Immunol. 4 (2004) 249-258
17. Klinman D.M., Currie D., Gursel I., and Verthelyi D. Use of CpG oligodeoxynucleotides as immune adjuvants. Immunol. Rev. 199 (2004) 201-216
18. Kogut M.H., McGruder E.D., Hargis B.M., Corrier D.E., and DeLoach J.R. In vivo activation of heterophil function in chickens following injection with Salmonella enteritidis-immune lymphokines. J. Leukoc. Biol. 57 (1995) 56-62
19. Kogut M.H., Holtzapple C., Lowry V.K., Genovese K., and Stanker L.H. Functional responses of neonatal chicken and turkey heterophils following stimulation by inflammatory agonists. Am. J. Vet. Res. 59 (1998) 1404-1408
20. Kogut M.H., Iqbal M., He H., Philbin V., Kaiser P., and Smith A. Expression and function of Toll-like receptors in chicken heterophils. Dev. Comp. Immunol. 29 (2005) 791-807
21. Krieg A.M. CpG motifs in bacterial DNA and their immune effects. Annu. Rev. Immunol. 20 (2002) 709-760
22. Linghua Z., Xingshan T., and Fengzhen Z. Vaccination with newcastle disease vaccine and CpG oligodeoxynucleotides induces specific immunity and protection against newcastle disease virus in SPF chicken. Vet. Immunol. Immunopathol. 115 (2007) 216-222
23. National Research Council (U.S.). Subcommittee on Poultry Nutrition, NetLibrary, Inc., 1994. Nutrient Requirements of Poultry, National Academy Press, Washington, DC, pp. xiii, 155 p.
24. Patel B.A., Gomis S., Dar A., Willson P.J., Babiuk L.A., Potter A., Mutwiri G., and Tikoo S.K. Oligodeoxynucleotides containing CpG motifs (CpG-ODN) predominantly induce Th1-type immune response in neonatal chicks. Dev. Comp. Immunol. 32 (2008) 1041-1049
25. Roh H.J., Sung H.W., and Kwon H.M. Effects of DDA, CpG-ODN, and plasmid-encoded chicken IFN-gamma on protective immunity by a DNA vaccine against IBDV in chickens. J. Vet. Sci. 7 (2006) 361-368
26. Sadeyen J.R., Trotereau J., Velge P., Marly J., Beaumont C., Barrow P.A., Bumstead N., and Lalmanach A.C. Salmonella carrier state in chicken: comparison of expression of immune response genes between susceptible and resistant animals. Microbes. Infect. 6 (2004) 1278-1286
27. SAS, 2002. SAS Institute, Inc., In SAS, Cary, NC, USA.
28. Sharma J.M., and Burmester B.R. Resistance to Marek's disease at hatching in chickens vaccinated as embryos with the turkey herpesvirus. Avian Dis. 26 (1982) 134-149
29. Swaggerty C.L., Kogut M.H., Ferro P.J., Rothwell L., Pevzner I.Y., and Kaiser P. Differential cytokine mRNA expression in heterophils isolated from Salmonella-resistant and -susceptible chickens. Immunology 113 (2004) 139-148
30. Vleugels B., Ververken C., and Goddeeris B.M. Stimulatory effect of CpG sequences on humoral response in chickens. Poult. Sci. 81 (2002) 1317-1321
31. Wells L.L., Lowry V.K., DeLoach J.R., and Kogut M.H. Age-dependent phagocytosis and bactericidal activities of the chicken heterophil. Dev. Comp. Immunol. 22 (1998) 103-109
32. Xie H., Raybourne R.B., Babu U.S., Lillehoj H.S., and Heckert R.A. CpG-induced immunomodulation and intracellular bacterial killing in a chicken macrophage cell line. Dev. Comp. Immunol. 27 (2003) 823-834