Involvement of protein IF2 N domain in ribosomal subunit joining revealed from architecture and function of the full-length initiation factor

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 39, 2013, Pages 15656-15661

  Simonetti, Angelita ^a   Marzi, Stefano ^a   Billas, Isabelle M L ^a   Tsai, Albert ^b   Fabbretti, Attilio ^c   Myasnikov, Alexander G ^a   Roblin, Pierre ^d,e   Vaiana, Andrea C ^f   Hazemann, Isabelle ^a   Eiler, Daniel ^g   Steitz, Thomas A ^g,h   Puglisi, Joseph D ^b   Gualerzi, Claudio O ^c   Klaholz, Bruno P ^a  

^a UNIVERSITÉ DE STRASBOURG   (France)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF CAMERINO   (Italy)

^d SYNCHROTRON SOLEIL   (France)

^e CEMAGREF   (France)

^f MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY   (Germany)

^g YALE UNIVERSITY   (United States)

^h HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

Integrated structural biology; Protein synthesis

Indexed keywords

INITIATION FACTOR 2; TRANSFER RNA;

ARTICLE; CONFORMATION; CONTROLLED STUDY; CRYOELECTRON MICROSCOPY; CRYSTAL STRUCTURE; GEL PERMEATION CHROMATOGRAPHY; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN INTERACTION; RIBOSOME SUBUNIT; THERMUS THERMOPHILUS; X RAY DIFFRACTION;

INTEGRATED STRUCTURAL BIOLOGY; PROTEIN SYNTHESIS;

CRYOELECTRON MICROSCOPY; MODELS, MOLECULAR; MUTANT PROTEINS; PEPTIDE CHAIN INITIATION, TRANSLATIONAL; PROKARYOTIC INITIATION FACTOR-2; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RIBOSOME SUBUNITS; RIBOSOME SUBUNITS, LARGE, BACTERIAL; RIBOSOME SUBUNITS, SMALL, BACTERIAL; SCATTERING, SMALL ANGLE; STRUCTURE-ACTIVITY RELATIONSHIP; THERMUS THERMOPHILUS; X-RAY DIFFRACTION;

EID: 84884635539     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1309578110     Document Type: Article

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