Initiation factor 2 crystal structure reveals a different domain organization from eukaryotic initiation factor 5B and mechanism among translational GTPases

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 39, 2013, Pages 15662-15667

  Eiler, Daniel ^a   Lin, Jinzhong ^a   Simonetti, Angelita ^b   Klaholz, Bruno P ^b   Steitz, Thomas A ^a,c  

^a YALE UNIVERSITY   (United States)

^b UNIVERSITÉ DE STRASBOURG   (France)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INITIATION FACTOR; INITIATION FACTOR 2; INITIATION FACTOR 5B; TRANSFER RNA; UNCLASSIFIED DRUG;

ARTICLE; COMPLEX FORMATION; CONFORMATION; CRYOELECTRON MICROSCOPY; CRYSTAL STRUCTURE; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN SYNTHESIS; RIBOSOME SUBUNIT; THERMUS THERMOPHILUS; TRANSLATION INITIATION; X RAY CRYSTALLOGRAPHY;

CRYSTALLOGRAPHY, X-RAY; EUKARYOTIC INITIATION FACTORS; GTP PHOSPHOHYDROLASES; METHANOBACTERIUM; MODELS, MOLECULAR; PROKARYOTIC INITIATION FACTOR-2; PROTEIN BIOSYNTHESIS; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; THERMUS THERMOPHILUS;

EID: 84884645185     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1309360110     Document Type: Article

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