Structure-guided inhibitor design expands the scope of analog-sensitive kinase technology

ACS Chemical Biology

Volumn 8, Issue 9, 2013, Pages 1931-1938

  Zhang, Chao ^a,f   Lopez, Michael S ^a,e,f   Dar, Arvin C ^a,g   Ladow, Eva ^b   Finkbeiner, Steven ^b   Yun, Cai Hong ^c   Eck, Michael J ^c   Shokat, Kevan M ^a,d  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b GLADSTONE INSTITUTE OF NEUROLOGICAL DISEASE   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^g MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANALOG SENSITIVE KINASE INHIBITOR; PHOSPHOTRANSFERASE; PHOSPHOTRANSFERASE INHIBITOR; PROTEIN KINASE; UNCLASSIFIED DRUG;

ARTICLE; DRUG DESIGN; DRUG MECHANISM; DRUG POTENCY; DRUG SELECTIVITY; DRUG STRUCTURE; ENZYME ENGINEERING; ENZYME INHIBITION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TECHNOLOGY; X RAY CRYSTALLOGRAPHY;

CRYSTALLOGRAPHY, X-RAY; DRUG DESIGN; HUMANS; MODELS, MOLECULAR; PROTEIN KINASE INHIBITORS; PROTEIN KINASES;

EID: 84884622576     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/cb400376p     Document Type: Article

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