Mutant tyrosine kinases with unnatural nucleotide specificity retain the structure and phospho-acceptor specificity of the wild-type enzyme

Chemistry and Biology

Volumn 9, Issue 1, 2002, Pages 25-33

  Witucki, Laurie A ^a   Huang, Xin ^b   Shah, Kavita ^a   Liu, Yi ^a   Kyin, Saw ^c   Eck, Michael J ^b   Shokat, Kevan M ^a,d  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b DANA FARBER CANCER INSTITUTE   (United States)

^c PRINCETON UNIVERSITY   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PEPTIDE FRAGMENT; PEPTIDE LIBRARY; PROTEIN TYROSINE KINASE;

AMINO ACID SEQUENCE; ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; ENZYME SPECIFICITY; GENETICS; METABOLISM; MOLECULAR GENETICS; MUTATION; PHOSPHORYLATION; PROTEIN ENGINEERING; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PEPTIDE FRAGMENTS; PEPTIDE LIBRARY; PHOSPHORYLATION; PROTEIN ENGINEERING; SRC-FAMILY KINASES; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

EID: 0036008090     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-5521(02)00091-1     Document Type: Article

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