Cellular senescence in yeast is regulated by rDNA noncoding transcription

Current Biology

Volumn 23, Issue 18, 2013, Pages 1794-1798

  Saka, Kimiko ^a   Ide, Satoru ^a   Ganley, Austen R D ^a,b   Kobayashi, Takehiko ^a  

^a GRADUATE UNIVERSITY FOR ADVANCED STUDIES   (Japan)

^b MASSEY UNIVERSITY   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

SACCHAROMYCES CEREVISIAE;

RIBOSOME DNA;

ARTICLE; BIOLOGICAL MODEL; CELL AGING; CYTOLOGY; GENETIC TRANSCRIPTION; GENETICS; GENOMIC INSTABILITY; LONGEVITY; PHYSIOLOGY; SACCHAROMYCES CEREVISIAE;

CELL AGING; DNA, RIBOSOMAL; GENOMIC INSTABILITY; LONGEVITY; MODELS, GENETIC; SACCHAROMYCES CEREVISIAE; TRANSCRIPTION, GENETIC;

EID: 84884594512     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cub.2013.07.048     Document Type: Article

References (34)

1. W.C. Burhans, and M. Weinberger DNA replication stress, genome instability and aging Nucleic Acids Res. 35 2007 7545 7556
2. T. Kobayashi A new role of the rDNA and nucleolus in the nucleus - rDNA instability maintains genome integrity Bioessays 30 2008 267 272
3. M. Kaeberlein Lessons on longevity from budding yeast Nature 464 2010 513 519
4. T. Kobayashi The replication fork barrier site forms a unique structure with Fob1p and inhibits the replication fork Mol. Cell. Biol. 23 2003 9178 9188
5. T. Kobayashi, D.J. Heck, M. Nomura, and T. Horiuchi Expansion and contraction of ribosomal DNA repeats in Saccharomyces cerevisiae: requirement of replication fork blocking (Fob1) protein and the role of RNA polymerase I Genes Dev. 12 1998 3821 3830
6. P.A. Defossez, R. Prusty, M. Kaeberlein, S.J. Lin, P. Ferrigno, P.A. Silver, R.L. Keil, and L. Guarente Elimination of replication block protein Fob1 extends the life span of yeast mother cells Mol. Cell 3 1999 447 455
7. Y. Takeuchi, T. Horiuchi, and T. Kobayashi Transcription-dependent recombination and the role of fork collision in yeast rDNA Genes Dev. 17 2003 1497 1506
8. S.-I. Imai, C.M. Armstrong, M. Kaeberlein, and L. Guarente Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase Nature 403 2000 795 800
9. D. Moazed Enzymatic activities of Sir2 and chromatin silencing Curr. Opin. Cell Biol. 13 2001 232 238
10. M. Kaeberlein, M. McVey, and L. Guarente The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms Genes Dev. 13 1999 2570 2580
11. T. Kobayashi, T. Horiuchi, P. Tongaonkar, L. Vu, and M. Nomura SIR2 regulates recombination between different rDNA repeats, but not recombination within individual rRNA genes in yeast Cell 117 2004 441 453
12. D.A. Sinclair, and L. Guarente Extrachromosomal rDNA circles - a cause of aging in yeast Cell 91 1997 1033 1042
13. A.R.D. Ganley, S. Ide, K. Saka, and T. Kobayashi The effect of replication initiation on gene amplification in the rDNA and its relationship to aging Mol. Cell 35 2009 683 693
14. T. Kobayashi Regulation of ribosomal RNA gene copy number and its role in modulating genome integrity and evolutionary adaptability in yeast Cell. Mol. Life Sci. 68 2011 1395 1403
15. E.X. Kwan, E.J. Foss, S. Tsuchiyama, G.M. Alvino, L. Kruglyak, M. Kaeberlein, M.K. Raghuraman, B.J. Brewer, B.K. Kennedy, and A. Bedalov A natural polymorphism in rDNA replication origins links origin activation with calorie restriction and lifespan PLoS Genet. 9 2013 e1003329
16. W. Dang, K.K. Steffen, R. Perry, J.A. Dorsey, F.B. Johnson, A. Shilatifard, M. Kaeberlein, B.K. Kennedy, and S.L. Berger Histone H4 lysine 16 acetylation regulates cellular lifespan Nature 459 2009 802 807
17. N. Erjavec, L. Larsson, J. Grantham, and T. Nyström Accelerated aging and failure to segregate damaged proteins in Sir2 mutants can be suppressed by overproducing the protein aggregation-remodeling factor Hsp104p Genes Dev. 21 2007 2410 2421
18. J.R. Delaney, G.L. Sutphin, B. Dulken, S. Sim, J.R. Kim, B. Robison, J. Schleit, C.J. Murakami, D. Carr, and E.H. An Sir2 deletion prevents lifespan extension in 32 long-lived mutants Aging Cell 10 2011 1089 1091
19. S.W. Stumpferl, S.E. Brand, J.C. Jiang, B. Korona, A. Tiwari, J. Dai, J.-G. Seo, and S.M. Jazwinski Natural genetic variation in yeast longevity Genome Res. 22 2012 1963 1973
20. T. Kobayashi, and A.R.D. Ganley Recombination regulation by transcription-induced cohesin dissociation in rDNA repeats Science 309 2005 1581 1584
21. J.S. Smith, and J.D. Boeke An unusual form of transcriptional silencing in yeast ribosomal DNA Genes Dev. 11 1997 241 254
22. J.S. Flick, and M. Johnston Two systems of glucose repression of the GAL1 promoter in Saccharomyces cerevisiae Mol. Cell. Biol. 10 1990 4757 4769
23. C.E. Fritze, K. Verschueren, R. Strich, and R. Easton Esposito Direct evidence for SIR2 modulation of chromatin structure in yeast rDNA EMBO J. 16 1997 6495 6509
24. M. Bodmer-Glavas, K. Edler, and A. Barberis RNA polymerase II and III transcription factors can stimulate DNA replication by modifying origin chromatin structures Nucleic Acids Res. 29 2001 4570 4580
25. D.L. Lindstrom, C.K. Leverich, K.A. Henderson, and D.E. Gottschling Replicative age induces mitotic recombination in the ribosomal RNA gene cluster of Saccharomyces cerevisiae PLoS Genet. 7 2011 e1002015
26. F. Wyers, M. Rougemaille, G. Badis, J.-C. Rousselle, M.-E. Dufour, J. Boulay, B. Régnault, F. Devaux, A. Namane, and B. Séraphin Cryptic pol II transcripts are degraded by a nuclear quality control pathway involving a new poly(A) polymerase Cell 121 2005 725 737
27. J.M. Houseley, K. Kotovic, A. El Hage, and D. Tollervey Trf4 targets ncRNAs from telomeric and rDNA spacer regions and functions in rDNA copy number control EMBO J. 26 2007 4996 5006
28. T. Kobayashi How does genome instability affect lifespan? roles of rDNA and telomeres Genes Cells 16 2011 617 624
29. S. Ide, T. Miyazaki, H. Maki, and T. Kobayashi Abundance of ribosomal RNA gene copies maintains genome integrity Science 327 2010 693 696
30. D.M. Stults, M.W. Killen, E.P. Williamson, J.S. Hourigan, H.D. Vargas, S.M. Arnold, J.A. Moscow, and A.J. Pierce Human rRNA gene clusters are recombinational hotspots in cancer Cancer Res. 69 2009 9096 9104
31. T.H. Eickbush, and D.G. Eickbush Finely orchestrated movements: evolution of the ribosomal RNA genes Genetics 175 2007 477 485
32. C. Kaiser, S. Michaelis, and A. Mitchell Methods in Yeast Genetics 1994 Cold Spring Harbor Laboratory Press Cold Spring Harbor
33. A. Laferté, E. Favry, A. Sentenac, M. Riva, C. Carles, and S. Chédin The transcriptional activity of RNA polymerase I is a key determinant for the level of all ribosome components Genes Dev. 20 2006 2030 2040
34. B.K. Kennedy, N.R. Austriaco Jr., and L. Guarente Daughter cells of Saccharomyces cerevisiae from old mothers display a reduced life span J. Cell Biol. 127 1994 1985 1993