-
1
-
-
0030814774
-
The canalicular multispecific organic anion transporter and conjugated hyperbilirubinemia in rat and man
-
Paulusma CC, Oude Elferink RP. The canalicular multispecific organic anion transporter and conjugated hyperbilirubinemia in rat and man. J Mol Med 1997; 75: 420-428.
-
(1997)
J Mol Med
, vol.75
, pp. 420-428
-
-
Paulusma, C.C.1
Oude Elferink, R.P.2
-
2
-
-
0040761368
-
CDNA cloning of the hepatocyte canalicular isoform of the multidrug resistance protein, cMrp, reveals a novel conjugate export pump deficient in hyperbilirubinemic mutant rats
-
Buchler M, Konig J, Brom M, Kartenbeck J, Spring H, Horie T et al. cDNA cloning of the hepatocyte canalicular isoform of the multidrug resistance protein, cMrp, reveals a novel conjugate export pump deficient in hyperbilirubinemic mutant rats. J Biol Chem 1996; 271: 15091-15098.
-
(1996)
J Biol Chem
, vol.271
, pp. 15091-15098
-
-
Buchler, M.1
Konig, J.2
Brom, M.3
Kartenbeck, J.4
Spring, H.5
Horie, T.6
-
4
-
-
0033936291
-
Vinblastine and sulfinpyrazone export by the multidrug resistance protein MRP2 is associated with glutathione export
-
Evers R, de Haas M, Sparidans R, Beijnen J, Wielinga PR, Lankelma J et al. Vinblastine and sulfinpyrazone export by the multidrug resistance protein MRP2 is associated with glutathione export. Br J Cancer 2000; 83: 375-383.
-
(2000)
Br J Cancer
, vol.83
, pp. 375-383
-
-
Evers, R.1
De Haas, M.2
Sparidans, R.3
Beijnen, J.4
Wielinga, P.R.5
Lankelma, J.6
-
5
-
-
33846706434
-
The apical conjugate efflux pump ABCC2 (MRP2)
-
Nies AT, Keppler D. The apical conjugate efflux pump ABCC2 (MRP2). Pflugers Arch 2007; 453: 643-659.
-
(2007)
Pflugers Arch
, vol.453
, pp. 643-659
-
-
Nies, A.T.1
Keppler, D.2
-
6
-
-
77954358310
-
ABCC2/Abcc2: A multispecific transporter with dominant excretory functions
-
Jemnitz K, Heredi-Szabo K, Janossy J, Ioja E, Vereczkey L, Krajcsi P. ABCC2/Abcc2: a multispecific transporter with dominant excretory functions. Drug Metab Rev 2010; 42: 402-436.
-
(2010)
Drug Metab Rev
, vol.42
, pp. 402-436
-
-
Jemnitz, K.1
Heredi-Szabo, K.2
Janossy, J.3
Ioja, E.4
Vereczkey, L.5
Krajcsi, P.6
-
7
-
-
0033361943
-
Genomic structure of the canalicular multispecific organic anion-transporter gene (MRP2/cMOAT) and mutations in the ATP-binding-cassette region in Dubin-Johnson syndrome
-
Toh S, Wada M, Uchiumi T, Inokuchi A, Makino Y, Horie Y et al. Genomic structure of the canalicular multispecific organic anion-transporter gene (MRP2/cMOAT) and mutations in the ATP-binding-cassette region in Dubin-Johnson syndrome. Am J Hum Genet 1999; 64: 739-746.
-
(1999)
Am J Hum Genet
, vol.64
, pp. 739-746
-
-
Toh, S.1
Wada, M.2
Uchiumi, T.3
Inokuchi, A.4
Makino, Y.5
Horie, Y.6
-
8
-
-
33745929357
-
Pharmacogenetic characteristics of indinavir, zidovudine, and lamivudine therapy in HIV-infected adults: A pilot study
-
Anderson PL, Lamba J, Aquilante CL, Schuetz E, Fletcher CV. Pharmacogenetic characteristics of indinavir, zidovudine, and lamivudine therapy in HIV-infected adults: a pilot study. J Acquir Immune Defic Syndr 2006; 42: 441-449.
-
(2006)
J Acquir Immune Defic Syndr
, vol.42
, pp. 441-449
-
-
Anderson, P.L.1
Lamba, J.2
Aquilante, C.L.3
Schuetz, E.4
Fletcher, C.V.5
-
9
-
-
40549085349
-
Influence of genetic polymorphisms on intestinal expression and rifampicin-type induction of ABCC2 and on bioavailability of talinolol
-
Haenisch S, May K, Wegner D, Caliebe A, Cascorbi I, Siegmund W. Influence of genetic polymorphisms on intestinal expression and rifampicin-type induction of ABCC2 and on bioavailability of talinolol. Pharmacogenet Genomics 2008; 18: 357-365.
-
(2008)
Pharmacogenet Genomics
, vol.18
, pp. 357-365
-
-
Haenisch, S.1
May, K.2
Wegner, D.3
Caliebe, A.4
Cascorbi, I.5
Siegmund, W.6
-
10
-
-
33847249931
-
Influence of polymorphisms of ABCB1 and ABCC2 on mRNA and protein expression in normal and cancerous kidney cortex
-
Haenisch S, Zimmermann U, Dazert E, Wruck CJ, Dazert P, Siegmund W et al. Influence of polymorphisms of ABCB1 and ABCC2 on mRNA and protein expression in normal and cancerous kidney cortex. Pharmacogenomics J 2007; 7: 56-65.
-
(2007)
Pharmacogenomics J
, vol.7
, pp. 56-65
-
-
Haenisch, S.1
Zimmermann, U.2
Dazert, E.3
Wruck, C.J.4
Dazert, P.5
Siegmund, W.6
-
11
-
-
3543004158
-
Characterization of the cellular localization, expression level, and function of SNP variants of MRP2/ ABCC2
-
Hirouchi M, Suzuki H, Itoda M, Ozawa S, Sawada J, Ieiri I et al. Characterization of the cellular localization, expression level, and function of SNP variants of MRP2/ ABCC2. Pharm Res 2004; 21: 742-748.
-
(2004)
Pharm Res
, vol.21
, pp. 742-748
-
-
Hirouchi, M.1
Suzuki, H.2
Itoda, M.3
Ozawa, S.4
Sawada, J.5
Ieiri, I.6
-
12
-
-
33745901941
-
Interindividual variability of canalicular ATP-binding-cassette (ABC)-transporter expression in human liver
-
Meier Y, Pauli-Magnus C, Zanger UM, Klein K, Schaeffeler E, Nussler AK et al. Interindividual variability of canalicular ATP-binding-cassette (ABC)-transporter expression in human liver. Hepatology 2006; 44: 62-74.
-
(2006)
Hepatology
, vol.44
, pp. 62-74
-
-
Meier, Y.1
Pauli-Magnus, C.2
Zanger, U.M.3
Klein, K.4
Schaeffeler, E.5
Nussler, A.K.6
-
13
-
-
41849115973
-
Methotrexate (MTX) pathway gene polymorphisms and their effects on MTX toxicity in Caucasian and African American patients with rheumatoid arthritis
-
Ranganathan P, Culverhouse R, Marsh S, Mody A, Scott-Horton TJ, Brasington R et al. Methotrexate (MTX) pathway gene polymorphisms and their effects on MTX toxicity in Caucasian and African American patients with rheumatoid arthritis. J Rheumatol 2008; 35: 572-579.
-
(2008)
J Rheumatol
, vol.35
, pp. 572-579
-
-
Ranganathan, P.1
Culverhouse, R.2
Marsh, S.3
Mody, A.4
Scott-Horton, T.J.5
Brasington, R.6
-
14
-
-
33845226137
-
Association between ABCC2 gene haplotypes and tenofovir-induced proximal tubulopathy
-
Izzedine H, Hulot JS, Villard E, Goyenvalle C, Dominguez S, Ghosn J et al. Association between ABCC2 gene haplotypes and tenofovir-induced proximal tubulopathy. J Infect Dis 2006; 194: 1481-1491.
-
(2006)
J Infect Dis
, vol.194
, pp. 1481-1491
-
-
Izzedine, H.1
Hulot, J.S.2
Villard, E.3
Goyenvalle, C.4
Dominguez, S.5
Ghosn, J.6
-
15
-
-
33644876141
-
NAD(P)H oxidase and multidrug resistance protein genetic polymorphisms are associated with doxorubicin-induced cardiotoxicity
-
Wojnowski L, Kulle B, Schirmer M, Schluter G, Schmidt A, Rosenberger A et al. NAD(P)H oxidase and multidrug resistance protein genetic polymorphisms are associated with doxorubicin-induced cardiotoxicity. Circulation 2005; 112: 3754-3762.
-
(2005)
Circulation
, vol.112
, pp. 3754-3762
-
-
Wojnowski, L.1
Kulle, B.2
Schirmer, M.3
Schluter, G.4
Schmidt, A.5
Rosenberger, A.6
-
16
-
-
0034105939
-
Characterization of the 50-flanking region of the human multidrug resistance protein 2 (MRP2) gene and its regulation in comparison with the multidrug resistance protein 3 (MRP3) gene
-
Stockel B, Konig J, Nies AT, Cui Y, Brom M, Keppler D. Characterization of the 50-flanking region of the human multidrug resistance protein 2 (MRP2) gene and its regulation in comparison with the multidrug resistance protein 3 (MRP3) gene. Eur J Biochem 2000; 267: 1347-1358.
-
(2000)
Eur J Biochem
, vol.267
, pp. 1347-1358
-
-
Stockel, B.1
Konig, J.2
Nies, A.T.3
Cui, Y.4
Brom, M.5
Keppler, D.6
-
17
-
-
0032745443
-
The human multidrug resistance protein 2 gene: Functional characterization of the 50-flanking region and expression in hepatic cells
-
Tanaka T, Uchiumi T, Hinoshita E, Inokuchi A, Toh S, Wada M et al. The human multidrug resistance protein 2 gene: functional characterization of the 50-flanking region and expression in hepatic cells. Hepatology 1999; 30: 1507-1512.
-
(1999)
Hepatology
, vol.30
, pp. 1507-1512
-
-
Tanaka, T.1
Uchiumi, T.2
Hinoshita, E.3
Inokuchi, A.4
Toh, S.5
Wada, M.6
-
18
-
-
58649088927
-
Interaction of hepatocyte nuclear factors in transcriptional regulation of tissue specific hormonal expression of human multidrug resistance-associated protein 2 (abcc2)
-
Qadri I, Hu LJ, Iwahashi M, Al-Zuabi S, Quattrochi LC, Simon FR. Interaction of hepatocyte nuclear factors in transcriptional regulation of tissue specific hormonal expression of human multidrug resistance-associated protein 2 (abcc2). Toxicol Appl Pharmacol 2009; 234: 281-292.
-
(2009)
Toxicol Appl Pharmacol
, vol.234
, pp. 281-292
-
-
Qadri, I.1
Hu, L.J.2
Iwahashi, M.3
Al-Zuabi, S.4
Quattrochi, L.C.5
Simon, F.R.6
-
19
-
-
33750346955
-
Multidrug resistance protein 2 genetic polymorphisms influence mycophenolic acid exposure in renal allograft recipients
-
Naesens M, Kuypers DR, Verbeke K, Vanrenterghem Y. Multidrug resistance protein 2 genetic polymorphisms influence mycophenolic acid exposure in renal allograft recipients. Transplantation 2006; 82: 1074-1084.
-
(2006)
Transplantation
, vol.82
, pp. 1074-1084
-
-
Naesens, M.1
Kuypers, D.R.2
Verbeke, K.3
Vanrenterghem, Y.4
-
20
-
-
34248547635
-
MRP2 haplotypes confer differential susceptibility to toxic liver injury
-
Choi JH, Ahn BM, Yi J, Lee JH, Nam SW, Chon CY et al. MRP2 haplotypes confer differential susceptibility to toxic liver injury. Pharmacogenet Genomics 2007; 17: 403-415.
-
(2007)
Pharmacogenet Genomics
, vol.17
, pp. 403-415
-
-
Choi, J.H.1
Ahn, B.M.2
Yi, J.3
Lee, J.H.4
Nam, S.W.5
Chon, C.Y.6
-
21
-
-
33846230114
-
Genetic susceptibility to diclofenac-induced hepatotoxicity: Contribution of UGT2B7, CYP2C8, and ABCC2 genotypes
-
Daly AK, Aithal GP, Leathart JB, Swainsbury RA, Dang TS, Day CP. Genetic susceptibility to diclofenac-induced hepatotoxicity: contribution of UGT2B7, CYP2C8, and ABCC2 genotypes. Gastroenterology 2007; 132: 272-281.
-
(2007)
Gastroenterology
, vol.132
, pp. 272-281
-
-
Daly, A.K.1
Aithal, G.P.2
Leathart, J.B.3
Swainsbury, R.A.4
Dang, T.S.5
Day, C.P.6
-
22
-
-
55549141199
-
Association of ATP-binding cassette, sub-family C, number 2 (ABCC2) genotype with pharmacokinetics of irinotecan in Japanese patients with metastatic colorectal cancer treated with irinotecan plus infusional 5-fluorouracil/leucovorin (FOLFIRI)
-
Fujita K, Nagashima F, Yamamoto W, Endo H, Sunakawa Y, Yamashita K et al. Association of ATP-binding cassette, sub-family C, number 2 (ABCC2) genotype with pharmacokinetics of irinotecan in Japanese patients with metastatic colorectal cancer treated with irinotecan plus infusional 5-fluorouracil/ leucovorin (FOLFIRI). Biol Pharm Bull 2008; 31: 2137-2142.
-
(2008)
Biol Pharm Bull
, vol.31
, pp. 2137-2142
-
-
Fujita, K.1
Nagashima, F.2
Yamamoto, W.3
Endo, H.4
Sunakawa, Y.5
Yamashita, K.6
-
23
-
-
10844238220
-
Effects of polymorphisms of MDR1, MRP1, and MRP2 genes on their mRNA expression levels in duodenal enterocytes of healthy Japanese subjects
-
Moriya Y, Nakamura T, Horinouchi M, Sakaeda T, Tamura T, Aoyama N et al. Effects of polymorphisms of MDR1, MRP1, and MRP2 genes on their mRNA expression levels in duodenal enterocytes of healthy Japanese subjects. Biol Pharm Bull 2002; 25: 1356-1359.
-
(2002)
Biol Pharm Bull
, vol.25
, pp. 1356-1359
-
-
Moriya, Y.1
Nakamura, T.2
Horinouchi, M.3
Sakaeda, T.4
Tamura, T.5
Aoyama, N.6
-
24
-
-
34250825286
-
Associations of ABCB1, ABCC2, and ABCG2 polymorphisms with irinotecan-pharmacokinetics and clinical outcome in patients with advanced non-small cell lung cancer
-
Han JY, Lim HS, Yoo YK, Shin ES, Park YH, Lee SY et al. Associations of ABCB1, ABCC2, and ABCG2 polymorphisms with irinotecan-pharmacokinetics and clinical outcome in patients with advanced non-small cell lung cancer. Cancer 2007; 110: 138-147.
-
(2007)
Cancer
, vol.110
, pp. 138-147
-
-
Han, J.Y.1
Lim, H.S.2
Yoo, Y.K.3
Shin, E.S.4
Park, Y.H.5
Lee, S.Y.6
-
25
-
-
36148991372
-
Influence of SLCO1B1, 1B3, 2B1 and ABCC2 genetic polymorphisms on mycophenolic acid pharmacokinetics in Japanese renal transplant recipients
-
Miura M, Satoh S, Inoue K, Kagaya H, Saito M, Inoue T et al. Influence of SLCO1B1, 1B3, 2B1 and ABCC2 genetic polymorphisms on mycophenolic acid pharmacokinetics in Japanese renal transplant recipients. Eur J Clin Pharmacol 2007; 63: 1161-1169.
-
(2007)
Eur J Clin Pharmacol
, vol.63
, pp. 1161-1169
-
-
Miura, M.1
Satoh, S.2
Inoue, K.3
Kagaya, H.4
Saito, M.5
Inoue, T.6
-
26
-
-
33845893608
-
Pharmacogenetics of irinotecan: Clinical perspectives on the utility of genotyping
-
Innocenti F, Ratain MJ. Pharmacogenetics of irinotecan: clinical perspectives on the utility of genotyping. Pharmacogenomics 2006; 7: 1211-1221.
-
(2006)
Pharmacogenomics
, vol.7
, pp. 1211-1221
-
-
Innocenti, F.1
Ratain, M.J.2
-
27
-
-
33748994272
-
Role for drug transporters beyond tumor resistance: Hepatic functional imaging and genotyping of multidrug resistance transporters for the prediction of irinotecan toxicity
-
Kroetz DL. Role for drug transporters beyond tumor resistance: hepatic functional imaging and genotyping of multidrug resistance transporters for the prediction of irinotecan toxicity. J Clin Oncol 2006; 24: 4225-4227.
-
(2006)
J Clin Oncol
, vol.24
, pp. 4225-4227
-
-
Kroetz, D.L.1
-
28
-
-
33745020069
-
Disposition of 9-nitrocamptothecin and its 9-aminocamptothecin metabolite in relation to ABC transporter genotypes
-
Zamboni WC, Ramanathan RK, McLeod HL, Mani S, Potter DM, Strychor S et al. Disposition of 9-nitrocamptothecin and its 9-aminocamptothecin metabolite in relation to ABC transporter genotypes. Invest New Drugs 2006; 24: 393-401.
-
(2006)
Invest New Drugs
, vol.24
, pp. 393-401
-
-
Zamboni, W.C.1
Ramanathan, R.K.2
McLeod, H.L.3
Mani, S.4
Potter, D.M.5
Strychor, S.6
-
29
-
-
66849111193
-
Comprehensive pharmacogenetic analysis of irinotecan neutropenia and pharmacokinetics
-
Innocenti F, Kroetz DL, Schuetz E, Dolan ME, Ramirez J, Relling M et al. Comprehensive pharmacogenetic analysis of irinotecan neutropenia and pharmacokinetics. J Clin Oncol 2009; 27: 2604-2614.
-
(2009)
J Clin Oncol
, vol.27
, pp. 2604-2614
-
-
Innocenti, F.1
Kroetz, D.L.2
Schuetz, E.3
Dolan, M.E.4
Ramirez, J.5
Relling, M.6
-
30
-
-
65649090669
-
Association of the c.3972C4T variant of the multidrug resistance-associated protein 2 Gene (MRP2/ABCC2) with susceptibility to bile duct cancer
-
Hoblinger A, Grunhage F, Sauerbruch T, Lammert F. Association of the c.3972C4T variant of the multidrug resistance-associated protein 2 Gene (MRP2/ABCC2) with susceptibility to bile duct cancer. Digestion 2009; 80: 36-39.
-
(2009)
Digestion
, vol.80
, pp. 36-39
-
-
Hoblinger, A.1
Grunhage, F.2
Sauerbruch, T.3
Lammert, F.4
-
31
-
-
79953796265
-
Association of ABCC2 polymorphisms with platinum-based chemotherapy response and severe toxicity in non-small cell lung cancer patients
-
Han B, Gao G, Wu W, Gao Z, Zhao X, Li L et al. Association of ABCC2 polymorphisms with platinum-based chemotherapy response and severe toxicity in non-small cell lung cancer patients. Lung Cancer 2011; 72: 238-243.
-
(2011)
Lung Cancer
, vol.72
, pp. 238-243
-
-
Han, B.1
Gao, G.2
Wu, W.3
Gao, Z.4
Zhao, X.5
Li, L.6
-
32
-
-
0038612980
-
Natural variation in human membrane transporter genes reveals evolutionary and functional constraints
-
Leabman MK, Huang CC, DeYoung J, Carlson EJ, Taylor TR, de la Cruz M et al. Natural variation in human membrane transporter genes reveals evolutionary and functional constraints. Proc Natl Acad Sci USA 2003; 100: 5896-5901.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 5896-5901
-
-
Leabman, M.K.1
Huang, C.C.2
Deyoung, J.3
Carlson, E.J.4
Taylor, T.R.5
De La Cruz, M.6
-
33
-
-
0035078440
-
Fluorescence polarization in homogeneous nucleic acid analysis II: 50-nuclease assay
-
Latif S, Bauer-Sardina I, Ranade K, Livak KJ, Kwok PY. Fluorescence polarization in homogeneous nucleic acid analysis II: 50-nuclease assay. Genome Res 2001; 11: 436-440.
-
(2001)
Genome Res
, vol.11
, pp. 436-440
-
-
Latif, S.1
Bauer-Sardina, I.2
Ranade, K.3
Livak, K.J.4
Kwok, P.Y.5
-
34
-
-
33846012498
-
Irinotecan-induced diarrhea: Functional significance of the polymorphic ABCC2 transporter protein
-
de Jong FA, Scott-Horton TJ, Kroetz DL, McLeod HL, Friberg LE, Mathijssen RH et al. Irinotecan-induced diarrhea: functional significance of the polymorphic ABCC2 transporter protein. Clin Pharmacol Ther 2007; 81: 42-49.
-
(2007)
Clin Pharmacol Ther
, vol.81
, pp. 42-49
-
-
De Jong, F.A.1
Scott-Horton, T.J.2
Kroetz, D.L.3
McLeod, H.L.4
Friberg, L.E.5
Mathijssen, R.H.6
-
35
-
-
78649320874
-
Impact of ABCC2 haplotypes on transcriptional and posttranscriptional gene regulation and function
-
Laechelt S, Turrini E, Ruehmkorf A, Siegmund W, Cascorbi I, Haenisch S. Impact of ABCC2 haplotypes on transcriptional and posttranscriptional gene regulation and function. Pharmacogenomics J 2011; 11: 25-34.
-
(2011)
Pharmacogenomics J
, vol.11
, pp. 25-34
-
-
Laechelt, S.1
Turrini, E.2
Ruehmkorf, A.3
Siegmund, W.4
Cascorbi, I.5
Haenisch, S.6
-
36
-
-
67149124051
-
Non-response to antiepileptic pharmacotherapy is associated with the ABCC2-24C4T polymorphism in young and adult patients with epilepsy
-
Ufer M, Mosyagin I, Muhle H, Jacobsen T, Haenisch S, Hasler R et al. Non-response to antiepileptic pharmacotherapy is associated with the ABCC2-24C4T polymorphism in young and adult patients with epilepsy. Pharmacogenet Genomics 2009; 19: 353-362.
-
(2009)
Pharmacogenet Genomics
, vol.19
, pp. 353-362
-
-
Ufer, M.1
Mosyagin, I.2
Muhle, H.3
Jacobsen, T.4
Haenisch, S.5
Hasler, R.6
-
37
-
-
24644452967
-
MDR1, MRP1 and MRP2 genotypes and in vitro chemosensitivity in Japanese patients with colorectal adenocarcinomas
-
Nishioka C, Sakaeda T, Nakamura T, Moriya Y, Okamura N, Tamura T et al. MDR1, MRP1 and MRP2 genotypes and in vitro chemosensitivity in Japanese patients with colorectal adenocarcinomas. Kobe J Med Sci 2004; 50: 181-188.
-
(2004)
Kobe J Med Sci
, vol.50
, pp. 181-188
-
-
Nishioka, C.1
Sakaeda, T.2
Nakamura, T.3
Moriya, Y.4
Okamura, N.5
Tamura, T.6
-
38
-
-
22344452418
-
Variable expression of MRP2 (ABCC2) in human placenta: Influence of gestational age and cellular differentiation
-
Meyer zu Schwabedissen HE, Jedlitschky G, Gratz M, Haenisch S, Linnemann K, Fusch C et al. Variable expression of MRP2 (ABCC2) in human placenta: influence of gestational age and cellular differentiation. Drug Metab Dispos 2005; 33: 896-904.
-
(2005)
Drug Metab Dispos
, vol.33
, pp. 896-904
-
-
Meyer Zu Schwabedissen, H.E.1
Jedlitschky, G.2
Gratz, M.3
Haenisch, S.4
Linnemann, K.5
Fusch, C.6
-
39
-
-
84855965754
-
Lack of association between ABCC2 gene variants and treatment response in epilepsy
-
Hilger E, Reinthaler EM, Stogmann E, Hotzy C, Pataraia E, Baumgartner C et al. Lack of association between ABCC2 gene variants and treatment response in epilepsy. Pharmacogenomics 2012; 13: 185-190.
-
(2012)
Pharmacogenomics
, vol.13
, pp. 185-190
-
-
Hilger, E.1
Reinthaler, E.M.2
Stogmann, E.3
Hotzy, C.4
Pataraia, E.5
Baumgartner, C.6
|