Chemokine Co-Receptor CCR5/CXCR4-Dependent Modulation of Kv2.1 Channel Confers Acute Neuroprotection to HIV-1 Glycoprotein gp120 Exposure

PLoS ONE

Volumn 8, Issue 9, 2013, Pages

  Shepherd, Andrew J ^a   Loo, Lipin ^a   Mohapatra, Durga P ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCINEURIN; CALCIUM ION; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CXCR4; GLYCOPROTEIN GP 120; POTASSIUM CHANNEL KV2.1; UNCLASSIFIED DRUG; VOLTAGE GATED POTASSIUM CHANNEL;

ANIMAL CELL; ARTICLE; BRAIN INFECTION; CALCIUM CELL LEVEL; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOKINE RESPONSE; EMBRYO; EXPOSURE; FEMALE; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; IMMUNOCYTOCHEMISTRY; INTRACELLULAR SIGNALING; MALE; NERVE CELL CULTURE; NERVE CELL EXCITABILITY; NERVE CELL NECROSIS; NEUROMODULATION; NEUROPROTECTION; NONHUMAN; PHARMACOLOGICAL BLOCKING; PROTEIN DEPHOSPHORYLATION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RAT; UPREGULATION;

ANIMALS; APOPTOSIS; CALCINEURIN; CALCIUM; FEMALE; HIPPOCAMPUS; HIV ENVELOPE PROTEIN GP120; HIV-1; INTRACELLULAR SPACE; MALE; NEURONS; PHOSPHORYLATION; PROTEIN TRANSPORT; RATS; RECEPTORS, CCR5; RECEPTORS, CXCR4; SHAB POTASSIUM CHANNELS; SIGNAL TRANSDUCTION;

EID: 84884585630     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0076698     Document Type: Article

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