Depletion of the Adaptor Protein NCK Increases UV-Induced p53 Phosphorylation and Promotes Apoptosis

PLoS ONE

Volumn 8, Issue 9, 2013, Pages

  Errington, Timothy M ^a   Macara, Ian G ^b  

^a UNIVERSITY OF VIRGINIA   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATR PROTEIN; CASPASE 3; DNA; ISOPROTEIN; NCK PROTEIN; NCK1 PROTEIN; NCK2 PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN P53; SUPPRESSOR OF CYTOKINE SIGNALING; SUPPRESSOR OF CYTOKINE SIGNALING 7; TYROSINE KINASE RECEPTOR; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL NUCLEUS; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOSKELETON; DNA DAMAGE; HUMAN; HUMAN CELL; MOLECULAR EVOLUTION; PROTEIN CLEAVAGE; PROTEIN DEPLETION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN TRANSPORT; RADIATION EXPOSURE; SIGNAL TRANSDUCTION; ULTRAVIOLET RADIATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; APOPTOSIS; CASPASE 3; FLUORESCENT ANTIBODY TECHNIQUE; HEK293 CELLS; HELA CELLS; HUMANS; IMMUNOBLOTTING; IMMUNOPRECIPITATION; NUCLEAR PROTEINS; ONCOGENE PROTEINS; PHOSPHORYLATION; POLY(ADP-RIBOSE) POLYMERASES; PROTEIN ISOFORMS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS; TUMOR SUPPRESSOR PROTEIN P53; ULTRAVIOLET RAYS;

EID: 84884524958     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0076204     Document Type: Article

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