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Volumn 65, Issue , 2013, Pages 1069-1077

Gamma-tocopherol attenuates moderate but not severe colitis and suppresses moderate colitis-promoted colon tumorigenesis in mice

Author keywords

Carboxychromanol; Colitis; Colon cancer; Inflammation; Tocopherol; Vitamin E

Indexed keywords

AZOXYMETHANE; DEXTRAN SULFATE; GAMMA TOCOPHEROL; ANTINEOPLASTIC AGENT; ANTIOXIDANT;

EID: 84884505029     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2013.08.187     Document Type: Article
Times cited : (43)

References (45)
  • 1
    • 0036637235 scopus 로고    scopus 로고
    • Chemoprevention: An essential approach to controlling cancer
    • M.B. Sporn, and N. Suh Chemoprevention: an essential approach to controlling cancer Nat. Rev. Cancer 2 2002 537 543 (Pubitemid 37328935)
    • (2002) Nature Reviews Cancer , vol.2 , Issue.7 , pp. 537-543
    • Sporn, M.B.1    Suh, N.2
  • 3
    • 0037180757 scopus 로고    scopus 로고
    • Inflammation and cancer
    • DOI 10.1038/nature01322
    • L.M. Coussens, and Z. Werb Inflammation and cancer Nature 420 2002 860 867 (Pubitemid 36019639)
    • (2002) Nature , vol.420 , Issue.6917 , pp. 860-867
    • Coussens, L.M.1    Werb, Z.2
  • 4
    • 80052014052 scopus 로고    scopus 로고
    • Inflammation meets cancer, with NF-kappaB as the matchmaker
    • Y. Ben-Neriah, and M. Karin Inflammation meets cancer, with NF-kappaB as the matchmaker Nat. Immunol. 12 2011 715 723
    • (2011) Nat. Immunol. , vol.12 , pp. 715-723
    • Ben-Neriah, Y.1    Karin, M.2
  • 5
    • 77950346282 scopus 로고    scopus 로고
    • Immunity, inflammation, and cancer
    • S.I. Grivennikov, F.R. Greten, and M. Karin Immunity, inflammation, and cancer Cell 140 2010 883 899
    • (2010) Cell , vol.140 , pp. 883-899
    • Grivennikov, S.I.1    Greten, F.R.2    Karin, M.3
  • 7
    • 0036791124 scopus 로고    scopus 로고
    • Identities and differences in the metabolism of tocotrienols and tocopherols in HepG2 cells
    • M. Birringer, P. Pfluger, D. Kluth, N. Landes, and R. Brigelius-Flohe Identities and differences in the metabolism of tocotrienols and tocopherols in HepG2 cells J. Nutr. 132 2002 3113 3118
    • (2002) J. Nutr. , vol.132 , pp. 3113-3118
    • Birringer, M.1    Pfluger, P.2    Kluth, D.3    Landes, N.4    Brigelius-Flohe, R.5
  • 8
    • 0033037413 scopus 로고    scopus 로고
    • Vitamin E: Function and metabolism
    • R. Brigelius-Flohe, and M.G. Traber Vitamin E: function and metabolism FASEB J 13 1999 1145 1155 (Pubitemid 29300361)
    • (1999) FASEB Journal , vol.13 , Issue.10 , pp. 1145-1155
    • Brigelius-Flohe, R.1    Traber, M.G.2
  • 9
    • 34248183943 scopus 로고    scopus 로고
    • Identification and quantitation of novel vitamin E metabolites, sulfated long-chain carboxychromanols, in human A549 cells and in rats
    • DOI 10.1194/jlr.D700001-JLR200
    • Q. Jiang, H. Freiser, K.V. Wood, and X. Yin Identification and quantitation of novel vitamin E metabolites, sulfated long-chain carboxychromanols, in human A549 cells and in rats J. Lipid Res. 48 2007 1221 1230 (Pubitemid 46708689)
    • (2007) Journal of Lipid Research , vol.48 , Issue.5 , pp. 1221-1230
    • Jiang, Q.1    Freiser, H.2    Wood, K.V.3    Yin, X.4
  • 10
    • 0037067711 scopus 로고    scopus 로고
    • Cytochrome P450 ω-hydroxylase pathway of tocopherol catabolism: Novel mechanism of regulation of vitamin E status
    • DOI 10.1074/jbc.M201466200
    • T.J. Sontag, and R.S. Parker Cytochrome P450 omega-hydroxylase pathway of tocopherol catabolism. Novel mechanism of regulation of vitamin E status J. Biol. Chem. 277 2002 25290 25296 (Pubitemid 34951838)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.28 , pp. 25290-25296
    • Sontag, T.J.1    Parker, R.S.2
  • 13
    • 0034633629 scopus 로고    scopus 로고
    • Gamma-tocopherol and its major metabolite, in contrast to alpha-tocopherol, inhibit cyclooxygenase activity in macrophages and epithelial cells
    • Q. Jiang, I. Elson-Schwab, C. Courtemanche, and B.N. Ames Gamma-tocopherol and its major metabolite, in contrast to alpha-tocopherol, inhibit cyclooxygenase activity in macrophages and epithelial cells Proc. Natl. Acad. Sci. USA 97 2000 11494 11499
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 11494-11499
    • Jiang, Q.1    Elson-Schwab, I.2    Courtemanche, C.3    Ames, B.N.4
  • 14
    • 58149488676 scopus 로고    scopus 로고
    • Long-chain carboxychromanols, metabolites of vitamin E, are potent inhibitors of cyclooxygenases
    • Q. Jiang, X. Yin, M.A. Lill, M.L. Danielson, H. Freiser, and J. Huang Long-chain carboxychromanols, metabolites of vitamin E, are potent inhibitors of cyclooxygenases Proc. Natl. Acad. Sci. USA 105 2008 20464 20469
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 20464-20469
    • Jiang, Q.1    Yin, X.2    Lill, M.A.3    Danielson, M.L.4    Freiser, H.5    Huang, J.6
  • 16
    • 35448941843 scopus 로고    scopus 로고
    • Anti-inflammatory properties of alpha- and gamma-tocopherol
    • E. Reiter, Q. Jiang, and S. Christen Anti-inflammatory properties of alpha- and gamma-tocopherol Mol. Aspects Med. 28 2007 668 691
    • (2007) Mol. Aspects Med. , vol.28 , pp. 668-691
    • Reiter, E.1    Jiang, Q.2    Christen, S.3
  • 17
    • 79251568317 scopus 로고    scopus 로고
    • Natural forms of vitamin e and 13′-carboxychromanol, a long-chain vitamin e metabolite, inhibit leukotriene generation from stimulated neutrophils by blocking calcium influx and suppressing 5-lipoxygenase activity, respectively
    • Z. Jiang, X. Yin, and Q. Jiang Natural forms of vitamin E and 13′-carboxychromanol, a long-chain vitamin E metabolite, inhibit leukotriene generation from stimulated neutrophils by blocking calcium influx and suppressing 5-lipoxygenase activity, respectively J. Immunol 186 2011 1173 1179
    • (2011) J. Immunol , vol.186 , pp. 1173-1179
    • Jiang, Z.1    Yin, X.2    Jiang, Q.3
  • 18
    • 0038375011 scopus 로고    scopus 로고
    • γ-tocopherol, but not α-tocopherol, decreases proinflammatory eicosanoids and inflammation damage in rats
    • DOI 10.1096/fj.02-0877com
    • Q. Jiang, and B.N. Ames Gamma-tocopherol, but not alpha-tocopherol, decreases proinflammatory eicosanoids and inflammation damage in rats FASEB J 17 2003 816 822 (Pubitemid 36538656)
    • (2003) FASEB Journal , vol.17 , Issue.8 , pp. 816-822
    • Jiang, Q.1    Ames, B.N.2
  • 19
    • 0036889813 scopus 로고    scopus 로고
    • γ-tocopherol supplementation inhibits protein nitration and ascorbate oxidation in rats with inflammation
    • DOI 10.1016/S0891-5849(02)01091-2, PII S0891584902010912
    • Q. Jiang, J. Lykkesfeldt, M.K. Shigenaga, E.T. Shigeno, S. Christen, and B.N. Ames Gamma-tocopherol supplementation inhibits protein nitration and ascorbate oxidation in rats with inflammation Free Radic. Biol. Med. 33 2002 1534 1542 (Pubitemid 35351597)
    • (2002) Free Radical Biology and Medicine , vol.33 , Issue.11 , pp. 1534-1542
    • Jiang, Q.1    Lykkesfeldt, J.2    Shigenaga, M.K.3    Shigeno, E.T.4    Christen, S.5    Ames, B.N.6
  • 23
    • 0036884117 scopus 로고    scopus 로고
    • Gamma-tocopherol inhibits human cancer cell cycle progression and cell proliferation by down-regulation of cyclins
    • R. Gysin, A. Azzi, and T. Visarius Gamma-tocopherol inhibits human cancer cell cycle progression and cell proliferation by down-regulation of cyclins FASEB J 16 2002 1952 1954
    • (2002) FASEB J , vol.16 , pp. 1952-1954
    • Gysin, R.1    Azzi, A.2    Visarius, T.3
  • 25
    • 82255191935 scopus 로고    scopus 로고
    • Gamma-tocotrienol induces apoptosis and autophagy in prostate cancer cells by increasing intracellular dihydrosphingosine and dihydroceramide
    • Q. Jiang, X. Rao, C.Y. Kim, H. Freiser, Q. Zhang, Z. Jiang, and G. Li Gamma-tocotrienol induces apoptosis and autophagy in prostate cancer cells by increasing intracellular dihydrosphingosine and dihydroceramide Int. J. Cancer 130 2012 685 693
    • (2012) Int. J. Cancer , vol.130 , pp. 685-693
    • Jiang, Q.1    Rao, X.2    Kim, C.Y.3    Freiser, H.4    Zhang, Q.5    Jiang, Z.6    Li, G.7
  • 28
    • 63249095069 scopus 로고    scopus 로고
    • A gamma-tocopherol-rich mixture of tocopherols inhibits colon inflammation and carcinogenesis in azoxymethane and dextran sulfate sodium-treated mice
    • J. Ju, X. Hao, M.J. Lee, J.D. Lambert, G. Lu, H. Xiao, H.L. Newmark, and C.S. Yang A gamma-tocopherol-rich mixture of tocopherols inhibits colon inflammation and carcinogenesis in azoxymethane and dextran sulfate sodium-treated mice Cancer Prev. Res. (Phila.) 2 2009 143 152
    • (2009) Cancer Prev. Res. (Phila.) , vol.2 , pp. 143-152
    • Ju, J.1    Hao, X.2    Lee, M.J.3    Lambert, J.D.4    Lu, G.5    Xiao, H.6    Newmark, H.L.7    Yang, C.S.8
  • 29
    • 33846616837 scopus 로고    scopus 로고
    • Mixed tocopherols inhibit azoxymethane-induced aberrant crypt foci in rats
    • DOI 10.1207/s15327914nc5601-11
    • H.L. Newmark, M.T. Huang, and B.S. Reddy Mixed tocopherols inhibit azoxymethane-induced aberrant crypt foci in rats Nutr. Cancer 56 2006 82 85 (Pubitemid 46173417)
    • (2006) Nutrition and Cancer , vol.56 , Issue.1 , pp. 82-85
    • Newmark, H.L.1    Huang, M.-T.2    Reddy, B.S.3
  • 30
    • 84864834733 scopus 로고    scopus 로고
    • Delta- and gamma-tocopherols, but not alpha-tocopherol, inhibit colon carcinogenesis in azoxymethane-treated F344 rats
    • F. Guan, G. Li, A.B. Liu, M.J. Lee, Z. Yang, Y.K. Chen, Y. Lin, W. Shih, and C.S. Yang Delta- and gamma-tocopherols, but not alpha-tocopherol, inhibit colon carcinogenesis in azoxymethane-treated F344 rats Cancer Prev. Res. (Phila.) 5 2012 644 654
    • (2012) Cancer Prev. Res. (Phila.) , vol.5 , pp. 644-654
    • Guan, F.1    Li, G.2    Liu, A.B.3    Lee, M.J.4    Yang, Z.5    Chen, Y.K.6    Lin, Y.7    Shih, W.8    Yang, C.S.9
  • 32
    • 71749114450 scopus 로고    scopus 로고
    • A combination of aspirin and gamma-tocopherol is superior to that of aspirin and alpha-tocopherol in anti-inflammatory action and attenuation of aspirin-induced adverse effects
    • Q. Jiang, M. Moreland, B.N. Ames, and X. Yin A combination of aspirin and gamma-tocopherol is superior to that of aspirin and alpha-tocopherol in anti-inflammatory action and attenuation of aspirin-induced adverse effects J. Nutr. Biochem 20 2009 894 900
    • (2009) J. Nutr. Biochem , vol.20 , pp. 894-900
    • Jiang, Q.1    Moreland, M.2    Ames, B.N.3    Yin, X.4
  • 33
    • 29744461120 scopus 로고    scopus 로고
    • Strain differences in the susceptibility to azoxymethane and dextran sodium sulfate-induced colon carcinogenesis in mice
    • DOI 10.1093/carcin/bgi205
    • R. Suzuki, H. Kohno, S. Sugie, H. Nakagama, and T. Tanaka Strain differences in the susceptibility to azoxymethane and dextran sodium sulfate-induced colon carcinogenesis in mice Carcinogenesis 27 2006 162 169 (Pubitemid 43025257)
    • (2006) Carcinogenesis , vol.27 , Issue.1 , pp. 162-169
    • Suzuki, R.1    Kohno, H.2    Sugie, S.3    Nakagama, H.4    Tanaka, T.5
  • 34
    • 4043088499 scopus 로고    scopus 로고
    • IKKβ links inflammation and tumorigenesis in a mouse model of colitis-associated cancer
    • DOI 10.1016/j.cell.2004.07.013, PII S0092867404006713
    • F.R. Greten, L. Eckmann, T.F. Greten, J.M. Park, Z.W. Li, L.J. Egan, M.F. Kagnoff, and M. Karin IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer Cell 118 2004 285 296 (Pubitemid 39061110)
    • (2004) Cell , vol.118 , Issue.3 , pp. 285-296
    • Greten, F.R.1    Eckmann, L.2    Greten, T.F.3    Park, J.M.4    Li, Z.-W.5    Egan, L.J.6    Kagnoff, M.F.7    Karin, M.8
  • 36
    • 34548162712 scopus 로고    scopus 로고
    • An inducible mouse model of colon carcinogenesis for the analysis of sporadic and inflammation-driven tumor progression
    • DOI 10.1038/nprot.2007.279, PII NPROT.2007.279
    • C. Neufert, C. Becker, and M.F. Neurath An inducible mouse model of colon carcinogenesis for the analysis of sporadic and inflammation-driven tumor progression Nat. Protoc 2 2007 1998 2004 (Pubitemid 47308138)
    • (2007) Nature Protocols , vol.2 , Issue.8 , pp. 1998-2004
    • Neufert, C.1    Becker, C.2    Neurath, M.F.3
  • 37
    • 79751489596 scopus 로고    scopus 로고
    • Molecular genetics of colorectal cancer
    • E.R. Fearon Molecular genetics of colorectal cancer Annu. Rev. Pathol 6 2011 479 507
    • (2011) Annu. Rev. Pathol , vol.6 , pp. 479-507
    • Fearon, E.R.1
  • 39
    • 0025312728 scopus 로고
    • A genetic model for colorectal tumorigenesis
    • E.R. Fearon, and B. Vogelstein A genetic model for colorectal tumorigenesis Cell 61 1990 759 767
    • (1990) Cell , vol.61 , pp. 759-767
    • Fearon, E.R.1    Vogelstein, B.2
  • 40
    • 1642372407 scopus 로고    scopus 로고
    • Incidence and recurrence rates of colorectal adenomas estimated by annually repeated colonoscopies on asymptomatic Japanese
    • DOI 10.1136/gut.2003.026112
    • Y. Yamaji, T. Mitsushima, H. Ikuma, H. Watabe, M. Okamoto, T. Kawabe, R. Wada, H. Doi, and M. Omata Incidence and recurrence rates of colorectal adenomas estimated by annually repeated colonoscopies on asymptomatic Japanese Gut 53 2004 568 572 (Pubitemid 38372983)
    • (2004) Gut , vol.53 , Issue.4 , pp. 568-572
    • Yamaji, Y.1    Mitsushima, T.2    Ikuma, H.3    Watabe, H.4    Okamoto, M.5    Kawabe, T.6    Wada, R.7    Doi, H.8    Omata, M.9
  • 41
    • 65449180675 scopus 로고    scopus 로고
    • Colorectal carcinogenesis: Review of human and experimental animal studies
    • T. Tanaka Colorectal carcinogenesis: review of human and experimental animal studies J. Carcinogenesis 8 2009 5
    • (2009) J. Carcinogenesis , vol.8 , pp. 5
    • Tanaka, T.1
  • 42
    • 84862783272 scopus 로고    scopus 로고
    • The antioxidant and anti-inflammatory activities of tocopherols are independent of Nrf2 in mice
    • G. Li, M.J. Lee, A.B. Liu, Z. Yang, Y. Lin, W.J. Shih, and C.S. Yang The antioxidant and anti-inflammatory activities of tocopherols are independent of Nrf2 in mice Free Radic. Biol. Med. 52 2012 1151 1158
    • (2012) Free Radic. Biol. Med. , vol.52 , pp. 1151-1158
    • Li, G.1    Lee, M.J.2    Liu, A.B.3    Yang, Z.4    Lin, Y.5    Shih, W.J.6    Yang, C.S.7
  • 43
    • 67650667753 scopus 로고    scopus 로고
    • Temporal and spatial analysis of clinical and molecular parameters in dextran sodium sulfate induced colitis
    • Y. Yan, V. Kolachala, G. Dalmasso, H. Nguyen, H. Laroui, S.V. Sitaraman, and D. Merlin Temporal and spatial analysis of clinical and molecular parameters in dextran sodium sulfate induced colitis PloS One 4 2009 e6073
    • (2009) PloS One , vol.4 , pp. 6073
    • Yan, Y.1    Kolachala, V.2    Dalmasso, G.3    Nguyen, H.4    Laroui, H.5    Sitaraman, S.V.6    Merlin, D.7
  • 44
    • 84869056221 scopus 로고    scopus 로고
    • Disruption of P450-mediated vitamin e hydroxylase activities alters vitamin e status in tocopherol supplemented mice and reveals extra-hepatic vitamin e metabolism
    • S.A. Bardowell, X. Ding, and R.S. Parker Disruption of P450-mediated vitamin E hydroxylase activities alters vitamin E status in tocopherol supplemented mice and reveals extra-hepatic vitamin E metabolism J. Lipid Res 53 2012 2667 2676
    • (2012) J. Lipid Res , vol.53 , pp. 2667-2676
    • Bardowell, S.A.1    Ding, X.2    Parker, R.S.3
  • 45
    • 84864386099 scopus 로고    scopus 로고
    • Disruption of mouse cytochrome p450 4f14 (Cyp4f14 gene) causes severe perturbations in vitamin e metabolism
    • S.A. Bardowell, F. Duan, D. Manor, J.E. Swanson, and R.S. Parker Disruption of mouse cytochrome p450 4f14 (Cyp4f14 gene) causes severe perturbations in vitamin E metabolism J. Biol. Chem. 287 2012 26077 26086
    • (2012) J. Biol. Chem. , vol.287 , pp. 26077-26086
    • Bardowell, S.A.1    Duan, F.2    Manor, D.3    Swanson, J.E.4    Parker, R.S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.