Microsatellite instability in pediatric high grade glioma is associated with genomic profile and differential target gene inactivation

PLoS ONE

Volumn 6, Issue 5, 2011, Pages

  Viana Pereira, Marta ^a,b   Lee, Alicia ^b   Popov, Sergey ^b,c   Bax, Dorine A ^b   Al Sarraj, Safa ^d   Bridges, Leslie R ^e   StávaleJoã, João N ^f   Hargrave, Darren ^c   Jones, Chris ^b,c   Reis, Rui M ^a,g  

^a UNIVERSITY OF MINHO   (Portugal)

^b INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^c ROYAL MARSDEN HOSPITAL   (United Kingdom)

^d KING'S COLLEGE LONDON   (United Kingdom)

^e ST GEORGE S HOSPITAL   (United Kingdom)

^f FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^g Barretos Cancer Hospital   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; INTERMEDIN; MISMATCH REPAIR PROTEIN PMS2; PROTEIN MLH1; PROTEIN MSH6; DNA BINDING PROTEIN; MRE11A PROTEIN, HUMAN;

ADOLESCENT; ADULT; AGE DISTRIBUTION; AGED; ARTICLE; CANCER GRADING; CHILD; CONTROLLED STUDY; DNA METHYLATION; DNA REPAIR; DNA STRAND BREAKAGE; DNAPK GENE; DOWN REGULATION; GENE ACTIVATION; GENE DOSAGE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE MUTATION; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GLIOMA; HUMAN; HUMAN CELL; HUMAN TISSUE; INHERITANCE; MICROSATELLITE INSTABILITY; MISMATCH REPAIR; MLH1 GENE; MRE11 GENE; MSH2 GENE; MSH6 GENE; ONCOGENE; PMS2 GENE; PRESCHOOL CHILD; PROMOTER REGION; SCHOOL CHILD; DOUBLE STRANDED DNA BREAK; FEMALE; FRAMESHIFT MUTATION; GENE SILENCING; GENETICS; HUMAN GENOME; INFANT; MALE; MIDDLE AGED; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; TUMOR GENE;

ADOLESCENT; ADULT; AGED; BASE SEQUENCE; CHILD; DNA BREAKS, DOUBLE-STRANDED; DNA MISMATCH REPAIR; DNA-BINDING PROTEINS; FEMALE; FRAMESHIFT MUTATION; GENE SILENCING; GENES, NEOPLASM; GENOME, HUMAN; GLIOMA; HUMANS; INFANT; MALE; MICROSATELLITE INSTABILITY; MIDDLE AGED; MOLECULAR SEQUENCE DATA; POLYMORPHISM, GENETIC; YOUNG ADULT;

EID: 79957555791     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0020588     Document Type: Article

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