-
1
-
-
0027381336
-
Lymphocyte subsets and natural killer cell activity in healthy old people and centenarians
-
Lymphocyte subsets and natural killer cell activity in healthy old people and centenarians. Sansoni P, Cossarizza A, Brianti V, Fagnoni F, Snelli G, Monti D, Marcato A, Passeri G, Ortolani C, Forti E, et al. Blood 1993 82 9 2767 2773 8219229 (Pubitemid 23318083)
-
(1993)
Blood
, vol.82
, Issue.9
, pp. 2767-2773
-
-
Sansoni, P.1
Cossarizza, A.2
Brianti, V.3
Fagnoni, F.4
Snelli, G.5
Monti, D.6
Marcato, A.7
Passeri, G.8
Ortolani, C.9
Forti, E.10
Fagiolo, U.11
Passeri, M.12
Franceschi, C.13
-
2
-
-
0000075523
-
The behavior in successive nuclear divisions of a chromosome broken at meiosis
-
10.1073/pnas.25.8.405 16577924
-
The behavior in successive nuclear divisions of a chromosome broken at meiosis. McClintock B, Proc Natl Acad Sci USA 1939 25 8 405 416 10.1073/pnas.25.8.405 16577924
-
(1939)
Proc Natl Acad Sci USA
, vol.25
, Issue.8
, pp. 405-416
-
-
McClintock, B.1
-
3
-
-
0035929353
-
Switching and signaling at the telomere
-
DOI 10.1016/S0092-8674(01)00492-5
-
Switching and signaling at the telomere. Blackburn EH, Cell 2001 106 6 661 673 10.1016/S0092-8674(01)00492-5 11572773 (Pubitemid 32900658)
-
(2001)
Cell
, vol.106
, Issue.6
, pp. 661-673
-
-
Blackburn, E.H.1
-
4
-
-
23844540299
-
Molecular biology: Effects of telomerase and telomere length on epidermal stem cell behavior
-
DOI 10.1126/science.1115025
-
Effects of telomerase and telomere length on epidermal stem cell behavior. Flores I, Cayuela ML, Blasco MA, Science 2005 309 5738 1253 1256 10.1126/science.1115025 16037417 (Pubitemid 41170921)
-
(2005)
Science
, vol.309
, Issue.5738
, pp. 1253-1256
-
-
Flores, I.1
Cayuela, M.L.2
Blasco, M.A.3
-
5
-
-
0026460896
-
Telomere length predicts replicative capacity of human fibroblasts
-
10.1073/pnas.89.21.10114 1438199
-
Telomere length predicts replicative capacity of human fibroblasts. Allsopp RC, Vaziri H, Patterson C, Goldstein S, Younglai EV, Futcher AB, Greider CW, Harley CB, Proc Natl Acad Sci USA 1992 89 21 10114 10118 10.1073/pnas.89.21.10114 1438199
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, Issue.21
, pp. 10114-10118
-
-
Allsopp, R.C.1
Vaziri, H.2
Patterson, C.3
Goldstein, S.4
Younglai, E.V.5
Futcher, A.B.6
Greider, C.W.7
Harley, C.B.8
-
6
-
-
0037320653
-
Role of oxidative stress in telomere shortening in cultured fibroblasts from normal individuals and patients with ataxia-telengiectasia
-
DOI 10.1093/hmg/ddg023
-
Role of oxidative stress in telomere shortening in cultured fibroblasts from normal individuals and patients with ataxia-telangiectasia. Tchirkov A, Lansdorp PM, Hum Mol Genet 2003 12 3 227 232 10.1093/hmg/ddg023 12554677 (Pubitemid 36204420)
-
(2003)
Human Molecular Genetics
, vol.12
, Issue.3
, pp. 227-232
-
-
Tchirkov, A.1
Lansdorp, P.M.2
-
7
-
-
0344622606
-
The serial cultivation of human diploid cell strains
-
10.1016/0014-4827(61)90192-6 13905658
-
The serial cultivation of human diploid cell strains. Hayflick L, Moorhead PS, Exp Cell Res 1961 25 585 621 10.1016/0014-4827(61)90192-6 13905658
-
(1961)
Exp Cell Res
, vol.25
, pp. 585-621
-
-
Hayflick, L.1
Moorhead, P.S.2
-
8
-
-
77953161582
-
Telomere loss as a mechanism for chromosome instability in human cancer
-
10.1158/0008-5472.CAN-09-4357 20484032
-
Telomere loss as a mechanism for chromosome instability in human cancer. Murnane JP, Cancer Res 2010 70 11 4255 4259 10.1158/0008-5472.CAN-09-4357 20484032
-
(2010)
Cancer Res
, vol.70
, Issue.11
, pp. 4255-4259
-
-
Murnane, J.P.1
-
9
-
-
0037178761
-
Connecting chromosomes, crisis, and cancer
-
DOI 10.1126/science.297.5581.565
-
Connecting chromosomes, crisis, and cancer. Maser RS, DePinho RA, Science 2002 297 5581 565 569 10.1126/science.297.5581.565 12142527 (Pubitemid 34815334)
-
(2002)
Science
, vol.297
, Issue.5581
, pp. 565-569
-
-
Maser, R.S.1
DePinho, R.A.2
-
10
-
-
77950265945
-
Linking functional decline of telomeres, mitochondria and stem cells during ageing
-
10.1038/nature08982 20336134
-
Linking functional decline of telomeres, mitochondria and stem cells during ageing. Sahin E, Depinho RA, Nature 2010 464 7288 520 528 10.1038/nature08982 20336134
-
(2010)
Nature
, vol.464
, Issue.7288
, pp. 520-528
-
-
Sahin, E.1
Depinho, R.A.2
-
11
-
-
78650980433
-
Aging by telomere loss can be reversed
-
10.1016/j.stem.2010.12.013 21211774
-
Aging by telomere loss can be reversed. Bernardes de Jesus B, Blasco MA, Cell Stem Cell 2011 8 1 3 4 10.1016/j.stem.2010.12.013 21211774
-
(2011)
Cell Stem Cell
, vol.8
, Issue.1
, pp. 3-4
-
-
Bernardes De Jesus, B.1
Blasco, M.A.2
-
12
-
-
78650990326
-
Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice
-
10.1038/nature09603 21113150
-
Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice. Jaskelioff M, Muller FL, Paik JH, Thomas E, Jiang S, Adams AC, Sahin E, Kost-Alimova M, Protopopov A, Cadinanos J, et al. Nature 2011 469 7328 102 106 10.1038/nature09603 21113150
-
(2011)
Nature
, vol.469
, Issue.7328
, pp. 102-106
-
-
Jaskelioff, M.1
Muller, F.L.2
Paik, J.H.3
Thomas, E.4
Jiang, S.5
Adams, A.C.6
Sahin, E.7
Kost-Alimova, M.8
Protopopov, A.9
Cadinanos, J.10
-
13
-
-
0032440891
-
Dissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization
-
DOI 10.1073/pnas.95.25.14723
-
Dissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization. Counter CM, Hahn WC, Wei W, Caddle SD, Beijersbergen RL, Lansdorp PM, Sedivy JM, Weinberg RA, Proc Natl Acad Sci USA 1998 95 25 14723 14728 10.1073/pnas.95.25.14723 9843956 (Pubitemid 29003697)
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.25
, pp. 14723-14728
-
-
Counter, C.M.1
Hahn, W.C.2
Wei, W.3
Caddle, S.D.4
Beijersbergen, R.L.5
Lansdorp, P.M.6
Sedivy, J.M.7
Weinberg, R.A.8
-
14
-
-
0031962972
-
Changes of telomere length in children after hematopoietic stem cell transplantation
-
Changes of telomere length in children after hematopoietic stem cell transplantation. Akiyama M, Hoshi Y, Sakurai S, Yamada H, Yamada O, Mizoguchi H, Bone Marrow Transpl 1998 21 2 167 171 10.1038/sj.bmt.1701060 (Pubitemid 28044010)
-
(1998)
Bone Marrow Transplantation
, vol.21
, Issue.2
, pp. 167-171
-
-
Akiyama, M.1
Hoshi, Y.2
Sakurai, S.3
Yamada, H.4
Yamada, O.5
Mizoguchi, H.6
-
15
-
-
0033541401
-
Telomere length in fibroblasts and blood cells from healthy centenarians
-
DOI 10.1006/excr.1999.4398
-
Telomere length in fibroblasts and blood cells from healthy centenarians. Mondello C, Petropoulou C, Monti D, Gonos ES, Franceschi C, Nuzzo F, Exp Cell Res 1999 248 1 234 242 10.1006/excr.1999.4398 10094830 (Pubitemid 29393946)
-
(1999)
Experimental Cell Research
, vol.248
, Issue.1
, pp. 234-242
-
-
Mondello, C.1
Petropoulou, C.2
Monti, D.3
Gonos, E.S.4
Franceschi, C.5
Nuzzo, F.6
-
16
-
-
0029156035
-
Telomere shortening is associated with cell division in vitro and in vivo
-
10.1006/excr.1995.1306 7664836
-
Telomere shortening is associated with cell division in vitro and in vivo. Allsopp RC, Chang E, Kashefi-Aazam M, Rogaev EI, Piatyszek MA, Shay JW, Harley CB, Exp Cell Res 1995 220 1 194 200 10.1006/excr.1995.1306 7664836
-
(1995)
Exp Cell Res
, vol.220
, Issue.1
, pp. 194-200
-
-
Allsopp, R.C.1
Chang, E.2
Kashefi-Aazam, M.3
Rogaev, E.I.4
Piatyszek, M.A.5
Shay, J.W.6
Harley, C.B.7
-
17
-
-
2342419515
-
Telomere measurement by quantitative PCR
-
10.1093/nar/30.10.e47 12000852
-
Telomere measurement by quantitative PCR. Cawthon RM, Nucleic Acids Res 2002 30 10 47 10.1093/nar/30.10.e47 12000852
-
(2002)
Nucleic Acids Res
, vol.30
, Issue.10
, pp. 547
-
-
Cawthon, R.M.1
-
18
-
-
33747876876
-
Telomere Shortening and Mood Disorders: Preliminary Support for a Chronic Stress Model of Accelerated Aging
-
DOI 10.1016/j.biopsych.2006.02.004, PII S0006322306001363
-
Telomere shortening and mood disorders: preliminary support for a chronic stress model of accelerated aging. Simon NM, Smoller JW, McNamara KL, Maser RS, Zalta AK, Pollack MH, Nierenberg AA, Fava M, Wong KK, Biol Psychiatry 2006 60 5 432 435 10.1016/j.biopsych.2006.02.004 16581033 (Pubitemid 44292160)
-
(2006)
Biological Psychiatry
, vol.60
, Issue.5
, pp. 432-435
-
-
Simon, N.M.1
Smoller, J.W.2
McNamara, K.L.3
Maser, R.S.4
Zalta, A.K.5
Pollack, M.H.6
Nierenberg, A.A.7
Fava, M.8
Wong, K.-K.9
-
19
-
-
40349085766
-
The longest telomeres: A general signature of adult stem cell compartments
-
DOI 10.1101/gad.451008
-
The longest telomeres: a general signature of adult stem cell compartments. Flores I, Canela A, Vera E, Tejera A, Cotsarelis G, Blasco MA, Genes Dev 2008 22 5 654 667 10.1101/gad.451008 18283121 (Pubitemid 351342437)
-
(2008)
Genes and Development
, vol.22
, Issue.5
, pp. 654-667
-
-
Flores, I.1
Canela, A.2
Vera, E.3
Tejera, A.4
Cotsarelis, G.5
Blasco, M.A.6
-
20
-
-
71149086939
-
Short telomeres are sufficient to cause the degenerative defects associated with aging
-
10.1016/j.ajhg.2009.10.028 19944403
-
Short telomeres are sufficient to cause the degenerative defects associated with aging. Armanios M, Alder JK, Parry EM, Karim B, Strong MA, Greider CW, Am J Hum Genet 2009 85 6 823 832 10.1016/j.ajhg.2009.10.028 19944403
-
(2009)
Am J Hum Genet
, vol.85
, Issue.6
, pp. 823-832
-
-
Armanios, M.1
Alder, J.K.2
Parry, E.M.3
Karim, B.4
Strong, M.A.5
Greider, C.W.6
-
21
-
-
32944477215
-
Cell aging in relation to stress arousal and cardiovascular disease risk factors
-
DOI 10.1016/j.psyneuen.2005.08.011, PII S0306453005001897
-
Cell aging in relation to stress arousal and cardiovascular disease risk factors. Epel ES, Lin J, Wilhelm FH, Wolkowitz OM, Cawthon R, Adler NE, Dolbier C, Mendes WB, Blackburn EH, Psychoneuroendocrino 2006 31 3 277 287 10.1016/j.psyneuen.2005.08.011 (Pubitemid 43261645)
-
(2006)
Psychoneuroendocrinology
, vol.31
, Issue.3
, pp. 277-287
-
-
Epel, E.S.1
Lin, J.2
Wilhelm, F.H.3
Wolkowitz, O.M.4
Cawthon, R.5
Adler, N.E.6
Dolbier, C.7
Mendes, W.B.8
Blackburn, E.H.9
-
22
-
-
0027993344
-
Genetic determination of telomere size in humans: A twin study of three age groups
-
Genetic determination of telomere size in humans: a twin study of three age groups. Slagboom PE, Droog S, Boomsma DI, Am J Hum Genet 1994 55 5 876 882 7977349 (Pubitemid 24334278)
-
(1994)
American Journal of Human Genetics
, vol.55
, Issue.5
, pp. 876-882
-
-
Slagboom, P.E.1
Droog, S.2
Boomsma, D.I.3
-
24
-
-
0031922795
-
Telomeric length and telomerase activity vary with age in peripheral blood cells obtained from normal individuals
-
DOI 10.1007/s004390050711
-
Telomeric length and telomerase activity vary with age in peripheral blood cells obtained from normal individuals. Iwama H, Ohyashiki K, Ohyashiki JH, Hayashi S, Yahata N, Ando K, Toyama K, Hoshika A, Takasaki M, Mori M, et al. Hum Genet 1998 102 4 397 402 10.1007/s004390050711 9600234 (Pubitemid 28203979)
-
(1998)
Human Genetics
, vol.102
, Issue.4
, pp. 397-402
-
-
Iwama, H.1
Ohyashiki, K.2
Ohyashiki, J.H.3
Hayashi, S.4
Yahata, N.5
Ando, K.6
Toyama, K.7
Hoshika, A.8
Takasaki, M.9
Mori, M.10
Shay, J.W.11
-
25
-
-
0028850465
-
Human naive and memory T lymphocytes differ in telomeric length and replicative potential
-
10.1073/pnas.92.24.11091 7479943
-
Human naive and memory T lymphocytes differ in telomeric length and replicative potential. Weng NP, Levine BL, June CH, Hodes RJ, Proc Natl Acad Sci U S A 1995 92 24 11091 11094 10.1073/pnas.92.24.11091 7479943
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, Issue.24
, pp. 11091-11094
-
-
Weng, N.P.1
Levine, B.L.2
June, C.H.3
Hodes, R.J.4
-
26
-
-
0345643319
-
Telomere fluorescence measurements in granulocytes and T lymphocyte subsets point to a high turnover of hematopoietic stem cells and memory T cells in early childhood
-
DOI 10.1084/jem.190.2.157
-
Telomere fluorescence measurements in granulocytes and T lymphocyte subsets point to a high turnover of hematopoietic stem cells and memory T cells in early childhood. Rufer N, Brummendorf TH, Kolvraa S, Bischoff C, Christensen K, Wadsworth L, Schulzer M, Lansdorp PM, J Exp Med 1999 190 2 157 167 10.1084/jem.190.2.157 10432279 (Pubitemid 29354909)
-
(1999)
Journal of Experimental Medicine
, vol.190
, Issue.2
, pp. 157-167
-
-
Rufer, N.1
Brummendorf, T.H.2
Kolvraa, S.3
Bischoff, C.4
Christensen, K.5
Wadsworth, L.6
Schulzer, M.7
Lansdorp, P.M.8
-
27
-
-
0034846018
-
Telomere shortening and decline in replicative potential as a function of donor age in human adrenocortical cells
-
DOI 10.1016/S0047-6374(01)00280-9, PII S0047637401002809
-
Telomere shortening and decline in replicative potential as a function of donor age in human adrenocortical cells. Yang L, Suwa T, Wright WE, Shay JW, Hornsby PJ, Mech Ageing Dev 2001 122 15 1685 1694 10.1016/S0047-6374(01)00280-9 11557273 (Pubitemid 32835216)
-
(2001)
Mechanisms of Ageing and Development
, vol.122
, Issue.15
, pp. 1685-1694
-
-
Yang, L.1
Suwa, T.2
Wright, W.E.3
Shay, J.W.4
Hornsby, P.J.5
-
28
-
-
0034597794
-
Telomere states and cell fates
-
10.1038/35040500 11081503
-
Telomere states and cell fates. Blackburn EH, Nature 2000 408 6808 53 56 10.1038/35040500 11081503
-
(2000)
Nature
, vol.408
, Issue.6808
, pp. 53-56
-
-
Blackburn, E.H.1
-
29
-
-
0034616215
-
Subsenescent telomere lengths in fibroblasts immortalized by limiting amounts of telomerase
-
DOI 10.1074/jbc.275.14.10072
-
Subsenescent telomere lengths in fibroblasts immortalized by limiting amounts of telomerase. Ouellette MM, Liao M, Herbert BS, Johnson M, Holt SE, Liss HS, Shay JW, Wright WE, J Biol Chem 2000 275 14 10072 10076 10.1074/jbc.275.14.10072 10744686 (Pubitemid 30202057)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.14
, pp. 10072-10076
-
-
Ouellette, M.M.1
Liao, M.2
Herbert, B.-S.3
Johnson, M.4
Holt, S.E.5
Liss, H.S.6
Shay, J.W.7
Wright, W.E.8
-
30
-
-
0034456493
-
Cellular responses to telomere shortening: Cellular senescence as a tumor suppressor mechanism
-
12200870
-
Cellular responses to telomere shortening: cellular senescence as a tumor suppressor mechanism. Greider CW, Harvey Lect 2000 96 33 50 12200870
-
(2000)
Harvey Lect
, vol.96
, pp. 33-50
-
-
Greider, C.W.1
-
31
-
-
0035989630
-
The disparity between human cell senescence in vitro and lifelong replication in vivo
-
DOI 10.1038/nbt0702-675
-
The disparity between human cell senescence in vitro and lifelong replication in vivo. Rubin H, Nat Biotechnol 2002 20 7 675 681 10.1038/nbt0702-675 12089551 (Pubitemid 34734133)
-
(2002)
Nature Biotechnology
, vol.20
, Issue.7
, pp. 675-681
-
-
Rubin, H.1
-
32
-
-
70349859881
-
DNA damage, aging, and cancer
-
10.1056/NEJMra0804615 19812404
-
DNA damage, aging, and cancer. Hoeijmakers JH, N Engl J Med 2009 361 15 1475 1485 10.1056/NEJMra0804615 19812404
-
(2009)
N Engl J Med
, vol.361
, Issue.15
, pp. 1475-1485
-
-
Hoeijmakers, J.H.1
-
33
-
-
0037308404
-
Association between telomere length in blood and mortality in people aged 60 years or older
-
DOI 10.1016/S0140-6736(03)12384-7
-
Association between telomere length in blood and mortality in people aged 60 years or older. Cawthon RM, Smith KR, O'Brien E, Sivatchenko A, Kerber RA, Lancet 2003 361 9355 393 395 10.1016/S0140-6736(03)12384-7 12573379 (Pubitemid 36164975)
-
(2003)
Lancet
, vol.361
, Issue.9355
, pp. 393-395
-
-
Cawthon, R.M.1
Smith, K.R.2
O'Brien, E.3
Sivatchenko, A.4
Kerber, R.A.5
-
34
-
-
0034107028
-
Accelerated replicative senescence of the peripheral immune system induced by HIV infection
-
DOI 10.1097/00002030-200005050-00002
-
Accelerated replicative senescence of the peripheral immune system induced by HIV infection. Bestilny LJ, Gill MJ, Mody CH, Riabowol KT, Aids 2000 14 7 771 780 10.1097/00002030-200005050-00002 10839584 (Pubitemid 30303453)
-
(2000)
AIDS
, vol.14
, Issue.7
, pp. 771-780
-
-
Bestilny, L.J.1
Gill, M.J.2
Mody, C.H.3
Riabowol, K.T.4
-
35
-
-
0035867190
-
lo T Cells in Patients with Systemic Lupus Erythematosus
-
DOI 10.1006/clim.2001.5023
-
Telomere shortening and decreased replicative potential, contrasted by continued proliferation of telomerase-positive CD8+CD28(lo) T cells in patients with systemic lupus erythematosus. Honda M, Mengesha E, Albano S, Nichols WS, Wallace DJ, Metzger A, Klinenberg JR, Linker-Israeli M, Clin Immunol 2001 99 2 211 221 10.1006/clim.2001.5023 11318593 (Pubitemid 33763373)
-
(2001)
Clinical Immunology
, vol.99
, Issue.2
, pp. 211-221
-
-
Honda, M.1
Mengesha, E.2
Albano, S.3
Stephen Nichols, W.4
Wallace, D.J.5
Metzger, A.6
Klinenberg, J.R.7
Linker-Israeli, M.8
-
36
-
-
0034769105
-
-/- mice with short telomeres
-
DOI 10.1093/embo-reports/kve174
-
Restoration of telomerase activity rescues chromosomal instability and premature aging in Terc-/- mice with short telomeres. Samper E, Flores JM, Blasco MA, EMBO Rep 2001 2 9 800 807 10.1093/embo-reports/kve174 11520856 (Pubitemid 32982748)
-
(2001)
EMBO Reports
, vol.2
, Issue.9
, pp. 800-807
-
-
Samper, E.1
Flores, J.M.2
Blasco, M.A.3
-
37
-
-
0012950854
-
Lineage-specific telomere shortening and unaltered capacity for telomerase expression in human T and B lymphocytes with age
-
Lineage-specific telomere shortening and unaltered capacity for telomerase expression in human T and B lymphocytes with age. Son NH, Murray S, Yanovski J, Hodes RJ, Weng N, J Immunol 2000 165 3 1191 1196 10903716 (Pubitemid 30604544)
-
(2000)
Journal of Immunology
, vol.165
, Issue.3
, pp. 1191-1196
-
-
Son, N.H.1
Murray, S.2
Yanovski, J.3
Hodes, R.J.4
Weng, N.-P.5
-
38
-
-
34548153747
-
How stem cells age and why this makes us grow old
-
DOI 10.1038/nrm2241, PII NRM2241
-
How stem cells age and why this makes us grow old. Sharpless NE, DePinho RA, Nat Rev Mol Cell Biol 2007 8 9 703 713 10.1038/nrm2241 17717515 (Pubitemid 47312828)
-
(2007)
Nature Reviews Molecular Cell Biology
, vol.8
, Issue.9
, pp. 703-713
-
-
Sharpless, N.E.1
DePinho, R.A.2
|