IL-17 boosts proinflammatory outcome of antiviral response in human cells

Journal of Immunology

Volumn 187, Issue 10, 2011, Pages 5357-5362

  Ryzhakov, Grigory ^a   Lai, Cheryl Chuk Ke ^a   Blazek, Katrina ^a   To, Ken Win ^a   Hussell, Tracy ^b   Udalova, Irina ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

3 (4 METHYLPHENYLSULFONYL) 2 PROPENENITRILE; BETA INTERFERON; CXCL1 CHEMOKINE; DOUBLE STRANDED RNA; HELICASE; I KAPPA B KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON REGULATORY FACTOR 3; INTERLEUKIN 17; INTERLEUKIN 6; INTERLEUKIN 8; MDA 5 PROTEIN; MONOCYTE CHEMOTACTIC PROTEIN 2; POLYINOSINIC POLYCYTIDYLIC ACID; RETINOIC ACID INDUCIBLE PROTEIN I; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR ADAPTOR MOLECULE 1; TRANSCRIPTION FACTOR RELA; UNCLASSIFIED DRUG;

ARTICLE; CCL8 GENE; CONTROLLED STUDY; CXCL1 GENE; CYTOKINE RELEASE; GENE; GENE EXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; IKK GENE; IMMUNE RESPONSE; INFLAMMATION; INTERFERON REGULATORY FACTOR 3 GENE; INTERLEUKIN 6 GENE; INTERLEUKIN 8 GENE; MEDIATOR; NFKBIZ GENE; PRIORITY JOURNAL; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR RELA GENE; TRIF GENE; VIRUS CELL INTERACTION;

ANTIVIRAL AGENTS; CELLS, CULTURED; CYTOKINES; FIBROBLASTS; GENE EXPRESSION REGULATION; HUMANS; I-KAPPA B KINASE; INFLAMMATION MEDIATORS; INTERFERON REGULATORY FACTOR-3; INTERLEUKIN-17; POLY I-C; RESPIRATORY SYNCYTIAL VIRUSES; SIGNAL TRANSDUCTION; SKIN; TRANSCRIPTION FACTOR RELA; UP-REGULATION;

EID: 81455135812     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1100917     Document Type: Article

References (39)

1. Crowe, C. R., K. Chen, D. A. Pociask, J. F. Alcorn, C. Krivich, R. I. Enelow, T. M. Ross, J. L. Witztum, and J. K. Kolls. 2009. Critical role of IL-17RA in immunopathology of influenza infection. J. Immunol. 183: 5301-5310.
2. Patera, A. C., L. Pesnicak, J. Bertin, and J. I. Cohen. 2002. Interleukin 17 modulates the immune response to vaccinia virus infection. Virology 299: 56-63. (Pubitemid 35007511)
3. Stout-Delgado, H. W., W. Du, A. C. Shirali, C. J. Booth, and D. R. Goldstein. 2009. Aging promotes neutrophil-induced mortality by augmenting IL-17 production during viral infection. Cell Host Microbe 6: 446-456.
4. Hou, W., H. S. Kang, and B. S. Kim. 2009. Th17 cells enhance viral persistence and inhibit T cell cytotoxicity in a model of chronic virus infection. J. Exp. Med. 206: 313-328.
5. Wiehler, S., and D. Proud. 2007. Interleukin-17A modulates human airway epithelial responses to human rhinovirus infection. Am. J. Physiol. Lung Cell. Mol. Physiol. 293: L505-L515. (Pubitemid 47205032)
6. Yue, F. Y., A. Merchant, C. M. Kovacs, M. Loutfy, D. Persad, and M. A. Ostrowski. 2008. Virus-specific interleukin-17-producing CD4+ T cells are detectable in early human immunodeficiency virus type 1 infection. J. Virol. 82: 6767-6771. (Pubitemid 351875153)
7. Ge, J., K. Wang, Q. H. Meng, Z. X. Qi, F. L. Meng, and Y. C. Fan. 2010. Implication of Th17 and Th1 cells in patients with chronic active hepatitis B. J. Clin. Immunol. 30: 60-67.
8. Gaffen, S. L. 2009. Structure and signalling in the IL-17 receptor family. Nat. Rev. Immunol. 9: 556-567.
9. Hamada, H., Mde. L. Garcia-Hernandez, J. B. Reome, S. K. Misra, T. M. Strutt, K. K. McKinstry, A. M. Cooper, S. L. Swain, and R. W. Dutton. 2009. Tc17, a unique subset of CD8 T cells that can protect against lethal influenza challenge. J. Immunol. 182: 3469-3481.
10. Fossiez, F., O. Djossou, P. Chomarat, L. Flores-Romo, S. Ait-Yahia, C. Maat, J. J. Pin, P. Garrone, E. Garcia, S. Saeland, et al. 1996. T cell interleukin-17 induces stromal cells to produce proinflammatory and hematopoietic cytokines. J. Exp. Med. 183: 2593-2603. (Pubitemid 26193037)
11. Katz, Y., O. Nadiv, and Y. Beer. 2001. Interleukin-17 enhances tumor necrosis factor alpha-induced synthesis of interleukins 1,6, and 8 in skin and synovial fibroblasts: a possible role as a "fine-tuning cytokine" in inflammation processes. Arthritis Rheum. 44: 2176-2184. (Pubitemid 33644063)
12. Ge, D., and Z. You. 2008. Expression of interleukin-17RC protein in normal human tissues. Int Arch Med 1: 19.
13. Cortez, D. M., M. D. Feldman, S. Mummidi, A. J. Valente, B. Steffensen, M. Vincenti, J. L. Barnes, and B. Chandrasekar. 2007. IL-17 stimulates MMP-1 expression in primary human cardiac fibroblasts via p38 MAPK- and ERK1/2-dependent C/EBP-beta, NF-kappaB, and AP-1 activation. Am. J. Physiol. Heart Circ. Physiol. 293: H3356-H3365. (Pubitemid 350230876)
14. Rahman, M. S., J. Yang, L. Y. Shan, H. Unruh, X. Yang, A. J. Halayko, and A. S. Gounni. 2005. IL-17R activation of human airway smooth muscle cells induces CXCL-8 production via a transcriptional-dependent mechanism. Clin. Immunol. 115: 268-276. (Pubitemid 40712322)
15. Hartupee, J., C. Liu, M. Novotny, X. Li, and T. Hamilton. 2007. IL-17 enhances chemokine gene expression through mRNA stabilization. J. Immunol. 179: 4135-4141.
16. Hartupee, J., C. Liu, M. Novotny, D. Sun, X. Li, and T. A. Hamilton. 2009. IL-17 signaling for mRNA stabilization does not require TNF receptor-associated factor 6. J. Immunol. 182: 1660-1666.
17. Kawai, T., and S. Akira. 2008. Toll-like receptor and RIG-I-like receptor signaling. Ann. N. Y. Acad. Sci. 1143: 1-20.
18. Stowell, N. C., J. Seideman, H. A. Raymond, K. A. Smalley, R. J. Lamb, D. D. Egenolf, P. J. Bugelski, L. A. Murray, P. A. Marsters, R. A. Bunting, et al. 2009. Long-term activation of TLR3 by poly(I:C) induces inflammation and impairs lung function in mice. Respir. Res. 10: 43.
19. Choi, J. P., Y. S. Kim, Y. M. Tae, E. J. Choi, B. S. Hong, S. G. Jeon, Y. S. Gho, Z. Zhu, and Y. K. Kim. 2010. A viral PAMP double-stranded RNA induces allergen-specific Th17 cell response in the airways which is dependent on VEGF and IL-6. Allergy 65: 1322-1330.
20. Fitzgerald, K. A., S. M. McWhirter, K. L. Faia, D. C. Rowe, E. Latz, D. T. Golenbock, A. J. Coyle, S. M. Liao, and T. Maniatis. 2003. IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway. Nat. Immunol. 4: 491-496. (Pubitemid 36592443)
21. Kumar, A., J. Zhang, and F. S. Yu. 2006. Toll-like receptor 3 agonist poly(I:C)-induced antiviral response in human corneal epithelial cells. Immunology 117: 11-21.
22. Takeuchi, O., and S. Akira. 2008. MDA5/RIG-I and virus recognition. Curr. Opin. Immunol. 20: 17-22.
23. Yasuda, H., A. Leelahavanichkul, S. Tsunoda, J. W. Dear, Y. Takahashi, S. Ito, X. Hu, H. Zhou, K. Doi, R. Childs, et al. 2008. Chloroquine and inhibition of Toll-like receptor 9 protect from sepsis-induced acute kidney injury. Am. J. Physiol. Renal Physiol. 294: F1050-F1058.
24. Shalom-Barak, T., J. Quach, and M. Lotz. 1998. Interleukin-17-induced gene expression in articular chondrocytes is associated with activation of mitogen-activated protein kinases and NF-kappaB. J. Biol. Chem. 273: 27467-27473. (Pubitemid 28500465)
25. Schwandner, R., K. Yamaguchi, and Z. Cao. 2000. Requirement of tumor necrosis factor receptor-associated factor (TRAF)6 in interleukin 17 signal transduction. J. Exp. Med. 191: 1233-1240.
26. DiDonato, J. A., M. Hayakawa, D. M. Rothwarf, E. Zandi, and M. Karin. 1997. A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB. Nature 388: 548-554. (Pubitemid 27339997)
27. McWhirter, S. M., K. A. Fitzgerald, J. Rosains, D. C. Rowe, D. T. Golenbock, and T. Maniatis. 2004. IFN-regulatory factor 3-dependent gene expression is defective in Tbk1-deficient mouse embryonic fibroblasts. Proc. Natl. Acad. Sci. USA 101: 233-238. (Pubitemid 38084233)
28. Thévenod, F., J. M. Friedmann, A. D. Katsen, and I. A. Hauser. 2000. Upregulation of multidrug resistance P-glycoprotein via nuclear factor-kappaB activation protects kidney proximal tubule cells from cadmium- and reactive oxygen species-induced apoptosis. J. Biol. Chem. 275: 1887-1896. (Pubitemid 30060813)
29. Datta, S., M. Novotny, X. Li, J. Tebo, and T. A. Hamilton. 2004. Toll IL-1 receptors differ in their ability to promote the stabilization of adenosine and uridine-rich elements containing mRNA. J. Immunol. 173: 2755-2761. (Pubitemid 39063137)
30. Wan, Y., H. Xiao, J. Affolter, T. W. Kim, K. Bulek, S. Chaudhuri, D. Carlson, T. Hamilton, B. Mazumder, G. R. Stark, et al. 2009. Interleukin-1 receptor-associated kinase 2 is critical for lipopolysaccharide-mediated post-transcriptional control. J. Biol. Chem. 284: 10367-10375.
31. Sato, S., M. Sugiyama, M. Yamamoto, Y. Watanabe, T. Kawai, K. Takeda, and S. Akira. 2003. Toll/IL-1 receptor domain-containing adaptor inducing IFN-beta (TRIF) associates with TNF receptor-associated factor 6 and TANK-binding kinase 1, and activates two distinct transcription factors, NF-kappa B and IFN-regulatory factor-3, in the Toll-like receptor signaling. J. Immunol. 171: 4304-4310. (Pubitemid 37238709)
32. Jiang, Z., M. Zamanian-Daryoush, H. Nie, A. M. Silva, B. R. Williams, and X. Li. 2003. Poly(I-C)-induced*Toll-like receptor 3 (TLR3)-mediated activation of NFkappa B and MAP kinase is through an interleukin-1 receptor-associated kinase (IRAK)-independent pathway employing the signaling components TLR3-TRAF6-TAK1-TAB2-PKR. J. Biol. Chem. 278: 16713-16719. (Pubitemid 36799536)
33. Kawai, T., and S. Akira. 2007. Antiviral signaling through pattern recognition receptors. J. Biochem. 141: 137-145. (Pubitemid 46775751)
34. Ramaswamy, M., D. J. Groskreutz, and D. C. Look. 2009. Recognizing the importance of respiratory syncytial virus in chronic obstructive pulmonary disease. COPD 6: 64-75.
35. Di Stefano, A., G. Caramori, I. Gnemmi, M. Contoli, C. Vicari, A. Capelli, F. Magno, S. E. D'Anna, A. Zanini, P. Brun, et al. 2009. T helper type 17-related cytokine expression is increased in the bronchial mucosa of stable chronic obstructive pulmonary disease patients. Clin. Exp. Immunol. 157: 316-324.
36. Doe, C., M. Bafadhel, S. Siddiqui, D. Desai, V. Mistry, P. Rugman, M. McCormick, R. May, M. A. Sleeman, I. K. Anderson, and C. E. Brightling. 2010. Expression of the T helper 17-associated cytokines IL-17A and IL-17F in asthma and COPD. Chest 138: 1140-1147.
37. Tournadre, A., V. Lenief, and P. Miossec. 2010. Expression of Toll-like receptor 3 and Toll-like receptor 7 in muscle is characteristic of inflammatory myopathy and is differentially regulated by Th1 and Th17 cytokines. Arthritis Rheum. 62: 2144-2151.
38. Smith, E., K. M. Prasad, M. Butcher, A. Dobrian, J. K. Kolls, K. Ley, and E. Galkina. 2010. Blockade of interleukin-17A results in reduced atherosclerosis in apolipoprotein E-deficient mice. Circulation 121: 1746-1755.
39. Mukherjee, S., D. M. Lindell, A. A. Berlin, S. B. Morris, T. P. Shanley, M. B. Hershenson, and N. W. Lukacs. 2011. IL-17-induced pulmonary pathogenesis during respiratory viral infection and exacerbation of allergic disease. Am. J. Pathol. 179: 248-258.