Analysis by liquid chromatography-mass spectrometry of sterols and oxysterols in brain of the newborn Dhcr7D3-5/T93M mouse: A model of Smith-Lemli-Opitz syndrome

Biochemical Pharmacology

Volumn 86, Issue 1, 2013, Pages 43-55

  Meljon, Anna ^a   Watson, Gordon L ^b   Wang, Yuqin ^a   Shackleton, Cedric H L ^b   Griffiths, William J ^a  

^a SWANSEA UNIVERSITY   (United Kingdom)

^b CHILDREN S HOSPITAL OAKLAND RESEARCH INSTITUTE   (United States)

Author keywords

3 Hydroxysterol D7 reductase; 7 Dehydrocholesterol; 7 Dehydrodesmosterol; Cholesterol; Hydroxy 7 dehydrocholesterol

Indexed keywords

24R HYDROXYCHOLESTEROL; 24S 25 EPOXYCHOLESTEROL; 24S HYDROXYCHOLESTEROL; 25 HYDROXYCHOLESTEROL; 26 HYDROXYCHOLESTEROL; 7 DEHYDROCHOLESTEROL; 7 DEHYDRODESMOSTEROL; 7 OXOCHOLESTEROL; 8 DEHYDROCHOLESTEROL; 8 DEHYDRODESMOSTEROL; BRAIN EXTRACT; CHOLESTEROL; CHOLESTEROL DERIVATIVE; CHOLESTEROL OXIDASE; DESMOSTEROL; OXYSTEROL; REACTIVE OXYGEN METABOLITE; STEROL; UNCLASSIFIED DRUG; 7 DEHYDROCHOLESTEROL REDUCTASE; 7-DEHYDROCHOLESTEROL REDUCTASE; OXIDOREDUCTASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOOXIDATION; BRAIN; CHOLESTEROL METABOLISM; CHOLESTEROL SYNTHESIS; CONTROLLED STUDY; DOWN REGULATION; EMBRYO; ENZYME ACTIVITY; FEMALE; GENE MUTATION; GENOTYPE; HETEROZYGOTE; HYDROLYSIS; HYDROXYLATION; LIMIT OF DETECTION; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; METHANOLYSIS; MOUSE; NEWBORN; NONHUMAN; NULL ALLELE; PRIORITY JOURNAL; SMITH LEMLI OPITZ SYNDROME; WILD TYPE; ANIMAL; ELECTROSPRAY MASS SPECTROMETRY; GENE TARGETING; GENETICS; METABOLISM; MOUSE MUTANT; OXIDATION REDUCTION REACTION;

ANIMALS; ANIMALS, NEWBORN; CHOLESTEROL; CHROMATOGRAPHY, LIQUID; DESMOSTEROL; GENE KNOCK-IN TECHNIQUES; MICE; MICE, MUTANT STRAINS; OXIDATION-REDUCTION; OXIDOREDUCTASES ACTING ON CH-CH GROUP DONORS; SMITH-LEMLI-OPITZ SYNDROME; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; STEROLS;

EID: 84884342485     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2013.03.003     Document Type: Article

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