메뉴 건너뛰기




Volumn 68, Issue , 2013, Pages 199-220

The enduring centrality of dopamine in the pathophysiology of schizophrenia. In vivo evidence from the prodrome to the first psychotic episode.

Author keywords

Cause; Dopamine; Etiology; Onset; Pathophysiology; Prodrome; Psychosis; Schizophrenia

Indexed keywords

AMPHETAMINE; CHLORPROMAZINE; DOPAMINE; DOPAMINE 2 RECEPTOR; DOPAMINE 3 RECEPTOR; DOPAMINE C 11; DOPAMINE F 18; DOPAMINE TRANSPORTER; IODOBENZAMIDE I 123; NEUROLEPTIC AGENT; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG; VESICULAR MONOAMINE TRANSPORTER 2;

EID: 84884325284     PISSN: 10543589     EISSN: 15578925     Source Type: Book Series    
DOI: 10.1016/B978-0-12-411512-5.00010-5     Document Type: Chapter
Times cited : (19)

References (122)
  • 3
    • 67349207461 scopus 로고    scopus 로고
    • Baseline and amphetamine-stimulated dopamine activity are related in drug-naive schizophrenic subjects
    • Abi-Dargham A., van de Giessen E., Slifstein M., Kegeles L.S., Laruelle M. Baseline and amphetamine-stimulated dopamine activity are related in drug-naive schizophrenic subjects. Biological Psychiatry 2009, 65:1091-1093.
    • (2009) Biological Psychiatry , vol.65 , pp. 1091-1093
    • Abi-Dargham, A.1    van de Giessen, E.2    Slifstein, M.3    Kegeles, L.S.4    Laruelle, M.5
  • 4
    • 0032859516 scopus 로고    scopus 로고
    • Comparison of ketamine-induced thought disorder in healthy volunteers and thought disorder in schizophrenia
    • Adler C.M., Malhotra A.K., Elman I., Goldberg T., Egan M., Pickar D., et al. Comparison of ketamine-induced thought disorder in healthy volunteers and thought disorder in schizophrenia. The American Journal of Psychiatry 1999, 156:1646-1649.
    • (1999) The American Journal of Psychiatry , vol.156 , pp. 1646-1649
    • Adler, C.M.1    Malhotra, A.K.2    Elman, I.3    Goldberg, T.4    Egan, M.5    Pickar, D.6
  • 5
    • 84869010512 scopus 로고    scopus 로고
    • Transition to psychosis associated with prefrontal and subcortical dysfunction in ultra high-risk individuals
    • Allen P., Luigjes J., Howes O.D., Egerton A., Hirao K., Valli I., et al. Transition to psychosis associated with prefrontal and subcortical dysfunction in ultra high-risk individuals. Schizophrenia Bulletin 2012, 38:1268-1276.
    • (2012) Schizophrenia Bulletin , vol.38 , pp. 1268-1276
    • Allen, P.1    Luigjes, J.2    Howes, O.D.3    Egerton, A.4    Hirao, K.5    Valli, I.6
  • 9
    • 0029003189 scopus 로고
    • A longitudinal study of symptom dimensions in schizophrenia. Prediction and patterns of change
    • Arndt S., Andreasen N.C., Flaum M., Miller D., Nopoulos P. A longitudinal study of symptom dimensions in schizophrenia. Prediction and patterns of change. Archives of General Psychiatry 1995, 52:352-360.
    • (1995) Archives of General Psychiatry , vol.52 , pp. 352-360
    • Arndt, S.1    Andreasen, N.C.2    Flaum, M.3    Miller, D.4    Nopoulos, P.5
  • 10
    • 67849101387 scopus 로고    scopus 로고
    • Neuropsychological abnormalities in schizophrenia and major mood disorders: Similarities and differences
    • Barch D.M. Neuropsychological abnormalities in schizophrenia and major mood disorders: Similarities and differences. Current Psychiatry Reports 2009, 11:313-319.
    • (2009) Current Psychiatry Reports , vol.11 , pp. 313-319
    • Barch, D.M.1
  • 11
    • 0032423613 scopus 로고    scopus 로고
    • What is the role of dopamine in reward: Hedonic impact, reward learning, or incentive salience?
    • Berridge K.C., Robinson T.E. What is the role of dopamine in reward: Hedonic impact, reward learning, or incentive salience?. Brain Research. Brain Research Reviews 1998, 28:309-369.
    • (1998) Brain Research. Brain Research Reviews , vol.28 , pp. 309-369
    • Berridge, K.C.1    Robinson, T.E.2
  • 14
    • 1942420878 scopus 로고    scopus 로고
    • Animal models of obstetric complications in relation to schizophrenia
    • Boksa P. Animal models of obstetric complications in relation to schizophrenia. Brain Research. Brain Research Reviews 2004, 45:1-17.
    • (2004) Brain Research. Brain Research Reviews , vol.45 , pp. 1-17
    • Boksa, P.1
  • 15
    • 0038069367 scopus 로고    scopus 로고
    • Birth insult interacts with stress at adulthood to alter dopaminergic function in animal models: Possible implications for schizophrenia and other disorders
    • Boksa P., El-Khodor B.F. Birth insult interacts with stress at adulthood to alter dopaminergic function in animal models: Possible implications for schizophrenia and other disorders. Neuroscience and Biobehavioral Reviews 2003, 27:91-101.
    • (2003) Neuroscience and Biobehavioral Reviews , vol.27 , pp. 91-101
    • Boksa, P.1    El-Khodor, B.F.2
  • 21
    • 34248378758 scopus 로고    scopus 로고
    • The contribution of social factors to the development of schizophrenia: A review of recent findings
    • Cantor-Graae E. The contribution of social factors to the development of schizophrenia: A review of recent findings. Canadian Journal of Psychiatry 2007, 52:277-286.
    • (2007) Canadian Journal of Psychiatry , vol.52 , pp. 277-286
    • Cantor-Graae, E.1
  • 22
    • 78651116398 scopus 로고
    • Effect of chlorpromazine or haloperidol on the formation of 3-methoxytyramine and normetanephrine in mouse brain
    • Carlsson A., Lindqvist M. Effect of chlorpromazine or haloperidol on the formation of 3-methoxytyramine and normetanephrine in mouse brain. Acta Pharmacologica et Toxicologica 1963, 20:140-144.
    • (1963) Acta Pharmacologica et Toxicologica , vol.20 , pp. 140-144
    • Carlsson, A.1    Lindqvist, M.2
  • 23
    • 0000428532 scopus 로고
    • 3,4-Dihydroxyphenylalanine and 5-hydroxytryptophan as reserpine antagonists
    • Carlsson A., Lindqvist M., Magnusson T. 3,4-Dihydroxyphenylalanine and 5-hydroxytryptophan as reserpine antagonists. Nature 1957, 180:1200.
    • (1957) Nature , vol.180 , pp. 1200
    • Carlsson, A.1    Lindqvist, M.2    Magnusson, T.3
  • 24
    • 84874509464 scopus 로고    scopus 로고
    • Striatal dopamine transporter availability in drug-naive patients with schizophrenia: A case-control SPECT study with [(99m)Tc]-TRODAT-1 and a meta-analysis
    • Chen K.C., Yang Y.K., Howes O., Lee I.H., Landau S., Yeh T.L., et al. Striatal dopamine transporter availability in drug-naive patients with schizophrenia: A case-control SPECT study with [(99m)Tc]-TRODAT-1 and a meta-analysis. Schizophrenia Bulletin 2013, 39:378-386.
    • (2013) Schizophrenia Bulletin , vol.39 , pp. 378-386
    • Chen, K.C.1    Yang, Y.K.2    Howes, O.3    Lee, I.H.4    Landau, S.5    Yeh, T.L.6
  • 25
    • 0017255979 scopus 로고
    • Dopamine receptor binding predicts clinical and pharmacological potencies of antischizophrenic drugs
    • Creese I., Burt D., Snyder S. Dopamine receptor binding predicts clinical and pharmacological potencies of antischizophrenic drugs. Science 1976, 192:481-483.
    • (1976) Science , vol.192 , pp. 481-483
    • Creese, I.1    Burt, D.2    Snyder, S.3
  • 26
    • 70349571011 scopus 로고    scopus 로고
    • Superior temporal lobe dysfunction and frontotemporal dysconnectivity in subjects at risk of psychosis and in first-episode psychosis
    • Crossley N.A., Mechelli A., Fusar-Poli P., Broome M.R., Matthiasson P., Johns L.C., et al. Superior temporal lobe dysfunction and frontotemporal dysconnectivity in subjects at risk of psychosis and in first-episode psychosis. Human Brain Mapping 2009, 30:4129-4137.
    • (2009) Human Brain Mapping , vol.30 , pp. 4129-4137
    • Crossley, N.A.1    Mechelli, A.2    Fusar-Poli, P.3    Broome, M.R.4    Matthiasson, P.5    Johns, L.C.6
  • 31
    • 0024430178 scopus 로고
    • D1- and D2-dopamine receptor occupancy during treatment with conventional and atypical neuroleptics
    • Farde L., Wiesel F.A., Nordstrom A.L., Sedvall G. D1- and D2-dopamine receptor occupancy during treatment with conventional and atypical neuroleptics. Psychopharmacology 1989, 99(Suppl.):S28-S31.
    • (1989) Psychopharmacology , vol.99 , Issue.SUPPL.
    • Farde, L.1    Wiesel, F.A.2    Nordstrom, A.L.3    Sedvall, G.4
  • 34
    • 77954470531 scopus 로고    scopus 로고
    • Abnormal frontostriatal interactions in people with prodromal signs of psychosis: A multimodal imaging study
    • Fusar-Poli P., Howes O.D., Allen P., Broome M., Valli I., Asselin M.C., et al. Abnormal frontostriatal interactions in people with prodromal signs of psychosis: A multimodal imaging study. Archives of General Psychiatry 2010, 67:683-691.
    • (2010) Archives of General Psychiatry , vol.67 , pp. 683-691
    • Fusar-Poli, P.1    Howes, O.D.2    Allen, P.3    Broome, M.4    Valli, I.5    Asselin, M.C.6
  • 35
    • 78650512465 scopus 로고    scopus 로고
    • Abnormal prefrontal activation directly related to pre-synaptic striatal dopamine dysfunction in people at clinical high risk for psychosis
    • Fusar-Poli P., Howes O.D., Allen P., Broome M., Valli I., Asselin M.C., et al. Abnormal prefrontal activation directly related to pre-synaptic striatal dopamine dysfunction in people at clinical high risk for psychosis. Molecular Psychiatry 2011, 16:67-75.
    • (2011) Molecular Psychiatry , vol.16 , pp. 67-75
    • Fusar-Poli, P.1    Howes, O.D.2    Allen, P.3    Broome, M.4    Valli, I.5    Asselin, M.C.6
  • 36
    • 84871835435 scopus 로고    scopus 로고
    • Striatal presynaptic dopamine in schizophrenia, part I: Meta-analysis of dopamine active transporter (DAT) density
    • Fusar-Poli P., Meyer-Lindenberg A. Striatal presynaptic dopamine in schizophrenia, part I: Meta-analysis of dopamine active transporter (DAT) density. Schizophrenia Bulletin 2013, 39:22-32.
    • (2013) Schizophrenia Bulletin , vol.39 , pp. 22-32
    • Fusar-Poli, P.1    Meyer-Lindenberg, A.2
  • 37
    • 84871834419 scopus 로고    scopus 로고
    • Striatal presynaptic dopamine in schizophrenia, part II: Meta-analysis of [(18)F/(11)C]-DOPA PET studies
    • Fusar-Poli P., Meyer-Lindenberg A. Striatal presynaptic dopamine in schizophrenia, part II: Meta-analysis of [(18)F/(11)C]-DOPA PET studies. Schizophrenia Bulletin 2013, 39:33-42.
    • (2013) Schizophrenia Bulletin , vol.39 , pp. 33-42
    • Fusar-Poli, P.1    Meyer-Lindenberg, A.2
  • 38
    • 80052554378 scopus 로고    scopus 로고
    • Thalamic glutamate levels as a predictor of cortical response during executive functioning in subjects at high risk for psychosis
    • Fusar-Poli P., Stone J.M., Broome M.R., Valli I., Mechelli A., McLean M.A., et al. Thalamic glutamate levels as a predictor of cortical response during executive functioning in subjects at high risk for psychosis. Archives of General Psychiatry 2011, 68:881-890.
    • (2011) Archives of General Psychiatry , vol.68 , pp. 881-890
    • Fusar-Poli, P.1    Stone, J.M.2    Broome, M.R.3    Valli, I.4    Mechelli, A.5    McLean, M.A.6
  • 39
    • 84878646038 scopus 로고    scopus 로고
    • At risk for schizophrenic or affective psychosis? A meta-analysis of ICD/DSM diagnostic outcomes in individuals at high clinical risk
    • Fusar-Poli, P., Bechdolf, A., Taylor, M., Bonoldi, I., Carpenter, W., Yung, A., et al. (in press). At risk for schizophrenic or affective psychosis? A meta-analysis of ICD/DSM diagnostic outcomes in individuals at high clinical risk. Schizophrenia Bulletin, 39, 923-932.
    • Schizophrenia Bulletin , vol.39 , pp. 923-932
    • Fusar-Poli, P.1    Bechdolf, A.2    Taylor, M.3    Bonoldi, I.4    Carpenter, W.5    Yung, A.6
  • 40
    • 84871989449 scopus 로고    scopus 로고
    • (in press). The psychosis high risk state: A comprehensive state of the art review. Archives of General Psychiatry
    • Fusar-Poli, P., Borgwardt, S., Bechdolf, A., Addington, J., Riecher-Rössler, A., Schultze-Lutter, F., et al. (in press). The psychosis high risk state: A comprehensive state of the art review. Archives of General Psychiatry, 70, 107-120.
    • , vol.70 , pp. 107-120
    • Fusar-Poli, P.1    Borgwardt, S.2    Bechdolf, A.3    Addington, J.4    Riecher-Rössler, A.5    Schultze-Lutter, F.6
  • 41
    • 18544372627 scopus 로고    scopus 로고
    • Beyond hypofrontality: A quantitative meta-analysis of functional neuroimaging studies of working memory in schizophrenia
    • Glahn D.C., Ragland J.D., Abramoff A., Barrett J., Laird A.R., Bearden C.E., et al. Beyond hypofrontality: A quantitative meta-analysis of functional neuroimaging studies of working memory in schizophrenia. Human Brain Mapping 2005, 25:60-69.
    • (2005) Human Brain Mapping , vol.25 , pp. 60-69
    • Glahn, D.C.1    Ragland, J.D.2    Abramoff, A.3    Barrett, J.4    Laird, A.R.5    Bearden, C.E.6
  • 42
    • 0028170808 scopus 로고
    • Distribution of D1- and D2-dopamine receptors, and dopamine and its metabolites in the human brain
    • Hall H., Sedvall G., Magnusson O., Kopp J., Halldin C., Farde L. Distribution of D1- and D2-dopamine receptors, and dopamine and its metabolites in the human brain. Neuropsychopharmacology 1994, 11:245-256.
    • (1994) Neuropsychopharmacology , vol.11 , pp. 245-256
    • Hall, H.1    Sedvall, G.2    Magnusson, O.3    Kopp, J.4    Halldin, C.5    Farde, L.6
  • 44
    • 0033008487 scopus 로고    scopus 로고
    • Maternal deprivation of neonatal rats produces enduring changes in dopamine function
    • Hall F.S., Wilkinson L.S., Humby T., Robbins T.W. Maternal deprivation of neonatal rats produces enduring changes in dopamine function. Synapse 1999, 32:37-43.
    • (1999) Synapse , vol.32 , pp. 37-43
    • Hall, F.S.1    Wilkinson, L.S.2    Humby, T.3    Robbins, T.W.4
  • 45
    • 77953227595 scopus 로고    scopus 로고
    • Dopaminergic dysfunction in schizophrenia: Salience attribution revisited
    • Heinz A., Schlagenhauf F. Dopaminergic dysfunction in schizophrenia: Salience attribution revisited. Schizophrenia Bulletin 2010, 36:472-485.
    • (2010) Schizophrenia Bulletin , vol.36 , pp. 472-485
    • Heinz, A.1    Schlagenhauf, F.2
  • 47
    • 0028805490 scopus 로고
    • Presynaptic dopamine function in striatum of neuroleptic-naive schizophrenic patients
    • Hietala J., Syvalahti E., Vuorio K., Rakkolainen V., Bergman J., Haaparanta M., et al. Presynaptic dopamine function in striatum of neuroleptic-naive schizophrenic patients. Lancet 1995, 346:1130-1131.
    • (1995) Lancet , vol.346 , pp. 1130-1131
    • Hietala, J.1    Syvalahti, E.2    Vuorio, K.3    Rakkolainen, V.4    Bergman, J.5    Haaparanta, M.6
  • 49
    • 80052068381 scopus 로고    scopus 로고
    • Progressive increase in striatal dopamine synthesis capacity as patients develop psychosis: A PET study
    • Howes O., Bose S., Turkheimer F., Valli I., Egerton A., Stahl D., et al. Progressive increase in striatal dopamine synthesis capacity as patients develop psychosis: A PET study. Molecular Psychiatry 2011, 16:885-886.
    • (2011) Molecular Psychiatry , vol.16 , pp. 885-886
    • Howes, O.1    Bose, S.2    Turkheimer, F.3    Valli, I.4    Egerton, A.5    Stahl, D.6
  • 52
    • 65349120160 scopus 로고    scopus 로고
    • The dopamine hypothesis of schizophrenia: Version III - The final common pathway
    • Howes O., Kapur S. The dopamine hypothesis of schizophrenia: Version III - The final common pathway. Schizophrenia Bulletin 2009, 35:549-562.
    • (2009) Schizophrenia Bulletin , vol.35 , pp. 549-562
    • Howes, O.1    Kapur, S.2
  • 53
    • 37249083413 scopus 로고    scopus 로고
    • Molecular imaging studies of the striatal dopaminergic system in psychosis and predictions for the prodromal phase of psychosis
    • Howes O.D., Montgomery A.J., Asselin M., Murray R., Grasby P., McGuire P. Molecular imaging studies of the striatal dopaminergic system in psychosis and predictions for the prodromal phase of psychosis. The British Journal of Psychiatry 2007, s51:s13-s18.
    • (2007) The British Journal of Psychiatry , vol.51
    • Howes, O.D.1    Montgomery, A.J.2    Asselin, M.3    Murray, R.4    Grasby, P.5    McGuire, P.6
  • 56
    • 0024848601 scopus 로고
    • The concept of basic symptoms in schizophrenic and schizoaffective psychoses
    • Huber G., Gross G. The concept of basic symptoms in schizophrenic and schizoaffective psychoses. Recenti Progressi in Medicina 1989, 80:646-652.
    • (1989) Recenti Progressi in Medicina , vol.80 , pp. 646-652
    • Huber, G.1    Gross, G.2
  • 58
    • 0004256430 scopus 로고
    • The John Hopkins University Press, London, (tr. Hoenig, J & Hamilton, M)
    • Jaspers K. General psychopathology 1959/1963, The John Hopkins University Press, London, (tr. Hoenig, J & Hamilton, M).
    • (1959) General psychopathology
    • Jaspers, K.1
  • 59
    • 0025952455 scopus 로고
    • Recent advances in the phencyclidine model of schizophrenia
    • Javitt D.C., Zukin S.R. Recent advances in the phencyclidine model of schizophrenia. The American Journal of Psychiatry 1991, 148:1301-1308.
    • (1991) The American Journal of Psychiatry , vol.148 , pp. 1301-1308
    • Javitt, D.C.1    Zukin, S.R.2
  • 60
    • 33745741423 scopus 로고    scopus 로고
    • Dysfunction of ventral striatal reward prediction in schizophrenic patients treated with typical, not atypical, neuroleptics
    • Juckel G., Schlagenhauf F., Koslowski M., Filonov D., Wustenberg T., Villringer A., et al. Dysfunction of ventral striatal reward prediction in schizophrenic patients treated with typical, not atypical, neuroleptics. Psychopharmacology 2006, 187:222-228.
    • (2006) Psychopharmacology , vol.187 , pp. 222-228
    • Juckel, G.1    Schlagenhauf, F.2    Koslowski, M.3    Filonov, D.4    Wustenberg, T.5    Villringer, A.6
  • 61
    • 0037223711 scopus 로고    scopus 로고
    • Psychosis as a state of aberrant salience: A framework linking biology, phenomenology, and pharmacology in schizophrenia
    • Kapur S. Psychosis as a state of aberrant salience: A framework linking biology, phenomenology, and pharmacology in schizophrenia. The American Journal of Psychiatry 2003, 160:13-23.
    • (2003) The American Journal of Psychiatry , vol.160 , pp. 13-23
    • Kapur, S.1
  • 62
    • 25444483073 scopus 로고    scopus 로고
    • From dopamine to salience to psychosis-linking biology, pharmacology and phenomenology of psychosis
    • Kapur S., Mizrahi R., Li M. From dopamine to salience to psychosis-linking biology, pharmacology and phenomenology of psychosis. Schizophrenia Research 2005, 79:59-68.
    • (2005) Schizophrenia Research , vol.79 , pp. 59-68
    • Kapur, S.1    Mizrahi, R.2    Li, M.3
  • 63
    • 0032982714 scopus 로고    scopus 로고
    • Clinical and theoretical implications of 5-HT2 and D2 receptor occupancy of clozapine, risperidone, and olanzapine in schizophrenia
    • Kapur S., Zipursky R.B., Remington G. Clinical and theoretical implications of 5-HT2 and D2 receptor occupancy of clozapine, risperidone, and olanzapine in schizophrenia. The American Journal of Psychiatry 1999, 156:286-293.
    • (1999) The American Journal of Psychiatry , vol.156 , pp. 286-293
    • Kapur, S.1    Zipursky, R.B.2    Remington, G.3
  • 65
    • 32344435859 scopus 로고    scopus 로고
    • Transient and selective overexpression of dopamine D2 receptors in the striatum causes persistent abnormalities in prefrontal cortex functioning
    • Kellendonk C., Simpson E.H., Polan H.J., Malleret G., Vronskaya S., Winiger V., et al. Transient and selective overexpression of dopamine D2 receptors in the striatum causes persistent abnormalities in prefrontal cortex functioning. Neuron 2006, 49:603-615.
    • (2006) Neuron , vol.49 , pp. 603-615
    • Kellendonk, C.1    Simpson, E.H.2    Polan, H.J.3    Malleret, G.4    Vronskaya, S.5    Winiger, V.6
  • 68
    • 71949123177 scopus 로고    scopus 로고
    • PET studies of cerebral levodopa metabolism: A review of clinical findings and modeling approaches
    • Kumakura Y., Cumming P. PET studies of cerebral levodopa metabolism: A review of clinical findings and modeling approaches. The Neuroscientist 2009, 15:635-650.
    • (2009) The Neuroscientist , vol.15 , pp. 635-650
    • Kumakura, Y.1    Cumming, P.2
  • 69
    • 0032987267 scopus 로고    scopus 로고
    • Increased dopamine transmission in schizophrenia: Relationship to illness phases
    • Laruelle M., Abi-Dargham A., Gil R., Kegeles L., Innis R. Increased dopamine transmission in schizophrenia: Relationship to illness phases. Biological Psychiatry 1999, 46:56-72.
    • (1999) Biological Psychiatry , vol.46 , pp. 56-72
    • Laruelle, M.1    Abi-Dargham, A.2    Gil, R.3    Kegeles, L.4    Innis, R.5
  • 71
    • 0033952193 scopus 로고    scopus 로고
    • Dopamine and serotonin transporters in patients with schizophrenia: An imaging study with [(123)I]beta-CIT
    • Laruelle M., Abi-Dargham A., van Dyck C., Gil R., D'Souza D.C., Krystal J., et al. Dopamine and serotonin transporters in patients with schizophrenia: An imaging study with [(123)I]beta-CIT. Biological Psychiatry 2000, 47:371-379.
    • (2000) Biological Psychiatry , vol.47 , pp. 371-379
    • Laruelle, M.1    Abi-Dargham, A.2    van Dyck, C.3    Gil, R.4    D'Souza, D.C.5    Krystal, J.6
  • 72
    • 0035903772 scopus 로고    scopus 로고
    • Asymmetrical reductions of hippocampal NMDAR1 glutamate receptor mRNA in the psychoses
    • Law A.J., Deakin J.F. Asymmetrical reductions of hippocampal NMDAR1 glutamate receptor mRNA in the psychoses. Neuroreport 2001, 12:2971-2974.
    • (2001) Neuroreport , vol.12 , pp. 2971-2974
    • Law, A.J.1    Deakin, J.F.2
  • 73
    • 0023103235 scopus 로고
    • Provocative tests with psychostimulant drugs in schizophrenia
    • Lieberman J.A., Kane J.M., Alvir J. Provocative tests with psychostimulant drugs in schizophrenia. Psychopharmacology 1987, 91:415-433.
    • (1987) Psychopharmacology , vol.91 , pp. 415-433
    • Lieberman, J.A.1    Kane, J.M.2    Alvir, J.3
  • 74
    • 0025305036 scopus 로고
    • Dopaminergic mechanisms in idiopathic and drug-induced psychoses
    • Lieberman J.A., Kinon B.J., Loebel A.D. Dopaminergic mechanisms in idiopathic and drug-induced psychoses. Schizophrenia Bulletin 1990, 16:97-110.
    • (1990) Schizophrenia Bulletin , vol.16 , pp. 97-110
    • Lieberman, J.A.1    Kinon, B.J.2    Loebel, A.D.3
  • 76
    • 19544370227 scopus 로고    scopus 로고
    • The hippocampal-VTA loop: Controlling the entry of information into long-term memory
    • Lisman J.E., Grace A.A. The hippocampal-VTA loop: Controlling the entry of information into long-term memory. Neuron 2005, 46:703-713.
    • (2005) Neuron , vol.46 , pp. 703-713
    • Lisman, J.E.1    Grace, A.A.2
  • 77
    • 35448996395 scopus 로고    scopus 로고
    • Aberrant hippocampal activity underlies the dopamine dysregulation in an animal model of schizophrenia
    • Lodge D.J., Grace A.A. Aberrant hippocampal activity underlies the dopamine dysregulation in an animal model of schizophrenia. Journal of Neuroscience 2007, 27:11424-11430.
    • (2007) Journal of Neuroscience , vol.27 , pp. 11424-11430
    • Lodge, D.J.1    Grace, A.A.2
  • 78
    • 80052035263 scopus 로고    scopus 로고
    • Hippocampal dysregulation of dopamine system function and the pathophysiology of schizophrenia
    • Lodge D.J., Grace A.A. Hippocampal dysregulation of dopamine system function and the pathophysiology of schizophrenia. Trends in Pharmacological Sciences 2011, 32:507-513.
    • (2011) Trends in Pharmacological Sciences , vol.32 , pp. 507-513
    • Lodge, D.J.1    Grace, A.A.2
  • 80
    • 0035144117 scopus 로고    scopus 로고
    • Decreased presynaptic dopamine function in the left caudate of depressed patients with affective flattening and psychomotor retardation
    • Martinot M., Bragulat V., Artiges E., Dolle F., Hinnen F., Jouvent R., et al. Decreased presynaptic dopamine function in the left caudate of depressed patients with affective flattening and psychomotor retardation. The American Journal of Psychiatry 2001, 158:314-316.
    • (2001) The American Journal of Psychiatry , vol.158 , pp. 314-316
    • Martinot, M.1    Bragulat, V.2    Artiges, E.3    Dolle, F.4    Hinnen, F.5    Jouvent, R.6
  • 84
    • 0842321883 scopus 로고    scopus 로고
    • Prodromal assessment with the structured interview for prodromal syndromes and the scale of prodromal symptoms: Predictive validity, interrater reliability, and training to reliability
    • Miller T.J., McGlashan T.H., Rosen J.L., Cadenhead K., Cannon T., Ventura J., et al. Prodromal assessment with the structured interview for prodromal syndromes and the scale of prodromal symptoms: Predictive validity, interrater reliability, and training to reliability. Schizophrenia Bulletin 2003, 29:703-715.
    • (2003) Schizophrenia Bulletin , vol.29 , pp. 703-715
    • Miller, T.J.1    McGlashan, T.H.2    Rosen, J.L.3    Cadenhead, K.4    Cannon, T.5    Ventura, J.6
  • 88
    • 78650298401 scopus 로고    scopus 로고
    • Ultra high risk (UHR) for psychosis criteria: Are there different levels of risk for transition to psychosis?
    • Nelson B., Yuen K., Yung A.R. Ultra high risk (UHR) for psychosis criteria: Are there different levels of risk for transition to psychosis?. Schizophrenia Research 2011, 125:62-68.
    • (2011) Schizophrenia Research , vol.125 , pp. 62-68
    • Nelson, B.1    Yuen, K.2    Yung, A.R.3
  • 89
    • 0028991822 scopus 로고
    • D1, D2, and 5-HT2 receptor occupancy in relation to clozapine serum concentration: A PET study of schizophrenic patients
    • Nordstrom A.L., Farde L., Nyberg S., Karlsson P., Halldin C., Sedvall G. D1, D2, and 5-HT2 receptor occupancy in relation to clozapine serum concentration: A PET study of schizophrenic patients. The American Journal of Psychiatry 1995, 152:1444-1449.
    • (1995) The American Journal of Psychiatry , vol.152 , pp. 1444-1449
    • Nordstrom, A.L.1    Farde, L.2    Nyberg, S.3    Karlsson, P.4    Halldin, C.5    Sedvall, G.6
  • 91
    • 0037464759 scopus 로고    scopus 로고
    • Neuroanatomical abnormalities before and after onset of psychosis: A cross-sectional and longitudinal MRI comparison
    • Pantelis C., Velakoulis D., McGorry P.D., Wood S.J., Suckling J., Phillips L.J., et al. Neuroanatomical abnormalities before and after onset of psychosis: A cross-sectional and longitudinal MRI comparison. Lancet 2003, 361:281-288.
    • (2003) Lancet , vol.361 , pp. 281-288
    • Pantelis, C.1    Velakoulis, D.2    McGorry, P.D.3    Wood, S.J.4    Suckling, J.5    Phillips, L.J.6
  • 92
    • 34948858402 scopus 로고    scopus 로고
    • Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: A randomized Phase 2 clinical trial
    • Patil S.T., Zhang L., Martenyi F., Lowe S.L., Jackson K.A., Andreev B.V., et al. Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: A randomized Phase 2 clinical trial. Nature Medicine 2007, 13:1102-1107.
    • (2007) Nature Medicine , vol.13 , pp. 1102-1107
    • Patil, S.T.1    Zhang, L.2    Martenyi, F.3    Lowe, S.L.4    Jackson, K.A.5    Andreev, B.V.6
  • 94
    • 0242382831 scopus 로고    scopus 로고
    • Dopamine transporter: Basic aspects and neuroimaging
    • Piccini P.P. Dopamine transporter: Basic aspects and neuroimaging. Movement Disorders 2003, 18(Suppl. 7):S3-S8.
    • (2003) Movement Disorders , vol.18 , Issue.SUPPL. 7
    • Piccini, P.P.1
  • 96
    • 0019190758 scopus 로고
    • Effect of lesion of cortical dopamine terminals on subcortical dopamine receptors in rats
    • Pycock C.J., Kerwin R.W., Carter C.J. Effect of lesion of cortical dopamine terminals on subcortical dopamine receptors in rats. Nature 1980, 286:74-76.
    • (1980) Nature , vol.286 , pp. 74-76
    • Pycock, C.J.1    Kerwin, R.W.2    Carter, C.J.3
  • 97
    • 34547624096 scopus 로고    scopus 로고
    • Neuroimaging of cognitive disability in schizophrenia: Search for a pathophysiological mechanism
    • Ragland J.D., Yoon J., Minzenberg M.J., Carter C.S. Neuroimaging of cognitive disability in schizophrenia: Search for a pathophysiological mechanism. International Review of Psychiatry 2007, 19:417-427.
    • (2007) International Review of Psychiatry , vol.19 , pp. 417-427
    • Ragland, J.D.1    Yoon, J.2    Minzenberg, M.J.3    Carter, C.S.4
  • 100
    • 22144432283 scopus 로고    scopus 로고
    • A systematic review of the prevalence of schizophrenia
    • Saha S., Chant D., Welham J., McGrath J. A systematic review of the prevalence of schizophrenia. PLoS Medicine 2005, 2:e141.
    • (2005) PLoS Medicine , vol.2
    • Saha, S.1    Chant, D.2    Welham, J.3    McGrath, J.4
  • 101
    • 84876084495 scopus 로고    scopus 로고
    • Imaging patients with psychosis and a mouse model establishes a spreading pattern of hippocampal dysfunction and implicates glutamate as a driver
    • Schobel S.A., Chaudhury N.H., Khan U.A., Paniagua B., Styner M.A., Asllani I., et al. Imaging patients with psychosis and a mouse model establishes a spreading pattern of hippocampal dysfunction and implicates glutamate as a driver. Neuron 2013, 78:81-93.
    • (2013) Neuron , vol.78 , pp. 81-93
    • Schobel, S.A.1    Chaudhury, N.H.2    Khan, U.A.3    Paniagua, B.4    Styner, M.A.5    Asllani, I.6
  • 102
    • 0037057755 scopus 로고    scopus 로고
    • Getting formal with dopamine and reward
    • Schultz W. Getting formal with dopamine and reward. Neuron 2002, 36:241-263.
    • (2002) Neuron , vol.36 , pp. 241-263
    • Schultz, W.1
  • 103
    • 0030896968 scopus 로고    scopus 로고
    • A neural substrate of prediction and reward
    • Schultz W., Dayan P., Montague P.R. A neural substrate of prediction and reward. Science 1997, 275:1593-1599.
    • (1997) Science , vol.275 , pp. 1593-1599
    • Schultz, W.1    Dayan, P.2    Montague, P.R.3
  • 104
    • 84870736284 scopus 로고    scopus 로고
    • Glutamate neurocircuitry: Theoretical underpinnings in schizophrenia
    • Schwartz T.L., Sachdeva S., Stahl S.M. Glutamate neurocircuitry: Theoretical underpinnings in schizophrenia. Frontiers in Pharmacology 2012, 3:195.
    • (2012) Frontiers in Pharmacology , vol.3 , pp. 195
    • Schwartz, T.L.1    Sachdeva, S.2    Stahl, S.M.3
  • 105
    • 0016592484 scopus 로고
    • Antipsychotic drugs: Direct correlation between clinical potency and presynaptic action on dopamine neurons
    • Seeman P., Lee T. Antipsychotic drugs: Direct correlation between clinical potency and presynaptic action on dopamine neurons. Science 1975, 188:1217-1219.
    • (1975) Science , vol.188 , pp. 1217-1219
    • Seeman, P.1    Lee, T.2
  • 108
    • 70349420811 scopus 로고    scopus 로고
    • Abnormal thalamic glutamate and liability to psychosis: State or trait marker?
    • Stone J.M., Fusar-Poli P. Abnormal thalamic glutamate and liability to psychosis: State or trait marker?. Schizophrenia Research 2009, 115:94-95.
    • (2009) Schizophrenia Research , vol.115 , pp. 94-95
    • Stone, J.M.1    Fusar-Poli, P.2
  • 109
    • 77956934157 scopus 로고    scopus 로고
    • Altered relationship between hippocampal glutamate levels and striatal dopamine function in subjects at ultra high risk of psychosis
    • Stone J.M., Howes O.D., Egerton A., Kambeitz J., Allen P., Lythgoe D.J., et al. Altered relationship between hippocampal glutamate levels and striatal dopamine function in subjects at ultra high risk of psychosis. Biological Psychiatry 2010, 68:599-602.
    • (2010) Biological Psychiatry , vol.68 , pp. 599-602
    • Stone, J.M.1    Howes, O.D.2    Egerton, A.3    Kambeitz, J.4    Allen, P.5    Lythgoe, D.J.6
  • 110
    • 70349760191 scopus 로고    scopus 로고
    • Prefrontal cognitive systems in schizophrenia: Towards human genetic brain mechanisms
    • Tan H.Y., Callicott J.H., Weinberger D.R. Prefrontal cognitive systems in schizophrenia: Towards human genetic brain mechanisms. Cognitive Neuropsychiatry 2009, 14:277-298.
    • (2009) Cognitive Neuropsychiatry , vol.14 , pp. 277-298
    • Tan, H.Y.1    Callicott, J.H.2    Weinberger, D.R.3
  • 112
    • 54249120358 scopus 로고    scopus 로고
    • Psychosocial stress and psychosis. A review of the neurobiological mechanisms and the evidence for gene-stress interaction
    • van Winkel R., Stefanis N.C., Myin-Germeys I. Psychosocial stress and psychosis. A review of the neurobiological mechanisms and the evidence for gene-stress interaction. Schizophrenia Bulletin 2008, 34:1095-1105.
    • (2008) Schizophrenia Bulletin , vol.34 , pp. 1095-1105
    • van Winkel, R.1    Stefanis, N.C.2    Myin-Germeys, I.3
  • 113
    • 0033567853 scopus 로고    scopus 로고
    • GBR12909 attenuates amphetamine-induced striatal dopamine release as measured by [(11)C]raclopride continuous infusion PET scans
    • Villemagne V.L., Wong D.F., Yokoi F., Stephane M., Rice K.C., Matecka D., et al. GBR12909 attenuates amphetamine-induced striatal dopamine release as measured by [(11)C]raclopride continuous infusion PET scans. Synapse 1999, 33:268-273.
    • (1999) Synapse , vol.33 , pp. 268-273
    • Villemagne, V.L.1    Wong, D.F.2    Yokoi, F.3    Stephane, M.4    Rice, K.C.5    Matecka, D.6
  • 114
    • 33750626892 scopus 로고    scopus 로고
    • Subjective and behavioural consequences of striatal dopamine depletion in schizophrenia-findings from an in vivo SPECT study
    • Voruganti L.N., Awad A.G. Subjective and behavioural consequences of striatal dopamine depletion in schizophrenia-findings from an in vivo SPECT study. Schizophrenia Research 2006, 88:179-186.
    • (2006) Schizophrenia Research , vol.88 , pp. 179-186
    • Voruganti, L.N.1    Awad, A.G.2
  • 115
    • 0024207207 scopus 로고
    • A critical appraisal of CSF monoamine metabolite studies in schizophrenia
    • Widerlov E. A critical appraisal of CSF monoamine metabolite studies in schizophrenia. Annals of the New York Academy of Sciences 1988, 537:309-323.
    • (1988) Annals of the New York Academy of Sciences , vol.537 , pp. 309-323
    • Widerlov, E.1
  • 116
    • 2642519680 scopus 로고    scopus 로고
    • Dopamine, learning and motivation
    • Wise R.A. Dopamine, learning and motivation. Nature Reviews Neuroscience 2004, 5:483-494.
    • (2004) Nature Reviews Neuroscience , vol.5 , pp. 483-494
    • Wise, R.A.1
  • 117
    • 18844448147 scopus 로고    scopus 로고
    • Hippocampal and anterior cingulate morphology in subjects at ultra-high-risk for psychosis: The role of family history of psychotic illness
    • Wood S.J., Yucel M., Velakoulis D., Phillips L.J., Yung A.R., Brewer W., et al. Hippocampal and anterior cingulate morphology in subjects at ultra-high-risk for psychosis: The role of family history of psychotic illness. Schizophrenia Research 2005, 75:295-301.
    • (2005) Schizophrenia Research , vol.75 , pp. 295-301
    • Wood, S.J.1    Yucel, M.2    Velakoulis, D.3    Phillips, L.J.4    Yung, A.R.5    Brewer, W.6
  • 118
    • 0036238627 scopus 로고    scopus 로고
    • PET study of [(18)F]6-fluoro-L-dopa uptake in neuroleptic- and mood-stabilizer-naive first-episode nonpsychotic mania: Effects of treatment with divalproex sodium
    • Yatham L.N., Liddle P.F., Shiah I.S., Lam R.W., Ngan E., Scarrow G., et al. PET study of [(18)F]6-fluoro-L-dopa uptake in neuroleptic- and mood-stabilizer-naive first-episode nonpsychotic mania: Effects of treatment with divalproex sodium. The American Journal of Psychiatry 2002, 159:768-774.
    • (2002) The American Journal of Psychiatry , vol.159 , pp. 768-774
    • Yatham, L.N.1    Liddle, P.F.2    Shiah, I.S.3    Lam, R.W.4    Ngan, E.5    Scarrow, G.6
  • 119
    • 0038694794 scopus 로고    scopus 로고
    • Morphology of the anterior cingulate cortex in young men at ultra-high risk of developing a psychotic illness
    • Yucel M., Wood S.J., Phillips L.J., Stuart G.W., Smith D.J., Yung A., et al. Morphology of the anterior cingulate cortex in young men at ultra-high risk of developing a psychotic illness. The British Journal of Psychiatry 2003, 182:518-524.
    • (2003) The British Journal of Psychiatry , vol.182 , pp. 518-524
    • Yucel, M.1    Wood, S.J.2    Phillips, L.J.3    Stuart, G.W.4    Smith, D.J.5    Yung, A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.