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Volumn 156, Issue 2, 1999, Pages 286-293

Clinical and theoretical implications of 5-HT2 and D2 receptor occupancy of clozapine, risperidone, and olanzapine in schizophrenia

Author keywords

[No Author keywords available]

Indexed keywords

CLOZAPINE; DOPAMINE 2 RECEPTOR; OLANZAPINE; PROLACTIN; RACLOPRIDE; RISPERIDONE; SEROTONIN 2 RECEPTOR; SETOPERONE;

EID: 0032982714     PISSN: 0002953X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (693)

References (47)
  • 1
    • 0026718710 scopus 로고
    • Positron emission tomographic analysis of central d1 and d2 dopamine receptor occupancy in patients treated with classical neuroleptics and clozapine: Relation to extrapyramidal side effects
    • Farde L, Nordstrom AL, Wiesel FA, Pauli S, Halldin C, Sedvall G: Positron emission tomographic analysis of central D1 and D2 dopamine receptor occupancy in patients treated with classical neuroleptics and clozapine: relation to extrapyramidal side effects. Arch Gen Psychiatry 1992; 49:538-544
    • (1992) Arch Gen Psychiatry , vol.49 , pp. 538-544
    • Farde, L.1    Nordstrom, A.L.2    Wiesel, F.A.3    Pauli, S.4    Halldin, C.5    Sedvall, G.6
  • 3
    • 0028982509 scopus 로고
    • D2 dopamine receptor occupancy during low-dose treatment with haloperidol decanoate
    • Nyberg S, Farde L, Halldin C, Dahl M-L, Bertilsson L: D2 dopamine receptor occupancy during low-dose treatment with haloperidol decanoate. Am J Psychiatry 1995; 152:173-178
    • (1995) Am J Psychiatry , vol.152 , pp. 173-178
    • Nyberg, S.1    Farde, L.2    Halldin, C.3    Dahl, M.-L.4    Bertilsson, L.5
  • 4
    • 0027520871 scopus 로고
    • Central D2-dopamine receptor occupancy in relation to antipsychotic drug effects - A double-blind PET study of schizophrenic patients
    • Nordstrom AL, Farde L, Wiesel FA, Forslund K, Pauli S, Halldin C, Uppfeldt G: Central D2-dopamine receptor occupancy in relation to antipsychotic drug effects - a double-blind PET study of schizophrenic patients. Biol Psychiatry 1993; 33: 227-235
    • (1993) Biol Psychiatry , vol.33 , pp. 227-235
    • Nordstrom, A.L.1    Farde, L.2    Wiesel, F.A.3    Forslund, K.4    Pauli, S.5    Halldin, C.6    Uppfeldt, G.7
  • 5
    • 0024426716 scopus 로고
    • Striatal dopamine receptor occupancy during and following withdrawal from neuroleptic treatment: Correlative evaluation by positron emission tomography and plasma prolactin levels
    • Baron JC, Martinot JL, Cambon H, Boulenger JR Poirier MF, Caillard V, Blin J, Huret JD, Loc'h C, Maziere B: Striatal dopamine receptor occupancy during and following withdrawal from neuroleptic treatment: correlative evaluation by positron emission tomography and plasma prolactin levels. Psychopharmacology (Berl) 1989; 99:463-472
    • (1989) Psychopharmacology (Berl) , vol.99 , pp. 463-472
    • Baron, J.C.1    Martinot, J.L.2    Cambon, H.3    Boulenger, J.R.4    Poirier, M.F.5    Caillard, V.6    Blin, J.7    Huret, J.D.8    Loc'h, C.9    Maziere, B.10
  • 8
    • 0028061401 scopus 로고
    • Towards more effective antipsychotic treatment
    • Kane JM, Freeman HL: Towards more effective antipsychotic treatment. Br J Psychiatry 1994; 165:22-31
    • (1994) Br J Psychiatry , vol.165 , pp. 22-31
    • Kane, J.M.1    Freeman, H.L.2
  • 9
    • 0028342655 scopus 로고
    • Risperidone in the treatment of schizophrenia
    • Marder SR, Meibach RC: Risperidone in the treatment of schizophrenia. Am J Psychiatry 1994; 151:825-835
    • (1994) Am J Psychiatry , vol.151 , pp. 825-835
    • Marder, S.R.1    Meibach, R.C.2
  • 10
    • 0030993030 scopus 로고    scopus 로고
    • Olanzapine versus haloperidol in the treatment of schizophrenia and schizoaffective and schizophreniform disorders: Results of an international collaborative trial
    • Tollefson GD, Beasley CM Jr, Tran PV, Street JS, Krueger JA, Tamura RN, Graffeo KA, Thieme ME: Olanzapine versus haloperidol in the treatment of schizophrenia and schizoaffective and schizophreniform disorders: results of an international collaborative trial. Am J Psychiatry 1997; 154:457-465
    • (1997) Am J Psychiatry , vol.154 , pp. 457-465
    • Tollefson, G.D.1    Beasley C.M., Jr.2    Tran, P.V.3    Street, J.S.4    Krueger, J.A.5    Tamura, R.N.6    Graffeo, K.A.7    Thieme, M.E.8
  • 12
    • 0030795988 scopus 로고    scopus 로고
    • Multiple fixed doses of "seroquel" (quetiapine) in patients with acute exacerbation of schizophrenia: A comparison with haloperidol and placebo
    • Arvanitis LA, Miller BG, Seroquel Trial 13 Study Group: Multiple fixed doses of "Seroquel" (quetiapine) in patients with acute exacerbation of schizophrenia: a comparison with haloperidol and placebo. Biol Psychiatry 1997; 42:233-246
    • (1997) Biol Psychiatry , vol.42 , pp. 233-246
    • Arvanitis, L.A.1    Miller, B.G.2
  • 13
    • 0024854809 scopus 로고
    • The ratios of serotonin-2 and dopamine-2 affinities differentiate atypical and typical antipsychotic drugs
    • Meltzer HY, Matsubara S, Lee JC: The ratios of serotonin-2 and dopamine-2 affinities differentiate atypical and typical antipsychotic drugs. Psychopharmacol Bull 1989; 25:390-392
    • (1989) Psychopharmacol Bull , vol.25 , pp. 390-392
    • Meltzer, H.Y.1    Matsubara, S.2    Lee, J.C.3
  • 14
    • 0024466603 scopus 로고
    • Classification of typical and atypical antipsychotic drugs on the basis of dopamine D-1, D-2 and serotonin-2 pKi values
    • Meltzer HY, Matsubara S, Lee JC: Classification of typical and atypical antipsychotic drugs on the basis of dopamine D-1, D-2 and serotonin-2 pKi values. J Pharmacol Exp Ther 1989; 251:238-246
    • (1989) J Pharmacol Exp Ther , vol.251 , pp. 238-246
    • Meltzer, H.Y.1    Matsubara, S.2    Lee, J.C.3
  • 15
    • 0031943647 scopus 로고    scopus 로고
    • A new framework for investigating antipsychotic action in humans: Lessons from PET imaging
    • Kapur S: A new framework for investigating antipsychotic action in humans: lessons from PET imaging. Mol Psychiatry 1998; 3:135-140
    • (1998) Mol Psychiatry , vol.3 , pp. 135-140
    • Kapur, S.1
  • 17
    • 0028798102 scopus 로고
    • Positron emission tomography studies on D-2 and 5-HT2 receptor binding in risperidone-treated schizophrenic patients
    • Farde L, Nyberg S, Oxenstierna G, Nakashima Y, Halldin C, Ericsson B: Positron emission tomography studies on D-2 and 5-HT2 receptor binding in risperidone-treated schizophrenic patients. J Clin Psychopharmacol 1995; 15:S19-S23
    • (1995) J Clin Psychopharmacol , vol.15
    • Farde, L.1    Nyberg, S.2    Oxenstierna, G.3    Nakashima, Y.4    Halldin, C.5    Ericsson, B.6
  • 19
    • 0029026941 scopus 로고
    • The D2 dopamine receptor occupancy of risperidone and its relationship to extrapyramidal symptoms: A PET study
    • Kapur S, Remington G, Zipursky RB, Wilson AA, Houle S: The D2 dopamine receptor occupancy of risperidone and its relationship to extrapyramidal symptoms: a PET study. Life Sci 1995; 57:PL103-PL107
    • (1995) Life Sci , vol.57
    • Kapur, S.1    Remington, G.2    Zipursky, R.B.3    Wilson, A.A.4    Houle, S.5
  • 24
    • 0030779049 scopus 로고    scopus 로고
    • Effects of iorazepam administration on striatal dopamine D-2 receptor binding characteristics in man - A positron emission tomography study
    • Hietala J, Kuoppamaki M, Nagren K, Lehikoinen P, Syvalahti E: Effects of Iorazepam administration on striatal dopamine D-2 receptor binding characteristics in man - a positron emission tomography study. Psychopharmacology (Berl) 1997; 132:361-365
    • (1997) Psychopharmacology (Berl) , vol.132 , pp. 361-365
    • Hietala, J.1    Kuoppamaki, M.2    Nagren, K.3    Lehikoinen, P.4    Syvalahti, E.5
  • 27
    • 0023820533 scopus 로고
    • [18F]setoperone: A new high-affinity ligand for positron emission tomography study of the serotonin-2 receptors in baboon brain in vivo
    • Blin J, Pappata S, Kiyosawa M, Crouzel C, Baron JC: [18F]Setoperone: a new high-affinity ligand for positron emission tomography study of the serotonin-2 receptors in baboon brain in vivo. Eur J Pharmacol 1988; 147:73-82
    • (1988) Eur J Pharmacol , vol.147 , pp. 73-82
    • Blin, J.1    Pappata, S.2    Kiyosawa, M.3    Crouzel, C.4    Baron, J.C.5
  • 28
    • 0025219770 scopus 로고
    • A method for the in vivo investigation of the serotonergic 5-HT2 receptors in the human cerebral cortex using positron emission tomography and 18F-labeled setoperone
    • Blin J, Sette G, Fiorelli M, Bletry O, Elghozi JL, Crouzel C, Baron JC: A method for the in vivo investigation of the serotonergic 5-HT2 receptors in the human cerebral cortex using positron emission tomography and 18F-labeled setoperone. J Neurochem 1990; 54:1744-1754
    • (1990) J Neurochem , vol.54 , pp. 1744-1754
    • Blin, J.1    Sette, G.2    Fiorelli, M.3    Bletry, O.4    Elghozi, J.L.5    Crouzel, C.6    Baron, J.C.7
  • 29
    • 0023274497 scopus 로고
    • Serotonin receptors in the human brain, IV: Autoradiographic mapping of serotonin-2 receptors
    • Pazos A, Probst A, Palacios JM: Serotonin receptors in the human brain, IV: autoradiographic mapping of serotonin-2 receptors. Neuroscience 1987; 21:123-139
    • (1987) Neuroscience , vol.21 , pp. 123-139
    • Pazos, A.1    Probst, A.2    Palacios, J.M.3
  • 30
    • 0030004584 scopus 로고    scopus 로고
    • Estimation of neocortical serotonin-2 receptor binding potential by single-dose fluorine-18-setoperone kinetic PET data analysis
    • Petil-Taboue MC, Landeau B, Osmont A, Tillet I, Barre L, Baron JC: Estimation of neocortical serotonin-2 receptor binding potential by single-dose fluorine-18-setoperone kinetic PET data analysis. J Nucl Med 1996; 37:95-104
    • (1996) J Nucl Med , vol.37 , pp. 95-104
    • Petil-Taboue, M.C.1    Landeau, B.2    Osmont, A.3    Tillet, I.4    Barre, L.5    Baron, J.C.6
  • 31
    • 0344849647 scopus 로고
    • Investigation of the dopamine system with positron emission tomography: General issues in modelling
    • Edited by Baron JC. Dordrecht, The Netherlands, Kluwer Academic
    • Mazoyer B: Investigation of the dopamine system with positron emission tomography: general issues in modelling, in Brain Dopaminergic Imaging With Positron Emission Tomography. Edited by Baron JC. Dordrecht, The Netherlands, Kluwer Academic, 1991, pp 65-83
    • (1991) Brain Dopaminergic Imaging With Positron Emission Tomography , pp. 65-83
    • Mazoyer, B.1
  • 32
    • 0031007725 scopus 로고    scopus 로고
    • Reliability of a simple non-invasive method for the evaluation of 5-HT2 receptors using [18F]-setoperone PET imaging
    • Kapur S, Jones C, DaSilva J, Wilson A, Houle S: Reliability of a simple non-invasive method for the evaluation of 5-HT2 receptors using [18F]-setoperone PET imaging. Nucl Med Commun 1997; 18:395-399
    • (1997) Nucl Med Commun , vol.18 , pp. 395-399
    • Kapur, S.1    Jones, C.2    DaSilva, J.3    Wilson, A.4    Houle, S.5
  • 34
    • 0026090267 scopus 로고
    • The assay of clozapine and n-desmethylclozapine in human plasma by high-performance liquid chromatography
    • Lovdahl MJ, Perry PJ, Miller DD: The assay of clozapine and N-desmethylclozapine in human plasma by high-performance liquid chromatography. Ther Drug Monit 1991; 13:69-72
    • (1991) Ther Drug Monit , vol.13 , pp. 69-72
    • Lovdahl, M.J.1    Perry, P.J.2    Miller, D.D.3
  • 36
    • 0031014718 scopus 로고    scopus 로고
    • A PET study of 5-HT2 and d-2 dopamine receptor occupancy induced by olanzapine in healthy subjects
    • Nyberg S, Farde L, Halldin C: A PET study of 5-HT2 and D-2 dopamine receptor occupancy induced by olanzapine in healthy subjects. Neuropsychopharmacology 1997; 16:1-7
    • (1997) Neuropsychopharmacology , vol.16 , pp. 1-7
    • Nyberg, S.1    Farde, L.2    Halldin, C.3
  • 37
    • 0030609108 scopus 로고    scopus 로고
    • A PET study of [C-11]FLB 457 binding to extrastriatal D-2-dopamine receptors in healthy subjects and antipsychotic drug-treated patients
    • Farde L, Suhara T, Nyberg S, Karlsson P, Nakashima Y, Hietala J, Halldin C: A PET study of [C-11]FLB 457 binding to extrastriatal D-2-dopamine receptors in healthy subjects and antipsychotic drug-treated patients. Psychopharmacology (Berl) 1997; 133:396-404
    • (1997) Psychopharmacology (Berl) , vol.133 , pp. 396-404
    • Farde, L.1    Suhara, T.2    Nyberg, S.3    Karlsson, P.4    Nakashima, Y.5    Hietala, J.6    Halldin, C.7
  • 38
    • 0032007608 scopus 로고    scopus 로고
    • Do novel antipsychotics have similar pharmacological characteristics? A review of the evidence
    • Arnt J, Skarsfeldt T: Do novel antipsychotics have similar pharmacological characteristics? a review of the evidence. Neuropsychopharmacology 1998; 18:63-101
    • (1998) Neuropsychopharmacology , vol.18 , pp. 63-101
    • Arnt, J.1    Skarsfeldt, T.2
  • 40
    • 0017599705 scopus 로고
    • Antischizophrenic drugs: Chronic treatment elevates dopamine receptor binding in brain
    • Burt DR, Creese I, Snyder SH: Antischizophrenic drugs: chronic treatment elevates dopamine receptor binding in brain. Science 1977; 196:326-328
    • (1977) Science , vol.196 , pp. 326-328
    • Burt, D.R.1    Creese, I.2    Snyder, S.H.3
  • 41
    • 0030612278 scopus 로고    scopus 로고
    • Differential regulation of D2 and D4 dopamine receptor mRNAs in the primate cerebral cortex vs neostriatum: Effects of chronic treatment with typical and atypical antipsychotic drugs
    • Lidow MS, Goldman-Rakic PS: Differential regulation of D2 and D4 dopamine receptor mRNAs in the primate cerebral cortex vs neostriatum: effects of chronic treatment with typical and atypical antipsychotic drugs. J Pharmacol Exp Ther 1997; 283:939-946
    • (1997) J Pharmacol Exp Ther , vol.283 , pp. 939-946
    • Lidow, M.S.1    Goldman-Rakic, P.S.2
  • 42
    • 0029903903 scopus 로고    scopus 로고
    • Response of patients with treatment-refractory schizophrenia to clozapine within three serum level ranges
    • VanderZwaag C, McGee M, McEvoy JP, Freudenreich O, Wilson WH, Cooper TB: Response of patients with treatment-refractory schizophrenia to clozapine within three serum level ranges. Am J Psychiatry 1996; 153:1579-1584
    • (1996) Am J Psychiatry , vol.153 , pp. 1579-1584
    • VanderZwaag, C.1    McGee, M.2    McEvoy, J.P.3    Freudenreich, O.4    Wilson, W.H.5    Cooper, T.B.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.