Beyond counts and shapes: Studying pathology of dendritic spines in the context of the surrounding neuropil through serial section electron microscopy

Neuroscience

Volumn 251, Issue , 2013, Pages 75-89

  Kuwajima, M ^a   Spacek, J ^b   Harris, K M ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^b CHARLES UNIVERSITY   (Czech Republic)

Author keywords

3D reconstruction; Connectome; Neuropil; Pathology; Scanning transmission electron microscopy; Ultrastructure

Indexed keywords

AMYLOID;

AGING; ASTROCYTE; BRAIN SIZE; CELL COUNT; CELL ORGANELLE; CELL SHAPE; CELL STRUCTURE; CYTOLOGY; DENDRITIC SPINE; DISEASE MODEL; DOWN SYNDROME; ELECTRON MICROSCOPY; HIPPOCAMPAL CA3 REGION; HIPPOCAMPAL MOSSY FIBER; HUMAN; IMAGE ANALYSIS; IMAGE RECONSTRUCTION; MENOPAUSE; MESIAL TEMPORAL LOBE EPILEPSY; MITOCHONDRION; NERVE CELL NETWORK; NEUROPATHOLOGY; NEUROPIL; NONHUMAN; PARKINSON DISEASE; PATHOLOGICAL ANATOMY; PATHOPHYSIOLOGY; PRESYNAPTIC NERVE; PRIORITY JOURNAL; REVIEW; SERIAL SECTION ELECTRON MICROSCOPY; SYNAPSE; SYNAPTIC TRANSMISSION; THREE DIMENSIONAL IMAGING; ULTRASTRUCTURE;

1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE; 3D; 3D RECONSTRUCTION; AD; ALZHEIMER'S DISEASE; AMYLOID Β; ATLUM; AUTOMATIC TAPE-COLLECTING LATHE ULTRAMICROTOME; AΒ; CCD; CHARGE-COUPLED DEVICE; CONNECTOME; DELAYED NONMATCHING-TO-SAMPLE; DNMS; DOWN'S SYNDROME; DS; ELECTRON MICROSCOPY; EM; FIB-SEM; FOCUSED ION BEAM-SEM; GABA; MEDIUM SPINY NEURONS; MESIAL TEMPORAL LOBE EPILEPSY; MPTP; MSB; MSNS; MTLE; MULTI-SYNAPTIC BOUTON; NEUROPIL; NON-SYNAPTIC BOUTON; NSB; PATHOLOGY; POSTSYNAPTIC DENSITY; PSD; SA; SBFSEM; SCANNING ELECTRON MICROSCOPY; SCANNING TRANSMISSION ELECTRON MICROSCOPY; SEM; SERIAL BLOCK FACE SEM; SERIAL SECTION ELECTRON MICROSCOPY; SPINE APPARATUS; SSEM; STEM; TEM; TEM CAMERA ARRAY; TEMCA; THREE-DIMENSIONAL; TRANSMISSION ELECTRON MICROSCOPY; ULTRASTRUCTURE; VESICULAR GLUTAMATE TRANSPORTER; VGLUT; Γ-AMINOBUTYLIC ACID;

BRAIN; DENDRITIC SPINES; MICROSCOPY, ELECTRON, SCANNING; NEUROPIL; SYNAPSES;

EID: 84884283576     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2012.04.061     Document Type: Review

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