Microwave assisted synthesis of dihydrobenzo[4,5]imidazo[1,2-a]pyrimidin-4- ones; Synthesis, in vitro antimicrobial and anticancer activities of novel coumarin substituted dihydrobenzo[4,5]imidazo[1,2-a]pyrimidin-4-ones

European Journal of Medicinal Chemistry

Volumn 69, Issue , 2013, Pages 316-322

  Puttaraju, Kallimeledoddi B ^a   Shivashankar, Kalegowda ^a   Chandra, ^b   Mahendra, M ^b   Rasal, Vijaykumar P ^c   Venkata Vivek, Ponnuru N ^c   Rai, Khushboo ^c   Chanu, Maibam Beebina ^c  

^a BANGALORE UNIVERSITY   (India)

^b UNIVERSITY OF MYSORE   (India)

^c K L E S S COLLEGE OF PHARMACY   (India)

Author keywords

4 Bromomethylcoumarins; Benzimidazole; Coumarins; Pyrimidine

Indexed keywords

10 (6 BROMO 2 OXO 2H CHROMEN 4 YLMETHYL) 2 ISOPROPYL 10H BENZO[4,5]IMIDAZO[1,2 A]PYRIMIDIN 4 ONE; 10 (6 CHLORO 2 OXO 2H CHROMEN 4 YLMETHYL) 2 ISOPROPYL 10H BENZO[4,5]IMIDAZO[1,2 A]PYRIMIDIN 4 ONE; 10 (6 FLUORO 2 OXO 2H CHROMEN 4 YLMETHYL) 2 ISOPROPYL 10H BENZO[4,5]IMIDAZO[1,2 A]PYRIMIDIN 4 ONE; 10 (6 FLUORO 2 OXO 2H CHROMEN 4 YLMETHYL) 2 TRIFLUOROMETHYL 10H BENZO[4,5]IMIDAZO[1,2 A]PYRIMIDIN 4 ONE; 10 (6 METHOXY 2 OXO 2H CHROMEN 4 YLMETHYL) 2 ISOPROPYL 10H BENZO[4,5]IMIDAZO[1,2 A]PYRIMIDIN 4 ONE; 10 (6 METHOXY 2 OXO 2H CHROMEN 4 YLMETHYL) 2 TRIFLUOROMETHYL 10H BENZO[4,5]IMIDAZO[1,2 A]PYRIMIDIN 4 ONE; 10 (6 METHYL 2 OXO 2H CHROMEN 4 YLMETHYL) 2 TRIFLUOROMETHYL 10H BENZO[4,5]IMIDAZO[1,2 A]PYRIMIDIN 4 ONE; 10 (6,8 DIMETHYL 2 OXO 2H CHROMEN 4 YLMETHYL) 2 TRIFLUOROMETHYL 10H BENZO[4,5]IMIDAZO[1,2 A]PYRIMIDIN 4 ONE; 2 (3 FLUORO PHENYL) 10H BENZO[4,5]IMIDAZO[1,2 A]PYRIMIDIN 4 ONE; 2 (4 TRIFLUOROMETHYL PHENYL) 10H BENZO[4,5]IMIDAZO[1,2 A]PYRIMIDIN 4 ONE; 2 ISOPROPYL 10H BENZO[4,5]IMIDAZO[1,2 A]PYRIMIDIN 4 ONE; CIPROFLOXACIN; COUMARIN DERIVATIVE; FLUCONAZOLE; FLUOROURACIL; PYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ANTIMICROBIAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; ASPERGILLUS FLAVUS; ASPERGILLUS FUMIGATUS; ASPERGILLUS NIGER; CANCER CELL CULTURE; CANDIDA ALBICANS; CHEMICAL STRUCTURE; DRUG STRUCTURE; DRUG SYNTHESIS; ENTEROCOCCUS FAECALIS; ESCHERICHIA COLI; FUSARIUM OXYSPORUM; IN VITRO STUDY; KLEBSIELLA PNEUMONIAE; LYMPHOMA CELL LINE; MICROWAVE IRRADIATION; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PENICILLIUM CHRYSOGENUM; PSEUDOMONAS AERUGINOSA; REACTION TIME; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS MUTANS;

4-BROMOMETHYLCOUMARINS; BENZIMIDAZOLE; COUMARINS; PYRIMIDINE;

ANTI-BACTERIAL AGENTS; ANTIFUNGAL AGENTS; ANTINEOPLASTIC AGENTS; BACTERIA; BENZIMIDAZOLES; CELL LINE, TUMOR; CELL PROLIFERATION; COUMARINS; DRUG SCREENING ASSAYS, ANTITUMOR; FUNGI; HUMANS; MICROBIAL SENSITIVITY TESTS; MICROWAVES; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PYRIMIDINONES;

EID: 84884270204     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2013.07.015     Document Type: Article

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