Synthesis and QSAR studies of novel 1-substituted-2-aminobenzimidazoles derivatives

European Journal of Medicinal Chemistry

Volumn 41, Issue 9, 2006, Pages 1080-1083

  Guida, Xuan ^a   Jianhua, Han ^a   Xiaomin, Li ^a  

^a ZHEJIANG UNIVERSITY CITY COLLEGE   (China)

Author keywords

2 aminobenzimidazole derivatives; Acute toxicity; QSAR; Synthesis

Indexed keywords

BENZIMIDAZOLE DERIVATIVE; OCTANOL; WATER; 2 AMINOBENZIMIDAZOLE; 2-AMINOBENZIMIDAZOLE;

ACUTE TOXICITY; ALKYLATION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOPSY; CONTROLLED STUDY; DRUG ACTIVITY; DRUG FATALITY; DRUG STRUCTURE; DRUG SYNTHESIS; FEMALE; JUMPING; LD 50; MALE; MELTING POINT; MOUSE; NEUROTOXICITY; NONHUMAN; PARTITION COEFFICIENT; PREDICTION; PROTON NUCLEAR MAGNETIC RESONANCE; QUANTITATIVE STRUCTURE ACTIVITY RELATION; REACTION TIME; RESTLESSNESS; STRUCTURE ANALYSIS; TREMOR; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; INSTITUTE FOR CANCER RESEARCH MOUSE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SYNTHESIS; TOXICITY TESTING;

ACUTE TOXICITY TESTS; ANIMALS; BENZIMIDAZOLES; FEMALE; LETHAL DOSE 50; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MICE; MICE, INBRED ICR; MOLECULAR STRUCTURE; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33748440935     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2006.01.002     Document Type: Article

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