Novel macrocyclic amidinoureas: Potent non-azole antifungals active against wild-type and resistant Candida species

ACS Medicinal Chemistry Letters

Volumn 4, Issue 9, 2013, Pages 852-857

  Sanguinetti, Maurizio ^c   Sanfilippo, Stefania ^a   Castagnolo, Daniele ^a,b   Sanglard, Dominique ^d   Posteraro, Brunella ^c   Donzellini, Giovanni ^a   Botta, Maurizio ^a,e  

^a UNIVERSITY OF SIENA   (Italy)

^b NORTHUMBRIA UNIVERSITY   (United Kingdom)

^c CATHOLIC UNIVERSITY   (Italy)

^d LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

^e Temple University   (United States)

Author keywords

amidinourea; Antifungal; antifungal drug resistance; Candida species; fluconazole; macrocyclization; ring closing metathesis

Indexed keywords

AMIDINE; AMPHOTERICIN B; ANTIFUNGAL AGENT; FLUCONAZOLE; UREA DERIVATIVE; VORICONAZOLE;

ANTIFUNGAL ACTIVITY; ARTICLE; CANDIDA; CYCLIZATION; DRUG SYNTHESIS; MINIMUM INHIBITORY CONCENTRATION; MYCOSIS; NONHUMAN; PRIORITY JOURNAL; RING CLOSING METATHESIS; SPECIES; WILD TYPE;

CANDIDA;

EID: 84884255152     PISSN: None     EISSN: 19485875     Source Type: Journal    
DOI: 10.1021/ml400187w     Document Type: Article

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