-
1
-
-
0025766081
-
Phospholipid transfer proteins
-
K. W. Wirtz, Phospholipid transfer proteins. Annu. Rev. Biochem. 60, 73-99 (1991).
-
(1991)
Annu. Rev. Biochem.
, vol.60
, pp. 73-99
-
-
Wirtz, K.W.1
-
2
-
-
0036349207
-
Clofibrate-induced relocation of phosphatidylcholine transfer protein to mitochondria in endothelial cells
-
A. P. M. de Brouwer, J. Westerman, A. Kleinnijenhuis, L. E. Bevers, B. Roelofsen, K. W. A. Wirtz, Clofibrate-induced relocation of phosphatidylcholine transfer protein to mitochondria in endothelial cells. Exp. Cell Res. 274, 100-111 (2002).
-
(2002)
Exp. Cell Res.
, vol.274
, pp. 100-111
-
-
De Brouwer, A.P.M.1
Westerman, J.2
Kleinnijenhuis, A.3
Bevers, L.E.4
Roelofsen, B.5
Wirtz, K.W.A.6
-
3
-
-
0036294612
-
Structure of human phosphatidylcholine transfer protein in complex with its ligand
-
DOI 10.1038/nsb812
-
S. L. Roderick, W. W. Chan, D. S. Agate, L. R. Olsen, M. W. Vetting, K. R. Rajashankar, D. E. Cohen, Structure of human phosphatidylcholine transfer protein in complex with its ligand. Nat. Struct. Biol. 9, 507-511 (2002). (Pubitemid 34693804)
-
(2002)
Nature Structural Biology
, vol.9
, Issue.7
, pp. 507-511
-
-
Roderick, S.L.1
Chan, W.W.2
Agate, D.S.3
Olsen, L.R.4
Vetting, M.W.5
Rajashankar, K.R.6
Cohen, D.E.7
-
5
-
-
46749102472
-
Regulation of energy substrate utilization and hepatic insulin sensitivity by phosphatidylcholine transfer protein/StarD2
-
DOI 10.1096/fj.07-105395
-
E. F. Scapa, A. Pocai, M. K.Wu, R. Gutierrez-Juarez, L. Glenz, K. Kanno, H. Li, S. Biddinger, L. A. Jelicks, L. Rossetti, D. E. Cohen, Regulation of energy substrate utilization and hepatic insulin sensitivity by phosphatidylcholine transfer protein/StarD2. FASEB J. 22, 2579-2590 (2008). (Pubitemid 351948675)
-
(2008)
FASEB Journal
, vol.22
, Issue.7
, pp. 2579-2590
-
-
Scapa, E.F.1
Pocai, A.2
Wu, M.K.3
Gutierrez-Juarez, R.4
Glenz, L.5
Kanno, K.6
Li, H.7
Biddinger, S.8
Jelicks, L.A.9
Rossetti, L.10
Cohen, D.E.11
-
6
-
-
79960726770
-
Genetic ablation or chemical inhibition of phosphatidylcholine transfer protein attenuates diet-induced hepatic glucose production
-
E. Y. Shishova, J. M. Stoll, B. A. Ersoy, S. Shrestha, E. F. Scapa, Y. X. Li, M. W. Niepel, Y. Su, L. A. Jelicks, G. L. Stahl, M. A. Glicksman, R. Gutierrez-Juarez, G. D. Cuny, D. E. Cohen, Genetic ablation or chemical inhibition of phosphatidylcholine transfer protein attenuates diet-induced hepatic glucose production. Hepatology 54, 664-674 (2011).
-
(2011)
Hepatology
, vol.54
, pp. 664-674
-
-
Shishova, E.Y.1
Stoll, J.M.2
Ersoy, B.A.3
Shrestha, S.4
Scapa, E.F.5
Li, Y.X.6
Niepel, M.W.7
Su, Y.8
Jelicks, L.A.9
Stahl, G.L.10
Glicksman, M.A.11
Gutierrez-Juarez, R.12
Cuny, G.D.13
Cohen, D.E.14
-
7
-
-
33751015133
-
A polymorphism in New Zealand inbred mouse strains that inactivates phosphatidylcholine transfer protein
-
DOI 10.1016/j.febslet.2006.09.066, PII S0014579306011884
-
H. J. Pan, D. S. Agate, B. L. King, M. K. Wu, S. L. Roderick, E. H. Leiter, D. E. Cohen, A polymorphism in New Zealand inbred mouse strains that inactivates phosphatidylcholine transfer protein. FEBS Lett. 580, 5953-5958 (2006). (Pubitemid 44739944)
-
(2006)
FEBS Letters
, vol.580
, Issue.25
, pp. 5953-5958
-
-
Pan, H.-J.1
Agate, D.S.2
King, B.L.3
Wu, M.K.4
Roderick, S.L.5
Leiter, E.H.6
Cohen, D.E.7
-
8
-
-
36048936408
-
Influences of the phosphatidylcholine transfer protein gene variants on the LDL peak particle size
-
DOI 10.1016/j.atherosclerosis.2007.01.002, PII S0021915007000421
-
G. Dolley, M. T. Berthier, B. Lamarche, J. P. Després, C. Bouchard, L. Pérusse, M. C. Vohl, Influences of the phosphatidylcholine transfer protein gene variants on the LDL peak particle size. Atherosclerosis 195, 297-302 (2007). (Pubitemid 350087959)
-
(2007)
Atherosclerosis
, vol.195
, Issue.2
, pp. 297-302
-
-
Dolley, G.1
Berthier, M.T.2
Lamarche, B.3
Despres, J.P.4
Bouchard, C.5
Perusse, L.6
Vohl, M.C.7
-
9
-
-
35648957162
-
Interacting proteins dictate function of the minimal START domain phosphatidylcholine transfer protein/StarD2
-
DOI 10.1074/jbc.M703745200
-
K. Kanno, M. K. Wu, D. A. Agate, B. K. Fanelli, N. Wagle, E. F. Scapa, C. Ukomadu, D. E. Cohen, Interacting proteins dictate function of the minimal START domain phosphatidylcholine transfer protein/StarD2. J. Biol. Chem. 282, 30728-30736 (2007). (Pubitemid 350035203)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.42
, pp. 30728-30736
-
-
Kanno, K.1
Wu, M.K.2
Agate, D.S.3
Fanelli, B.J.4
Wagle, N.5
Scapa, E.F.6
Ukomadu, C.7
Cohen, D.E.8
-
10
-
-
67650914857
-
Thioesterase superfamily member 2 (Them2)/acyl-CoA thioesterase 13 (Acot13): A homotetrameric hotdog fold thioesterase with selectivity for long-chain fatty acyl-CoAs
-
J. Wei, H.W. Kang, D. E. Cohen, Thioesterase superfamily member 2 (Them2)/acyl-CoA thioesterase 13 (Acot13): A homotetrameric hotdog fold thioesterase with selectivity for long-chain fatty acyl-CoAs. Biochem. J. 421, 311-322 (2009).
-
(2009)
Biochem. J.
, vol.421
, pp. 311-322
-
-
Wei, J.1
Kang, H.W.2
Cohen, D.E.3
-
11
-
-
76549119341
-
Regulatory role for phosphatidylcholine transfer protein/StarD2 in the metabolic response to peroxisome proliferator activated receptor alpha (PPARa)
-
H. W. Kang, K. Kanno, E. F. Scapa, D. E. Cohen, Regulatory role for phosphatidylcholine transfer protein/StarD2 in the metabolic response to peroxisome proliferator activated receptor alpha (PPARa). Biochim. Biophys. Acta 1801, 496-502 (2010).
-
(2010)
Biochim. Biophys. Acta
, vol.1801
, pp. 496-502
-
-
Kang, H.W.1
Kanno, K.2
Scapa, E.F.3
Cohen, D.E.4
-
12
-
-
84860908799
-
Thioesterase superfamily member 2/acyl-CoA thioesterase 13 (Them2/Acot13) regulates hepatic lipid and glucose metabolism
-
H. W. Kang, M. W. Niepel, S. Han, Y. Kawano, D. E. Cohen, Thioesterase superfamily member 2/acyl-CoA thioesterase 13 (Them2/Acot13) regulates hepatic lipid and glucose metabolism. FASEB J. 26, 2209-2221 (2012).
-
(2012)
FASEB J
, vol.26
, pp. 2209-2221
-
-
Kang, H.W.1
Niepel, M.W.2
Han, S.3
Kawano, Y.4
Cohen, D.E.5
-
13
-
-
0025813375
-
Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein
-
X. J. Sun, P. Rothenberg, C. R. Kahn, J. M. Backer, E. Araki, P. A. Wilden, D. A. Cahill, B. J. Goldstein, M. F. White, Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein. Nature 352, 73-77 (1991). (Pubitemid 21896701)
-
(1991)
Nature
, vol.352
, Issue.6330
, pp. 73-77
-
-
Sun, X.J.1
Rothenberg, P.2
Kahn, C.R.3
Backer, J.M.4
Araki, E.5
Wilden, P.A.6
Cahill, D.A.7
Goldstein, B.J.8
White, M.F.9
-
14
-
-
34047095297
-
The two TORCs and Akt
-
DOI 10.1016/j.devcel.2007.03.020, PII S1534580707001207
-
P. T. Bhaskar, N. Hay, The two TORCs and Akt. Dev. Cell 12, 487-502 (2007). (Pubitemid 46523652)
-
(2007)
Developmental Cell
, vol.12
, Issue.4
, pp. 487-502
-
-
Bhaskar, P.T.1
Hay, N.2
-
15
-
-
13844312400
-
Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex
-
DOI 10.1126/science.1106148
-
D. D. Sarbassov, D. A. Guertin, S. M. Ali, D. M. Sabatini, Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex. Science 307, 1098-1101 (2005). (Pubitemid 40262113)
-
(2005)
Science
, vol.307
, Issue.5712
, pp. 1098-1101
-
-
Sarbassov, D.D.1
Guertin, D.A.2
Ali, S.M.3
Sabatini, D.M.4
-
16
-
-
0141925771
-
Akt activity negatively regulates phosphorylation of AMP-activated protein kinase in the heart
-
DOI 10.1074/jbc.M305371200
-
S. Kovacic, C. L. Soltys, A. J. Barr, I. Shiojima, K. Walsh, J. R. Dyck, Akt activity negatively regulates phosphorylation of AMP-activated protein kinase in the heart. J. Biol. Chem. 278, 39422-39427 (2003). (Pubitemid 37248497)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.41
, pp. 39422-39427
-
-
Kovacic, S.1
Soltys, C.-L.M.2
Barr, A.J.3
Shiojima, I.4
Walsh, K.5
Dyck, J.R.B.6
-
17
-
-
0033534724
-
Control of glycogen synthesis in cultured human muscle cells
-
R. Halse, J. J. Rochford, J. G. McCormack, J. R. Vandenheede, B. A. Hemmings, S. J. Yeaman, Control of glycogen synthesis in cultured human muscle cells. J. Biol. Chem. 274, 776-780 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 776-780
-
-
Halse, R.1
Rochford, J.J.2
McCormack, J.G.3
Vandenheede, J.R.4
Hemmings, B.A.5
Yeaman, S.J.6
-
18
-
-
0036342294
-
Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/Akt pathway
-
DOI 10.1016/S1097-2765(02)00568-3
-
B. D. Manning, A. R. Tee, M. N. Logsdon, J. Blenis, L. C. Cantley, Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway. Mol. Cell 10, 151-162 (2002). (Pubitemid 34876569)
-
(2002)
Molecular Cell
, vol.10
, Issue.1
, pp. 151-162
-
-
Manning, B.D.1
Tee, A.R.2
Logsdon M.Nicole3
Blenis, J.4
Cantley, L.C.5
-
19
-
-
0038433304
-
Insulin activation of Rheb, a mediator of mTOR/S6K/4E-BP signaling, is inhibited by TSC1 and 2
-
DOI 10.1016/S1097-2765(03)00220-X
-
A. Garami, F. J. Zwartkruis, T. Nobukuni, M. Joaquin, M. Roccio, H. Stocker, S. C. Kozma, E. Hafen, J. L. Bos, G. Thomas, Insulin activation of Rheb, a mediator of mTOR/S6K/4E-BP signaling, is inhibited by TSC1 and 2. Mol. Cell 11, 1457-1466 (2003). (Pubitemid 36776533)
-
(2003)
Molecular Cell
, vol.11
, Issue.6
, pp. 1457-1466
-
-
Garami, A.1
Zwartkruis, F.J.T.2
Nobukuni, T.3
Joaquin, M.4
Roccio, M.5
Stocker, H.6
Kozma, S.C.7
Hafen, E.8
Bos, J.L.9
Thomas, G.10
-
20
-
-
52449106253
-
The identification of 2-(1H-indazol-4-yl) 6-(4-methanesulfonyl-piperazin- 1-ylmethyl)-4- morphol in-4-yl-thieno[3,2-d]pyrimidine (GDC-0941) as a potent, selective, orally bioavailable inhibitor of class i PI3 kinase for the treatment of cancer
-
A. J. Folkes, K. Ahmadi, W. K. Alderton, S. Alix, S. J. Baker, G. Box, I. S. Chuckowree, P. A. Clarke, P. Depledge, S. A. Eccles, L. S. Friedman, A. Hayes, T. C. Hancox, A. Kugendradas, L. Lensun, P. Moore, A. G. Olivero, J. Pang, S. Patel, G. H. Pergl-Wilson, F. I. Raynaud, A. Robson, N. Saghir, L. Salphati, S. Sohal, M. H. Ultsch, M. Valenti, H. J. A. Wallweber, N. C. Wan, C. Wiesmann, P. Workman, A. Zhyvoloup, M. J. Zvelebil, S. J. Shuttleworth, The identification of 2-(1H-indazol-4-yl)-6-(4-methanesulfonyl-piperazin-1-ylmethyl) -4- morphol in-4-yl-thieno[3,2-d]pyrimidine (GDC-0941) as a potent, selective, orally bioavailable inhibitor of class I PI3 kinase for the treatment of cancer. J. Med. Chem. 51, 5522-5532 (2008).
-
(2008)
J. Med. Chem.
, vol.51
, pp. 5522-5532
-
-
Folkes, A.J.1
Ahmadi, K.2
Alderton, W.K.3
Alix, S.4
Baker, S.J.5
Box, G.6
Chuckowree, I.S.7
Clarke, P.A.8
Depledge, P.9
Eccles, S.A.10
Friedman, L.S.11
Hayes, A.12
Hancox, T.C.13
Kugendradas, A.14
Lensun, L.15
Moore, P.16
Olivero, A.G.17
Pang, J.18
Patel, S.19
Pergl-Wilson, G.H.20
Raynaud, F.I.21
Robson, A.22
Saghir, N.23
Salphati, L.24
Sohal, S.25
Ultsch, M.H.26
Valenti, M.27
Wallweber, H.J.A.28
Wan, N.C.29
Wiesmann, C.30
Workman, P.31
Zhyvoloup, A.32
Zvelebil, M.J.33
Shuttleworth, S.J.34
more..
-
21
-
-
27744569843
-
MTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events
-
DOI 10.1016/j.cell.2005.10.024, PII S0092867405011578
-
M. K. Holz, B. A. Ballif, S. P. Gygi, J. Blenis, mTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events. Cell 123, 569-580 (2005). (Pubitemid 41608461)
-
(2005)
Cell
, vol.123
, Issue.4
, pp. 569-580
-
-
Holz, M.K.1
Ballif, B.A.2
Gygi, S.P.3
Blenis, J.4
-
22
-
-
0035856949
-
Insulin signalling and the regulation of glucose and lipid metabolism
-
DOI 10.1038/414799a
-
A. R. Saltiel, C. R. Kahn, Insulin signalling and the regulation of glucose and lipid metabolism. Nature 414, 799-806 (2001). (Pubitemid 34000783)
-
(2001)
Nature
, vol.414
, Issue.6865
, pp. 799-806
-
-
Saltiel, A.R.1
Kahn, C.R.2
-
24
-
-
0032475861
-
Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN
-
DOI 10.1016/S0092-8674(00)81780-8
-
V. Stambolic, A. Suzuki, J. L. de la Pompa, G. M. Brothers, C. Mirtsos, T. Sasaki, J. Ruland, J. M. Penninger, D. P. Siderovski, T. W. Mak, Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN. Cell 95, 29-39 (1998). (Pubitemid 28458022)
-
(1998)
Cell
, vol.95
, Issue.1
, pp. 29-39
-
-
Stambolic, V.1
Suzuki, A.2
De La Pompa, J.L.3
Brothers, G.M.4
Mirtsos, C.5
Sasaki, T.6
Ruland, J.7
Penninger, J.M.8
Siderovski, D.P.9
Mak, T.W.10
-
25
-
-
0034640524
-
Epidermal growth factor receptor-dependent Akt activation by oxidative stress enhances cell survival
-
DOI 10.1074/jbc.275.19.14624
-
X. T. Wang, K. D. McCullough, T. F. Franke, N. J. Holbrook, Epidermal growth factor receptor-dependent Akt activation by oxidative stress enhances cell survival. J. Biol. Chem. 275, 14624-14631 (2000). (Pubitemid 30339753)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.19
, pp. 14624-14631
-
-
Wang, X.1
McCullough, K.D.2
Franke, T.F.3
Holbrook, N.J.4
-
26
-
-
65649098029
-
Phosphorylation of IRS proteins, insulin action, and insulin resistance
-
S. Boura-Halfon, Y. Zick, Phosphorylation of IRS proteins, insulin action, and insulin resistance. Am. J. Physiol. Endocrinol. Metab. 296, E581-E591 (2009).
-
(2009)
Am. J. Physiol. Endocrinol. Metab.
, vol.296
-
-
Boura-Halfon, S.1
Zick, Y.2
-
27
-
-
84866122780
-
Regulation of insulin sensitivity by serine/threonine phosphorylation of insulin receptor substrate proteins IRS1 and IRS2
-
K. D. Copps, M. F. White, Regulation of insulin sensitivity by serine/threonine phosphorylation of insulin receptor substrate proteins IRS1 and IRS2. Diabetologia 55, 2565-2582 (2012).
-
(2012)
Diabetologia
, vol.55
, pp. 2565-2582
-
-
Copps, K.D.1
White, M.F.2
-
28
-
-
0030748457
-
The insulin signalling system and the IRS proteins
-
DOI 10.1007/s001250051387
-
M. F. White, The insulin signalling system and the IRS proteins. Diabetologia 40, S2-S17 (1997). (Pubitemid 27306917)
-
(1997)
Diabetologia
, vol.40
, Issue.SUPPL. 2
-
-
White, M.F.1
-
29
-
-
0037108750
-
Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling
-
DOI 10.1073/pnas.202476899
-
A. R. Tee, D. C. Fingar, B. D. Manning, D. J. Kwiatkowski, L. C. Cantley, J. Blenis, Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling. Proc. Natl. Acad. Sci. U.S.A. 99, 13571-13576 (2002). (Pubitemid 35215423)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.21
, pp. 13571-13576
-
-
Tee, A.R.1
Fingar, D.C.2
Manning, B.D.3
Kwiatkowski, D.J.4
Cantley, L.C.5
Blenis, J.6
-
30
-
-
0036712905
-
Tsc tumour suppressor proteins antagonize amino-acid-TOR signalling
-
DOI 10.1038/ncb847
-
X. S. Gao, Y. Zhang, P. Arrazola, O. Hino, T. Kobayashi, R. S. Yeung, B. G. Ru, D. J. Pan, Tsc tumour suppressor proteins antagonize amino-acid-TOR signalling. Nat. Cell Biol. 4, 699-704 (2002). (Pubitemid 34993706)
-
(2002)
Nature Cell Biology
, vol.4
, Issue.9
, pp. 699-704
-
-
Gao, X.1
Zhang, Y.2
Arrazola, P.3
Hino, O.4
Kobayashi, T.5
Yeung, R.S.6
Ru, B.7
Pan, D.8
-
31
-
-
84884259121
-
-
D. A. Agate, thesis, Albert Einstein College of Medicine, Bronx, NY (2006).
-
D. A. Agate, thesis, Albert Einstein College of Medicine, Bronx, NY (2006).
-
-
-
-
32
-
-
0032810826
-
Cloning and gene structure of rat phosphatidylcholine transfer protein, Pctp
-
DOI 10.1016/S0378-1119(99)00204-8, PII S0378111999002048
-
M. K.Wu,M.O.Boylan, D. E. Cohen, Cloning and gene structure of rat phosphatidylcholine transfer protein, Pctp. Gene 235, 111-120 (1999). (Pubitemid 29327288)
-
(1999)
Gene
, vol.235
, Issue.1-2
, pp. 111-120
-
-
Wu, M.K.1
Boylan, M.O.2
Cohen, D.E.3
-
33
-
-
40949091903
-
Structural and biochemical characterization of the KRLB region in insulin receptor substrate-2
-
DOI 10.1038/nsmb.1388, PII NSMB1388
-
J. H. Wu, Y. D. Tseng, C. F. Xu, T. A. Neubert, M. F. White, S. R. Hubbard, Structural and biochemical characterization of the KRLB region in insulin receptor substrate-2. Nat. Struct. Mol. Biol. 15, 251-258 (2008). (Pubitemid 351654043)
-
(2008)
Nature Structural and Molecular Biology
, vol.15
, Issue.3
, pp. 251-258
-
-
Wu, J.1
Tseng, Y.D.2
Xu, C.-F.3
Neubert, T.A.4
White, M.F.5
Hubbard, S.R.6
-
34
-
-
0025871767
-
Pro-Leu-Ser/Thr-Pro is a consensus primary sequence for substrate protein phosphorylation: Characterization of the phosphorylation of c-myc and c-jun proteins by an epidermal growth factor receptor threonine 669 protein kinase
-
E. Alvarez, I. C. Northwood, F. A. Gonzalez, D. A. Latour, A. Seth, C. Abate, T. Curran, R. J. Davis, Pro-Leu-Ser/Thr-Pro is a consensus primary sequence for substrate protein phosphorylation. Characterization of the phosphorylation of c-myc and c-jun proteins by an epidermal growth factor receptor threonine 669 protein kinase. J. Biol. Chem. 266, 15277-15285 (1991). (Pubitemid 21907645)
-
(1991)
Journal of Biological Chemistry
, vol.266
, Issue.23
, pp. 15277-15285
-
-
Alvarez, E.1
Northwood, I.C.2
Gonzalez, F.A.3
Latour, D.A.4
Seth, A.5
Abate, C.6
Curran, T.7
Davis, R.J.8
-
35
-
-
2342483040
-
SREBPs suppress IRS-2-mediated insulin signalling in the liver
-
DOI 10.1038/ncb1111
-
T. Ide, H. Shimano, N. Yahagi, T. Matsuzaka, M. Nakakuki, T. Yamamoto, Y. Nakagawa, A. Takahashi, H. Suzuki, H. Sone, H. Toyoshima, A. Fukamizu, N. Yamada, SREBPs suppress IRS-2-mediated insulin signalling in the liver. Nat. Cell Biol. 6, 351-357 (2004). (Pubitemid 38584825)
-
(2004)
Nature Cell Biology
, vol.6
, Issue.4
, pp. 351-357
-
-
Ide, T.1
Shimano, H.2
Yahagi, N.3
Matsuzaka, T.4
Nakakuki, M.5
Yamamoto, T.6
Nakagawa, Y.7
Takahashi, A.8
Suzuki, H.9
Sone, H.10
Toyoshima, H.11
Fukamizu, A.12
Yamada, N.13
-
36
-
-
44449161481
-
The TSC1-TSC2 complex: A molecular switchboard controlling cell growth
-
DOI 10.1042/BJ20080281
-
J. Huang, B. D. Manning, The TSC1-TSC2 complex: A molecular switchboard controlling cell growth. Biochem. J. 412, 179-190 (2008). (Pubitemid 351758225)
-
(2008)
Biochemical Journal
, vol.412
, Issue.2
, pp. 179-190
-
-
Huang, J.1
Manning, B.D.2
-
37
-
-
27744588780
-
Tuberous sclerosis: A GAP at the crossroads of multiple signaling pathways
-
DOI 10.1093/hmg/ddi260
-
D. J. Kwiatkowski, B. D. Manning, Tuberous sclerosis: A GAP at the crossroads of multiple signaling pathways. Hum. Mol. Genet. 14, R251-R258 (2005). (Pubitemid 41631882)
-
(2005)
Human Molecular Genetics
, vol.14
, Issue.SUPPL. 2
-
-
Kwiatkowski, D.J.1
Manning, B.D.2
-
38
-
-
17844369428
-
The tuberous sclerosis-1 (TSC1) gene product hamartin suppresses cell growth and augments the expression of the TSC2 product tuberin by inhibiting its ubiquitination
-
DOI 10.1038/sj.onc.1204009
-
G. Benvenuto, S. W. Li, S. J. Brown, R. Braverman,W. C. Vass, J. P. Cheadle, D. J. J. Halley, J. R. Sampson, R. Wienecke, J. E. DeClue, The tuberous sclerosis-1 (TSC1) gene product hamartin suppresses cell growth and augments the expression of the TSC2 product tuberin by inhibiting its ubiquitination. Oncogene 19, 6306-6316 (2000). (Pubitemid 32641844)
-
(2000)
Oncogene
, vol.19
, Issue.54
, pp. 6306-6316
-
-
Benvenuto, G.1
Li, S.2
Brown, S.J.3
Braverman, R.4
Vass, W.C.5
Cheadle, J.P.6
Halley, D.J.J.7
Sampson, J.R.8
Wienecke, R.9
DeClue, J.E.10
-
39
-
-
70350545722
-
Characterization of Rictor phosphorylation sites reveals direct regulation of mTOR complex 2 by S6K1
-
C. C. Dibble, J. M. Asara, B. D. Manning, Characterization of Rictor phosphorylation sites reveals direct regulation of mTOR complex 2 by S6K1. Mol. Cell. Biol. 29, 5657-5670 (2009).
-
(2009)
Mol. Cell. Biol.
, vol.29
, pp. 5657-5670
-
-
Dibble, C.C.1
Asara, J.M.2
Manning, B.D.3
-
40
-
-
24044506419
-
Impaired response of biliary lipid secretion to a lithogenic diet in phosphatidylcholine transfer protein-deficient mice
-
DOI 10.1194/jlr.M400387-JLR200
-
M. K. Wu, H. Hyogo, S. Yadav, P. M. Novikoff, D. E. Cohen, Impaired response of biliary lipid secretion to a lithogenic diet in phosphatidylcholine transfer protein-deficient mice. J. Lipid Res. 46, 422-431 (2005). (Pubitemid 43109777)
-
(2005)
Journal of Lipid Research
, vol.46
, Issue.3
, pp. 422-431
-
-
Wu, M.K.1
Hyogo, H.2
Yadav, S.K.3
Novikoff, P.M.4
Cohen, D.E.5
-
41
-
-
45549090182
-
Inactivation of hepatic foxo1 by insulin signaling is required for adaptive nutrient homeostasis and endocrine growth regulation
-
DOI 10.1016/j.cmet.2008.06.006, PII S1550413108001770
-
X. C. Dong, K. D. Copps, S. D. Guo, Y. D. Li, R. Kollipara, R. A. DePinho, M. F. White, Inactivation of hepatic Foxo1 by insulin signaling is required for adaptive nutrient homeostasis and endocrine growth regulation. Cell Metab. 8, 65-76 (2008). (Pubitemid 351863393)
-
(2008)
Cell Metabolism
, vol.8
, Issue.1
, pp. 65-76
-
-
Dong, X.C.1
Copps, K.D.2
Guo, S.3
Li, Y.4
Kollipara, R.5
DePinho, R.A.6
White, M.F.7
-
42
-
-
0034687723
-
High-level expression and mutagenesis of recombinant human phosphatidylcholine transfer protein using a synthetic gene: Evidence for a C-terminal membrane binding domain
-
DOI 10.1021/bi001076a
-
L. Feng, W. W. Chan, S. L. Roderick, D. E. Cohen, High-level expression and mutagenesis of recombinant human phosphatidylcholine transfer protein using a synthetic gene: Evidence for a C-terminal membrane binding domain. Biochemistry 39, 15399-15409 (2000). (Pubitemid 32002766)
-
(2000)
Biochemistry
, vol.39
, Issue.50
, pp. 15399-15409
-
-
Feng, L.1
Chan, W.W.2
Roderick, S.L.3
Cohen, D.E.4
-
43
-
-
34249813409
-
Structure and function of phosphatidylcholine transfer protein (PC-TP)/StarD2
-
DOI 10.1016/j.bbalip.2007.04.003, PII S1388198107000789, Lipid Transporters in Cell Biology
-
K. Kanno, M. K. Wu, E. F. Scapa, S. L. Roderick, D. E. Cohen, Structure and function of phosphatidylcholine transfer protein (PC-TP)/StarD2. Biochim. Biophys. Acta 1771, 654-662 (2007). (Pubitemid 46856894)
-
(2007)
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids
, vol.1771
, Issue.6
, pp. 654-662
-
-
Kanno, K.1
Wu, M.K.2
Scapa, E.F.3
Roderick, S.L.4
Cohen, D.E.5
-
44
-
-
0037178786
-
MTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery
-
DOI 10.1016/S0092-8674(02)00808-5
-
D. H. Kim, D. D. Sarbassov, S. M. Ali, J. E. King, R. R. Latek, H. Erdjument-Bromage, P. Tempst, D. M. Sabatini, mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery. Cell 110, 163-175 (2002). (Pubitemid 34876545)
-
(2002)
Cell
, vol.110
, Issue.2
, pp. 163-175
-
-
Kim, D.-H.1
Sarbassov, D.D.2
Ali, S.M.3
King, J.E.4
Latek, R.R.5
Erdjument-Bromage, H.6
Tempst, P.7
Sabatini, D.M.8
|