메뉴 건너뛰기




Volumn 26, Issue 5, 2012, Pages 2209-2221

Thioesterase superfamily member 2/acyl-CoA thioesterase 13 (Them2/Acot13) regulates hepatic lipid and glucose metabolism

Author keywords

Free fatty acid; Liver; Obesity

Indexed keywords

ACYL COENZYME A; FATTY ACID; GLUCOSE; HEPATOCYTE NUCLEAR FACTOR 4ALPHA; LECITHIN TRANSFER PROTEIN; LIPID; LIPID TRANSFER PROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; THIOESTERASE SUPERFAMILY MEMBER 2; THIOL ESTER HYDROLASE; UNCLASSIFIED DRUG;

EID: 84860908799     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.11-202853     Document Type: Article
Times cited : (52)

References (40)
  • 1
    • 0036138306 scopus 로고    scopus 로고
    • The role Acyl-CoA thioesterases play in mediating intracellular lipid metabolism
    • DOI 10.1016/S0163-7827(01)00017-0, PII S0163782701000170
    • Hunt, M. C., and Alexson, S. E. (2002) The role Acyl-CoA thioesterases play in mediating intracellular lipid metabolism. Prog. Lipid Res. 41, 99-130 (Pubitemid 34041023)
    • (2002) Progress in Lipid Research , vol.41 , Issue.2 , pp. 99-130
    • Hunt, M.C.1    Alexson, S.E.H.2
  • 2
    • 76049092146 scopus 로고    scopus 로고
    • Acyl-CoA synthesis, lipid metabolism and lipotoxicity
    • Li, L. O., Klett, E. L., and Coleman, R. A. (2010) Acyl-CoA synthesis, lipid metabolism and lipotoxicity. Biochim. Biophys. Acta 1801, 246-251
    • (2010) Biochim. Biophys. Acta , vol.1801 , pp. 246-251
    • Li, L.O.1    Klett, E.L.2    Coleman, R.A.3
  • 4
    • 85027930482 scopus 로고    scopus 로고
    • Evolutionary divergence and functions of the human acyl-CoA thioesterase gene (ACOT) family
    • Brocker, C., Carpenter, C., Nebert, D. W., and Vasiliou, V. (2010) Evolutionary divergence and functions of the human acyl-CoA thioesterase gene (ACOT) family. Hum. Genomics 4, 411-420
    • (2010) Hum. Genomics , vol.4 , pp. 411-420
    • Brocker, C.1    Carpenter, C.2    Nebert, D.W.3    Vasiliou, V.4
  • 5
    • 77956394560 scopus 로고    scopus 로고
    • Functional and structural properties of mammalian acyl-coenzyme A thioesterases
    • Kirkby, B., Roman, N., Kobe, B., Kellie, S., and Forwood, J. K. (2010) Functional and structural properties of mammalian acyl-coenzyme A thioesterases. Prog. Lipid Res. 49, 366-377
    • (2010) Prog. Lipid Res. , vol.49 , pp. 366-377
    • Kirkby, B.1    Roman, N.2    Kobe, B.3    Kellie, S.4    Forwood, J.K.5
  • 6
    • 67650914857 scopus 로고    scopus 로고
    • Thioesterase superfamily member 2 (Them2)/acyl-CoA thioesterase 13 (Acot13): A homotetrameric hotdog fold thioesterase with selectivity for long-chain fatty acyl-CoAs
    • Wei, J., Kang, H. W., and Cohen, D. E. (2009) Thioesterase superfamily member 2 (Them2)/acyl-CoA thioesterase 13 (Acot13): A homotetrameric hotdog fold thioesterase with selectivity for long-chain fatty acyl-CoAs. Biochem. J. 421, 311-322
    • (2009) Biochem. J. , vol.421 , pp. 311-322
    • Wei, J.1    Kang, H.W.2    Cohen, D.E.3
  • 7
    • 64349123693 scopus 로고    scopus 로고
    • The mechanisms of human hotdog-fold thioesterase 2 (hTHEM2) substrate recognition and catalysis illuminated by a structure and function based analysis
    • Cao, J., Xu, H., Zhao, H., Gong, W., and Dunaway-Mariano, D. (2009) The mechanisms of human hotdog-fold thioesterase 2 (hTHEM2) substrate recognition and catalysis illuminated by a structure and function based analysis. Biochemistry 48, 1293-1304
    • (2009) Biochemistry , vol.48 , pp. 1293-1304
    • Cao, J.1    Xu, H.2    Zhao, H.3    Gong, W.4    Dunaway-Mariano, D.5
  • 8
    • 35648957162 scopus 로고    scopus 로고
    • Interacting proteins dictate function of the minimal START domain phosphatidylcholine transfer protein/StarD2
    • DOI 10.1074/jbc.M703745200
    • Kanno, K., Wu, M. K., Agate, D. A., Fanelli, B. K., Wagle, N., Scapa, E. F., Ukomadu, C., and Cohen, D. E. (2007) Interacting proteins dictate function of the minimal START domain phosphatidylcholine transfer protein/StarD2. J. Biol. Chem. 282, 30728-30736 (Pubitemid 350035203)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.42 , pp. 30728-30736
    • Kanno, K.1    Wu, M.K.2    Agate, D.S.3    Fanelli, B.J.4    Wagle, N.5    Scapa, E.F.6    Ukomadu, C.7    Cohen, D.E.8
  • 9
    • 76549119341 scopus 로고    scopus 로고
    • Regulatory role for phosphatidylcholine transfer protein/ StarD2 in the metabolic response to peroxisome proliferator activated receptor alpha (PPARalpha)
    • Kang, H. W., Kanno, K., Scapa, E. F., and Cohen, D. E. (2010) Regulatory role for phosphatidylcholine transfer protein/ StarD2 in the metabolic response to peroxisome proliferator activated receptor alpha (PPARalpha). Biochim. Biophys. Acta 1801, 496-502
    • (2010) Biochim. Biophys. Acta , vol.1801 , pp. 496-502
    • Kang, H.W.1    Kanno, K.2    Scapa, E.F.3    Cohen, D.E.4
  • 10
    • 0036349207 scopus 로고    scopus 로고
    • Clofibrate-induced relocation of phosphatidylcholine transfer protein to mitochondria in endothelial cells
    • De Brouwer, A. P., Westerman, J., Kleinnijenhuis, A., Bevers, L. E., Roelofsen, B., and Wirtz, K. W. A. (2002) Clofibrate-induced relocation of phosphatidylcholine transfer protein to mitochondria in endothelial cells. Exp. Cell Res. 274, 100 -111
    • (2002) Exp. Cell Res. , vol.274 , pp. 100-111
    • De Brouwer, A.P.1    Westerman, J.2    Kleinnijenhuis, A.3    Bevers, L.E.4    Roelofsen, B.5    Wirtz, K.W.A.6
  • 11
  • 14
    • 0037072876 scopus 로고    scopus 로고
    • Leptin promotes biliary cholesterol elimination during weight loss in ob/ob mice by regulating the enterohepatic circulation of bile salts
    • Hyogo, H., Roy, S., Paigen, B., and Cohen, D. E. (2002) Leptin promotes biliary cholesterol elimination during weight loss in ob/ob mice by regulating the enterohepatic circulation of bile salts. J. Biol. Chem. 277, 34117-34124
    • (2002) J. Biol. Chem. , vol.277 , pp. 34117-34124
    • Hyogo, H.1    Roy, S.2    Paigen, B.3    Cohen, D.E.4
  • 15
    • 70350400603 scopus 로고    scopus 로고
    • Mice lacking phosphatidylcholine transfer protein/StarD2 exhibit increased adaptive thermogenesis and enlarged mitochondria in brown adipose tissue
    • Kang, H. W., Ribich, S., Kim, B. W., Hagen, S. J., Bianco, A. C., and Cohen, D. E. (2009) Mice lacking phosphatidylcholine transfer protein/StarD2 exhibit increased adaptive thermogenesis and enlarged mitochondria in brown adipose tissue. J. Lipid Res. 50, 2212-2221
    • (2009) J. Lipid Res. , vol.50 , pp. 2212-2221
    • Kang, H.W.1    Ribich, S.2    Kim, B.W.3    Hagen, S.J.4    Bianco, A.C.5    Cohen, D.E.6
  • 16
    • 34548164420 scopus 로고    scopus 로고
    • The acyl-CoA thioesterase I is regulated by PPARalpha and HNF4alpha via a distal response element in the promoter
    • DOI 10.1194/jlr.M700119-JLR200
    • Dongol, B., Shah, Y., Kim, I., Gonzalez, F. J., and Hunt, M. C. (2007) The acyl-CoA thioesterase I is regulated by PPARalpha and HNF4alpha via a distal response element in the promoter. J. Lipid Res. 48, 1781-1791 (Pubitemid 47311995)
    • (2007) Journal of Lipid Research , vol.48 , Issue.8 , pp. 1781-1791
    • Dongol, B.1    Shah, Y.2    Kim, I.3    Gonzalez, F.J.4    Hunt, M.C.5
  • 17
    • 43249091827 scopus 로고    scopus 로고
    • Short- and medium-chain carnitine acyltransferases and acyl-CoA thioesterases in mouse provide complementary systems for transport of beta-oxidation products out of peroxisomes
    • Westin, M. A., Hunt, M. C., and Alexson, S. E. (2008) Short- and medium-chain carnitine acyltransferases and acyl-CoA thioesterases in mouse provide complementary systems for transport of beta-oxidation products out of peroxisomes. Cell. Mol. Life Sci. 65, 982-990
    • (2008) Cell. Mol. Life Sci. , vol.65 , pp. 982-990
    • Westin, M.A.1    Hunt, M.C.2    Alexson, S.E.3
  • 18
    • 34848817129 scopus 로고    scopus 로고
    • Peroxisomes contain a specific phytanoyl-CoA/pristanoyl-CoA thioesterase acting as a novel auxiliary enzyme in alpha- and beta-oxidation of methyl-branched fatty acids in mouse
    • DOI 10.1074/jbc.M703718200
    • Westin, M. A., Hunt, M. C., and Alexson, S. E. (2007) Peroxisomes contain a specific phytanoyl-CoA/pristanoyl-CoA thioesterase acting as a novel auxiliary enzyme in alpha- and beta-oxidation of methyl-branched fatty acids in mouse. J. Biol. Chem. 282, 26707-26716 (Pubitemid 47501944)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.37 , pp. 26707-26716
    • Westin, M.A.K.1    Hunt, M.C.2    Alexson, S.E.H.3
  • 19
    • 33644676983 scopus 로고    scopus 로고
    • The identification of a succinyl-CoA thioesterase suggests a novel pathway for succinate production in peroxisomes
    • DOI 10.1074/jbc.M508479200
    • Westin, M. A., Hunt, M. C., and Alexson, S. E. (2005) The identification of a succinyl-CoA thioesterase suggests a novel pathway for succinate production in peroxisomes. J. Biol. Chem. 280, 38125-38132 (Pubitemid 43853707)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.46 , pp. 38125-38132
    • Westin, M.A.K.1    Hunt, M.C.2    Alexson, S.E.H.3
  • 21
    • 0040960645 scopus 로고    scopus 로고
    • Molecular cloning and characterization of MT-ACT48, a novel mitochondrial acyl-CoA thioesterase
    • Poupon, V., Begue, B., Gagnon, J., Dautry-Varsat, A., Cerf- Bensussan, N., and Benmerah, A. (1999) Molecular cloning and characterization of MT-ACT48, a novel mitochondrial acyl-CoA thioesterase. J. Biol. Chem. 274, 19188-19194
    • (1999) J. Biol. Chem. , vol.274 , pp. 19188-19194
    • Poupon, V.1    Begue, B.2    Gagnon, J.3    Dautry-Varsat, A.4    Cerf-Bensussan, N.5    Benmerah, A.6
  • 22
    • 34249053821 scopus 로고    scopus 로고
    • Tissue subcellular fractionation and protein extraction for use in mass-spectrometry-based proteomics
    • DOI 10.1038/nprot.2006.273, PII NPROT.2006.273
    • Cox, B., and Emili, A. (2006) Tissue subcellular fractionation and protein extraction for use in mass-spectrometry-based proteomics. Nat. Protoc. 1, 1872-1878 (Pubitemid 46778056)
    • (2006) Nature Protocols , vol.1 , Issue.4 , pp. 1872-1878
    • Cox, B.1    Emili, A.2
  • 24
    • 77954261766 scopus 로고    scopus 로고
    • Identification of body fat mass as a major determinant of metabolic rate in mice
    • Kaiyala, K. J., Morton, G. J., Leroux, B. G., Ogimoto, K., Wisse, B., and Schwartz, M. W. (2010) Identification of body fat mass as a major determinant of metabolic rate in mice. Diabetes 59, 1657-1666
    • (2010) Diabetes , vol.59 , pp. 1657-1666
    • Kaiyala, K.J.1    Morton, G.J.2    Leroux, B.G.3    Ogimoto, K.4    Wisse, B.5    Schwartz, M.W.6
  • 25
    • 33750998524 scopus 로고    scopus 로고
    • Protection against Western diet-induced obesity and hepatic steatosis in liver fatty acid-binding protein knockout mice
    • DOI 10.1002/hep.21369
    • Newberry, E. P., Xie, Y., Kennedy, S. M., Luo, J., and Davidson, N. O. (2006) Protection against Western diet-induced obesity and hepatic steatosis in liver fatty acid-binding protein knockout mice. Hepatology 44, 1191-1205 (Pubitemid 44748370)
    • (2006) Hepatology , vol.44 , Issue.5 , pp. 1191-1205
    • Newberry, E.P.1    Xie, Y.2    Kennedy, S.M.3    Luo, J.4    Davidson, N.O.5
  • 27
    • 33750038561 scopus 로고    scopus 로고
    • Human thioesterase superfamily member 2 (hTHEM2) is co-localized with beta-tubulin onto the microtubule
    • DOI 10.1016/j.bbrc.2006.09.105, PII S0006291X06021309
    • Cheng, Z., Bao, S., Shan, X., Xu, H., and Gong, W. (2006) Human thioesterase superfamily member 2 (hTHEM2) is colocalized with beta-tubulin onto the microtubule. Biochem. Biophys. Res. Commun. 350, 850-853 (Pubitemid 44584172)
    • (2006) Biochemical and Biophysical Research Communications , vol.350 , Issue.4 , pp. 850-853
    • Cheng, Z.1    Bao, S.2    Shan, X.3    Xu, H.4    Gong, W.5
  • 29
    • 0033305213 scopus 로고    scopus 로고
    • Peroxisome proliferatoractivated receptors: Nuclear control of metabolism
    • Desvergne, B., and Wahli, W. (1999) Peroxisome proliferatoractivated receptors: nuclear control of metabolism. Endocr. Rev. 20, 649 - 688
    • (1999) Endocr. Rev. , vol.20 , pp. 649-688
    • Desvergne, B.1    Wahli, W.2
  • 30
    • 77954309627 scopus 로고    scopus 로고
    • PC-TP/ StARD2: Of membranes and metabolism
    • Kang, H. W., Wei, J., and Cohen, D. E. (2010) PC-TP/ StARD2: Of membranes and metabolism. Trends Endocrinol. Metab. 21, 449 - 456
    • (2010) Trends Endocrinol. Metab. , vol.21 , pp. 449-456
    • Kang, H.W.1    Wei, J.2    Cohen, D.E.3
  • 31
    • 33748657539 scopus 로고    scopus 로고
    • Analysis of the mouse and human acyl-CoA thioesterase (ACOT) gene clusters shows that convergent, functional evolution results in a reduced number of human peroxisomal ACOTs
    • DOI 10.1096/fj.06-6042com
    • Hunt, M. C., Rautanen, A., Westin, M. A., Svensson, L. T., and Alexson, S. E. (2006) Analysis of the mouse and human acyl-CoA thioesterase (ACOT) gene clusters shows that convergent, functional evolution results in a reduced number of human peroxisomal ACOTs. FASEB J. 20, 1855-1864 (Pubitemid 44933799)
    • (2006) FASEB Journal , vol.20 , Issue.11 , pp. 1855-1864
    • Hunt, M.C.1    Rautanen, A.2    Westin, M.A.K.3    Svensson, L.T.4    Alexson, S.E.H.5
  • 32
    • 0033607684 scopus 로고    scopus 로고
    • Peroxisome proliferator-induced long chain acyl-CoA thioesterases comprise a highly conserved novel multi-gene family involved in lipid metabolism
    • Hunt, M. C., Nousiainen, S. E., Huttunen, M. K., Orii, K. E., Svensson, L. T., and Alexson, S. E. (1999) Peroxisome proliferator-induced long chain acyl-CoA thioesterases comprise a highly conserved novel multi-gene family involved in lipid metabolism. J. Biol. Chem. 274, 34317-34326 (Pubitemid 129511774)
    • (1999) Journal of Biological Chemistry , vol.274 , Issue.48 , pp. 34317-34326
    • Hunt, M.C.1    Nousiainen, S.E.B.2    Huttunen, M.K.3    Orii, K.E.4    Svensson, L.T.5    Alexson, S.E.H.6
  • 33
    • 1542283630 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor alpha target genes
    • DOI 10.1007/s00018-003-3216-3
    • Mandard, S., Muller, M., and Kersten, S. (2004) Peroxisome proliferator-activated receptor alpha target genes. Cell. Mol. Life Sci. 61, 393-416 (Pubitemid 38316578)
    • (2004) Cellular and Molecular Life Sciences , vol.61 , Issue.4 , pp. 393-416
    • Mandard, S.1    Muller, M.2    Kersten, S.3
  • 34
    • 80053450975 scopus 로고    scopus 로고
    • The emerging roles of fatty acid translocase/CD36 and the aryl hydrocarbon receptor in fatty liver disease
    • He, J., Lee, J. H., Febbraio, M., and Xie, W. (2011) The emerging roles of fatty acid translocase/CD36 and the aryl hydrocarbon receptor in fatty liver disease. Exp. Biol. Med. 236, 1116-1121
    • (2011) Exp. Biol. Med. , vol.236 , pp. 1116-1121
    • He, J.1    Lee, J.H.2    Febbraio, M.3    Xie, W.4
  • 35
    • 63749108094 scopus 로고    scopus 로고
    • Cellular fatty acid uptake: A pathway under construction
    • Su, X., and Abumrad, N. A. (2009) Cellular fatty acid uptake: a pathway under construction. Trends Endocrinol. Metab. 20, 72-77
    • (2009) Trends Endocrinol. Metab. , vol.20 , pp. 72-77
    • Su, X.1    Abumrad, N.A.2
  • 37
    • 74049108945 scopus 로고    scopus 로고
    • Fibroblast growth factor 21: From pharmacology to physiology
    • Kliewer, S. A., and Mangelsdorf, D. J. (2010) Fibroblast growth factor 21: from pharmacology to physiology. Am. J. Clin. Nutr. 91, 254S-257S
    • (2010) Am. J. Clin. Nutr. , vol.91
    • Kliewer, S.A.1    Mangelsdorf, D.J.2
  • 38
    • 79952036479 scopus 로고    scopus 로고
    • Fatty acid regulation of hepatic lipid metabolism
    • Jump, D. B. (2011) Fatty acid regulation of hepatic lipid metabolism. Curr. Opin. Clin. Nutr. Metab. Care 14, 115-120
    • (2011) Curr. Opin. Clin. Nutr. Metab. Care , vol.14 , pp. 115-120
    • Jump, D.B.1
  • 39
    • 79251557845 scopus 로고    scopus 로고
    • Targeting Forkhead box O1 from the concept to metabolic diseases: Lessons from mouse models
    • Cheng, Z., and White, M. F. (2011) Targeting Forkhead box O1 from the concept to metabolic diseases: lessons from mouse models. Antioxid. Redox Signal. 14, 649-661
    • (2011) Antioxid. Redox Signal. , vol.14 , pp. 649-661
    • Cheng, Z.1    White, M.F.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.