A polymorphism in New Zealand inbred mouse strains that inactivates phosphatidylcholine transfer protein

FEBS Letters

Volumn 580, Issue 25, 2006, Pages 5953-5958

  Pan, Huei Ju ^a   Agate, Diana S ^b   King, Benjamin L ^c   Wu, Michele K ^d   Roderick, Steven L ^b   Leiter, Edward H ^c   Cohen, David E ^d  

^a INSTITUTE OF BIOMEDICAL SCIENCES   (Taiwan)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^c JACKSON LABORATORY   (United States)

^d BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Diabetes; Obesity; Protein structure; Quantitative trait locus; START domain

Indexed keywords

ARGININE; CARRIER PROTEIN; HISTIDINE; LECITHIN TRANSFER PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIABETIC OBESITY; DIABETOGENESIS; GENE INACTIVATION; GENE LOCUS; GENE SEGREGATION; GENETIC POLYMORPHISM; INBRED STRAIN; MOUSE; MOUSE STRAIN; MULTIFACTORIAL INHERITANCE; NONHUMAN; POINT MUTATION; PREDICTION; PRIORITY JOURNAL; PROTEIN LOCALIZATION; QUANTITATIVE TRAIT LOCUS; RECESSIVE GENE; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; STRUCTURE ANALYSIS;

AMINO ACID SUBSTITUTION; ANIMALS; BASE SEQUENCE; CHROMOSOME MAPPING; DNA, COMPLEMENTARY; MALE; MICE; MICE, INBRED NZB; MICE, INBRED STRAINS; MICE, OBESE; MODELS, MOLECULAR; PHOSPHATIDYLCHOLINES; PHOSPHOLIPID TRANSFER PROTEINS; POINT MUTATION; POLYMORPHISM, GENETIC; PROTEIN CONFORMATION; SPECIES SPECIFICITY;

EID: 33751015133     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2006.09.066     Document Type: Article

References (30)

1. Leiter E.H., Reifsnyder P.C., Flurkey K., Partke H.J., Junger E., and Herberg L. NIDDM genes in mice: deleterious synergism by both parental genomes contributes to diabetogenic thresholds. Diabetes 47 (1998) 1287-1295
2. Watkins S.M., Reifsnyder P.R., Pan H.J., German J.B., and Leiter E.H. Lipid metabolome-wide effects of the PPARgamma agonist rosiglitazone. J. Lipid Res. 43 (2002) 1809-1817
3. Pan H.J., Reifsnyder P., Vance D.E., Xiao Q., and Leiter E.H. Pharmacogenetic analysis of rosiglitazone-induced hepatosteatosis in new mouse models of type 2 diabetes. Diabetes 54 (2005) 1854-1862
4. Pan H.J., Lin Y., Chen Y.E., Vance D.E., and Leiter E.H. Adverse hepatic and cardiac responses to rosiglitazone in a new mouse model of type 2 diabetes: relation to dysregulated phosphatidylcholine metabolism. Vascul. Pharmacol. 45 (2006) 65-71
5. Wirtz K.W. Phospholipid transfer proteins. Annu. Rev. Biochem. 60 (1991) 73-99
6. van Helvoort A., et al. Mice without phosphatidylcholine transfer protein have no defects in the secretion of phosphatidylcholine into bile or into lung airspaces. Proc. Natl. Acad. Sci. USA 96 (1999) 11501-11506
7. Wu M.K., and Cohen D.E. Phosphatidylcholine transfer protein regulates size and hepatic uptake of high-density lipoproteins. Am. J. Physiol. 289 (2005) G1067-G1074
8. Wu M.K., and Cohen D.E. Altered hepatic cholesterol metabolism compensates for disruption of phosphatidylcholine transfer protein in mice. Am. J. Physiol. 289 (2005) G456-G461
9. Wu M.K., Hyogo H., Yadav S., Novikoff P.M., and Cohen D.E. Impaired response of biliary lipid secretion to a lithogenic diet in phosphatidylcholine transfer protein-deficient mice. J. Lipid Res. 46 (2005) 422-431
10. Shoda J., et al. Etiologic significance of defects in cholesterol, phospholipid, and bile acid metabolism in the liver of patients with intrahepatic calculi. Hepatology 33 (2001) 1194-1205
11. Feng L., Chan W.W., Roderick S.L., and Cohen D.E. High-level expression and mutagenesis of recombinant human phosphatidylcholine transfer protein using a synthetic gene: evidence for a C-terminal membrane binding domain. Biochemistry 39 (2000) 15399-15409
12. Thompson J.D., Higgins D.G., and Gibson T.J. CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res. 22 (1994) 4673-4680
13. Cuff J.A., Clamp M.E., Siddiqui A.S., Finlay M., and Barton G.J. JPred: a consensus secondary structure prediction server. Bioinformatics 14 (1998) 892-893
14. Jones T.A., Zou J.-Y., Cowan S.W., and Kjeldgaard M. Improved methods for building protein models in electron density maps and the location of errors in these models. Acta Crystallogr. A 47 (1991) 110-119
15. Feng L., and Cohen D.E. Baculovirus-mediated expression of recombinant rat phosphatidylcholine transfer protein. J. Lipid Res. 39 (1998) 1862-1869
16. Roderick S.L., Chan W.W., Agate D.S., Olsen L.R., Vetting M.W., Rajashankar K.R., and Cohen D.E. Structure of human phosphatidylcholine transfer protein in complex with its ligand. Nat. Struct. Biol. 9 (2002) 507-511
17. Wu M.K., Boylan M.O., and Cohen D.E. Cloning and gene structure of rat phosphatidylcholine transfer protein, Pctp. Gene 235 (1999) 111-120
18. DeLano W.L. The PyMOL User's Manual (2002), DeLano Scientific, San Carlos, CA
19. Reifsnyder P.C., and Leiter E.H. Deconstructing and reconstructing obesity-induced diabetes (diabesity) in mice. Diabetes 51 (2002) 825-832
20. Ponting C.P., and Aravind L. START: a lipid-binding domain in StAR, HD-ZIP and signalling proteins. Trends Biochem. Sci. 24 (1999) 130-132
21. Tsujishita Y., and Hurley J.H. Structure and lipid transport mechanism of a StAR-related domain. Nat. Struct. Biol. 7 (2000) 408-414
22. Soccio R.E., and Breslow J.L. StAR-related lipid transfer (START) proteins: mediators of intracellular lipid metabolism. J. Biol. Chem. 278 (2003) 22183-22186
23. Geijtenbeek T.B.H., Smith A.J., Borst P., and Wirtz K.W.A. cDNA cloning and tissue specific expression of the phosphatidylcholine transfer protein gene. Biochem. J. 316 (1996) 49-55
24. Cohen D.E., Green R.M., Wu M.K., and Beier D.R. Cloning, tissue-specific expression, gene structure and chromosomal localization of human phosphatidylcholine transfer protein. Biochim. Biophys. Acta 1447 (1999) 265-270
25. Baez J.M., Barbour S.E., and Cohen D.E. Phosphatidylcholine transfer protein promotes apolipoprotein A-I-mediated lipid efflux in Chinese hamster ovary cells. J. Biol. Chem. 277 (2002) 6198-6206
26. Baez J.M., Tabas I., and Cohen D.E. Decreased lipid efflux and increased susceptibility to cholesterol-induced apoptosis in macrophages lacking phosphatidylcholine transfer protein. Biochem. J. 388 (2005) 57-63
27. Wirtz K.W. Phospholipid transfer proteins in perspective. FEBS Lett. 580 (2006) 5436-5441
28. DiCorleto P.E., and Zilversmit D.B. Protein-catalyzed exchange of phosphatidylcholine between sonicated liposomes and multilamellar vesicles. Biochemistry 16 (1977) 2145-2150
29. Bielschowsky M., and Goodall C.M. Origin of inbred NZ mouse strains. Cancer Res. 30 (1970) 834-836
30. Festing M.F.W. Origins and characteristics of inbred strains of mice. In: Lyon M.F., Rastan S., and Brown S.D.M. (Eds). Genetic Variants and Strains of the Laboratory Mouse (1996), Oxford University Press, Oxford 1537-1576