Simultaneous determination by LC-MS/MS of 25-methoxydammarane-3β, 12β,20-triol epimers and active metabolites in rat plasma after intravenous administration

Xenobiotica

Volumn 43, Issue 10, 2013, Pages 868-874

  Shi, Cai Hong ^a   Zhang, Xiangrong ^a   Suo, Hao ^a   Yin, Tian ^a   Xu, Haiyan ^a   Yuan, Bo ^a   Zhao, Yuqing ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

12 ; 20 triol; 25 Methoxydammarane 3 ; 25 OH PPD; Active metabolite; Epimer; Pharmacokinetics; UPLC MS MS

Indexed keywords

25 METHOXYDAMMARANE 3BETA 12BETA 20 TRIOL; DRUG METABOLITE; SAPOGENIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG HALF LIFE; DRUG SCREENING; DRUG STRUCTURE; EPIMER; FEMALE; MALE; MASS SPECTROMETRY; NONHUMAN; PANAX NOTOGINSENG; PLASMA CLEARANCE; PLASMA CONCENTRATION-TIME CURVE; RAT; STEREOCHEMISTRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

ADMINISTRATION, INTRAVENOUS; ANIMALS; AREA UNDER CURVE; CHROMATOGRAPHY, LIQUID; FEMALE; HALF-LIFE; MALE; RATS; RATS, WISTAR; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; STEREOISOMERISM; TANDEM MASS SPECTROMETRY; TRITERPENES;

EID: 84884221754     PISSN: 00498254     EISSN: 13665928     Source Type: Journal    
DOI: 10.3109/00498254.2013.789149     Document Type: Article

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