Selective inhibition of phosphodiesterase 5 enhances glutamatergic synaptic plasticity and memory in mice

Synapse

Volumn 67, Issue 11, 2013, Pages 741-747

  Uthayathas, Subramaniam ^a,b   Parameshwaran, Kodeeswaran ^a,c   Karuppagounder, Senthilkumar S ^a,d   Ahuja, Manuj ^a   Dhanasekaran, Muralikrishnan ^a   Suppiramaniam, Vishnu ^a  

^a AUBURN UNIVERSITY   (United States)

^b HOWARD UNIVERSITY COLLEGE OF MEDICINE   (United States)

^c AUBURN UNIVERSITY   (United States)

^d JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Hippocampus; Memory; Phosphodiesterases; Sildenafil; Synaptic plasticity

Indexed keywords

GLUTAMIC ACID; PHOSPHODIESTERASE V; SILDENAFIL;

ACUTE DRUG ADMINISTRATION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN REGION; CONTROLLED STUDY; ENZYME INHIBITION; HIPPOCAMPUS; IN VIVO STUDY; LONG TERM POTENTIATION; MALE; MEMORY CONSOLIDATION; MENTAL PERFORMANCE; MENTAL TASK; MOUSE; NERVE CELL PLASTICITY; NEUROMODULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECOGNITION; SPATIAL MEMORY; SYNAPTIC TRANSMISSION; TASK PERFORMANCE;

HIPPOCAMPUS; MEMORY; PHOSPHODIESTERASES; SILDENAFIL; SYNAPTIC PLASTICITY;

ANIMALS; EXCITATORY POSTSYNAPTIC POTENTIALS; HIPPOCAMPUS; LONG-TERM POTENTIATION; MAZE LEARNING; MEMORY; MICE; MICE, INBRED C57BL; NEURONS; PHOSPHODIESTERASE 5 INHIBITORS; PIPERAZINES; PURINES; SULFONES;

EID: 84884211273     PISSN: 08874476     EISSN: 10982396     Source Type: Journal    
DOI: 10.1002/syn.21676     Document Type: Article

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