메뉴 건너뛰기




Volumn 756, Issue 1-2, 2013, Pages 86-94

Radiation response of chemically derived mitochondrial DNA-deficient AG01522 human primary fibroblasts

Author keywords

Cytogenetic damage; Human primary fibroblasts; Ionizing radiations; Mitochondria; Mitochondrial fragmentation; ROS

Indexed keywords

CYTOCHROME C OXIDASE; REACTIVE OXYGEN METABOLITE; ZALCITABINE;

EID: 84884202987     PISSN: 13835718     EISSN: 18793592     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2013.05.010     Document Type: Article
Times cited : (3)

References (46)
  • 1
    • 0000004493 scopus 로고    scopus 로고
    • Expression of mtDNA and nDNA encoded respiratory chain proteins in chemically and genetically derived Rho0 human fibroblasts: a comparison of subunit proteins in normal fibroblasts treated with ethidium bromide and fibroblasts from a patient with mtDNA depletion syndrome
    • Marusich M.F., Robinson B.H., Taanman J.W., Kim S.J., Schillace R., Smith J.L., Capaldi R.A. Expression of mtDNA and nDNA encoded respiratory chain proteins in chemically and genetically derived Rho0 human fibroblasts: a comparison of subunit proteins in normal fibroblasts treated with ethidium bromide and fibroblasts from a patient with mtDNA depletion syndrome. Biochim. Biophys. Acta 1997, 1362:145-159.
    • (1997) Biochim. Biophys. Acta , vol.1362 , pp. 145-159
    • Marusich, M.F.1    Robinson, B.H.2    Taanman, J.W.3    Kim, S.J.4    Schillace, R.5    Smith, J.L.6    Capaldi, R.A.7
  • 2
    • 63549146637 scopus 로고    scopus 로고
    • Mitochondrial mutant cells are hypersensitive to ionizing radiation, phleomycin and mitomycin C
    • Kulkarni R., Reither A., Thomas R.A., Tucker J.D. Mitochondrial mutant cells are hypersensitive to ionizing radiation, phleomycin and mitomycin C. Mutat. Res. 2009, 663:46-51.
    • (2009) Mutat. Res. , vol.663 , pp. 46-51
    • Kulkarni, R.1    Reither, A.2    Thomas, R.A.3    Tucker, J.D.4
  • 3
    • 0032575752 scopus 로고    scopus 로고
    • Mitochondria and apoptosis
    • Green D.R., Reed J.C. Mitochondria and apoptosis. Science 1998, 281:1309-1312.
    • (1998) Science , vol.281 , pp. 1309-1312
    • Green, D.R.1    Reed, J.C.2
  • 4
    • 0028841135 scopus 로고
    • Ischemia reperfusion injury in tumors: the role of oxygen radicals and nitric oxide
    • Parkins C.S., Dennis M.F., Stratford M.R., Hill S.A., Chaplin D.J. Ischemia reperfusion injury in tumors: the role of oxygen radicals and nitric oxide. Cancer Res. 1995, 55:6026-6029.
    • (1995) Cancer Res. , vol.55 , pp. 6026-6029
    • Parkins, C.S.1    Dennis, M.F.2    Stratford, M.R.3    Hill, S.A.4    Chaplin, D.J.5
  • 5
    • 0036015519 scopus 로고    scopus 로고
    • Exposure to low-level chemicals and ionizing radiation: reactive oxygen species and cellular pathways
    • Lehnert B.E., Iyer R. Exposure to low-level chemicals and ionizing radiation: reactive oxygen species and cellular pathways. Hum. Exp. Toxicol. 2002, 21:65-69.
    • (2002) Hum. Exp. Toxicol. , vol.21 , pp. 65-69
    • Lehnert, B.E.1    Iyer, R.2
  • 6
    • 0025394579 scopus 로고
    • New trends in photobiology. The interaction of UVA radiation with cultured cells
    • Tyrrell R.M., Keyse S.M. New trends in photobiology. The interaction of UVA radiation with cultured cells. J. Photochem. Photobiol. B 1990, 4:349-361.
    • (1990) J. Photochem. Photobiol. B , vol.4 , pp. 349-361
    • Tyrrell, R.M.1    Keyse, S.M.2
  • 7
    • 0017810263 scopus 로고
    • Do mitochondria produce oxygen radicals in vivo?
    • Nohl H., Hegner D. Do mitochondria produce oxygen radicals in vivo?. Eur. J. Biochem. 1978, 82:563-567.
    • (1978) Eur. J. Biochem. , vol.82 , pp. 563-567
    • Nohl, H.1    Hegner, D.2
  • 8
    • 0023811053 scopus 로고
    • Normal oxidative damage to mitochondrial and nuclear DNA is extensive
    • Richter C., Park J.W., Ames B.N. Normal oxidative damage to mitochondrial and nuclear DNA is extensive. Proc. Natl. Acad. Sci. U.S.A. 1988, 85:6465-6467.
    • (1988) Proc. Natl. Acad. Sci. U.S.A. , vol.85 , pp. 6465-6467
    • Richter, C.1    Park, J.W.2    Ames, B.N.3
  • 9
    • 0038730829 scopus 로고    scopus 로고
    • Radiation-induced versus endogenous DNA damage: possible effect of inducible protective responses in mitigating endogenous damage
    • Pollycove M., Feinendegen L.E. Radiation-induced versus endogenous DNA damage: possible effect of inducible protective responses in mitigating endogenous damage. Hum. Exp. Toxicol. 2003, 22:290-306.
    • (2003) Hum. Exp. Toxicol. , vol.22 , pp. 290-306
    • Pollycove, M.1    Feinendegen, L.E.2
  • 10
    • 1842612108 scopus 로고    scopus 로고
    • Mitochondrial oxidative stress causes chromosomal instability of mouse embryonic fibroblasts
    • Samper E., Nicholls D.G., Melov S. Mitochondrial oxidative stress causes chromosomal instability of mouse embryonic fibroblasts. Aging Cell 2003, 2:277-285.
    • (2003) Aging Cell , vol.2 , pp. 277-285
    • Samper, E.1    Nicholls, D.G.2    Melov, S.3
  • 11
    • 84855217118 scopus 로고    scopus 로고
    • Mitochondria sentencing about cellular life and death: a matter of oxidative stress
    • Apostolova N., Blas-Garcia A., Esplugues J.V. Mitochondria sentencing about cellular life and death: a matter of oxidative stress. Curr. Pharm. Des. 2011, 17:4047-4060.
    • (2011) Curr. Pharm. Des. , vol.17 , pp. 4047-4060
    • Apostolova, N.1    Blas-Garcia, A.2    Esplugues, J.V.3
  • 12
    • 3242696917 scopus 로고    scopus 로고
    • Mechanism of telomere shortening by oxidative stress
    • Kawanishi S., Oikawa S. Mechanism of telomere shortening by oxidative stress. Ann. N. Y. Acad. Sci. 2004, 1019:278-284.
    • (2004) Ann. N. Y. Acad. Sci. , vol.1019 , pp. 278-284
    • Kawanishi, S.1    Oikawa, S.2
  • 13
    • 0035872421 scopus 로고    scopus 로고
    • Ionizing radiation-induced, mitochondria-dependent generation of reactive oxygen/nitrogen
    • Leach J.K., Van Tuyle G., Lin P.S., Schmidt-Ullrich R., Mikkelsen R.B. Ionizing radiation-induced, mitochondria-dependent generation of reactive oxygen/nitrogen. Cancer Res. 2001, 61:3894-3901.
    • (2001) Cancer Res. , vol.61 , pp. 3894-3901
    • Leach, J.K.1    Van Tuyle, G.2    Lin, P.S.3    Schmidt-Ullrich, R.4    Mikkelsen, R.B.5
  • 14
    • 6344264980 scopus 로고    scopus 로고
    • Increases in oxidative stress in the progeny of X-irradiated cells
    • Rugo R.E., Schiestl R.H. Increases in oxidative stress in the progeny of X-irradiated cells. Radiat. Res. 2004, 162:416-425.
    • (2004) Radiat. Res. , vol.162 , pp. 416-425
    • Rugo, R.E.1    Schiestl, R.H.2
  • 15
    • 33750633422 scopus 로고    scopus 로고
    • A role for mitochondrial dysfunction in perpetuating radiation-induced genomic instability
    • Kim G.J., Fiskum G.M., Morgan W.F. A role for mitochondrial dysfunction in perpetuating radiation-induced genomic instability. Cancer Res. 2006, 66:10377-10383.
    • (2006) Cancer Res. , vol.66 , pp. 10377-10383
    • Kim, G.J.1    Fiskum, G.M.2    Morgan, W.F.3
  • 16
    • 34250879092 scopus 로고    scopus 로고
    • Cytoplasmic irradiation induces mitochondrial-dependent 53BP1 protein relocalization in irradiated and bystander cells
    • Tartier L., Gilchrist S., Burdak-Rothkamm S., Folkard M., Prise K.M. Cytoplasmic irradiation induces mitochondrial-dependent 53BP1 protein relocalization in irradiated and bystander cells. Cancer Res. 2007, 67:5872-5879.
    • (2007) Cancer Res. , vol.67 , pp. 5872-5879
    • Tartier, L.1    Gilchrist, S.2    Burdak-Rothkamm, S.3    Folkard, M.4    Prise, K.M.5
  • 21
    • 0031662510 scopus 로고    scopus 로고
    • A simple method for simultaneous interphase-metaphase chromosome analysis in biodosimetry
    • Durante M., Furusawa Y., Gotoh E. A simple method for simultaneous interphase-metaphase chromosome analysis in biodosimetry. Int. J. Radiat. Biol. 1998, 74:457-462.
    • (1998) Int. J. Radiat. Biol. , vol.74 , pp. 457-462
    • Durante, M.1    Furusawa, Y.2    Gotoh, E.3
  • 23
    • 0035023004 scopus 로고    scopus 로고
    • Analyzing radiation-induced complex chromosome rearrangements by combinatorial painting
    • Cornforth M.N. Analyzing radiation-induced complex chromosome rearrangements by combinatorial painting. Radiat. Res. 2001, 155:643-659.
    • (2001) Radiat. Res. , vol.155 , pp. 643-659
    • Cornforth, M.N.1
  • 24
    • 84866680950 scopus 로고    scopus 로고
    • Differences in phosphorylated histone H2AX foci formation and removal of cells exposed to low and high linear energy transfer radiation
    • Schmid T.E., Zlobinskaya O., Multhoff G. Differences in phosphorylated histone H2AX foci formation and removal of cells exposed to low and high linear energy transfer radiation. Curr. Genomics 2012, 13:418-425.
    • (2012) Curr. Genomics , vol.13 , pp. 418-425
    • Schmid, T.E.1    Zlobinskaya, O.2    Multhoff, G.3
  • 25
    • 0029877507 scopus 로고    scopus 로고
    • Use of ethidium bromide to manipulate ratio of mutated and wild-type mitochondrial DNA in cultured cells
    • King M.P. Use of ethidium bromide to manipulate ratio of mutated and wild-type mitochondrial DNA in cultured cells. Methods Enzymol. 1996, 264:339-344.
    • (1996) Methods Enzymol. , vol.264 , pp. 339-344
    • King, M.P.1
  • 26
    • 3242754267 scopus 로고    scopus 로고
    • Rapid analysis of mitochondrial DNA depletion by fluorescence in situ hybridization and immunocytochemistry: potential strategies for HIV therapeutic monitoring
    • Janes M.S., Hanson B.J., Hill D.M., Buller G.M., Agnew J.Y., Sherwood S.W., Cox W.G., Yamagata K., Capaldi R.A. Rapid analysis of mitochondrial DNA depletion by fluorescence in situ hybridization and immunocytochemistry: potential strategies for HIV therapeutic monitoring. J. Histochem. Cytochem. 2004, 52:1011-1018.
    • (2004) J. Histochem. Cytochem. , vol.52 , pp. 1011-1018
    • Janes, M.S.1    Hanson, B.J.2    Hill, D.M.3    Buller, G.M.4    Agnew, J.Y.5    Sherwood, S.W.6    Cox, W.G.7    Yamagata, K.8    Capaldi, R.A.9
  • 28
    • 0031034761 scopus 로고    scopus 로고
    • Overexpression of DNA polymerase beta sensitizes mammalian cells to 2',3'-deoxycytidine and 3'-azido-3'-deoxythymidine
    • Bouayadi K., Hoffmann J.S., Fons P., Tiraby M., Reynes J.P., Cazaux C. Overexpression of DNA polymerase beta sensitizes mammalian cells to 2',3'-deoxycytidine and 3'-azido-3'-deoxythymidine. Cancer Res. 1997, 57:110-116.
    • (1997) Cancer Res. , vol.57 , pp. 110-116
    • Bouayadi, K.1    Hoffmann, J.S.2    Fons, P.3    Tiraby, M.4    Reynes, J.P.5    Cazaux, C.6
  • 29
    • 0038331337 scopus 로고    scopus 로고
    • Mitochondrial dysfunction leads to telomere attrition and genomic instability
    • Liu L., Trimarchi J.R., Smith P.J., Keefe D.L. Mitochondrial dysfunction leads to telomere attrition and genomic instability. Aging Cell 2002, 1:40-46.
    • (2002) Aging Cell , vol.1 , pp. 40-46
    • Liu, L.1    Trimarchi, J.R.2    Smith, P.J.3    Keefe, D.L.4
  • 30
    • 49549101624 scopus 로고    scopus 로고
    • Partial depletion of mitochondrial DNA from human skin fibroblasts induces a gene expression profile reminiscent of photoaged skin
    • Schroeder P., Gremmel T., Berneburg M., Krutmann J. Partial depletion of mitochondrial DNA from human skin fibroblasts induces a gene expression profile reminiscent of photoaged skin. J. Invest. Dermatol. 2008, 128:2297-2303.
    • (2008) J. Invest. Dermatol. , vol.128 , pp. 2297-2303
    • Schroeder, P.1    Gremmel, T.2    Berneburg, M.3    Krutmann, J.4
  • 31
    • 24044471309 scopus 로고    scopus 로고
    • Superoxide dismutases and their impact upon human health
    • Johnson F., Giulivi C. Superoxide dismutases and their impact upon human health. Mol. Aspects Med. 2005, 26:340-352.
    • (2005) Mol. Aspects Med. , vol.26 , pp. 340-352
    • Johnson, F.1    Giulivi, C.2
  • 33
    • 0032574770 scopus 로고    scopus 로고
    • Activation of apurinic/apyrimidinic endonuclease in human cells by reactive oxygen species and its correlation with their adaptive response to genotoxicity of free radicals
    • Ramana C.V., Boldogh I., Izumi T., Mitra S. Activation of apurinic/apyrimidinic endonuclease in human cells by reactive oxygen species and its correlation with their adaptive response to genotoxicity of free radicals. Proc. Natl. Acad. Sci. U.S.A. 1998, 95:5061-5066.
    • (1998) Proc. Natl. Acad. Sci. U.S.A. , vol.95 , pp. 5061-5066
    • Ramana, C.V.1    Boldogh, I.2    Izumi, T.3    Mitra, S.4
  • 34
    • 84867483822 scopus 로고    scopus 로고
    • Ionizing radiation-induced metabolic oxidative stress and prolonged cell injury
    • Azzam E.I., Jay-Gerin J.P., Pain D. Ionizing radiation-induced metabolic oxidative stress and prolonged cell injury. Cancer Lett. 2012, 327:48-60.
    • (2012) Cancer Lett. , vol.327 , pp. 48-60
    • Azzam, E.I.1    Jay-Gerin, J.P.2    Pain, D.3
  • 36
    • 59649090271 scopus 로고    scopus 로고
    • Mechanisms of telomeric instability
    • Baird D.M. Mechanisms of telomeric instability. Cytogenet. Genome Res. 2008, 122:308-314.
    • (2008) Cytogenet. Genome Res. , vol.122 , pp. 308-314
    • Baird, D.M.1
  • 38
    • 0032489520 scopus 로고    scopus 로고
    • DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139
    • Rogakou E.P., Pilch D.R., Orr A.H., Ivanova V.S., Bonner W.M. DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139. J. Biol. Chem. 1998, 273:5858-5868.
    • (1998) J. Biol. Chem. , vol.273 , pp. 5858-5868
    • Rogakou, E.P.1    Pilch, D.R.2    Orr, A.H.3    Ivanova, V.S.4    Bonner, W.M.5
  • 39
    • 0027278557 scopus 로고
    • Instability and decay of the primary structure of DNA
    • Lindahl T. Instability and decay of the primary structure of DNA. Nature 1993, 362:709-715.
    • (1993) Nature , vol.362 , pp. 709-715
    • Lindahl, T.1
  • 40
    • 46249133363 scopus 로고    scopus 로고
    • Hydrogen peroxide mediates the radiation-induced mutator phenotype in mammalian cells
    • Dayal D., Martin S.M., Limoli C.L., Spitz D.R. Hydrogen peroxide mediates the radiation-induced mutator phenotype in mammalian cells. Biochem. J. 2008, 413:185-191.
    • (2008) Biochem. J. , vol.413 , pp. 185-191
    • Dayal, D.1    Martin, S.M.2    Limoli, C.L.3    Spitz, D.R.4
  • 41
    • 33750616552 scopus 로고    scopus 로고
    • Mitochondrial dysfunction, persistently elevated levels of reactive oxygen species and radiation-induced genomic instability: a review
    • Kim G.J., Chandrasekaran K., Morgan W.F. Mitochondrial dysfunction, persistently elevated levels of reactive oxygen species and radiation-induced genomic instability: a review. Mutagenesis 2006, 21:361-367.
    • (2006) Mutagenesis , vol.21 , pp. 361-367
    • Kim, G.J.1    Chandrasekaran, K.2    Morgan, W.F.3
  • 43
    • 0030761388 scopus 로고    scopus 로고
    • Dihydroorotat-ubiquinone oxidoreductase links mitochondria in the biosynthesis of pyrimidine nucleotides
    • Loffler M., Jockel J., Schuster G., Becker C. Dihydroorotat-ubiquinone oxidoreductase links mitochondria in the biosynthesis of pyrimidine nucleotides. Mol. Cell. Biochem. 1997, 174:125-129.
    • (1997) Mol. Cell. Biochem. , vol.174 , pp. 125-129
    • Loffler, M.1    Jockel, J.2    Schuster, G.3    Becker, C.4
  • 44
    • 0032860818 scopus 로고    scopus 로고
    • Uracil misincorporation, DNA strand breaks, and gene amplification are associated with tumorigenic cell transformation in folate deficient/repleted Chinese hamster ovary cells
    • Melnyk S., Pogribna M., Miller B.J., Basnakian A.G., Pogribny I.P., James S.J. Uracil misincorporation, DNA strand breaks, and gene amplification are associated with tumorigenic cell transformation in folate deficient/repleted Chinese hamster ovary cells. Cancer Lett. 1999, 146:35-44.
    • (1999) Cancer Lett. , vol.146 , pp. 35-44
    • Melnyk, S.1    Pogribna, M.2    Miller, B.J.3    Basnakian, A.G.4    Pogribny, I.P.5    James, S.J.6
  • 46
    • 0036015523 scopus 로고    scopus 로고
    • Reactive oxygen species in cell responses to toxic agents
    • Feinendegen L.E. Reactive oxygen species in cell responses to toxic agents. Hum. Exp. Toxicol. 2002, 21:85-90.
    • (2002) Hum. Exp. Toxicol. , vol.21 , pp. 85-90
    • Feinendegen, L.E.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.