Mimicry of high-density lipoprotein: Functional peptide-lipid nanoparticles based on multivalent peptide constructs

Journal of the American Chemical Society

Volumn 135, Issue 36, 2013, Pages 13414-13424

  Zhao, Yannan ^a   Imura, Tomohiro ^a   Leman, Luke J ^a   Curtiss, Linda K ^a   Maryanoff, Bruce E ^a   Ghadiri, M Reza ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANALYTICAL ULTRACENTRIFUGE; APOLIPOPROTEIN A-I (APOA-I); BIOPHYSICAL TECHNIQUES; CELLULAR CHOLESTEROL EFFLUX; CHOLESTEROL TRANSPORT; ENZYMATIC DIGESTIONS; HIGH-DENSITY LIPOPROTEINS; PHARMACOKINETIC PROFILES;

BIOMIMETICS; CHOLESTEROL; DISEASES; ENZYME INHIBITION; FLUORESCENCE SPECTROSCOPY; LIPOPROTEINS; MAMMALS; NANOPARTICLES; PHOSPHOLIPIDS; TRANSMISSION ELECTRON MICROSCOPY;

PEPTIDES;

APOLIPOPROTEIN A1; HIGH DENSITY LIPOPROTEIN; NANOPARTICLE; PEPTIDE LIPID NANOPARTICLE; PHOSPHOLIPID; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL TRANSPORT; CIRCULAR DICHROISM; CONTROLLED STUDY; ELECTRON MICROSCOPY; ENZYMATIC DEGRADATION; FLUORESCENCE SPECTROSCOPY; GEL PERMEATION CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; IN VITRO STUDY; IN VIVO STUDY; KIDNEY CLEARANCE; LIPID MEMBRANE; MACROPHAGE; MALE; MOLECULAR MIMICRY; MOUSE; NONHUMAN; PEPTIDE SYNTHESIS; PHOSPHOLIPID BILAYER; PLASMA HALF LIFE; PROTEIN ENGINEERING; PROTEIN STRUCTURE; SEDIMENTATION; SURFACE TENSION; TRANSMISSION ELECTRON MICROSCOPY; ULTRACENTRIFUGATION;

ANIMALS; ATHEROSCLEROSIS; DISEASE MODELS, ANIMAL; HUMANS; LIPOPROTEINS, HDL; MALE; MICE; MICE, INBRED BALB C; MICE, KNOCKOUT; MODELS, MOLECULAR; MOLECULAR STRUCTURE; NANOPARTICLES; PEPTIDES; RECEPTORS, LDL;

EID: 84884189572     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja404714a     Document Type: Article

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