A new HDL mimetic peptide that stimulates cellular cholesterol efflux with high efficiency greatly reduces atherosclerosis in mice

Journal of Lipid Research

Volumn 51, Issue 6, 2010, Pages 1496-1503

  Bielicki, John K ^a   Zhang, Haiyan ^b   Cortez, Yuan ^b   Zheng, Ying ^a   Narayanaswami, Vasanthy ^c   Patel, Arti ^d   Johansson, Jan ^e   Azhar, Salman ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c CHILDREN S HOSPITAL OAKLAND RESEARCH INSTITUTE   (United States)

^d CALIFORNIA STATE UNIVERSITY   (United States)

^e Artery Therapeutic Inc   (United States)

Author keywords

Amphipathic helix; High density lipoprotein; Macrophages; Reverse cholesterol transport

Indexed keywords

AMINO ACID; APOLIPOPROTEIN E; ATI 5261; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN RECEPTOR; PHOSPHOLIPID; SYNTHETIC PEPTIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; AORTA ATHEROSCLEROSIS; AORTA SINUS; ARTICLE; CELL STIMULATION; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; FECES; FOAM CELL; HYPERCHOLESTEROLEMIA; LIPID DIET; MACROPHAGE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT;

AMINO ACID SEQUENCE; ANIMALS; APOLIPOPROTEINS E; ATHEROSCLEROSIS; BIOLOGICAL TRANSPORT; BIOMIMETIC MATERIALS; CHOLESTEROL; DRUG DESIGN; HYPERLIPIDEMIAS; LIPOPROTEINS, HDL; MACROPHAGES; MALE; MICE; MOLECULAR SEQUENCE DATA; PEPTIDES; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SOLUBILITY;

EID: 77952737056     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M003665     Document Type: Article

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