Discoipyrroles A-D: Isolation, structure determination, and synthesis of potent migration inhibitors from Bacillus hunanensis

Journal of the American Chemical Society

Volumn 135, Issue 36, 2013, Pages 13387-13392

  Hu, Youcai ^a,c   Potts, Malia B ^b,c   Colosimo, Dominic ^a   Herrera Herrera, Mireya L ^b   Legako, Aaron G ^a   Yousufuddin, Muhammed ^d   White, Michael A ^b   MacMillan, John B ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^d UNIVERSITY OF TEXAS AT ARLINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLULAR RESPONSE; DISCOIDIN DOMAIN RECEPTOR 2; LUNG CANCER CELLS; MIGRATION INHIBITORS; RECEPTOR TYROSINE KINASE; SIGNALING PATHWAYS; STRUCTURE DETERMINATION; X-RAY CRYSTALLOGRAPHIC ANALYSIS;

AMINO ACIDS; BIOCHEMISTRY; CELL CULTURE; NITROGEN COMPOUNDS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; X RAY CRYSTALLOGRAPHY;

BACTERIOLOGY;

ALKALOID DERIVATIVE; CELL SURFACE RECEPTOR; DISCOIDIN DOMAIN RECEPTOR 2; DISCOIPYRROLE A; DISCOIPYRROLE B; DISCOIPYRROLE C; DISCOIPYRROLE D; PYRROLE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BACILLUS; BACILLUS HUNANENSIS; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG ISOLATION; DRUG POTENCY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; FIBROBLAST; HUMAN; HUMAN CELL; IC 50; MIGRATION INHIBITION; NONHUMAN; ONE POT SYNTHESIS; X RAY CRYSTALLOGRAPHY;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; BACILLUS; BIOLOGICAL PRODUCTS; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; FIBROBLASTS; HETEROCYCLIC COMPOUNDS, 3-RING; HUMANS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PYRROLIDINONES; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTORS, MITOGEN; SIGNAL TRANSDUCTION; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84884171796     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja403412y     Document Type: Article

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