Diverse DNA-cleaving capacities of the jadomycins through precursor-directed biosynthesis

Organic Letters

Volumn 12, Issue 6, 2010, Pages 1172-1175

  Cottreau, Krista M ^a   Spencer, Colin ^a   Wentzell, Jason R ^b   Graham, Cathy L ^b   Borissow, Charles N ^b   Jakeman, David L ^b   McFarland, Sherri A ^a  

^a ACADIA UNIVERSITY   (Canada)

^b DALHOUSIE UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; ISOQUINOLINE DERIVATIVE; JADOMYCIN A; JADOMYCIN B; NAPHTHOQUINONE;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; DNA CLEAVAGE; DNA DAMAGE; DRUG EFFECT; METABOLISM; STEREOISOMERISM; STREPTOMYCES; STRUCTURE ACTIVITY RELATION;

DNA; DNA CLEAVAGE; DNA DAMAGE; ISOQUINOLINES; MOLECULAR STRUCTURE; NAPHTHOQUINONES; STEREOISOMERISM; STREPTOMYCES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 77949833524     PISSN: 15237060     EISSN: 15237052     Source Type: Journal    
DOI: 10.1021/ol902907r     Document Type: Article

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