Nebulised siRNA encapsulated crosslinked chitosan nanoparticles for pulmonary delivery

International Journal of Pharmaceutics

Volumn 455, Issue 1-2, 2013, Pages 241-247

  Sharma, Ketan ^a   Somavarapu, Satyanarayana ^a   Colombani, Agnes ^b   Govind, Nayna ^b   Taylor, Kevin M G ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b ASTRAZENECA   (United Kingdom)

Author keywords

Chitosan; Inhalation; Nanocarrier; Nanoparticle; Nebuliser; siRNA

Indexed keywords

CHITOSAN; FLUORESCEIN ISOTHIOCYANATE; NANOPARTICLE; SMALL INTERFERING RNA;

AEROSOL; ARTICLE; BINDING AFFINITY; CELL PH; CELL STRUCTURE; CELL VIABILITY; CONTROLLED STUDY; CROSS LINKING; CYTOTOXICITY; DRUG CONJUGATION; FREEZE DRYING; GEL ELECTROPHORESIS; GELATION; GENE DELIVERY SYSTEM; HUMAN; HUMAN CELL; HYDRODYNAMICS; MOLECULAR WEIGHT; NANOENCAPSULATION; NEBULIZATION; NEBULIZER; PARTICLE SIZE; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; SURFACE CHARGE;

CHITOSAN; INHALATION; NANOCARRIER; NANOPARTICLE; NEBULISER; SIRNA;

ADMINISTRATION, INHALATION; CELL LINE, TUMOR; CELL SURVIVAL; CHITOSAN; DRUG CARRIERS; HUMANS; HYDROGEN-ION CONCENTRATION; MICROSCOPY, ELECTRON, SCANNING; NANOPARTICLES; NEBULIZERS AND VAPORIZERS; PARTICLE SIZE; RNA, SMALL INTERFERING;

EID: 84884140533     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2013.07.024     Document Type: Article

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